TDMS Study 05211-05 Pathology Tables
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41 LAB: Southern Research Inst EMODIN DATE: 03/26/99 EXPERIMENT: 05211 TEST: 05 TIME: 08:30:45 CAGES FROM 0000 TO LAST CAGE PAGE: 1 TEST TYPE: CHRONIC ROUTE: DOSED FEED NTP: C62408 CONT: NO1-ES-85216 CAS: 518-82-1 ------------------------------------------------------------------------------------------------------------------------------------ REASONS FOR REMOVAL: ALL REMOVAL DATE RANGE: ALL TREATMENT GROUPS: INCLUDE ALL NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41 LAB: SOUTHERN RESEARCH INSTITUTE EMODIN DATE: 03/26/99 EXPERIMENT: 05211 TEST: 05 TIME: 8:41:54 TEST TYPE: TWO YEAR ROUTE: DOSED FEED NTP: C62408 CONT: NO1-ES-85216 CAS: 518-82-1 MEAN BODY WEIGHTS AND SURVIVAL OF MALE RATS IN THE TWO YEAR DOSED FEED STUDY OF EMODIN ========================================================================================================== WEEK 0 PPM 280 PPM 830 PPM 2500 PPM ---------------- ---------------- ---------------- ---------------- AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. (GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) ========================================================================================================= B 138.5 60 134.5 97.1 60 134.2 96.9 60 133.0 96.0 60 1 138.5 60 134.5 97.1 60 134.2 96.9 60 133.0 96.0 60 2 178.4 60 174.5 97.8 60 171.1 95.9 60 160.3 89.9 60 3 214.1 60 208.3 97.3 60 204.0 95.3 60 192.1 89.7 60 4 242.0 60 234.7 97.0 60 230.1 95.1 60 211.4 87.4 60 5 263.9 60 259.9 98.5 60 252.5 95.7 60 236.4 89.6 60 6 282.6 60 277.6 98.2 60 269.4 95.3 60 253.4 89.7 60 7 299.4 60 293.8 98.1 60 286.2 95.6 60 268.7 89.7 60 8 313.1 60 307.3 98.1 60 298.1 95.2 60 277.8 88.7 60 9 325.0 60 319.3 98.2 60 310.4 95.5 60 290.6 89.4 60 10 328.1 60 323.2 98.5 60 321.1 97.9 60 302.3 92.1 60 11 342.2 60 337.7 98.7 60 329.5 96.3 60 314.2 91.8 60 12 351.5 60 345.4 98.3 60 335.6 95.5 60 318.9 90.7 60 13 358.8 60 356.1 99.2 60 343.5 95.7 60 330.0 92.0 60 17 385.9 60 382.0 99.0 60 372.6 96.6 60 355.6 92.1 60 21 404.7 59 399.9 98.8 60 389.6 96.3 60 369.4 91.3 60 25 419.6 59 416.0 99.1 60 404.1 96.3 60 387.1 92.3 60 29 437.5 49 (I) 430.6 98.4 50 (I) 423.2 96.7 50 (I) 398.2 91.0 50 (I) 33 448.0 48 442.8 98.8 50 433.5 96.8 50 412.3 92.0 50 37 460.5 48 457.1 99.3 50 445.2 96.7 50 426.8 92.7 50 41 463.6 48 456.8 98.5 50 448.6 96.8 50 431.3 93.0 49 45 466.5 47 464.9 99.7 50 457.5 98.1 50 436.2 93.5 49 49 470.6 47 468.2 99.5 50 459.5 97.6 50 439.8 93.5 49 53 472.5 47 469.0 99.3 50 458.2 97.0 50 440.7 93.3 49 57 473.5 47 471.8 99.6 50 463.5 97.9 48 443.6 93.7 49 61 472.4 46 467.9 99.0 50 459.3 97.2 48 440.2 93.2 49 65 470.6 46 464.5 98.7 50 458.1 97.3 48 439.9 93.5 49 69 471.6 45 465.1 98.6 48 458.5 97.2 48 440.4 93.4 48 73 470.7 45 464.2 98.6 47 456.9 97.1 47 443.1 94.1 47 77 471.3 44 464.0 98.5 45 456.6 96.9 45 441.6 93.7 47 81 471.7 44 462.0 97.9 42 453.6 96.2 44 442.6 93.8 46 85 465.4 44 460.1 98.9 41 456.3 98.0 43 442.5 95.1 46 89 459.4 38 449.4 97.8 37 444.2 96.7 38 434.4 94.6 39 93 456.1 37 444.6 97.5 32 430.9 94.5 33 430.0 94.3 38 97 452.0 36 432.4 95.7 31 429.4 95.0 30 427.4 94.6 35 101 448.8 33 426.9 95.1 26 420.4 93.7 25 417.2 93.0 