TDMS Study 05211-06 Pathology Tables
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: Southern Research Inst EMODIN DATE: 12/02/98
EXPERIMENT: 05211 TEST: 06 TIME: 10:09:27
CAGES FROM 0000 TO LAST CAGE PAGE: 1
TEST TYPE: CHRONIC ROUTE: DOSED FEED NTP: C62408
CONT: NO1-ES-85216 CAS: 518-82-1
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REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: SOUTHERN RESEARCH INSTITUTE EMODIN DATE: 12/02/98
EXPERIMENT: 05211 TEST: 06 TIME: 10:22:21
TEST TYPE: TWO YEAR ROUTE: DOSED FEED NTP: C62408
CONT: NO1-ES-85216 CAS: 518-82-1
MEAN BODY WEIGHTS AND SURVIVAL OF MALE MICE IN THE
TWO YEAR DOSED FEED STUDY OF EMODIN
==========================================================================================================
WEEK 0 PPM 160 PPM 312 PPM 625 PPM
---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
=========================================================================================================
B 23.8 60 23.8 100.0 60 24.0 100.8 60 23.5 98.7 60
1 23.8 60 23.8 100.0 60 24.0 100.8 60 23.5 98.7 60
2 25.7 60 25.5 99.2 60 25.7 100.0 60 25.5 99.2 60
3 27.1 60 26.9 99.3 60 26.8 98.9 60 26.9 99.3 60
4 27.8 60 27.4 98.6 60 27.6 99.3 60 27.5 98.9 60
5 28.7 60 28.3 98.6 60 28.6 99.7 60 28.5 99.3 60
6 29.6 60 29.4 99.3 60 29.5 99.7 60 29.3 99.0 60
7 30.3 60 30.2 99.7 60 30.6 101.0 60 30.2 99.7 60
8 31.4 60 31.2 99.4 60 31.3 99.7 60 31.2 99.4 60
9 31.7 60 31.3 98.7 60 31.6 99.7 60 31.4 99.1 60
10 32.4 60 32.3 99.7 60 32.4 100.0 60 32.4 100.0 60
11 33.7 60 33.3 98.8 60 33.5 99.4 60 33.5 99.4 60
12 34.3 60 33.8 98.5 60 34.0 99.1 60 33.9 98.8 60
13 34.9 60 34.4 98.6 60 34.4 98.6 60 34.6 99.1 60
17 37.7 60 37.3 98.9 60 37.5 99.5 60 37.8 100.3 60
21 40.5 60 40.1 99.0 60 40.5 100.0 60 40.3 99.5 60
25 41.7 60 41.2 98.8 60 41.5 99.5 60 41.4 99.3 60
29 44.6 60 43.4 97.3 60 43.5 97.5 60 43.4 97.3 60
33 46.2 60 44.7 96.8 60 45.3 98.1 60 45.0 97.4 60
37 48.0 60 47.0 97.9 60 47.2 98.3 60 46.8 97.5 60
41 48.4 60 47.8 98.8 60 47.9 99.0 60 47.3 97.7 60
45 48.9 60 48.5 99.2 60 48.5 99.2 59* 48.2 98.6 59
49 49.5 60 49.0 99.0 60 49.0 99.0 60 48.8 98.6 59
53 49.2 60 (I) 48.8 99.2 60 (I) 48.5 98.6 60 (I) 48.2 98.0 59 (I)
57 49.9 50 48.7 97.6 50 49.1 98.4 50 48.6 97.4 49
61 50.2 50 49.2 98.0 50 50.0 99.6 50 49.3 98.2 49
65 50.4 50 49.3 97.8 49 50.0 99.2 50 49.4 98.0 49
69 50.5 50 49.7 98.4 48 50.0 99.0 50 49.8 98.6 49
73 51.1 50 50.2 98.2 48 50.1 98.0 49 49.8 97.5 49
77 50.2 50 49.1 97.8 48 49.2 98.0 49 49.0 97.6 49
81 50.0 49 48.7 97.4 47 49.3 98.6 48 49.0 98.0 49
85 50.3 49 49.3 98.0 47 50.6 100.6 45 49.6 98.6 49
89 49.9 49 48.6 97.4 47 49.8 99.8 45 49.2 98.6 48
93 50.6 45 49.7 98.2 42 50.0 98.8 44 49.4 97.6 46
97 50.1 44 49.2 98.2 42 49.5 98.8 44 48.7 97.2 46
101 49.6 42 48.7 98.2 39 48.8 98.4 42 48.3 97.4 45
TERM. SAC. 41 37 40 43
==========================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.
