P05 - Incidence Rates of Neoplasms by Anatomic Site (systemic lesions abridged) (Mice)
NTP Experiment-Test: 60946-02 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a) Report: PEIRPT05 Study Type: SUBCHRON 90-DAY ESTRAGOLE Date: 10/08/03 Route: GAVAGE Time: 08:01:07 FINAL/MICE Facility: Battelle Columbus Laboratory Chemical CAS #: 140-67-0 Lock Date: 05/28/02 Cage Range: All Reasons For Removal: All Removal Date Range: All Treatment Groups: Include All a Number of animals examined microscopically at site and number of animals with lesion Page 1 NTP Experiment-Test: 60946-02 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a) Report: PEIRPT05 Study Type: SUBCHRON 90-DAY ESTRAGOLE Date: 10/08/03 Route: GAVAGE Time: 08:01:07 ____________________________________________________________________________________________________________________________________ B6C3F1 MICE FEMALE 0 MG/KG 37.5 75 150 300 600 MG/KG MG/KG MG/KG MG/KG MG/KG ____________________________________________________________________________________________________________________________________ DISPOSITION SUMMARY Animals Initially in Study 10 10 10 10 10 10 Early Deaths Natural Death 8 Moribund Sacrifice 2 Survivors Terminal Sacrifice 10 10 10 10 10 Animals Examined Microscopically 10 10 10 10 10 10 ____________________________________________________________________________________________________________________________________ ALIMENTARY SYSTEM None ____________________________________________________________________________________________________________________________________ CARDIOVASCULAR SYSTEM None ____________________________________________________________________________________________________________________________________ ENDOCRINE SYSTEM None ____________________________________________________________________________________________________________________________________ GENERAL BODY SYSTEM None ____________________________________________________________________________________________________________________________________ GENITAL SYSTEM None ____________________________________________________________________________________________________________________________________ HEMATOPOIETIC SYSTEM None ____________________________________________________________________________________________________________________________________ Page 2 NTP Experiment-Test: 60946-02 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a) Report: PEIRPT05 Study Type: SUBCHRON 90-DAY ESTRAGOLE Date: 10/08/03 Route: GAVAGE Time: 08:01:07 ____________________________________________________________________________________________________________________________________ B6C3F1 MICE FEMALE 0 MG/KG 37.5 75 150 300 600 MG/KG MG/KG MG/KG MG/KG MG/KG ____________________________________________________________________________________________________________________________________ INTEGUMENTARY SYSTEM None ____________________________________________________________________________________________________________________________________ MUSCULOSKELETAL SYSTEM None ____________________________________________________________________________________________________________________________________ NERVOUS SYSTEM None ____________________________________________________________________________________________________________________________________ RESPIRATORY SYSTEM None ____________________________________________________________________________________________________________________________________ SPECIAL SENSES SYSTEM None ____________________________________________________________________________________________________________________________________ URINARY SYSTEM None Page 3 NTP Experiment-Test: 60946-02 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a) Report: PEIRPT05 Study Type: SUBCHRON 90-DAY ESTRAGOLE Date: 10/08/03 Route: GAVAGE Time: 08:01:07 ____________________________________________________________________________________________________________________________________ B6C3F1 MICE MALE 0 MG/KG 37.5 75 150 300 600 MG/KG MG/KG MG/KG MG/KG MG/KG ____________________________________________________________________________________________________________________________________ DISPOSITION SUMMARY Animals Initially in Study 10 10 10 10 10 10 Early Deaths Moribund Sacrifice 1 Survivors Terminal Sacrifice 10 10 10 10 10 9 Animals Examined Microscopically 10 10 10 10 10 10 ____________________________________________________________________________________________________________________________________ ALIMENTARY SYSTEM None ____________________________________________________________________________________________________________________________________ CARDIOVASCULAR SYSTEM None ____________________________________________________________________________________________________________________________________ ENDOCRINE SYSTEM None ____________________________________________________________________________________________________________________________________ GENERAL BODY SYSTEM None ____________________________________________________________________________________________________________________________________ GENITAL SYSTEM None ____________________________________________________________________________________________________________________________________ HEMATOPOIETIC SYSTEM None ____________________________________________________________________________________________________________________________________ Page 4 NTP Experiment-Test: 60946-02 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a) Report: PEIRPT05 Study Type: SUBCHRON 90-DAY ESTRAGOLE Date: 10/08/03 Route: GAVAGE Time: 08:01:07 ____________________________________________________________________________________________________________________________________ B6C3F1 MICE MALE 0 MG/KG 37.5 75 150 300 600 MG/KG MG/KG MG/KG MG/KG MG/KG ____________________________________________________________________________________________________________________________________ INTEGUMENTARY SYSTEM None ____________________________________________________________________________________________________________________________________ MUSCULOSKELETAL SYSTEM None ____________________________________________________________________________________________________________________________________ NERVOUS SYSTEM None ____________________________________________________________________________________________________________________________________ RESPIRATORY SYSTEM None ____________________________________________________________________________________________________________________________________ SPECIAL SENSES SYSTEM None ____________________________________________________________________________________________________________________________________ URINARY SYSTEM None Page 5 ------------------------------------------------------------ ---------- END OF REPORT ---------- ------------------------------------------------------------