TDMS Study 05187-09 Pathology Tables
NTP Experiment-Test: 05187-09 NEOPLASMS BY INDIVIDUAL ANIMAL Report: PEIRPT04
Study Type: CHRONIC METHYLEUGENOL Date: 07/20/98
Route: GAVAGE Time: 08:39:31
27 WEEK SSAC
Facility: Battelle Columbus Laboratory
Chemical CAS #: 93-15-2
Lock Date: 09/17/96
Cage Range: All
Reasons For Removal: 25017 Scheduled Sacrifice
Removal Date Range: 08/09/94 - 08/10/94
Treatment Groups: Include 002 0 MG/KG
Include 010 300 MG/KG
Include 001 0 MG/KG
Include 009 300 MG/KG
Note: Animals arranged according to CID number
Page 1
NTP Experiment-Test: 05187-09 NEOPLASMS BY INDIVIDUAL ANIMAL Report: PEIRPT04
Study Type: CHRONIC METHYLEUGENOL Date: 07/20/98
Route: GAVAGE Time: 08:39:31
__________________________________________________________________________________________________________________________________
| 1| 1| 1| 1| 1| | |
DAY ON TEST | 8| 8| 8| 8| 8| | |
| 4| 4| 4| 4| 4| | |
_____________________________________________________________________________________________________________________| T (*) |
| 0| 0| 0| 0| 0| | O |
FISCHER 344 RATS FEMALE | 0| 0| 0| 0| 0| | T |
ANIMAL ID | 2| 3| 3| 3| 3| | A |
0 MG/KG | 8| 0| 0| 1| 3| | L |
| 6| 0| 2| 3| 0| | |
__________________________________________________________________________________________________________________________________
ALIMENTARY SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Esophagus | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Large, Colon | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Large, Rectum | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Large, Cecum | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Small, Duodenum | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Small, Jejunum | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Small, Ileum | + + + + + | 5 |
__________________________________________________________________________|____________|
Liver | + + + + + | 5 |
__________________________________________________________________________|____________|
Pancreas | + + + + + | 5 |
__________________________________________________________________________|____________|
Salivary Glands | + + + + + | 5 |
__________________________________________________________________________|____________|
Stomach, Forestomach | + + + + + | 5 |
__________________________________________________________________________|____________|
Stomach, Glandular | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
CARDIOVASCULAR SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Blood Vessel | + + + + + | 5 |
__________________________________________________________________________|____________|
Heart | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
ENDOCRINE SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Adrenal Cortex | + + + + + | 5 |
__________________________________________________________________________|____________|
Adrenal Medulla | + + + + + | 5 |
__________________________________________________________________________|____________|
Islets, Pancreatic | + + + + + | 5 |
__________________________________________________________________________|____________|
Parathyroid Gland | + M + + + | 4 |
__________________________________________________________________________|____________|
Pituitary Gland | + + + + + | 5 |
__________________________________________________________________________|____________|
Thyroid Gland | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
GENERAL BODY SYSTEM | | |
| | |
None | | |
_____________________________________________________________________________________________________________________| |
GENITAL SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Clitoral Gland | + + + + + | 5 |
__________________________________________________________________________|____________|
Ovary | + + + + + | 5 |
__________________________________________________________________________|____________|
Uterus | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
HEMATOPOIETIC SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Bone Marrow | + + + + + | 5 |
__________________________________________________________________________|____________|
Lymph Node | + | 1 |
__________________________________________________________________________|____________|
Lymph Node, Mandibular | + + + + + | 5 |
__________________________________________________________________________|____________|
Lymph Node, Mesenteric | + + + + + | 5 |
__________________________________________________________________________|____________|
Spleen | + + + + + | 5 |
__________________________________________________________________________________________________________________________________
* : Total animals with tissue examined microscopically; total animals with tumor
+ : Tissue examined microscopically M : Missing tissue
X : Lesion present A : Autolysis precludes evaluation
I : Insufficient tissue BLANK : Not examined microscopically
NTP Experiment-Test: 05187-09 NEOPLASMS BY INDIVIDUAL ANIMAL Report: PEIRPT04
Study Type: CHRONIC METHYLEUGENOL Date: 07/20/98
Route: GAVAGE Time: 08:39:31
__________________________________________________________________________________________________________________________________
| 1| 1| 1| 1| 1| | |
DAY ON TEST | 8| 8| 8| 8| 8| | |
| 4| 4| 4| 4| 4| | |
_____________________________________________________________________________________________________________________| T (*) |
| 0| 0| 0| 0| 0| | O |
FISCHER 344 RATS FEMALE | 0| 0| 0| 0| 0| | T |
ANIMAL ID | 2| 3| 3| 3| 3| | A |
0 MG/KG | 8| 0| 0| 1| 3| | L |
| 6| 0| 2| 3| 0| | |
__________________________________________________________________________________________________________________________________
HEMATOPOIETIC SYSTEM - cont | | |
| | |
__________________________________________________________________________|____________|
Thymus | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
INTEGUMENTARY SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Mammary Gland | + + + + + | 5 |
