TDMS Study 99034-01 Pathology Tables
NTP EXP/TEST: 99034-01 TRANSGENIC MODEL EVALUATION II (BENZENE) PAGE: 1
TEST TYPE: SUBCHRON 26-WEEK INITIAL AND CURRENT BODY WEIGHT DATE: 11/05/03
ROUTE: GAVAGE TIME: 14:49:27
EIS REPORT 03
FACILITY: Battelle Columbus Laboratory
NTP C#: C99034
CONTRACT NUMBER: N01-ES-65406
CAS NUMBER: 71-43-2
ANIMAL SUPPLIER: TACONIC FARMS
CAGE RANGE: ALL
DATE RANGE: ALL
REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP EXP/TEST: 99034-01 TRANSGENIC MODEL EVALUATION II (BENZENE) PAGE: 2
TEST TYPE: SUBCHRON 26-WEEK INITIAL AND CURRENT BODY WEIGHT DATE: 11/05/03
ROUTE: GAVAGE EISRPT03 TIME: 14:49:27
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SPECIES-STRAIN: TG:P16-INK4A-MICE SEX: FEMALE WEEK ON DOSE: 28 FIRST DOSE: 10/29/99
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-----INITIAL----- ------------CURRENT------------- -----CHANGE------
TREATMENT N MEAN(G) SD N MEAN(G) SD % REL CNTRL N MEAN(G) SD
0 MG/KG 15 20.0 1.3 15 30.4 5.5 15 10.4 5.0
25 MG/KG 15 20.0 1.4 15 28.7 4.5 94.4 15 8.6 3.8
50 MG/KG 15 20.0 1.1 15 29.3 3.5 96.3 15 9.3 3.8
100 MG/KG 15 20.1 1.3 15 29.7 4.2 97.6 15 9.6 4.1
200 MG/KG 15 20.3 1.2 15 27.3 1.8 89.8 15 7.0 2.1
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SPECIES-STRAIN: TG:P16-INK4A-MICE SEX: MALE WEEK ON DOSE: 28 FIRST DOSE: 10/29/99
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-----INITIAL----- ------------CURRENT------------- -----CHANGE------
TREATMENT N MEAN(G) SD N MEAN(G) SD % REL CNTRL N MEAN(G) SD
0 MG/KG 15 25.4 1.6 15 45.3 5.1 15 19.8 4.7
25 MG/KG 15 25.1 1.6 15 40.0 5.7 88.3 15 14.9 4.9
50 MG/KG 15 24.9 1.4 15 39.3 3.9 86.7 15 14.4 3.1
100 MG/KG 15 24.8 2.0 15 33.5 3.6 73.9 15 8.7 2.7
200 MG/KG 15 25.1 2.1 14 32.1 3.5 70.8 14 7.2 2.3
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