MEAN BODY WEIGHTS AND SURVIVAL OF FEMALE MICE IN THE
TWO YEAR DOSED FEED STUDY OF EMODIN
==========================================================================================================
WEEK 0 PPM 312 PPM 625 PPM 1250 PPM
---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
=========================================================================================================
B 17.5 60 17.8 101.7 60 17.3 98.9 60 18.0 102.9 60
1 18.5 60 18.5 100.0 60 18.5 100.0 60 18.6 100.5 60
2 20.7 60 20.4 98.6 60 20.5 99.0 60 20.3 98.1 60
3 20.9 60 20.0 95.7 60 20.4 97.6 60 19.8 94.7 60
4 19.6 60 21.4 109.2 60 20.7 105.6 60 21.7 110.7 60
5 21.2 60 20.7 97.6 60 21.1 99.5 60 21.6 101.9 60
6 22.8 60 22.6 99.1 60 23.1 101.3 60 22.7 99.6 60
7 23.6 60 23.5 99.6 60 23.5 99.6 60 23.5 99.6 60
8 23.0 60 23.3 101.3 60 23.2 100.9 60 24.1 104.8 60
9 23.5 60 24.2 103.0 60 23.4 99.6 60 24.6 104.7 60
10 25.7 60 25.4 98.8 60 25.6 99.6 60 25.8 100.4 60
11 25.6 60 25.1 98.0 60 25.5 99.6 60 25.9 101.2 60
12 26.3 60 26.4 100.4 60 26.4 100.4 60 26.9 102.3 60
16 29.9 60 29.9 100.0 60 30.6 102.3 59 30.6 102.3 60
20 31.6 60 32.6 103.2 60 33.2 105.1 59 32.6 103.2 60
24 34.5 60 34.9 101.2 60 35.1 101.7 59 36.0 104.3 60
28 36.8 60 36.9 100.3 60 37.4 101.6 59 37.4 101.6 60
32 39.4 60 39.0 99.0 60 39.8 101.0 59 39.2 99.5 60
36 41.6 60 41.5 99.8 60 42.2 101.4 59 41.8 100.5 60
40 44.7 60 43.6 97.5 60 44.6 99.8 59 43.6 97.5 60
44 45.5 60 45.3 99.6 60 46.5 102.2 59 45.2 99.3 60
48 46.2 60 46.3 100.2 60 46.7 101.1 59 45.7 98.9 60
52 48.5 60 47.2 97.3 60 48.1 99.2 59 47.8 98.6 60
56 49.8 50 (I) 48.6 97.6 50 (I) 50.3 101.0 49 (I) 49.3 99.0 50 (I)
60 50.7 50 50.9 100.4 49 51.4 101.4 49 51.0 100.6 50
64 51.6 50 52.3 101.4 49 52.5 101.7 49 52.0 100.8 49
68 53.3 50 54.3 101.9 48 54.7 102.6 48 53.8 100.9 49
72 56.1 49 55.7 99.3 47 55.9 99.6 48 54.8 97.7 49
76 55.6 49 56.0 100.7 46 55.7 100.2 48 55.2 99.3 47
80 56.5 47 56.3 99.6 45 56.3 99.6 48 55.6 98.4 47
84 58.0 47 57.5 99.1 45 57.3 98.8 48 56.5 97.4 47
88 58.7 43 57.5 98.0 45 58.2 99.1 48 56.2 95.7 45
92 57.2 42 57.1 99.8 44 57.3 100.2 47 55.5 97.0 45
96 58.5 41 58.1 99.3 43 58.1 99.3 46 55.3 94.5 43
100 57.7 39 57.0 98.8 42 56.0 97.1 44 54.2 93.9 38
TERM. SAC. 37 39 42 36
==========================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.