__________________________________________________________________________|____________|
Skin | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
MUSCULOSKELETAL SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Bone | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
NERVOUS SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Brain | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
RESPIRATORY SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Lung | + + + + + | 5 |
__________________________________________________________________________|____________|
Nose | + + + + + | 5 |
__________________________________________________________________________|____________|
Trachea | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
SPECIAL SENSES SYSTEM | | |
| | |
None | | |
_____________________________________________________________________________________________________________________| |
URINARY SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Kidney | + + + + + | 5 |
__________________________________________________________________________|____________|
Urinary Bladder | + + + + + | 5 |
__________________________________________________________________________________________________________________________________
SYSTEMIC LESIONS | | |
__________________________________________________________________________|____________|
Multiple Organs | + + + + + | 5 |
__________________________________________________________________________________________________________________________________
* : Total animals with tissue examined microscopically; total animals with tumor
+ : Tissue examined microscopically M : Missing tissue
X : Lesion present A : Autolysis precludes evaluation
I : Insufficient tissue BLANK : Not examined microscopically
NTP Experiment-Test: 05187-09 NEOPLASMS BY INDIVIDUAL ANIMAL Report: PEIRPT04
Study Type: CHRONIC METHYLEUGENOL Date: 07/20/98
Route: GAVAGE Time: 08:39:31
__________________________________________________________________________________________________________________________________
| 1| 1| 1| 1| 1| | |
DAY ON TEST | 8| 8| 8| 8| 8| | |
| 4| 4| 4| 4| 4| | |
_____________________________________________________________________________________________________________________| T (*) |
| 0| 0| 0| 0| 0| | O |
FISCHER 344 RATS FEMALE | 0| 0| 0| 0| 0| | T |
ANIMAL ID | 4| 4| 4| 5| 5| | A |
300 | 8| 8| 8| 0| 3| | L |
MG/KG | 1| 3| 4| 5| 8| | |
__________________________________________________________________________________________________________________________________
ALIMENTARY SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Esophagus | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Large, Colon | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Large, Rectum | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Large, Cecum | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Small, Duodenum | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Small, Jejunum | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Small, Ileum | + + + + + | 5 |
__________________________________________________________________________|____________|
Liver | + + + + + | 5 |
__________________________________________________________________________|____________|
Pancreas | + + + + + | 5 |
__________________________________________________________________________|____________|
Salivary Glands | + + + + + | 5 |
__________________________________________________________________________|____________|
Stomach, Forestomach | + + + + + | 5 |
__________________________________________________________________________|____________|
Stomach, Glandular | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
CARDIOVASCULAR SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Blood Vessel | + + + + + | 5 |
__________________________________________________________________________|____________|
Heart | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
ENDOCRINE SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Adrenal Cortex | + + + + + | 5 |
__________________________________________________________________________|____________|
Adrenal Medulla | + + + + + | 5 |
__________________________________________________________________________|____________|
Islets, Pancreatic | + + + + + | 5 |
__________________________________________________________________________|____________|
Parathyroid Gland | + M M + + | 3 |
__________________________________________________________________________|____________|
Pituitary Gland | + + + + + | 5 |
__________________________________________________________________________|____________|
Thyroid Gland | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
GENERAL BODY SYSTEM | | |
| | |
None | | |
_____________________________________________________________________________________________________________________| |
GENITAL SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Clitoral Gland | + + + + + | 5 |
__________________________________________________________________________|____________|
Ovary | + + + + + | 5 |
__________________________________________________________________________|____________|
Uterus | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
HEMATOPOIETIC SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Bone Marrow | + + + + + | 5 |
__________________________________________________________________________|____________|
Lymph Node, Mandibular | + + + + + | 5 |
__________________________________________________________________________|____________|
Lymph Node, Mesenteric | + + + + + | 5 |
__________________________________________________________________________|____________|
Spleen | + + + + + | 5 |
__________________________________________________________________________|____________|
Thymus | + + + + + | 5 |
__________________________________________________________________________________________________________________________________
* : Total animals with tissue examined microscopically; total animals with tumor
