TDMS Study 99035-01 Pathology Tables
NTP EXP/TEST: 99035-01 TRANSGENIC MODEL EVALUATION II (GLYCIDOL) PAGE: 1 TEST TYPE: 26-39 WEEKS INITIAL AND CURRENT BODY WEIGHT DATE: 03/31/04 ROUTE: GAVAGE TIME: 13:02:16 EIS REPORT 03 FINAL #1 FACILITY: Battelle Columbus Laboratory NTP C#: C99035 CONTRACT NUMBER: N01-ES-65406 CAS NUMBER: 556-52-5 ANIMAL SUPPLIER: TACONIC FARMS CAGE RANGE: ALL DATE RANGE: ALL REASONS FOR REMOVAL: ALL REMOVAL DATE RANGE: ALL TREATMENT GROUPS: INCLUDE ALL NTP EXP/TEST: 99035-01 TRANSGENIC MODEL EVALUATION II (GLYCIDOL) PAGE: 2 TEST TYPE: 26-39 WEEKS INITIAL AND CURRENT BODY WEIGHT DATE: 03/31/04 ROUTE: GAVAGE EISRPT03 TIME: 13:02:16 ---------------------------------------------------------------------------------------------------------------------------------- SPECIES-STRAIN: TG:P16-INK4A-MICE SEX: FEMALE WEEK ON DOSE: 41 FIRST DOSE: 02/03/00 ---------------------------------------------------------------------------------------------------------------------------------- -----INITIAL----- ------------CURRENT------------- -----CHANGE------ TREATMENT N MEAN(G) SD N MEAN(G) SD % REL CNTRL N MEAN(G) SD 0 MG/KG 15 21.3 1.1 13 41.8 7.3 13 20.4 6.7 25 MG/KG 15 21.5 1.0 14 39.4 4.6 94.2 14 18.1 4.6 50 MG/KG 15 21.4 0.8 12 37.4 5.0 89.4 12 15.9 4.6 100 MG/KG 15 21.5 1.0 14 34.5 4.2 82.5 14 13.0 3.8 200 MG/KG 15 21.6 0.9 9 31.1 3.4 74.4 9 9.2 3.4 ---------------------------------------------------------------------------------------------------------------------------------- SPECIES-STRAIN: TG:P16-INK4A-MICE SEX: MALE WEEK ON DOSE: 41 FIRST DOSE: 02/03/00 ---------------------------------------------------------------------------------------------------------------------------------- -----INITIAL----- ------------CURRENT------------- -----CHANGE------ TREATMENT N MEAN(G) SD N MEAN(G) SD % REL CNTRL N MEAN(G) SD 0 MG/KG 15 27.4 1.4 13 48.7 2.6 13 21.5 2.1 25 MG/KG 15 27.0 1.3 14 47.9 4.1 98.3 14 20.9 3.3 50 MG/KG 15 27.3 1.6 13 48.3 1.8 99.1 13 21.2 1.5 100 MG/KG 15 27.1 1.3 14 47.5 3.4 97.5 14 20.3 3.0 200 MG/KG 15 27.5 1.8 7 39.8 5.8 81.7 7 12.5 5.3 ----------------------------------- ---------- END-OF-REPORT ---------- -----------------------------------