TDMS Study 91005-07 Pathology Tables
NTP EXP/TEST: 91005-07 METHYLENE BLUE TRIHYDRATE PAGE: 1
TEST TYPE: CHRONIC INITIAL AND CURRENT BODY WEIGHT DATE: 03/25/05
ROUTE: GAVAGE TIME: 09:58:29
EIS REPORT 03
FACILITY: Southern Research Institute
NTP C#: 91005C
CONTRACT NUMBER: N01-ES-05451
CAS NUMBER: 7220-79-3
ANIMAL SUPPLIER: TACONIC FARMS
CAGE RANGE: ALL
DATE RANGE: ALL
REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP EXP/TEST: 91005-07 METHYLENE BLUE TRIHYDRATE PAGE: 2
TEST TYPE: CHRONIC INITIAL AND CURRENT BODY WEIGHT DATE: 03/25/05
ROUTE: GAVAGE EISRPT03 TIME: 09:58:29
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SPECIES-STRAIN: F 344-RATS SEX: FEMALE WEEK ON DOSE: 106 FIRST DOSE: 06/26/00
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-----INITIAL----- ------------CURRENT------------- -----CHANGE------
TREATMENT N MEAN(G) SD N MEAN(G) SD % REL CNTRL N MEAN(G) SD
0 MG/KG 50 95.6 6.5 35 334.6 30.5 35 238.9 30.4
5 MG/KG 50 96.2 6.7 32 339.9 30.3 101.5 32 243.0 30.5
25 MG/KG 50 97.3 7.7 34 304.8 26.0 91.0 34 206.7 25.0
50 MG/KG 50 96.2 6.9 35 294.4 24.2 87.9 35 197.1 23.2
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SPECIES-STRAIN: F 344-RATS SEX: MALE WEEK ON DOSE: 106 FIRST DOSE: 06/26/00
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-----INITIAL----- ------------CURRENT------------- -----CHANGE------
TREATMENT N MEAN(G) SD N MEAN(G) SD % REL CNTRL N MEAN(G) SD
0 MG/KG 50 110.5 9.2 29 500.1 49.5 29 387.5 49.6
5 MG/KG 50 109.4 8.0 33 504.1 33.2 100.7 33 394.6 30.9
25 MG/KG 50 108.9 8.0 39 456.2 35.3 91.2 39 347.7 32.5
50 MG/KG 50 109.8 7.9 30 440.1 38.3 88.0 30 329.3 36.1
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