https://ntp.niehs.nih.gov/go/5221

TDMS Study 05704-03 Pathology Tables

NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97
Route: GAVAGE                                                                                                     Time: 07:49:44
       Facility:  International Research and Development Corp.
       Chemical CAS #:  000108463
       Lock Date:  None
       Cage Range:  All
       Reasons For Removal:    All
       Removal Date Range:     All
       Treatment Groups:       Include All
                                                              Page   1
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 5| 7| 7| 7| 4| 6| 7| 6| 7| 7| 7| 5| 4| 7| 6| 7| 7| 7| 5| 7| 7| 7| 4| 7| 5|             
                             DAY ON TEST   | 4| 2| 3| 2| 5| 2| 3| 9| 3| 3| 2| 2| 5| 3| 9| 1| 3| 2| 7| 2| 3| 3| 5| 3| 6|             
                                           | 5| 9| 1| 9| 7| 3| 0| 5| 0| 0| 9| 1| 7| 0| 3| 7| 0| 9| 9| 9| 1| 1| 7| 1| 1|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    VEHICLE/                               | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    CONTROL                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     I  +|             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Parasite Metazoan                    |                X                                X                    X   |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Parasite Metazoan                    | X                          X                    X                        |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Parasite Metazoan                    |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Angiectasis, Focal                   |          3                                2                              |             
      Basophilic Focus                     | X                                      X                             X   |             
      Basophilic Focus, Multiple           |    X  X  X        X     X  X  X  X        X     X  X     X  X  X        X|             
      Clear Cell Focus                     |    X              X           X                             X            |             
      Clear Cell Focus, Multiple           |                                                       X                  |             
      Congestion, Focal                    |                                                                          |             
      Hematocyst                           |                                                                          |             
      Hepatodiaphragmatic Nodule           |                   X           X                                          |             
      Hepatodiaphragmatic Nodule, Multiple |          X                                         X                     |             
      Hyperplasia, Focal                   |                                                                          |             
      Inflammation, Chronic, Focal         | 1  1  1  2        3  1  2     3  1     2  2     2        2  2  1     3   |             
      Necrosis, Focal                      |                                                                          |             
      Bile Duct, Hyperplasia               |    2     2        2     1  4  2              4  1  1     1  1  1         |             
      Centrilobular, Fatty Change          |                      3                       3                           |             
      Serosa, Fibrosis, Focal              |                                        1                                 |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                              +                           |             
      Fat, Necrosis                        |                                              4                           |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Atrophy, Focal                       |                   1  2     2           2        1  2     1               |             
      Focal Cellular Change                |                                              X                           |             
      Hyperplasia, Focal                   |                         2                                                |             
                                            __________________________________________________________________________|             
   Pharynx                                 |                                                                          |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Inflammation, Chronic                |       2                                                                  |             
      Duct, Ectasia, Focal                 |       2                                                                  |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Hyperplasia, Diffuse, Squamous       |                                                                          |             
      Inflammation, Chronic, Diffuse       |                                                                          |             
      Ulcer                                |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page   2                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 5| 7| 7| 7| 4| 6| 7| 6| 7| 7| 7| 5| 4| 7| 6| 7| 7| 7| 5| 7| 7| 7| 4| 7| 5|             
                             DAY ON TEST   | 4| 2| 3| 2| 5| 2| 3| 9| 3| 3| 2| 2| 5| 3| 9| 1| 3| 2| 7| 2| 3| 3| 5| 3| 6|             
                                           | 5| 9| 1| 9| 7| 3| 0| 5| 0| 0| 9| 1| 7| 0| 3| 7| 0| 9| 9| 9| 1| 1| 7| 1| 1|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    VEHICLE/                               | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    CONTROL                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
      Erosion                              |                                                       1                  |             
                                            __________________________________________________________________________|             
   Tooth                                   |                         +                                                |             
      Gingiva, Foreign Body                |                         3                                                |             
      Gingiva, Hyperplasia, Focal, Squamous|                         3                                                |             
      Gingiva, Inflammation, Chronic, Focal|                         3                                                |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Inflammation, Chronic, Focal         |    2     2        2     2     2        2  1                    2     2   |             
      Endocardium, Hemorrhage, Focal       |                      2                                                   |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Angiectasis                          |          2        2  2                                                   |             
      Cyst                                 |                                              X                           |             
      Cytoplasmic Alteration, Focal        |          1                                                               |             
      Degeneration, Ballooning, Focal      |                                                                      4   |             
      Degeneration, Fatty, Focal           |    2  1                                   3  3        2  2               |             
      Hematocyst                           |                                                                          |             
      Hyperplasia, Focal                   |       2           2           2           2              2               |             
      Hypertrophy, Focal                   |                      2                    2                              |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +  +     +  +  I  +  +  +  +     +  +  +  +  +  +  +  +  +     M  +|             
      Hyperplasia                          |                         1                    1        1                  |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +  +  +  M     M  +  +  +  +  +  +     +  +  +  +  +  M  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +|             
      Amyloid Deposition                   |                                                                          |             
      Angiectasis                          |                               4                 3        3               |             
      Cyst                                 | X  X  X        X           X  X                                          |             
      Cyst, Multiple                       |          X                                                  X            |             
      Ectasia                              |                            3                                             |             
      Pars Distalis, Angiectasis           |                                                                   2      |             
      Pars Distalis, Hyperplasia, Focal    |    3           2           3  2                          2               |             
      Pars Distalis, Hyperplasia,          |                                                                          |             
          Multifocal                       |                                                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      C-Cell, Hyperplasia, Focal           |                   2           2              3  1                        |             
