TDMS Study 92012-04 Pathology Tables

NTP Experiment-Test: 92012-04               INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a)                     Report: PEIRPT02
Study Type: SUBCHRON 90-DAY                                 2-METHYLIMIDAZOLE                                     Date: 08/06/96
Route: DOSED FEED                                                                                                 Time: 20:29:51
                                                             90-DAY
       Facility:  Microbiological Associates
       Chemical CAS #:  693-98-1
       Lock Date:  08/31/94
       Cage Range:  All
       Reasons For Removal:    All
       Removal Date Range:     All
       Treatment Groups:       Include All
a  Number of animals examined microscopically at site and number of animals with lesion
                                                              Page   1
NTP Experiment-Test: 92012-04               INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a)                     Report: PEIRPT02
Study Type: SUBCHRON 90-DAY                                 2-METHYLIMIDAZOLE                                     Date: 08/06/96  
Route: DOSED FEED                                                                                                 Time: 20:29:51  
____________________________________________________________________________________________________________________________________
         B6C3F1 MICE FEMALE                        UNTREAT      625          1250         2500         5000         10000           
                                                   CONTROL      PPM          PPM          PPM          PPM          PPM             
____________________________________________________________________________________________________________________________________
DISPOSITION SUMMARY                                                                                                                 
  Animals Initially in Study                          10           10           10           10           10           10           
  Early Deaths                                                                                                                      
  Survivors                                                                                                                         
    Terminal Sacrifice                                10           10            9           10           10            8           
    Accidently Killed                                                            1                                      2           
  Animals Examined Microscopically                    10           10           10           10           10           10           
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 ALIMENTARY SYSTEM                                                                                                                  
   None                                                                                                                             
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 CARDIOVASCULAR SYSTEM                                                                                                              
   None                                                                                                                             
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 ENDOCRINE SYSTEM                                                                                                                   
   None                                                                                                                             
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 GENERAL BODY SYSTEM                                                                                                                
   None                                                                                                                             
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 GENITAL SYSTEM                                                                                                                     
   None                                                                                                                             
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 HEMATOPOIETIC SYSTEM                                                                                                               
   None                                                                                                                             
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 INTEGUMENTARY SYSTEM                                                                                                               
   None                                                                                                                             
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                                                             Page   2                                                               
NTP Experiment-Test: 92012-04               INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a)                     Report: PEIRPT02
Study Type: SUBCHRON 90-DAY                                 2-METHYLIMIDAZOLE                                     Date: 08/06/96  
Route: DOSED FEED                                                                                                 Time: 20:29:51  
____________________________________________________________________________________________________________________________________
         B6C3F1 MICE FEMALE                        UNTREAT      625          1250         2500         5000         10000           
                                                   CONTROL      PPM          PPM          PPM          PPM          PPM             
____________________________________________________________________________________________________________________________________
 MUSCULOSKELETAL SYSTEM                                                                                                             
   None                                                                                                                             
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 NERVOUS SYSTEM                                                                                                                     
   None                                                                                                                             
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 RESPIRATORY SYSTEM                                                                                                                 
   None                                                                                                                             
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 SPECIAL SENSES SYSTEM                                                                                                              
   None                                                                                                                             
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 URINARY SYSTEM                                                                                                                     
   None                                                                                                                             
                                                             Page   3                                                               
NTP Experiment-Test: 92012-04               INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a)                     Report: PEIRPT02
Study Type: SUBCHRON 90-DAY                                 2-METHYLIMIDAZOLE                                     Date: 08/06/96  
Route: DOSED FEED                                                                                                 Time: 20:29:51  
____________________________________________________________________________________________________________________________________
         B6C3F1 MICE MALE                          UNTREAT      625          1250         2500         5000         10000           
                                                   CONTROL      PPM          PPM          PPM          PPM          PPM             
____________________________________________________________________________________________________________________________________
DISPOSITION SUMMARY                                                                                                                 
  Animals Initially in Study                          10           10           10           10           10           10           
  Early Deaths                                                                                                                      
  Survivors                                                                                                                         
    Terminal Sacrifice                                10            9            9           10           10            9           
    Accidently Killed                                               1            1                                      1           
  Animals Examined Microscopically                    10           10           10           10           10           10           
____________________________________________________________________________________________________________________________________
 ALIMENTARY SYSTEM                                                                                                                  
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
 CARDIOVASCULAR SYSTEM                                                                                                              
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
 ENDOCRINE SYSTEM                                                                                                                   
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
 GENERAL BODY SYSTEM                                                                                                                
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
 GENITAL SYSTEM                                                                                                                     
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
 HEMATOPOIETIC SYSTEM                                                                                                               
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
 INTEGUMENTARY SYSTEM                                                                                                               
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                             Page   4                                                               
NTP Experiment-Test: 92012-04               INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a)                     Report: PEIRPT02
Study Type: SUBCHRON 90-DAY                                 2-METHYLIMIDAZOLE                                     Date: 08/06/96  
Route: DOSED FEED                                                                                                 Time: 20:29:51  
____________________________________________________________________________________________________________________________________
         B6C3F1 MICE MALE                          UNTREAT      625          1250         2500         5000         10000           
                                                   CONTROL      PPM          PPM          PPM          PPM          PPM             
____________________________________________________________________________________________________________________________________
 MUSCULOSKELETAL SYSTEM                                                                                                             
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
 NERVOUS SYSTEM                                                                                                                     
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
 RESPIRATORY SYSTEM                                                                                                                 
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
 SPECIAL SENSES SYSTEM                                                                                                              
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
 URINARY SYSTEM                                                                                                                     
   None                                                                                                                             
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