TDMS Study 05205-07 Pathology Tables
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: Southern Research Inst P-NITROTOLUENE DATE: 03/13/00
EXPERIMENT: 05205 TEST: 07 TIME: 13:55:08
CAGES FROM 0000 TO LAST CAGE PAGE: 1
TEST TYPE: CHRONIC ROUTE: DOSED FEED NTP: C62537D
CONT: N01-ES-55393 CAS: 99-99-0
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REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: SOUTHERN RESEARCH INSTITUTE P-NITROTOLUENE DATE: 03/13/00
EXPERIMENT: 05205 TEST: 07 TIME: 14:05:09
SPECIES: RATS, FISCHER 344
TEST TYPE: TWO YEAR ROUTE: DOSED FEED NTP: 62537D
CONT: N01-ES-55393 CAS: 99-99-0
MEAN BODY WEIGHTS AND SURVIVAL OF MALE RATS IN THE
TWO YEAR DOSED FEED STUDY OF P-NITROTOLUENE
==========================================================================================================
WEEK 0 PPM 1250 PPM 2500 PPM 5000 PPM
---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
=========================================================================================================
B 102.4 50 102.2 99.8 50 102.8 100.4 50 101.2 98.8 50
1 102.4 50 102.2 99.8 50 102.8 100.4 50 101.2 98.8 50
4 205.9 50 200.4 97.3 50 196.4 95.4 50 180.6 87.7 50
8 281.5 50 273.1 97.0 50 269.6 95.8 50 246.1 87.4 50
12 324.0 50 318.8 98.4 50 309.9 95.6 50 282.5 87.2 50
16 352.2 50 342.0 97.1 50 336.4 95.5 50 303.4 86.1 50
20 377.2 50 364.8 96.7 50 359.1 95.2 50 321.5 85.2 50
24 390.4 50 380.8 97.5 50 368.3 94.3 50 334.7 85.7 50
28 404.5 50 391.9 96.9 50 384.4 95.0 50 342.8 84.7 50
32 421.3 50 404.3 96.0 50 393.6 93.4 50 352.4 83.6 50
36 422.4 50 410.3 97.1 50 402.7 95.3 50 361.8 85.7 50
40 425.7 50 413.7 97.2 50 405.1 95.2 50 361.3 84.9 50
44 433.0 50 422.1 97.5 50 410.4 94.8 50 368.4 85.1 50
48 436.0 50 425.8 97.7 50 417.9 95.8 50 370.1 84.9 50
52 438.0 50 426.8 97.4 50 418.6 95.6 50 373.7 85.3 50
56 434.9 49 423.4 97.4 50 415.0 95.4 50 373.3 85.8 50
60 437.0 49 429.9 98.4 50 419.4 96.0 50 377.9 86.5 50
64 439.5 49 431.5 98.2 50 424.5 96.6 50 381.0 86.7 50
68 439.2 49 431.4 98.2 50 427.2 97.3 50 380.8 86.7 50
72 437.5 49 427.9 97.8 49 424.5 97.0 50 384.9 88.0 48
76 440.4 48 436.7 99.2 47 432.0 98.1 49 389.9 88.5 48
80 443.8 48 436.5 98.4 47 432.6 97.5 49 389.6 87.8 48
84 434.1 48 433.6 99.9 46 429.5 98.9 49 386.8 89.1 48
88 431.5 45 428.0 99.2 44 423.7 98.2 49 384.7 89.2 46
92 424.7 43 426.3 100.4 41 416.9 98.2 47 381.2 89.8 45
96 419.4 41 419.5 100.0 40 412.1 98.3 46 379.9 90.6 45
100 410.4 37 415.4 101.2 39 408.9 99.6 42 373.7 91.1 41
104 402.1 33 409.0 101.7 39 402.0 100.0 41 366.0 91.0 40
TERM. SAC. 31 38 38 40
==========================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.
MEAN BODY WEIGHTS AND SURVIVAL OF FEMALE RATS IN THE
TWO YEAR DOSED FEED STUDY OF P-NITROTOLUENE
==========================================================================================================
WEEK 0 PPM 1250 PPM 2500 PPM 5000 PPM
---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
=========================================================================================================
B 91.4 50 90.2 98.7 50 91.3 99.9 50 92.0 100.7 50
1 91.4 50 90.2 98.7 50 91.3 99.9 50 92.0 100.7 50
4 143.6 50 140.5 97.8 50 140.4 97.8 50 134.3 93.5 50
8 167.9 50 165.6 98.6 50 163.7 97.5 50 155.5 92.6 50
12 181.9 50 179.0 98.4 50 176.3 96.9 50 166.6 91.6 50
16 192.3 50 187.7 97.6 50 184.9 96.2 50 173.2 90.1 50
20 197.5 50 194.1 98.3 50 191.3 96.9 50 181.8 92.1 50
24 203.9 50 200.4 98.3 50 196.3 96.3 50 184.6 90.5 50
28 210.9 50 206.5 97.9 50 201.4 95.5 50 188.9 89.6 50
32 219.6 50 208.7 95.0 50 206.2 93.9 50 193.6 88.2 50
36 222.6 50 215.6 96.9 50 212.1 95.3 50 198.2 89.0 50
40 224.2 50 215.7 96.2 50 212.8 94.9 50 195.6 87.2 50
44 231.6 50 221.5 95.6 50 215.9 93.2 50 198.2 85.6 50
48 234.0 50 224.4 95.9 50 217.6 93.0 50 197.9 84.6 50
52 235.7 50 227.0 96.3 50 219.7 93.2 50 200.7 85.2 50
56 243.4 49 231.0 94.9 49 224.5 92.2 49 200.7 82.5 50
60 249.6 49 235.6 94.4 49 225.8 90.5 49 201.6 80.8 50
64 257.9 49 239.4 92.8 49 231.9 89.9 49 202.8 78.6 50
68 263.2 49 249.0 94.6 49 237.9 90.4 49 205.5 78.1 50
72 270.3 48 253.0 93.6 49 241.0 89.2 49 207.0 76.6 50
76 276.6 47 260.4 94.1 48 249.0 90.0 49 207.8 75.1 50
80 284.6 47 267.4 94.0 48 257.4 90.4 49 212.7 74.7 49
84 288.3 46 268.2 93.0 47 261.0 90.5 49 211.5 73.4 49
88 293.1 45 268.6 91.6 47 261.6 89.3 49 210.2 71.7 49
92 295.2 45 271.7 92.0 44 261.6 88.6 47 211.6 71.7 47
96 293.1 44 269.2 91.8 43 261.8 89.3 46 210.8 71.9 47
100 293.0 41 272.1 92.9 42 266.2 90.9 40 211.9 72.3 44
104 293.8 39 271.5 92.4 38 267.2 90.9 39 209.8 71.4 42
TERM. SAC. 39 37 39 41
==========================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.