      Follicular Cell, Metaplasia, Focal,  |                                                                          |             
           Squamous                        |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   3                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 5| 7| 7| 7| 4| 6| 7| 6| 7| 7| 7| 5| 4| 7| 6| 7| 7| 7| 5| 7| 7| 7| 4| 7| 5|             
                             DAY ON TEST   | 4| 2| 3| 2| 5| 2| 3| 9| 3| 3| 2| 2| 5| 3| 9| 1| 3| 2| 7| 2| 3| 3| 5| 3| 6|             
                                           | 5| 9| 1| 9| 7| 3| 0| 5| 0| 0| 9| 1| 7| 0| 3| 7| 0| 9| 9| 9| 1| 1| 7| 1| 1|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    VEHICLE/                               | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    CONTROL                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Clitoral Gland                          | +  +  +  +  +  M  +  +  +  +  +  M     +  +  M  +  +  +  +  +  +     +  +|             
      Dilatation                           |                                                          4               |             
      Hyperplasia, Focal                   |                                                                3     3   |             
      Inflammation, Chronic, Focal         |    2     1                                                     3     2   |             
      Inflammation, Suppurative            |                            4                                             |             
                                            __________________________________________________________________________|             
   Ovary                                   | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +|             
      Cyst                                 |                            X                 X           X               |             
      Corpus Luteum, Necrosis              |                                              4                           |             
      Periovarian Tissue, Necrosis, Focal  |                   4                                                      |             
                                            __________________________________________________________________________|             
   Uterus                                  | +  +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Hyperplasia, Chronic, Cystic         |                                                                2         |             
      Cervix, Fibrosis                     |                                                                          |             
      Serosa, Necrosis                     |                                                                          |             
                                            __________________________________________________________________________|             
   Vagina                                  |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Myelofibrosis, Focal                 |                                              3                           |             
      Erythroid Cell, Proliferation        |                3                                                         |             
      Myeloid Cell, Proliferation          |                                              3                           |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Axillary, Infiltration Cellular,     |                                                                          |             
           Histiocyte                      |                                                                          |             
      Iliac, Hyperplasia, Plasma Cell      |                                                                          |             
      Mandibular, Congestion               |       4                                                                  |             
      Mandibular, Hyperplasia, Plasma Cell |                                                          4               |             
      Mediastinal, Hemorrhage              |                                                                          |             
      Mediastinal, Inflammation,           |                                                                          |             
          Suppurative                      |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Congestion                           |                                                                          |             
      Hemorrhage                           |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Angiectasis                          |                                                                          |             
      Hematopoietic Cell Proliferation     |                3                                      3                 2|             
      Hyperplasia, Lymphoid                |                                                                          |             
      Capsule, Fibrosis                    |                            4                                             |             
                                            __________________________________________________________________________|             
   Thymus                                  | +  +  +  M     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     M  +|             
      Cyst                                 |                                                             X            |             
      Hemorrhage                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page   4                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 5| 7| 7| 7| 4| 6| 7| 6| 7| 7| 7| 5| 4| 7| 6| 7| 7| 7| 5| 7| 7| 7| 4| 7| 5|             
                             DAY ON TEST   | 4| 2| 3| 2| 5| 2| 3| 9| 3| 3| 2| 2| 5| 3| 9| 1| 3| 2| 7| 2| 3| 3| 5| 3| 6|             
                                           | 5| 9| 1| 9| 7| 3| 0| 5| 0| 0| 9| 1| 7| 0| 3| 7| 0| 9| 9| 9| 1| 1| 7| 1| 1|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    VEHICLE/                               | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    CONTROL                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Galactocele                          |                                                                          |             
                                            __________________________________________________________________________|             
   Skin                                    | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Femur, Osteopetrosis                 |                                                    4                     |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Hemorrhage, Focal                    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Larynx                                  |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Congestion                           |       2                                                                  |             
      Foreign Body                         |                         2                          1                     |             
      Hemorrhage, Focal                    |                                                                          |             
      Hyperplasia, Focal                   |                               2                                          |             
      Inflammation, Acute, Focal           |                                                                          |             
      Inflammation, Chronic, Focal         |                         3                                                |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Foreign Body                         |                                                             1            |             
      Fungus                               |                      X                                                   |             
      Inflammation, Chronic, Focal         |                      3                                                   |             
      Inflammation, Focal, Suppurative     |                                                             2            |             
      Nasolacrimal Duct, Inflammation,     |                                                                          |             
           Chronic                         |                                                                3         |             
      Nasolacrimal Duct, Inflammation,     |                                                                          |             
           Suppurative                     |                                                                          |             
                                            __________________________________________________________________________|             
   Nose, Rectum                            |                                                                          |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |                   +                    +                                 |             
      Cataract                             |                                                                          |             
      Lens, Cataract                       |                                        3                                 |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Cyst                                 |                         X                       X                        |             
      Glomerulosclerosis                   |                                                                          |             
      Hyperplasia                          |                                                                          |             