34 TERM. SAC. 30 21 21 30 ========================================================================================================== (A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE. (B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT. (I) INTERIM SACRIFICE OCCURRED IN THIS WEEK. (*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK IS LESS THAN THE NUMBER OF ANIMALS SURVIVING. MEAN BODY WEIGHTS AND SURVIVAL OF FEMALE RATS IN THE TWO YEAR DOSED FEED STUDY OF EMODIN ========================================================================================================== WEEK 0 PPM 280 PPM 830 PPM 2500 PPM ---------------- ---------------- ---------------- ---------------- AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. (GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) ========================================================================================================= B 110.8 60 109.4 98.7 60 109.0 98.4 60 107.9 97.4 60 1 110.8 60 109.4 98.7 60 109.0 98.4 60 107.9 97.4 60 2 131.1 60 129.1 98.5 60 127.7 97.4 60 123.9 94.5 60 3 144.5 60 140.7 97.4 60 139.2 96.3 60 134.4 93.0 60 4 152.5 60 150.2 98.5 60 147.8 96.9 60 141.7 92.9 60 5 163.2 60 161.4 98.9 60 157.2 96.3 60 151.7 93.0 60 6 168.9 60 165.4 97.9 60 162.7 96.3 60 156.8 92.8 60 7 176.0 60 172.5 98.0 60 170.2 96.7 60 164.3 93.4 60 8 180.3 60 175.8 97.5 60 174.8 96.9 60 169.5 94.0 60 9 182.8 60 179.9 98.4 60 177.4 97.0 60 173.2 94.7 60 10 185.2 60 182.5 98.5 60 179.9 97.1 60 176.0 95.0 60 11 189.5 60 187.2 98.8 60 184.7 97.5 60 180.2 95.1 60 12 191.8 60 189.5 98.8 60 187.2 97.6 60 184.7 96.3 60 13 194.8 60 191.9 98.5 60 188.6 96.8 60 185.9 95.4 60 17 204.7 60 203.2 99.3 60 198.7 97.1 60 197.8 96.6 60 21 211.3 60 208.7 98.8 60 205.4 97.2 60 202.0 95.6 60 25 219.3 60 214.0 97.6 60 210.9 96.2 60 209.2 95.4 60 29 226.0 50 (I) 222.2 98.3 50 (I) 217.3 96.2 50 (I) 216.7 95.9 50 (I) 33 234.6 50 228.3 97.3 50 226.2 96.4 50 221.7 94.5 50 37 240.9 50 232.8 96.6 50 230.0 95.5 49 224.3 93.1 50 41 247.3 50 239.6 96.9 50 237.2 95.9 49 232.4 94.0 50 45 254.9 50 247.2 97.0 50 242.6 95.2 49 237.1 93.0 50 49 264.5 50 253.1 95.7 50 250.0 94.5 49 245.0 92.6 50 53 268.4 50 255.9 95.3 50 253.2 94.3 49 247.3 92.1 49 57 273.7 50 262.8 96.0 50 260.1 95.0 49 253.4 92.6 49 61 282.2 50 268.6 95.2 49 267.9 94.9 49 259.9 92.1 49 65 292.2 49 277.3 94.9 49 278.1 95.2 49 272.2 93.2 49 69 301.4 49 286.4 95.0 49 287.1 95.3 49 279.1 92.6 49 73 308.1 48 293.3 95.2 49 294.0 95.4 49 289.4 93.9 49 77 319.0 47 302.1 94.7 49 299.9 94.0 48 296.3 92.9 48 81 323.9 46 302.5 93.4 49 308.1 95.1 47 295.8 91.3 48 85 330.6 46 315.9 95.6 47 314.2 95.0 47 303.7 91.9 47 89 332.9 44 316.9 95.2 45 318.4 95.6 45 301.8 90.7 42 93 330.0 40 318.7 96.6 43 316.8 96.0 45 307.6 93.2 41 97 336.3 39 326.1 97.0 41 319.7 95.1 42 310.1 92.2 38 101 335.9 37 330.5 98.4 40 330.5 98.4 39 314.2 93.5 35 TERM. SAC. 33 39 35 34 ========================================================================================================== (A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE. (B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT. (I) INTERIM SACRIFICE OCCURRED IN THIS WEEK. (*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.