E41 - Mean Body Weights and Survival Table (Rats)
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: Battelle Columbus ESTRAGOLE DATE: 10/08/03
EXPERIMENT: 60946 TEST: 01 TIME: 09:08:23
CAGES FROM 0000 TO LAST CAGE PAGE: 1
TEST TYPE: SUBCHRON 90-DAY ROUTE: GAVAGE NTP: C60946
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FINAL/RATS
REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: BATTELLE COLUMBUS ESTRAGOLE DATE: 10/08/03
EXPERIMENT: 60946 TEST: 01 TIME: 9:09:59
SPECIES: RATS, FISCHER 344
TEST TYPE: SUBCHRONIC (90-DAY) ROUTE: ORAL GAVAGE NTP: C60946
CONT: NO1-ES-15460 CAS: 140-67-0
MEAN BODY WEIGHTS AND SURVIVAL OF MALE RATS IN THE
SUBCHRONIC (90-DAY) ORAL GAVAGE STUDY OF ESTRAGOLE
==========================================================================================================================
WEEK 0 MG/KG 37.5 MG/KG 75 MG/KG 150 MG/KG 300 MG/KG
---------------- ---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
==================================================================================================================================
B 89.6 10 89.7 100.1 10 89.2 99.6 10 89.3 99.7 10 88.1 98.3 10
1 89.6 10 89.7 100.1 10 89.2 99.6 10 89.3 99.7 10 88.1 98.3 10
2 120.5 10 122.1 101.3 10 120.9 100.3 10 122.2 101.4 10 116.1 96.3 10
3 151.3 10 152.2 100.6 10 151.6 100.2 10 152.2 100.6 10 143.7 95.0 10
4 183.8 10 186.6 101.5 10 182.6 99.3 10 184.2 100.2 10 171.3 93.2 10
5 207.5 10 210.4 101.4 10 209.4 100.9 10 210.6 101.5 10 190.1 91.6 10
6 229.8 10 231.2 100.6 10 231.9 100.9 10 232.0 101.0 10 208.3 90.6 10
7 246.2 10 249.8 101.5 10 249.8 101.5 10 245.8 99.8 10 219.8 89.3 10
8 268.4 10 270.7 100.9 10 268.6 100.1 10 260.4 97.0 10 235.1 87.6 10
9 280.7 10 284.5 101.4 10 281.8 100.4 10 273.9 97.6 10 246.7 87.9 10
10 292.1 10 295.7 101.2 10 294.3 100.8 10 286.3 98.0 10 252.3 86.4 10
11 305.7 10 310.6 101.6 10 308.2 100.8 10 296.3 96.9 10 257.4 84.2 10
12 315.9 10 324.1 102.6 10 322.7 102.2 10 311.8 98.7 10 268.8 85.1 10
13 327.0 10 332.5 101.7 10 329.4 100.7 10 315.9 96.6 10 277.6 84.9 10
TERM. SAC. 10 10 10 10 10
==========================================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.
MEAN BODY WEIGHTS AND SURVIVAL OF MALE RATS IN THE
SUBCHRONIC (90-DAY) ORAL GAVAGE STUDY OF ESTRAGOLE
===============================
600 MG/KG
WEEK ----------------
AV.WT. PERCENT NO.
(GRAMS) OF CNTL (A)
==============================
B 89.1 99.4 10
1 89.1 99.4 10
2 106.5 88.4 10
3 130.2 86.1 10
4 158.0 86.0 10
5 172.5 83.1 10
6 185.4 80.7 10
7 200.8 81.6 10
8 205.1 76.4 10
9 213.9 76.2 10
10 224.0 76.7 10
11 227.2 74.3 10
12 229.7 72.7 10
13 238.1 72.8 10
TERM. SAC. 10
===============================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.
MEAN BODY WEIGHTS AND SURVIVAL OF FEMALE RATS IN THE
SUBCHRONIC (90-DAY) ORAL GAVAGE STUDY OF ESTRAGOLE
==========================================================================================================================
WEEK 0 MG/KG 37.5 MG/KG 75 MG/KG 150 MG/KG 300 MG/KG
---------------- ---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
==================================================================================================================================
B 81.7 10 82.4 100.9 10 82.7 101.2 10 83.1 101.7 10 82.9 101.5 10
1 81.7 10 82.4 100.9 10 82.7 101.2 10 83.1 101.7 10 82.9 101.5 10
2 101.8 10 102.3 100.5 10 102.8 101.0 10 102.9 101.1 10 100.0 98.2 10
3 118.1 10 113.7 96.3 10 117.0 99.1 10 118.1 100.0 10 115.4 97.7 10
4 130.8 10 131.3 100.4 10 132.4 101.2 10 132.7 101.5 10 129.2 98.8 10
5 141.4 10 142.6 100.8 10 142.8 101.0 10 143.5 101.5 10 137.4 97.2 10
6 150.9 10 152.1 100.8 10 153.6 101.8 10 150.9 100.0 10 145.5 96.4 10
7 160.1 10 161.6 100.9 10 160.9 100.5 10 158.2 98.8 10 152.6 95.3 10
8 165.6 10 168.1 101.5 10 168.6 101.8 10 163.5 98.7 10 158.1 95.5 10
9 171.4 10 173.6 101.3 10 172.7 100.8 10 166.9 97.4 10 160.6 93.7 10
10 174.5 10 175.0 100.3 10 174.9 100.2 10 172.8 99.0 10 163.0 93.4 10
11 180.1 10 182.9 101.6 10 180.6 100.3 10 177.6 98.6 10 168.0 93.3 10
12 186.3 10 189.6 101.8 10 186.5 100.1 10 182.8 98.1 10 175.9 94.4 10
13 192.6 10 192.9 100.2 10 191.0 99.2 10 186.2 96.7 10 177.3 92.1 10
TERM. SAC. 10 10 10 10 10
==========================================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.
MEAN BODY WEIGHTS AND SURVIVAL OF FEMALE RATS IN THE
SUBCHRONIC (90-DAY) ORAL GAVAGE STUDY OF ESTRAGOLE
===============================
600 MG/KG
WEEK ----------------
AV.WT. PERCENT NO.
(GRAMS) OF CNTL (A)
==============================
B 83.0 101.6 10
1 83.0 101.6 10
2 91.5 89.9 10
3 104.4 88.4 10
4 119.0 91.0 10
5 129.5 91.6 10
6 136.7 90.6 10
7 144.0 89.9 10
8 149.7 90.4 10
9 156.2 91.1 10
10 159.5 91.4 10
11 161.1 89.5 10
12 164.3 88.2 10
13 168.1 87.3 10
TERM. SAC. 10
===============================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.