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TDMS Study 05162-10 Pathology Tables

NTP  EXP/TEST: 05162-10                                  DIETHANOLAMINE                                           PAGE: 1
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 06/11/96
ROUTE: SKIN APPLICATION                                                                                           TIME: 09:23:54

                                                         EIS REPORT 37


       FACILITY:  Battelle Columbus Laboratory

       NTP C#:  55174D

       CONTRACT NUMBER:  N01-ES-05293

       CAS NUMBER:  111-42-2

       ANIMAL SUPPLIER:  NOT SPECIFIED

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL
NTP  EXP/TEST: 05162-10                                  DIETHANOLAMINE                                           PAGE: 2
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 06/11/96
ROUTE: SKIN APPLICATION                                     EISRPT37                                              TIME: 09:23:54
------------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: MICE-B6C3F1                         TRT#: 2                      ROOM/AREA:    205         FIRST DOSE: 10/22/90
            SEX: FEMALE                               TRT: 0 MG/KG            PROCEDURE SET:      1
------------------------------------------------------------------------------------------------------------------------------------
                FIRST OCCUR'D  LAST  OCCUR'D  FREQ/
CAGE     ANIMAL  DAY    DATE    DAY    DATE  TOT OBS CLINICAL OBSERVATION
----     ------ -------------  ------------- ------- --------------------

247         247  725 10/15/92   725 10/15/92   1/1   Irritation Site of Applic
NTP  EXP/TEST: 05162-10                                  DIETHANOLAMINE                                           PAGE: 3
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 06/11/96
ROUTE: SKIN APPLICATION                                     EISRPT37                                              TIME: 09:23:54
------------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: MICE-B6C3F1                         TRT#: 4                      ROOM/AREA:    205         FIRST DOSE: 10/22/90
            SEX: FEMALE                               TRT: 40 MG/KG           PROCEDURE SET:      1
------------------------------------------------------------------------------------------------------------------------------------
                FIRST OCCUR'D  LAST  OCCUR'D  FREQ/
CAGE     ANIMAL  DAY    DATE    DAY    DATE  TOT OBS CLINICAL OBSERVATION
----     ------ -------------  ------------- ------- --------------------





                              THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP  EXP/TEST: 05162-10                                  DIETHANOLAMINE                                           PAGE: 4
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 06/11/96
ROUTE: SKIN APPLICATION                                     EISRPT37                                              TIME: 09:23:54
------------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: MICE-B6C3F1                         TRT#: 6                      ROOM/AREA:    205         FIRST DOSE: 10/22/90
            SEX: FEMALE                               TRT: 80 MG/KG           PROCEDURE SET:      1
------------------------------------------------------------------------------------------------------------------------------------
                FIRST OCCUR'D  LAST  OCCUR'D  FREQ/
CAGE     ANIMAL  DAY    DATE    DAY    DATE  TOT OBS CLINICAL OBSERVATION
----     ------ -------------  ------------- ------- --------------------





                              THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP  EXP/TEST: 05162-10                                  DIETHANOLAMINE                                           PAGE: 5
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 06/11/96
ROUTE: SKIN APPLICATION                                     EISRPT37                                              TIME: 09:23:54
------------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: MICE-B6C3F1                         TRT#: 8                      ROOM/AREA:    205         FIRST DOSE: 10/22/90
            SEX: FEMALE                               TRT: 160     MG/KG      PROCEDURE SET:      1
------------------------------------------------------------------------------------------------------------------------------------
                FIRST OCCUR'D  LAST  OCCUR'D  FREQ/
CAGE     ANIMAL  DAY    DATE    DAY    DATE  TOT OBS CLINICAL OBSERVATION
----     ------ -------------  ------------- ------- --------------------





                              THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP  EXP/TEST: 05162-10                                  DIETHANOLAMINE                                           PAGE: 6
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 06/11/96
ROUTE: SKIN APPLICATION                                     EISRPT37                                              TIME: 09:23:54
------------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: MICE-B6C3F1                         TRT#: 1                      ROOM/AREA:    205         FIRST DOSE: 10/22/90
            SEX: MALE                                 TRT: 0 MG/KG            PROCEDURE SET:      1
------------------------------------------------------------------------------------------------------------------------------------
                FIRST OCCUR'D  LAST  OCCUR'D  FREQ/
CAGE     ANIMAL  DAY    DATE    DAY    DATE  TOT OBS CLINICAL OBSERVATION
----     ------ -------------  ------------- ------- --------------------





                              THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP  EXP/TEST: 05162-10                                  DIETHANOLAMINE                                           PAGE: 7
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 06/11/96
ROUTE: SKIN APPLICATION                                     EISRPT37                                              TIME: 09:23:54
------------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: MICE-B6C3F1                         TRT#: 3                      ROOM/AREA:    205         FIRST DOSE: 10/22/90
            SEX: MALE                                 TRT: 40 MG/KG           PROCEDURE SET:      1
------------------------------------------------------------------------------------------------------------------------------------
                FIRST OCCUR'D  LAST  OCCUR'D  FREQ/
CAGE     ANIMAL  DAY    DATE    DAY    DATE  TOT OBS CLINICAL OBSERVATION
----     ------ -------------  ------------- ------- --------------------





                              THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP  EXP/TEST: 05162-10                                  DIETHANOLAMINE                                           PAGE: 8
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 06/11/96
ROUTE: SKIN APPLICATION                                     EISRPT37                                              TIME: 09:23:54
------------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: MICE-B6C3F1                         TRT#: 5                      ROOM/AREA:    205         FIRST DOSE: 10/22/90
            SEX: MALE                                 TRT: 80 MG/KG           PROCEDURE SET:      1
------------------------------------------------------------------------------------------------------------------------------------
                FIRST OCCUR'D  LAST  OCCUR'D  FREQ/
CAGE     ANIMAL  DAY    DATE    DAY    DATE  TOT OBS CLINICAL OBSERVATION
----     ------ -------------  ------------- ------- --------------------





                              THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP  EXP/TEST: 05162-10                                  DIETHANOLAMINE                                           PAGE: 9
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 06/11/96
ROUTE: SKIN APPLICATION                                     EISRPT37                                              TIME: 09:23:54
------------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: MICE-B6C3F1                         TRT#: 7                      ROOM/AREA:    205         FIRST DOSE: 10/22/90
            SEX: MALE                                 TRT: 160     MG/KG      PROCEDURE SET:      1
------------------------------------------------------------------------------------------------------------------------------------
                FIRST OCCUR'D  LAST  OCCUR'D  FREQ/
CAGE     ANIMAL  DAY    DATE    DAY    DATE  TOT OBS CLINICAL OBSERVATION
----     ------ -------------  ------------- ------- --------------------





                              THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.

                                               -----------------------------------
                                               ---------- END-OF-REPORT ----------
                                               -----------------------------------