      Nephropathy, Chronic                 | 4  3  2  3     1  3  3  4  3  3  4     3  4  1  2  2  3  3  3  4     4   |             
      Pigmentation                         |                                              4                           |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   5                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 5| 7| 7| 7| 4| 6| 7| 6| 7| 7| 7| 5| 4| 7| 6| 7| 7| 7| 5| 7| 7| 7| 4| 7| 5|             
                             DAY ON TEST   | 4| 2| 3| 2| 5| 2| 3| 9| 3| 3| 2| 2| 5| 3| 9| 1| 3| 2| 7| 2| 3| 3| 5| 3| 6|             
                                           | 5| 9| 1| 9| 7| 3| 0| 5| 0| 0| 9| 1| 7| 0| 3| 7| 0| 9| 9| 9| 1| 1| 7| 1| 1|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    VEHICLE/                               | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    CONTROL                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
      Pelvis, Hemorrhage                   |                                                                          |             
      Pelvis, Hyperplasia                  |                                                                          |             
      Pelvis, Inflammation, Chronic        |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page   6                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 7| 7| 7| 4| 4| 6| 7| 7| 6| 7| 7| 4| 4| 5| 7| 6| 7| 6| 4| 7| 6|             
                             DAY ON TEST   | 3| 3| 3| 2| 3| 3| 3| 5| 5| 5| 3| 3| 8| 2| 2| 5| 5| 0| 3| 6| 3| 3| 5| 2| 9|             
                                           | 0| 0| 0| 9| 1| 1| 1| 7| 7| 3| 0| 1| 8| 9| 9| 7| 7| 9| 1| 2| 1| 0| 7| 9| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    VEHICLE/                               | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | M  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
      Parasite Metazoan                    |             X                                                           X|             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
      Parasite Metazoan                    |                   X                                                      |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
      Parasite Metazoan                    |                                        X                                 |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
      Angiectasis, Focal                   |                                                                          |             
      Basophilic Focus                     |       X                       X                                         X|             
      Basophilic Focus, Multiple           | X  X     X  X  X  X              X     X  X           X     X        X   |             
      Clear Cell Focus                     | X        X     X              X  X                                   X   |             
      Clear Cell Focus, Multiple           |                                                             X            |             
      Congestion, Focal                    |                                                          2               |             
      Hematocyst                           |                                                                X         |             
      Hepatodiaphragmatic Nodule           |                                                                          |             
      Hepatodiaphragmatic Nodule, Multiple |                                  X                          X            |             
      Hyperplasia, Focal                   |                                                                          |             
      Inflammation, Chronic, Focal         | 4     2  1     3  3           1  2     2              2  1  2        3   |             
      Necrosis, Focal                      |                                                                          |             
      Bile Duct, Hyperplasia               |    2  1  1     1  2        3  2  3  4  2  4           1  2  1  4     1   |             
      Centrilobular, Fatty Change          |                            4        2              3     3     3         |             
      Serosa, Fibrosis, Focal              |       1                                                                  |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                                                          |             
      Fat, Necrosis                        |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
      Atrophy, Focal                       |       2                       1  2        3                    1         |             
      Focal Cellular Change                |                                                                          |             
      Hyperplasia, Focal                   |                                                                2         |             
                                            __________________________________________________________________________|             
   Pharynx                                 |                                                                      +   |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
      Inflammation, Chronic                |                                                                          |             
      Duct, Ectasia, Focal                 |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
      Hyperplasia, Diffuse, Squamous       |                                                          4               |             
      Inflammation, Chronic, Diffuse       |                                                          3               |             
      Ulcer                                |                                                    2                     |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page   7                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 7| 7| 7| 4| 4| 6| 7| 7| 6| 7| 7| 4| 4| 5| 7| 6| 7| 6| 4| 7| 6|             
                             DAY ON TEST   | 3| 3| 3| 2| 3| 3| 3| 5| 5| 5| 3| 3| 8| 2| 2| 5| 5| 0| 3| 6| 3| 3| 5| 2| 9|             
                                           | 0| 0| 0| 9| 1| 1| 1| 7| 7| 3| 0| 1| 8| 9| 9| 7| 7| 9| 1| 2| 1| 0| 7| 9| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    VEHICLE/                               | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
      Erosion                              |                                                                          |             
                                            __________________________________________________________________________|             
   Tooth                                   |                                                                          |             
      Gingiva, Foreign Body                |                                                                          |             
      Gingiva, Hyperplasia, Focal, Squamous|                                                                          |             
      Gingiva, Inflammation, Chronic, Focal|                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
      Inflammation, Chronic, Focal         | 2  2  2  2  2     2           2        2              2     2        2  2|             
      Endocardium, Hemorrhage, Focal       |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
      Angiectasis                          |                                           2                              |             
      Cyst                                 |                                                                          |             
      Cytoplasmic Alteration, Focal        |                                  1                                       |             
      Degeneration, Ballooning, Focal      |                                                                          |             
      Degeneration, Fatty, Focal           | 1        1  1              2  2  1     1           1                     |             
      Hematocyst                           |                                        X                                 |             
      Hyperplasia, Focal                   |                            1        1  2  3           2              2  2|             
      Hypertrophy, Focal                   |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
      Hyperplasia                          |                   1                 1     3           1  1     2        1|             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +  +  +  M  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +  +  +  +     +  +  +  +  +  +  +     +  +  +  +  +  +     +  +|             
      Amyloid Deposition                   | 4                                                                        |             
      Angiectasis                          | 4              3              3                       4                  |             
      Cyst                                 |                            X                       X  X     X  X     X   |             
      Cyst, Multiple                       |                                  X        X                              |             
      Ectasia                              |                                                                          |             
      Pars Distalis, Angiectasis           |                                                                          |             
      Pars Distalis, Hyperplasia, Focal    |                                  2     3                                 |             