+ : Tissue examined microscopically M : Missing tissue
X : Lesion present A : Autolysis precludes evaluation
I : Insufficient tissue BLANK : Not examined microscopically
NTP Experiment-Test: 05187-09 NEOPLASMS BY INDIVIDUAL ANIMAL Report: PEIRPT04
Study Type: CHRONIC METHYLEUGENOL Date: 07/20/98
Route: GAVAGE Time: 08:39:31
__________________________________________________________________________________________________________________________________
| 1| 1| 1| 1| 1| | |
DAY ON TEST | 8| 8| 8| 8| 8| | |
| 4| 4| 4| 4| 4| | |
_____________________________________________________________________________________________________________________| T (*) |
| 0| 0| 0| 0| 0| | O |
FISCHER 344 RATS FEMALE | 0| 0| 0| 0| 0| | T |
ANIMAL ID | 4| 4| 4| 5| 5| | A |
300 | 8| 8| 8| 0| 3| | L |
MG/KG | 1| 3| 4| 5| 8| | |
__________________________________________________________________________________________________________________________________
HEMATOPOIETIC SYSTEM - cont | | |
| | |
_____________________________________________________________________________________________________________________| |
INTEGUMENTARY SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Mammary Gland | + + + + + | 5 |
__________________________________________________________________________|____________|
Skin | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
MUSCULOSKELETAL SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Bone | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
NERVOUS SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Brain | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
RESPIRATORY SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Lung | + + + + + | 5 |
__________________________________________________________________________|____________|
Nose | + + + + + | 5 |
__________________________________________________________________________|____________|
Trachea | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
SPECIAL SENSES SYSTEM | | |
| | |
None | | |
_____________________________________________________________________________________________________________________| |
URINARY SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Kidney | + + + + + | 5 |
__________________________________________________________________________|____________|
Urinary Bladder | + + + + + | 5 |
__________________________________________________________________________________________________________________________________
SYSTEMIC LESIONS | | |
__________________________________________________________________________|____________|
Multiple Organs | + + + + + | 5 |
__________________________________________________________________________________________________________________________________
* : Total animals with tissue examined microscopically; total animals with tumor
+ : Tissue examined microscopically M : Missing tissue
X : Lesion present A : Autolysis precludes evaluation
I : Insufficient tissue BLANK : Not examined microscopically
NTP Experiment-Test: 05187-09 NEOPLASMS BY INDIVIDUAL ANIMAL Report: PEIRPT04
Study Type: CHRONIC METHYLEUGENOL Date: 07/20/98
Route: GAVAGE Time: 08:39:31
__________________________________________________________________________________________________________________________________
| 1| 1| 1| 1| 1| | |
DAY ON TEST | 8| 8| 8| 8| 8| | |
| 4| 4| 4| 4| 4| | |
_____________________________________________________________________________________________________________________| T (*) |
| 0| 0| 0| 0| 0| | O |
FISCHER 344 RATS MALE | 0| 0| 0| 0| 0| | T |
ANIMAL ID | 0| 0| 0| 0| 0| | A |
0 MG/KG | 3| 3| 3| 3| 5| | L |
| 3| 5| 7| 8| 8| | |
__________________________________________________________________________________________________________________________________
ALIMENTARY SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Esophagus | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Large, Colon | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Large, Rectum | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Large, Cecum | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Small, Duodenum | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Small, Jejunum | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Small, Ileum | + + + + + | 5 |
__________________________________________________________________________|____________|
Liver | + + + + + | 5 |
__________________________________________________________________________|____________|
Pancreas | + + + + + | 5 |
__________________________________________________________________________|____________|
Salivary Glands | + + + + + | 5 |
__________________________________________________________________________|____________|
Stomach, Forestomach | + + + + + | 5 |
__________________________________________________________________________|____________|
Stomach, Glandular | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
CARDIOVASCULAR SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Blood Vessel | + + + + + | 5 |
__________________________________________________________________________|____________|
Heart | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
ENDOCRINE SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Adrenal Cortex | + + + + + | 5 |
__________________________________________________________________________|____________|
Adrenal Medulla | + + + + + | 5 |
__________________________________________________________________________|____________|
Islets, Pancreatic | + + + + + | 5 |
__________________________________________________________________________|____________|
Parathyroid Gland | + + + + + | 5 |
__________________________________________________________________________|____________|
Pituitary Gland | + + + + + | 5 |
__________________________________________________________________________|____________|
Thyroid Gland | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
GENERAL BODY SYSTEM | | |
| | |
None | | |
