TDMS Study 92013-03 Pathology Tables
NTP Experiment-Test: 92013-03 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02 Study Type: SUBCHRON 90-DAY 4-METHYLIMIDAZOLE Date: 08/06/96 Route: DOSED FEED Time: 20:37:53 90-DAY SUBCHRONIC Facility: Microbiological Associates Chemical CAS #: 822-36-6 Lock Date: 01/12/95 Cage Range: All Reasons For Removal: All Removal Date Range: All Treatment Groups: Include All a Number of animals examined microscopically at site and number of animals with lesion Page 1 NTP Experiment-Test: 92013-03 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02 Study Type: SUBCHRON 90-DAY 4-METHYLIMIDAZOLE Date: 08/06/96 Route: DOSED FEED Time: 20:37:53 ____________________________________________________________________________________________________________________________________ FISCHER 344 RATS FEMALE UNTREAT 625 1250 2500 5000 10000 CONTROL PPM PPM PPM PPM PPM ____________________________________________________________________________________________________________________________________ DISPOSITION SUMMARY Animals Initially in Study 10 10 10 10 10 10 Early Deaths Moribund Sacrifice 1 Survivors Terminal Sacrifice 3 2 2 2 2 Accidently Killed 7 8 7 8 8 10 Animals Examined Microscopically 10 2 5 10 10 10 ____________________________________________________________________________________________________________________________________ ALIMENTARY SYSTEM None ____________________________________________________________________________________________________________________________________ CARDIOVASCULAR SYSTEM None ____________________________________________________________________________________________________________________________________ ENDOCRINE SYSTEM None ____________________________________________________________________________________________________________________________________ GENERAL BODY SYSTEM None ____________________________________________________________________________________________________________________________________ GENITAL SYSTEM None ____________________________________________________________________________________________________________________________________ HEMATOPOIETIC SYSTEM None ____________________________________________________________________________________________________________________________________ INTEGUMENTARY SYSTEM None ____________________________________________________________________________________________________________________________________ Page 2 NTP Experiment-Test: 92013-03 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02 Study Type: SUBCHRON 90-DAY 4-METHYLIMIDAZOLE Date: 08/06/96 Route: DOSED FEED Time: 20:37:53 ____________________________________________________________________________________________________________________________________ FISCHER 344 RATS FEMALE UNTREAT 625 1250 2500 5000 10000 CONTROL PPM PPM PPM PPM PPM ____________________________________________________________________________________________________________________________________ MUSCULOSKELETAL SYSTEM None ____________________________________________________________________________________________________________________________________ NERVOUS SYSTEM None ____________________________________________________________________________________________________________________________________ RESPIRATORY SYSTEM None ____________________________________________________________________________________________________________________________________ SPECIAL SENSES SYSTEM None ____________________________________________________________________________________________________________________________________ URINARY SYSTEM None Page 3 NTP Experiment-Test: 92013-03 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02 Study Type: SUBCHRON 90-DAY 4-METHYLIMIDAZOLE Date: 08/06/96 Route: DOSED FEED Time: 20:37:53 ____________________________________________________________________________________________________________________________________ FISCHER 344 RATS MALE UNTREAT 625 1250 2500 5000 10000 CONTROL PPM PPM PPM PPM PPM ____________________________________________________________________________________________________________________________________ DISPOSITION SUMMARY Animals Initially in Study 10 10 10 10 10 10 Early Deaths Natural Death 1 Survivors Terminal Sacrifice 10 9 9 10 3 2 Accidently Killed 1 1 7 7 Animals Examined Microscopically 10 3 10 10 10 10 ____________________________________________________________________________________________________________________________________ ALIMENTARY SYSTEM None ____________________________________________________________________________________________________________________________________ CARDIOVASCULAR SYSTEM None ____________________________________________________________________________________________________________________________________ ENDOCRINE SYSTEM None ____________________________________________________________________________________________________________________________________ GENERAL BODY SYSTEM None ____________________________________________________________________________________________________________________________________ GENITAL SYSTEM None ____________________________________________________________________________________________________________________________________ HEMATOPOIETIC SYSTEM None ____________________________________________________________________________________________________________________________________ INTEGUMENTARY SYSTEM None ____________________________________________________________________________________________________________________________________ Page 4 NTP Experiment-Test: 92013-03 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02 Study Type: SUBCHRON 90-DAY 4-METHYLIMIDAZOLE Date: 08/06/96 Route: DOSED FEED Time: 20:37:53 ____________________________________________________________________________________________________________________________________ FISCHER 344 RATS MALE UNTREAT 625 1250 2500 5000 10000 CONTROL PPM PPM PPM PPM PPM ____________________________________________________________________________________________________________________________________ MUSCULOSKELETAL SYSTEM None ____________________________________________________________________________________________________________________________________ NERVOUS SYSTEM None ____________________________________________________________________________________________________________________________________ RESPIRATORY SYSTEM None ____________________________________________________________________________________________________________________________________ SPECIAL SENSES SYSTEM None ____________________________________________________________________________________________________________________________________ URINARY SYSTEM None Page 5 ------------------------------------------------------------ ---------- END OF REPORT ---------- ------------------------------------------------------------