      Pars Distalis, Hyperplasia,          |                                                                          |             
          Multifocal                       |    2                                                                     |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
      C-Cell, Hyperplasia, Focal           |          2        2              1                                       |             
      Follicular Cell, Metaplasia, Focal,  |                                                                          |             
           Squamous                        |                                  1                                       |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   8                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 7| 7| 7| 4| 4| 6| 7| 7| 6| 7| 7| 4| 4| 5| 7| 6| 7| 6| 4| 7| 6|             
                             DAY ON TEST   | 3| 3| 3| 2| 3| 3| 3| 5| 5| 5| 3| 3| 8| 2| 2| 5| 5| 0| 3| 6| 3| 3| 5| 2| 9|             
                                           | 0| 0| 0| 9| 1| 1| 1| 7| 7| 3| 0| 1| 8| 9| 9| 7| 7| 9| 1| 2| 1| 0| 7| 9| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    VEHICLE/                               | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Clitoral Gland                          | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  M|             
      Dilatation                           |       2                                                                  |             
      Hyperplasia, Focal                   |                                        3                                 |             
      Inflammation, Chronic, Focal         |                                                                          |             
      Inflammation, Suppurative            |                                                                          |             
                                            __________________________________________________________________________|             
   Ovary                                   | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +  +  +  +|             
      Cyst                                 |                            X  X           X                       X      |             
      Corpus Luteum, Necrosis              |                                                                          |             
      Periovarian Tissue, Necrosis, Focal  |                                                                          |             
                                            __________________________________________________________________________|             
   Uterus                                  | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
      Hyperplasia, Chronic, Cystic         |                3                                                         |             
      Cervix, Fibrosis                     |                                                                          |             
      Serosa, Necrosis                     |                                                                3         |             
                                            __________________________________________________________________________|             
   Vagina                                  |                            +                                             |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
      Myelofibrosis, Focal                 |                                                                          |             
      Erythroid Cell, Proliferation        |                                                                          |             
      Myeloid Cell, Proliferation          |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
      Axillary, Infiltration Cellular,     |                                                                          |             
           Histiocyte                      |                                                                2         |             
      Iliac, Hyperplasia, Plasma Cell      |          3                                                               |             
      Mandibular, Congestion               |                                                                          |             
      Mandibular, Hyperplasia, Plasma Cell |                                                                          |             
      Mediastinal, Hemorrhage              |                                           4                              |             
      Mediastinal, Inflammation,           |                                                                          |             
          Suppurative                      |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
      Congestion                           |          2                                                               |             
      Hemorrhage                           |                                                                         3|             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
      Angiectasis                          |                                                                          |             
      Hematopoietic Cell Proliferation     |                                                                          |             
      Hyperplasia, Lymphoid                | 1                                                                        |             
      Capsule, Fibrosis                    |                                                                          |             
                                            __________________________________________________________________________|             
   Thymus                                  | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
      Cyst                                 |                                                                          |             
      Hemorrhage                           |                                                    2                     |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | +  +  +  +  +  +  +        +  +  +  +  +  +  +     +  +  +  +  +     +  +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page   9                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 7| 7| 7| 4| 4| 6| 7| 7| 6| 7| 7| 4| 4| 5| 7| 6| 7| 6| 4| 7| 6|             
                             DAY ON TEST   | 3| 3| 3| 2| 3| 3| 3| 5| 5| 5| 3| 3| 8| 2| 2| 5| 5| 0| 3| 6| 3| 3| 5| 2| 9|             
                                           | 0| 0| 0| 9| 1| 1| 1| 7| 7| 3| 0| 1| 8| 9| 9| 7| 7| 9| 1| 2| 1| 0| 7| 9| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    VEHICLE/                               | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Galactocele                          |       X                                                                  |             
                                            __________________________________________________________________________|             
   Skin                                    | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
      Femur, Osteopetrosis                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
      Hemorrhage, Focal                    |                                                    4           1         |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Larynx                                  |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
      Congestion                           |                                  2                 2        2            |             
      Foreign Body                         |                                                                          |             
      Hemorrhage, Focal                    |                                                    2                     |             
      Hyperplasia, Focal                   |          1                                                               |             
      Inflammation, Acute, Focal           |                                                                          |             
      Inflammation, Chronic, Focal         |          2                             1           2                    1|             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
      Foreign Body                         |                                                                          |             
      Fungus                               |                                                                          |             
      Inflammation, Chronic, Focal         |                2                                                         |             
      Inflammation, Focal, Suppurative     |                                                                          |             
      Nasolacrimal Duct, Inflammation,     |                                                                          |             
           Chronic                         |                                                                          |             
      Nasolacrimal Duct, Inflammation,     |                                                                          |             
           Suppurative                     |                                                                      2   |             
                                            __________________________________________________________________________|             
   Nose, Rectum                            |                                                                          |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |                      +                                                   |             