_____________________________________________________________________________________________________________________| |
GENITAL SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Epididymis | + + + + + | 5 |
__________________________________________________________________________|____________|
Preputial Gland | + + + + + | 5 |
__________________________________________________________________________|____________|
Prostate | + + + + + | 5 |
__________________________________________________________________________|____________|
Seminal Vesicle | + + + + + | 5 |
__________________________________________________________________________|____________|
Testes | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
HEMATOPOIETIC SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Bone Marrow | + + + + + | 5 |
__________________________________________________________________________|____________|
Lymph Node, Mandibular | + + + + + | 5 |
__________________________________________________________________________|____________|
Lymph Node, Mesenteric | + + + + + | 5 |
__________________________________________________________________________________________________________________________________
* : Total animals with tissue examined microscopically; total animals with tumor
+ : Tissue examined microscopically M : Missing tissue
X : Lesion present A : Autolysis precludes evaluation
I : Insufficient tissue BLANK : Not examined microscopically
NTP Experiment-Test: 05187-09 NEOPLASMS BY INDIVIDUAL ANIMAL Report: PEIRPT04
Study Type: CHRONIC METHYLEUGENOL Date: 07/20/98
Route: GAVAGE Time: 08:39:31
__________________________________________________________________________________________________________________________________
| 1| 1| 1| 1| 1| | |
DAY ON TEST | 8| 8| 8| 8| 8| | |
| 4| 4| 4| 4| 4| | |
_____________________________________________________________________________________________________________________| T (*) |
| 0| 0| 0| 0| 0| | O |
FISCHER 344 RATS MALE | 0| 0| 0| 0| 0| | T |
ANIMAL ID | 0| 0| 0| 0| 0| | A |
0 MG/KG | 3| 3| 3| 3| 5| | L |
| 3| 5| 7| 8| 8| | |
__________________________________________________________________________________________________________________________________
HEMATOPOIETIC SYSTEM - cont | | |
| | |
__________________________________________________________________________|____________|
Spleen | + + + + + | 5 |
__________________________________________________________________________|____________|
Thymus | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
INTEGUMENTARY SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Mammary Gland | + + + + + | 5 |
__________________________________________________________________________|____________|
Skin | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
MUSCULOSKELETAL SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Bone | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
NERVOUS SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Brain | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
RESPIRATORY SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Lung | + + + + + | 5 |
__________________________________________________________________________|____________|
Nose | + + + + + | 5 |
__________________________________________________________________________|____________|
Trachea | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
SPECIAL SENSES SYSTEM | | |
| | |
None | | |
_____________________________________________________________________________________________________________________| |
URINARY SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Kidney | + + + + + | 5 |
__________________________________________________________________________|____________|
Urinary Bladder | + + + + + | 5 |
__________________________________________________________________________________________________________________________________
SYSTEMIC LESIONS | | |
__________________________________________________________________________|____________|
Multiple Organs | + + + + + | 5 |
__________________________________________________________________________________________________________________________________
* : Total animals with tissue examined microscopically; total animals with tumor
+ : Tissue examined microscopically M : Missing tissue
X : Lesion present A : Autolysis precludes evaluation
I : Insufficient tissue BLANK : Not examined microscopically
NTP Experiment-Test: 05187-09 NEOPLASMS BY INDIVIDUAL ANIMAL Report: PEIRPT04
Study Type: CHRONIC METHYLEUGENOL Date: 07/20/98
Route: GAVAGE Time: 08:39:31
__________________________________________________________________________________________________________________________________
| 1| 1| 1| 1| 1| | |
DAY ON TEST | 8| 8| 8| 8| 8| | |
| 4| 4| 4| 4| 4| | |
_____________________________________________________________________________________________________________________| T (*) |
| 0| 0| 0| 0| 0| | O |
FISCHER 344 RATS MALE | 0| 0| 0| 0| 0| | T |
ANIMAL ID | 2| 2| 2| 2| 2| | A |
300 | 1| 2| 4| 6| 6| | L |
MG/KG | 2| 9| 3| 4| 8| | |
__________________________________________________________________________________________________________________________________
ALIMENTARY SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Esophagus | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Large, Colon | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Large, Rectum | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Large, Cecum | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Small, Duodenum | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Small, Jejunum | + + + + + | 5 |
__________________________________________________________________________|____________|
Intestine Small, Ileum | + + + + + | 5 |
__________________________________________________________________________|____________|
Liver | + + + + + | 5 |
__________________________________________________________________________|____________|
Pancreas | + + + + + | 5 |
__________________________________________________________________________|____________|
Salivary Glands | + + + + + | 5 |
