TDMS Study 91005-08 Pathology Tables
NTP EXP/TEST: 91005-08 METHYLENE BLUE TRIHYDRATE PAGE: 1
TEST TYPE: CHRONIC INITIAL AND CURRENT BODY WEIGHT DATE: 04/26/05
ROUTE: GAVAGE TIME: 09:41:25
EIS REPORT 03
FACILITY: Southern Research Institute
NTP C#: 91005C
CONTRACT NUMBER: N01-ES-05451
CAS NUMBER: 7220-79-3
ANIMAL SUPPLIER: TACONIC FARMS
CAGE RANGE: ALL
DATE RANGE: ALL
REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP EXP/TEST: 91005-08 METHYLENE BLUE TRIHYDRATE PAGE: 2
TEST TYPE: CHRONIC INITIAL AND CURRENT BODY WEIGHT DATE: 04/26/05
ROUTE: GAVAGE EISRPT03 TIME: 09:41:25
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SPECIES-STRAIN: B6C3F1-MICE SEX: FEMALE WEEK ON DOSE: 106 FIRST DOSE: 07/10/00
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-----INITIAL----- ------------CURRENT------------- -----CHANGE------
TREATMENT N MEAN(G) SD N MEAN(G) SD % REL CNTRL N MEAN(G) SD
0 MG/KG 50 18.5 0.7 29 57.0 8.8 29 38.5 8.8
2.5 MG/KG 50 18.5 0.8 40 62.9 4.8 110.3 40 44.4 4.7
12.5 MG/KG 50 18.7 0.7 41 61.8 7.4 108.4 41 43.1 7.4
25 MG/KG 50 18.7 0.8 41 59.0 6.9 103.5 41 40.4 7.0
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SPECIES-STRAIN: B6C3F1-MICE SEX: MALE WEEK ON DOSE: 106 FIRST DOSE: 07/10/00
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-----INITIAL----- ------------CURRENT------------- -----CHANGE------
TREATMENT N MEAN(G) SD N MEAN(G) SD % REL CNTRL N MEAN(G) SD
0 MG/KG 50 22.5 0.8 35 52.6 5.7 35 30.2 5.6
2.5 MG/KG 50 22.5 0.7 38 51.6 7.1 98.0 38 29.2 7.2
12.5 MG/KG 50 22.5 0.7 38 50.9 8.0 96.7 38 28.4 8.2
25 MG/KG 50 22.6 0.8 41 53.8 7.5 102.2 41 31.2 7.4
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