      Cataract                             |                      3                                                   |             
      Lens, Cataract                       |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
      Cyst                                 |                                                                          |             
      Glomerulosclerosis                   |                                           3                              |             
      Hyperplasia                          |                                                                          |             
      Nephropathy, Chronic                 | 2  2  4  3  4  2  2        1  3  2  2  2           1  3  4  3  2     2  2|             
      Pigmentation                         |                                           3                    2         |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  10                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 7| 7| 7| 4| 4| 6| 7| 7| 6| 7| 7| 4| 4| 5| 7| 6| 7| 6| 4| 7| 6|             
                             DAY ON TEST   | 3| 3| 3| 2| 3| 3| 3| 5| 5| 5| 3| 3| 8| 2| 2| 5| 5| 0| 3| 6| 3| 3| 5| 2| 9|             
                                           | 0| 0| 0| 9| 1| 1| 1| 7| 7| 3| 0| 1| 8| 9| 9| 7| 7| 9| 1| 2| 1| 0| 7| 9| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    VEHICLE/                               | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
      Pelvis, Hemorrhage                   |                                                                          |             
      Pelvis, Hyperplasia                  |                                                                      3   |             
      Pelvis, Inflammation, Chronic        |                                                                      2   |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +  +  +  +        +  +  +  +  +  +        +  +  +  +  +     +  +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page  11                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 6| 7| 7| 7| 7| 4| 7| 4|                                            |            |
                             DAY ON TEST   | 3| 1| 2| 3| 2| 2| 3| 5| 2| 5|                                            |            |
                                           | 1| 7| 9| 0| 9| 9| 0| 7| 9| 7|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|                                            |      A     |
    VEHICLE/                               | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |      L     |
    CONTROL                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               | +  +  +  +  +  +  +     +                                                |  48        |
                                            __________________________________________________________________________|____________|
   Intestine Large                         | +  +  +  +  +     +     +                                                |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +  +  +  +  +  +  +     +                                                |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  | +  +  +  +  +  +  +     +                                                |  50        |
      Parasite Metazoan                    | X                                                                        |      6     |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +  +  +  +  +  +  +     +                                                |  50        |
      Parasite Metazoan                    |                X                                                         |      5     |
                                            __________________________________________________________________________|____________|
   Intestine Small                         | +  +  +  +  +  +  +     +                                                |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  +  +  +  +  +  +     +                                                |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  +  +  +  +  +  +     +                                                |  50        |
      Parasite Metazoan                    |                                                                          |      1     |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +  +  +  +  +  +  +     +                                                |  50        |
                                            __________________________________________________________________________|____________|
   Liver                                   | +  +  +  +  +  +  +  +  +                                                |  51        |
      Angiectasis, Focal                   |                         2                                                |      3  2.3|
      Basophilic Focus                     |             X  X        X                                                |      9     |
      Basophilic Focus, Multiple           | X  X  X  X        X                                                      |     32     |
      Clear Cell Focus                     |                                                                          |     10     |
      Clear Cell Focus, Multiple           |                                                                          |      2     |
      Congestion, Focal                    |                                                                          |      1  2.0|
      Hematocyst                           |                                                                          |      1     |
      Hepatodiaphragmatic Nodule           |    X                    X                                                |      4     |
      Hepatodiaphragmatic Nodule, Multiple |                                                                          |      4     |
      Hyperplasia, Focal                   |                      3                                                   |      1  3.0|
      Inflammation, Chronic, Focal         | 1        4  2  4                                                         |     32  2.1|
      Necrosis, Focal                      |       3                                                                  |      1  3.0|
      Bile Duct, Hyperplasia               | 1  2           4  1                                                      |     32  2.0|
      Centrilobular, Fatty Change          |                                                                          |      7  3.0|
      Serosa, Fibrosis, Focal              |                                                                          |      2  1.0|
                                            __________________________________________________________________________|____________|
   Mesentery                               |    +                                                                     |   2        |
      Fat, Necrosis                        |    3                                                                     |      2  3.5|
                                            __________________________________________________________________________|____________|
   Pancreas                                | +  +  +  +  +  +  +     +                                                |  50        |
      Atrophy, Focal                       | 2     2  1        2     2                                                |     17  1.7|
      Focal Cellular Change                |                                                                          |      1     |
      Hyperplasia, Focal                   |                                                                          |      2  2.0|
                                            __________________________________________________________________________|____________|
   Pharynx                                 |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Salivary Glands                         | +  +  +  +  +  +  +     +                                                |  50        |
      Inflammation, Chronic                |                                                                          |      1  2.0|
      Duct, Ectasia, Focal                 |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Stomach                                 | +  +  +  +  +  +  +     +                                                |  50        |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  12                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 6| 7| 7| 7| 7| 4| 7| 4|                                            |            |
                             DAY ON TEST   | 3| 1| 2| 3| 2| 2| 3| 5| 2| 5|                                            |            |
                                           | 1| 7| 9| 0| 9| 9| 0| 7| 9| 7|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|                                            |      A     |
    VEHICLE/                               | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |      L     |
    CONTROL                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM - cont                  |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    | +  +  +  +  +  +  +     +                                                |  50        |
      Hyperplasia, Diffuse, Squamous       |                                                                          |      1  4.0|
      Inflammation, Chronic, Diffuse       |                                                                          |      1  3.0|
      Ulcer                                |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +  +  +  +  +  +     +                                                |  50        |