__________________________________________________________________________|____________|
Stomach, Forestomach | + + + + + | 5 |
__________________________________________________________________________|____________|
Stomach, Glandular | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
CARDIOVASCULAR SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Blood Vessel | + + + + + | 5 |
__________________________________________________________________________|____________|
Heart | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
ENDOCRINE SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Adrenal Cortex | + + + + + | 5 |
__________________________________________________________________________|____________|
Adrenal Medulla | + + + + + | 5 |
__________________________________________________________________________|____________|
Islets, Pancreatic | + + + + + | 5 |
__________________________________________________________________________|____________|
Parathyroid Gland | + + + + + | 5 |
__________________________________________________________________________|____________|
Pituitary Gland | + + + + + | 5 |
__________________________________________________________________________|____________|
Thyroid Gland | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
GENERAL BODY SYSTEM | | |
| | |
None | | |
_____________________________________________________________________________________________________________________| |
GENITAL SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Epididymis | + + + + + | 5 |
__________________________________________________________________________|____________|
Preputial Gland | + + + + + | 5 |
__________________________________________________________________________|____________|
Prostate | + + + + + | 5 |
__________________________________________________________________________|____________|
Seminal Vesicle | + + + + + | 5 |
__________________________________________________________________________|____________|
Testes | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
HEMATOPOIETIC SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Bone Marrow | + + + + + | 5 |
__________________________________________________________________________|____________|
Lymph Node, Mandibular | + + + + + | 5 |
__________________________________________________________________________|____________|
Lymph Node, Mesenteric | + + + + + | 5 |
__________________________________________________________________________________________________________________________________
* : Total animals with tissue examined microscopically; total animals with tumor
+ : Tissue examined microscopically M : Missing tissue
X : Lesion present A : Autolysis precludes evaluation
I : Insufficient tissue BLANK : Not examined microscopically
NTP Experiment-Test: 05187-09 NEOPLASMS BY INDIVIDUAL ANIMAL Report: PEIRPT04
Study Type: CHRONIC METHYLEUGENOL Date: 07/20/98
Route: GAVAGE Time: 08:39:31
__________________________________________________________________________________________________________________________________
| 1| 1| 1| 1| 1| | |
DAY ON TEST | 8| 8| 8| 8| 8| | |
| 4| 4| 4| 4| 4| | |
_____________________________________________________________________________________________________________________| T (*) |
| 0| 0| 0| 0| 0| | O |
FISCHER 344 RATS MALE | 0| 0| 0| 0| 0| | T |
ANIMAL ID | 2| 2| 2| 2| 2| | A |
300 | 1| 2| 4| 6| 6| | L |
MG/KG | 2| 9| 3| 4| 8| | |
__________________________________________________________________________________________________________________________________
HEMATOPOIETIC SYSTEM - cont | | |
| | |
__________________________________________________________________________|____________|
Spleen | + + + + + | 5 |
__________________________________________________________________________|____________|
Thymus | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
INTEGUMENTARY SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Mammary Gland | + + + + + | 5 |
__________________________________________________________________________|____________|
Skin | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
MUSCULOSKELETAL SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Bone | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
NERVOUS SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Brain | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
RESPIRATORY SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Lung | + + + + + | 5 |
__________________________________________________________________________|____________|
Nose | + + + + + | 5 |
__________________________________________________________________________|____________|
Trachea | + + + + + | 5 |
_____________________________________________________________________________________________________________________| |
SPECIAL SENSES SYSTEM | | |
| | |
None | | |
_____________________________________________________________________________________________________________________| |
URINARY SYSTEM | | |
| | |
__________________________________________________________________________|____________|
Kidney | + + + + + | 5 |
__________________________________________________________________________|____________|
Urinary Bladder | + + + + + | 5 |
__________________________________________________________________________________________________________________________________
SYSTEMIC LESIONS | | |
__________________________________________________________________________|____________|
Multiple Organs | + + + + + | 5 |
__________________________________________________________________________________________________________________________________
* : Total animals with tissue examined microscopically; total animals with tumor
+ : Tissue examined microscopically M : Missing tissue
X : Lesion present A : Autolysis precludes evaluation
I : Insufficient tissue BLANK : Not examined microscopically
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