TDMS Study 05187-06 Pathology Tables
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: Battelle Columbus METHYLEUGENOL DATE: 07/20/98
EXPERIMENT: 05187 TEST: 06 TIME: 10:14:15
CAGES FROM 0000 TO LAST CAGE PAGE: 1
TEST TYPE: CHRONIC ROUTE: GAVAGE NTP: C60991B
CONT: NO1-ES-25337 CAS: 93-15-2
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REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: BATTELLE COLUMBUS LABORATORY METHYLEUGENOL DATE: 07/20/98
EXPERIMENT: 05187 TEST: 06 TIME: 10:21:34
TEST TYPE: TWO YEAR ROUTE: ORAL GAVAGE NTP: 60991B
CONT: NO1-ES-25337 CAS: 93-15-2
MEAN BODY WEIGHTS AND SURVIVAL OF MALE MICE IN THE
TWO YEAR ORAL GAVAGE STUDY OF METHYLEUGENOL
==========================================================================================================
WEEK 0 MG/KG 37 MG/KG 75 MG/KG 150 MG/KG
---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
=========================================================================================================
B 24.4 50 24.2 99.2 50 24.2 99.2 50 24.2 99.2 50
1 24.4 50 24.2 99.2 50 24.2 99.2 50 24.2 99.2 50
5 28.9 50 28.9 100.0 50 28.4 98.3 50 28.5 98.6 50
9 33.2 50 33.6 101.2 50 32.9 99.1 49 32.7 98.5 50
13 37.4 50 37.6 100.5 50 36.8 98.4 49 36.0 96.3 50
17 41.4 50 41.8 101.0 50 40.4 97.6 49 39.4 95.2 50
21 45.4 50 45.0 99.1 50 43.4 95.6 49 42.1 92.7 50
25 47.0 50 46.5 98.9 50 45.0 95.7 49 43.6 92.8 50
29 48.0 50 47.8 99.6 50 46.1 96.0 49 44.8 93.3 50
33 49.8 50 48.8 98.0 50 47.5 95.4 49 46.8 94.0 50
37 50.6 50 49.8 98.4 50 48.1 95.1 49 47.3 93.5 50
41 50.7 50 50.2 99.0 50 48.7 96.1 49 47.8 94.3 50
45 51.7 50 50.3 97.3 50 48.8 94.4 49 48.7 94.2 50
49 52.5 50 51.0 97.1 50 49.3 93.9 48 49.3 93.9 50
53 52.3 50 51.5 98.5 50 49.7 95.0 48 49.4 94.5 49
57 52.4 50 51.1 97.5 50 48.9 93.3 48 49.4 94.3 49
61 52.6 50 51.7 98.3 50 49.4 93.9 48 49.1 93.3 49
65 52.9 49 51.8 97.9 50 49.6 93.8 48 49.9 94.3 49
69 52.2 48 51.5 98.7 50 49.1 94.1 48 49.7 95.2 48
73 51.9 48 51.0 98.3 49 49.4 95.2 47 49.2 94.8 48
77 51.7 47 50.5 97.7 49 48.9 94.6 45 48.5 93.8 47
81 52.8 44 50.4 95.5 48 48.9 92.6 45 48.6 92.0 44
85 53.6 41 50.5 94.2 48 49.6 92.5 42 49.9 93.1 41
89 53.7 40 50.3 93.7 45 49.3 91.8 41 48.8 90.9 40
93 53.1 40 49.1 92.5 44 48.3 91.0 39 48.2 90.8 40
97 52.4 39 47.8 91.2 41 46.1 88.0 39 46.9 89.5 39
101 52.2 38 47.1 90.2 38 44.0 84.3 38 45.4 87.0 37
TERM. SAC. 38 36 37 35
==========================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.
MEAN BODY WEIGHTS AND SURVIVAL OF FEMALE MICE IN THE
TWO YEAR ORAL GAVAGE STUDY OF METHYLEUGENOL
==========================================================================================================
WEEK 0 MG/KG 37 MG/KG 75 MG/KG 150 MG/KG
---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
=========================================================================================================
B 19.1 50 19.2 100.5 50 19.2 100.5 50 19.3 101.0 50
1 19.1 50 19.2 100.5 50 19.2 100.5 50 19.3 101.0 50
5 23.0 50 22.8 99.1 50 22.6 98.3 50 22.5 97.8 50
9 26.8 50 25.9 96.6 50 25.6 95.5 50 24.8 92.5 50
13 29.4 50 29.6 100.7 50 28.8 98.0 50 26.6 90.5 50
17 34.7 50 34.3 98.8 50 33.0 95.1 50 28.8 83.0 50
21 38.6 50 37.6 97.4 50 35.6 92.2 50 31.0 80.3 50
25 40.5 50 39.7 98.0 50 37.6 92.8 50 32.9 81.2 50
29 43.6 49 42.5 97.5 50 40.1 92.0 50 35.0 80.3 50
33 47.1 49 44.7 94.9 50 42.4 90.0 50 37.1 78.8 50
37 49.2 49 45.4 92.3 50 43.1 87.6 50 36.8 74.8 50
41 50.1 49 46.6 93.0 50 43.4 86.6 50 37.9 75.6 50
45 51.6 49 47.7 92.4 50 44.6 86.4 50 39.5 76.6 50
49 53.9 49 50.1 92.9 50 46.2 85.7 50 41.1 76.3 50
53 54.0 49 50.0 92.6 50 45.6 84.4 50 39.7 73.5 50
57 56.9 49 51.0 89.6 50 46.6 81.9 49 40.6 71.4 49
61 58.3 49 52.3 89.7 50 47.0 80.6 49 40.8 70.0 49
65 59.0 49 52.4 88.8 50 45.6 77.3 49 39.0 66.1 49
69 60.1 49 52.2 86.9 49 44.0 73.2 48 37.9 63.1 47
73 59.0 49 51.7 87.6 48 42.5 72.0 46 35.3 59.8 47
77 60.1 49 49.7 82.7 46 40.8 67.9 44 36.1 60.1 44
81 61.7 49 47.1 76.3 46 38.5 62.4 43 35.6 57.7 42
85 63.2 47 44.0 69.6 41 36.8 58.2 42 34.7 54.9 40
89 62.7 46 43.0 68.6 36 34.6 55.2 39 34.6 55.2 34
93 61.7 44 40.5 65.6 31 34.1 55.3 34 33.7 54.6 29
97 61.1 39 38.0 62.2 26 34.8 57.0 29 32.9 53.8 23
101 60.9 36 37.4 61.4 23 34.2 56.2 25 33.0 54.2 10
TERM. SAC. 31 18 18 3
==========================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.