      Erosion                              |                                                                          |      1  1.0|
                                            __________________________________________________________________________|____________|
   Tooth                                   |                                                                          |   1        |
      Gingiva, Foreign Body                |                                                                          |      1  3.0|
      Gingiva, Hyperplasia, Focal, Squamous|                                                                          |      1  3.0|
      Gingiva, Inflammation, Chronic, Focal|                                                                          |      1  3.0|
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Heart                                   | +  +  +  +  +  +  +     +                                                |  50        |
      Inflammation, Chronic, Focal         | 2  2     2  2  2  2     2                                                |     28  2.0|
      Endocardium, Hemorrhage, Focal       |                                                                          |      1  2.0|
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           | +  +  +  +  +  +  +     +                                                |  50        |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   | +  +  +  +  +  +  +     +                                                |  50        |
      Angiectasis                          |                                                                          |      4  2.0|
      Cyst                                 |                                                                          |      1     |
      Cytoplasmic Alteration, Focal        |                                                                          |      2  1.0|
      Degeneration, Ballooning, Focal      |                                                                          |      1  4.0|
      Degeneration, Fatty, Focal           |    2  1           2                                                      |     17  1.6|
      Hematocyst                           |                X                                                         |      2     |
      Hyperplasia, Focal                   |             1     2                                                      |     14  1.9|
      Hypertrophy, Focal                   |                                                                          |      2  2.0|
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  | +  +  +  +  +  +  +     +                                                |  48        |
      Hyperplasia                          | 2  1        1           2                                                |     14  1.4|
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      | +  +  +  +  +  +  +     +                                                |  50        |
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       | +  +  +  +  +  +  +     +                                                |  46        |
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         | +  +  +  I  +  +  +     +                                                |  53        |
      Amyloid Deposition                   |                                                                          |      1  4.0|
      Angiectasis                          |    2        4     3                                                      |     10  3.3|
      Cyst                                 | X  X        X  X  X                                                      |     17     |
      Cyst, Multiple                       |                                                                          |      4     |
      Ectasia                              |                                                                          |      1  3.0|
      Pars Distalis, Angiectasis           |                                                                          |      1  2.0|
      Pars Distalis, Hyperplasia, Focal    |    2                                                                     |      8  2.4|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  13                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 6| 7| 7| 7| 7| 4| 7| 4|                                            |            |
                             DAY ON TEST   | 3| 1| 2| 3| 2| 2| 3| 5| 2| 5|                                            |            |
                                           | 1| 7| 9| 0| 9| 9| 0| 7| 9| 7|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|                                            |      A     |
    VEHICLE/                               | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |      L     |
    CONTROL                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
      Pars Distalis, Hyperplasia,          |                                                                          |            |
          Multifocal                       |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           | +  +  +  +  +  +  +     +                                                |  50        |
      C-Cell, Hyperplasia, Focal           |          2     1                                                         |      9  1.8|
      Follicular Cell, Metaplasia, Focal,  |                                                                          |            |
           Squamous                        |                                                                          |      1  1.0|
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Clitoral Gland                          | +  +  +  +  M  +  +     +                                                |  46        |
      Dilatation                           |                                                                          |      2  3.0|
      Hyperplasia, Focal                   |                                                                          |      3  3.0|
      Inflammation, Chronic, Focal         |          2                                                               |      5  2.0|
      Inflammation, Suppurative            |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Ovary                                   | +  +  +  +  +  +  +     +                                                |  52        |
      Cyst                                 |                                                                          |      7     |
      Corpus Luteum, Necrosis              |                                                                          |      1  4.0|
      Periovarian Tissue, Necrosis, Focal  |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Uterus                                  | +  +  +  +  +  +  +     +                                                |  51        |
      Hyperplasia, Chronic, Cystic         |    2           3                                                         |      4  2.5|
      Cervix, Fibrosis                     |          4                                                               |      1  4.0|
      Serosa, Necrosis                     |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Vagina                                  |                         +                                                |   2        |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             | +  +  +  +  +  +  +     +                                                |  50        |
      Myelofibrosis, Focal                 |                                                                          |      1  3.0|
      Erythroid Cell, Proliferation        |                                                                          |      1  3.0|
      Myeloid Cell, Proliferation          |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Lymph Node                              | +  +  +  +  +  +  +     +                                                |  50        |
      Axillary, Infiltration Cellular,     |                                                                          |            |
           Histiocyte                      |                                                                          |      1  2.0|
      Iliac, Hyperplasia, Plasma Cell      |                                                                          |      1  3.0|
      Mandibular, Congestion               |                                                                          |      1  4.0|
      Mandibular, Hyperplasia, Plasma Cell |       4                                                                  |      2  4.0|
      Mediastinal, Hemorrhage              |                                                                          |      1  4.0|
      Mediastinal, Inflammation,           |                                                                          |            |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  14                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 6| 7| 7| 7| 7| 4| 7| 4|                                            |            |
                             DAY ON TEST   | 3| 1| 2| 3| 2| 2| 3| 5| 2| 5|                                            |            |
                                           | 1| 7| 9| 0| 9| 9| 0| 7| 9| 7|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|                                            |      A     |
    VEHICLE/                               | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |      L     |
    CONTROL                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
          Suppurative                      |       2                                                                  |      1  2.0|
