TDMS Study 96006-06 Pathology Tables
NTP Experiment-Test: 96006-06 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02 Study Type: SUBCHRON 90-DAY DIMETHYLAMINOPROPYLCHLORIDE, HYDROCHLORIDE (DMPC) Date: 03/11/02 Route: GAVAGE Time: 14:07:37 Final #1/Mice Facility: BIORELIANCE Chemical CAS #: 5407-04-5 Lock Date: 07/20/01 Cage Range: All Reasons For Removal: All Removal Date Range: All Treatment Groups: Include All a Number of animals examined microscopically at site and number of animals with lesion Page 1 NTP Experiment-Test: 96006-06 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02 Study Type: SUBCHRON 90-DAY DIMETHYLAMINOPROPYLCHLORIDE, HYDROCHLORIDE (DMPC) Date: 03/11/02 Route: GAVAGE Time: 14:07:37 ____________________________________________________________________________________________________________________________________ B6C3F1 MICE FEMALE VEHICLE 6.25 12.5 25 MG/KG 50 MG/KG 100 CONTROL MG/KG MG/KG MG/KG ____________________________________________________________________________________________________________________________________ DISPOSITION SUMMARY Animals Initially in Study 10 10 10 10 10 10 Early Deaths Natural Death 2 Survivors Terminal Sacrifice 10 10 10 10 10 7 Natural Death 1 Animals Examined Microscopically 10 1 1 10 ____________________________________________________________________________________________________________________________________ ALIMENTARY SYSTEM None ____________________________________________________________________________________________________________________________________ CARDIOVASCULAR SYSTEM None ____________________________________________________________________________________________________________________________________ ENDOCRINE SYSTEM None ____________________________________________________________________________________________________________________________________ GENERAL BODY SYSTEM None ____________________________________________________________________________________________________________________________________ GENITAL SYSTEM None ____________________________________________________________________________________________________________________________________ HEMATOPOIETIC SYSTEM None ____________________________________________________________________________________________________________________________________ Page 2 NTP Experiment-Test: 96006-06 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02 Study Type: SUBCHRON 90-DAY DIMETHYLAMINOPROPYLCHLORIDE, HYDROCHLORIDE (DMPC) Date: 03/11/02 Route: GAVAGE Time: 14:07:37 ____________________________________________________________________________________________________________________________________ B6C3F1 MICE FEMALE VEHICLE 6.25 12.5 25 MG/KG 50 MG/KG 100 CONTROL MG/KG MG/KG MG/KG ____________________________________________________________________________________________________________________________________ INTEGUMENTARY SYSTEM None ____________________________________________________________________________________________________________________________________ MUSCULOSKELETAL SYSTEM None ____________________________________________________________________________________________________________________________________ NERVOUS SYSTEM None ____________________________________________________________________________________________________________________________________ RESPIRATORY SYSTEM None ____________________________________________________________________________________________________________________________________ SPECIAL SENSES SYSTEM None ____________________________________________________________________________________________________________________________________ URINARY SYSTEM None Page 3 NTP Experiment-Test: 96006-06 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02 Study Type: SUBCHRON 90-DAY DIMETHYLAMINOPROPYLCHLORIDE, HYDROCHLORIDE (DMPC) Date: 03/11/02 Route: GAVAGE Time: 14:07:37 ____________________________________________________________________________________________________________________________________ B6C3F1 MICE MALE VEHICLE 6.25 12.5 25 MG/KG 50 MG/KG 100 CONTROL MG/KG MG/KG MG/KG ____________________________________________________________________________________________________________________________________ DISPOSITION SUMMARY Animals Initially in Study 10 10 10 10 10 10 Early Deaths Survivors Terminal Sacrifice 10 10 10 10 10 10 Animals Examined Microscopically 10 10 ____________________________________________________________________________________________________________________________________ ALIMENTARY SYSTEM None ____________________________________________________________________________________________________________________________________ CARDIOVASCULAR SYSTEM None ____________________________________________________________________________________________________________________________________ ENDOCRINE SYSTEM None ____________________________________________________________________________________________________________________________________ GENERAL BODY SYSTEM None ____________________________________________________________________________________________________________________________________ GENITAL SYSTEM None ____________________________________________________________________________________________________________________________________ HEMATOPOIETIC SYSTEM None ____________________________________________________________________________________________________________________________________ Page 4 NTP Experiment-Test: 96006-06 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02 Study Type: SUBCHRON 90-DAY DIMETHYLAMINOPROPYLCHLORIDE, HYDROCHLORIDE (DMPC) Date: 03/11/02 Route: GAVAGE Time: 14:07:37 ____________________________________________________________________________________________________________________________________ B6C3F1 MICE MALE VEHICLE 6.25 12.5 25 MG/KG 50 MG/KG 100 CONTROL MG/KG MG/KG MG/KG ____________________________________________________________________________________________________________________________________ INTEGUMENTARY SYSTEM None ____________________________________________________________________________________________________________________________________ MUSCULOSKELETAL SYSTEM None ____________________________________________________________________________________________________________________________________ NERVOUS SYSTEM None ____________________________________________________________________________________________________________________________________ RESPIRATORY SYSTEM None ____________________________________________________________________________________________________________________________________ SPECIAL SENSES SYSTEM None ____________________________________________________________________________________________________________________________________ URINARY SYSTEM None Page 5 ------------------------------------------------------------ ---------- END OF REPORT ---------- ------------------------------------------------------------