TDMS Study 99036-01 Pathology Tables
NTP EXP/TEST: 99036-01 TRANSGENIC MODEL EVALUATION II (PHENOLPHTHALEIN) PAGE: 1
TEST TYPE: SUBCHRON 26-WEEK INITIAL AND CURRENT BODY WEIGHT DATE: 04/21/04
ROUTE: DOSED FEED TIME: 08:28:43
EIS REPORT 03
FACILITY: Battelle Columbus Laboratory
NTP C#: C99036
CONTRACT NUMBER: N01-ES-65406
CAS NUMBER: 77-09-08
ANIMAL SUPPLIER: TACONIC FARMS
CAGE RANGE: ALL
DATE RANGE: ALL
REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP EXP/TEST: 99036-01 TRANSGENIC MODEL EVALUATION II (PHENOLPHTHALEIN) PAGE: 2
TEST TYPE: SUBCHRON 26-WEEK INITIAL AND CURRENT BODY WEIGHT DATE: 04/21/04
ROUTE: DOSED FEED EISRPT03 TIME: 08:28:43
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SPECIES-STRAIN: TG:P16-INK4A-MICE SEX: FEMALE WEEK ON DOSE: 27 FIRST DOSE: 12/08/99
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-----INITIAL----- ------------CURRENT------------- -----CHANGE------
TREATMENT N MEAN(G) SD N MEAN(G) SD % REL CNTRL N MEAN(G) SD
0 PPM 15 16.4 0.6 15 25.3 1.8 15 8.9 1.8
200 PPM 15 16.4 1.1 13 25.5 1.0 100.7 13 9.1 0.7
375 PPM 15 16.4 0.8 14 26.5 2.7 104.7 14 10.2 2.3
750 PPM 15 16.5 0.8 15 25.1 1.5 99.2 15 8.6 1.7
3000 PPM 15 16.5 1.0 14 25.1 1.2 99.2 14 8.7 1.4
12,000 PPM 15 16.5 1.0 15 25.4 1.1 100.3 15 8.8 1.1
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SPECIES-STRAIN: TG:P16-INK4A-MICE SEX: MALE WEEK ON DOSE: 27 FIRST DOSE: 12/08/99
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-----INITIAL----- ------------CURRENT------------- -----CHANGE------
TREATMENT N MEAN(G) SD N MEAN(G) SD % REL CNTRL N MEAN(G) SD
0 PPM 15 20.1 0.7 13 34.3 4.0 13 14.0 4.1
200 PPM 15 20.0 0.8 15 36.0 3.7 104.9 15 16.0 3.4
375 PPM 15 19.9 0.8 15 35.4 3.3 103.2 15 15.5 2.8
750 PPM 15 20.0 0.9 13 35.9 2.4 104.6 13 15.7 2.1
3000 PPM 15 19.9 0.9 15 33.6 3.1 97.9 15 13.8 2.8
12,000 PPM 15 19.6 0.7 14 30.3 2.0 88.3 14 10.7 2.0
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