                                            __________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  | +  +  +  +  +  +  +     +                                                |  50        |
      Congestion                           |                                                                          |      1  2.0|
      Hemorrhage                           |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Spleen                                  | +  +  +  +  +  +  +     +                                                |  50        |
      Angiectasis                          |       2                                                                  |      1  2.0|
      Hematopoietic Cell Proliferation     |    4                                                                     |      4  3.0|
      Hyperplasia, Lymphoid                |                                                                          |      1  1.0|
      Capsule, Fibrosis                    |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Thymus                                  | +  +  M  +  +  +  +     +                                                |  47        |
      Cyst                                 |                                                                          |      1     |
      Hemorrhage                           |                                                                          |      1  2.0|
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           | +  +  +  +  +  +  +     +                                                |  51        |
      Galactocele                          |                                                                          |      1     |
                                            __________________________________________________________________________|____________|
   Skin                                    | +  +  +  +  +  +  +     +                                                |  50        |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    | +  +  +  +  +  +  +     +                                                |  50        |
      Femur, Osteopetrosis                 |                                                                          |      1  4.0|
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   | +  +  +  +  +  +  +     +                                                |  50        |
      Hemorrhage, Focal                    |                                                                          |      2  2.5|
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Larynx                                  |    +                                                                     |   1        |
                                            __________________________________________________________________________|____________|
   Lung                                    | +  +  +  +  +  +  +     +                                                |  50        |
      Congestion                           |          2     2  2                                                      |      7  2.0|
      Foreign Body                         |       2                                                                  |      3  1.7|
      Hemorrhage, Focal                    |                                                                          |      1  2.0|
      Hyperplasia, Focal                   |                                                                          |      2  1.5|
      Inflammation, Acute, Focal           |       3                                                                  |      1  3.0|
      Inflammation, Chronic, Focal         |    1                                                                     |      6  1.7|
                                            __________________________________________________________________________|____________|
   Nose                                    | +  +  +  +  +     +     +                                                |  49        |
      Foreign Body                         |                                                                          |      1  1.0|
      Fungus                               |                                                                          |      1     |
      Inflammation, Chronic, Focal         |                                                                          |      2  2.5|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  15                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 6| 7| 7| 7| 7| 4| 7| 4|                                            |            |
                             DAY ON TEST   | 3| 1| 2| 3| 2| 2| 3| 5| 2| 5|                                            |            |
                                           | 1| 7| 9| 0| 9| 9| 0| 7| 9| 7|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|                                            |      A     |
    VEHICLE/                               | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |      L     |
    CONTROL                                | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 RESPIRATORY SYSTEM - cont                 |                                                                          |            |
                                           |                                                                          |            |
      Inflammation, Focal, Suppurative     |                                                                          |      1  2.0|
      Nasolacrimal Duct, Inflammation,     |                                                                          |            |
           Chronic                         |                                                                          |      1  3.0|
      Nasolacrimal Duct, Inflammation,     |                                                                          |            |
           Suppurative                     |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Nose, Rectum                            |                +                                                         |   1        |
                                            __________________________________________________________________________|____________|
   Trachea                                 | +  +  +  +  +  +  +     +                                                |  50        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Eye                                     |                                                                          |   3        |
      Cataract                             |                                                                          |      1  3.0|
      Lens, Cataract                       |                                                                          |      1  3.0|
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  | +  +  +  +  +  +  +     +                                                |  50        |
      Cyst                                 |                                                                          |      2     |
      Glomerulosclerosis                   |                                                                          |      1  3.0|
      Hyperplasia                          | 4                                                                        |      1  4.0|
      Nephropathy, Chronic                 | 4  2     2  2  2  3     4                                                |     47  2.7|
      Pigmentation                         |    2                                                                     |      4  2.8|
      Pelvis, Hemorrhage                   | 3                                                                        |      1  3.0|
      Pelvis, Hyperplasia                  |                                                                          |      1  3.0|
      Pelvis, Inflammation, Chronic        | 4                                                                        |      2  3.0|
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         | +  +  +  +  +  +  +     +                                                |  50        |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  16                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 4| 6| 6| 7| 7| 7| 4| 4| 7| 7| 6| 7| 7| 4| 7| 7| 4| 7| 6| 7| 4|             
                             DAY ON TEST   | 3| 3| 3| 3| 5| 7| 7| 3| 2| 2| 5| 5| 2| 3| 6| 3| 3| 5| 2| 3| 5| 2| 7| 3| 5|             
                                           | 1| 1| 1| 1| 7| 3| 4| 1| 9| 9| 7| 7| 9| 1| 3| 1| 1| 7| 9| 0| 7| 9| 4| 1| 7|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
    50 MG/KG                               | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +  +  +     +  +  +  M  +        +  +  M  +  +     +  +     +  +  +   |             
      Abscess                              |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Parasite Metazoan                    |                         X                                                |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Parasite Metazoan                    |                      X                                X                  |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Parasite Metazoan                    |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Inflammation, Chronic                |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Angiectasis, Focal                   |                   1                                                      |             
      Basophilic Focus                     |       X              X                 X     X  X        X               |             
      Basophilic Focus, Multiple           | X  X     X        X     X  X        X                 X        X     X   |             
