TR 346 Mouse Pathology Tables
NTP STATISTICAL ANALYSIS OF SURVIVAL DATA REPORT: PEIRPT11
LAB: Battelle Northwest DATE: 09/10/94
EXP: 05078 ETHYL CHLORIDE TIME: 14:19:25
TEST: 02 CAGES FROM 0000 TO LAST CAGE PAGE: 1
TEST TYPE: CHRONIC ROUTE: RESPIRATORY EXPOSURE WHOLE NTP C#: 06224
CONT: N01ES38061 CAS: 75-00-3
PATHOLOGIST: R. BUSCH
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REASONS FOR REMOVAL:
ALL
REMOVAL DATE RANGE:
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TREATMENT GROUPS:
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NTP STATISTICAL ANALYSIS OF SURVIVAL DATA REPORT: PEIRPT11
LAB: Battelle Northwest DATE: 09/10/94
EXP: 05078 ETHYL CHLORIDE TIME: 14:19:25
TEST: 02 CAGES FROM 0000 TO LAST CAGE
TEST TYPE: CHRONIC ROUTE: RESPIRATORY EXPOSURE WHOLE NTP C#: 06224
CONT: N01ES38061 CAS: 75-00-3
PATHOLOGIST: R. BUSCH
ETHYL CHLORIDE
STATISTICAL ANALYSIS OF SURVIVAL DATA
MALE MICE
FIRST TERMINAL SACRIFICE AT 700 DAYS
INDIVIDUAL SURVIVAL TIMES (DAYS)
==================================================================================
| DOSE = CONTROL |
| --------------------- |
| |
| TOTAL 50 UNCENSORED DEATHS 22 CENSORED DEATHS 0 TERMINAL 28 |
| |
| UNCENSORED DEATHS |
| 17 409 409 413 479 486 516 524 526 526 |
| 560 560 570 578 587 610 629 646 654 658 |
| 668 682 |
| CENSORED DEATHS |
| NONE |
| |
|--------------------------------------------------------------------------------|
| DOSE = 15000 PPM |
| --------------------- |
| |
| TOTAL 50 UNCENSORED DEATHS 39 CENSORED DEATHS 0 TERMINAL 11 |
| |
| UNCENSORED DEATHS |
| 226 257 261 269 278 294 308 329 330 357 |
| 358 360 360 360 363 363 398 409 409 409 |
| 434 448 465 486 502 507 519 524 526 526 |
| 526 559 577 587 596 610 638 671 673 |
| CENSORED DEATHS |
| NONE |
| |
==================================================================================
ETHYL CHLORIDE
STATISTICAL ANALYSIS OF SURVIVAL DATA
MALE MICE
FIRST TERMINAL SACRIFICE AT 700 DAYS
==================================================================================
| KAPLAN-MEIER SURVIVAL PROBABILITY ESTIMATES (%) |
| |
|--------------------------------------------------------------------------------|
| DOSE TIME (DAYS) |
| 90 180 270 365 425 485 545 605 665 700 (A) |
| |
|--------------------------------------------------------------------------------|
| | |
|CONTROL | 98.0 98.0 98.0 98.0 92.0 90.0 80.0 70.0 60.0 56.0 |
| | |
| | |
|15000 PPM | 100.0 100.0 92.0 68.0 60.0 54.0 38.0 30.0 26.0 22.0 |
| | |
| | |
==================================================================================
==================================================================================
| SURVIVAL SUMMARY STATISTICS |
| |
| |
|--------------------------------------------------------------------------------|
| DOSE |
| |
| CONTROL 15000 PPM |
| |
|--------------------------------------------------------------------------------|
|SURVIVAL AT END OF STUDY| 56.0% 22.0% |
|(KAPLAN-MEIER) | |
| | |
|SIGNIFICANCE (B) | P