      Clear Cell Focus                     |       X                                               X                  |             
      Clear Cell Focus, Multiple           |                            X                    X                        |             
      Congestion, Focal                    |    2  2                                                                  |             
      Cytoplasmic Alteration, Focal        | 2                                                                    2   |             
      Granuloma, Focal                     |                                                                          |             
      Hepatodiaphragmatic Nodule           |                            X                          X              X   |             
      Hepatodiaphragmatic Nodule, Multiple |                                                                          |             
      Inflammation, Chronic, Focal         | 1        2           1     1        2  1  2  2  1        2     2     2   |             
      Necrosis, Focal                      |                                                                          |             
      Bile Duct, Cyst                      |                                                       X                  |             
      Bile Duct, Hyperplasia               |    2     1     3  1  1  1                       1     1        1  3  1   |             
      Centrilobular, Atrophy, Diffuse      |                                                                          |             
      Centrilobular, Fatty Change          |                4                                                  4      |             
      Serosa, Fibrosis, Focal              |                                                                2         |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Atrophy, Focal                       | 3  2                 2  2           2                 1  1           1   |             
      Focal Cellular Change                |                                                                          |             
      Hyperplasia, Focal                   |                                                                          |             
      Metaplasia, Focal                    |    2                                                                     |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Atrophy                              |                                                                          |             
      Inflammation, Chronic                |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Hyperplasia, Focal, Squamous         |                                                                          |             
      Inflammation, Chronic, Focal         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  17                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 4| 6| 6| 7| 7| 7| 4| 4| 7| 7| 6| 7| 7| 4| 7| 7| 4| 7| 6| 7| 4|             
                             DAY ON TEST   | 3| 3| 3| 3| 5| 7| 7| 3| 2| 2| 5| 5| 2| 3| 6| 3| 3| 5| 2| 3| 5| 2| 7| 3| 5|             
                                           | 1| 1| 1| 1| 7| 3| 4| 1| 9| 9| 7| 7| 9| 1| 3| 1| 1| 7| 9| 0| 7| 9| 4| 1| 7|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
    50 MG/KG                               | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
      Ulcer                                |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Erosion                              |                                                                          |             
      Ulcer                                |                                                                   3      |             
                                            __________________________________________________________________________|             
   Tongue                                  |                                                                          |             
      Epithelium, Hyperplasia, Focal       |                                                                          |             
                                            __________________________________________________________________________|             
   Tooth                                   |    +                                                                     |             
      Inflammation, Chronic                |    3                                                                     |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Inflammation, Chronic, Focal         |    2     2     2  1        2        2  2     2        2                  |             
      Thrombosis                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Angiectasis                          |                                                                      3   |             
      Cytoplasmic Alteration, Focal        |                                                                          |             
      Degeneration, Fatty, Focal           |                   2     2                       1        2        2      |             
      Hemorrhage, Focal                    |                                                                          |             
      Hyperplasia, Focal                   | 2                                   2        3                           |             
      Mineralization, Focal                |                      3                                                   |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Hyperplasia                          |          1                             2     1           1        2      |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Hyperplasia, Focal                   |                                                                          |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +  +  +  +     +  M  +  +  M        +  +  +  +  +     +  M     +  M  +   |             
      Hyperplasia, Focal                   |                                                                          |             
      Hypoplasia, Diffuse                  |                                                                          |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Angiectasis                          | 2                          3                                             |             
      Cyst                                 | X  X     X              X  X        X                 X  X           X   |             
      Cyst, Multiple                       |                      X                                            X      |             
      Pigmentation, Focal                  |                                                                          |             
      Pars Distalis, Angiectasis, Focal    |                                                                   2      |             
      Pars Distalis, Hyperplasia, Focal    |          2        2                                                      |             
      Pars Distalis, Metaplasia, Focal,    |                                                                          |             
           Osseous                         |                                           3                              |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Hemorrhage, Multifocal               |                                                                          |             
      C-Cell, Hyperplasia, Focal           |                                              2  1     2        1         |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  18                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 4| 6| 6| 7| 7| 7| 4| 4| 7| 7| 6| 7| 7| 4| 7| 7| 4| 7| 6| 7| 4|             
                             DAY ON TEST   | 3| 3| 3| 3| 5| 7| 7| 3| 2| 2| 5| 5| 2| 3| 6| 3| 3| 5| 2| 3| 5| 2| 7| 3| 5|             
                                           | 1| 1| 1| 1| 7| 3| 4| 1| 9| 9| 7| 7| 9| 1| 3| 1| 1| 7| 9| 0| 7| 9| 4| 1| 7|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
    50 MG/KG                               | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Clitoral Gland                          | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Atrophy                              |                4                                                         |             
      Hyperplasia, Focal                   |                                              2                           |             
      Inflammation, Chronic, Focal         | 2                                                                        |             
                                            __________________________________________________________________________|             
   Ovary                                   | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Congestion                           |                                                                          |             
      Cyst                                 |                            X                                             |             
      Granuloma, Focal                     |                                                                          |             
                                            __________________________________________________________________________|             
   Uterus                                  | +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +   |             
      Dilatation                           |                                                                          |             
      Fibrosis                             |                                                                   4  4   |             
      Hydrometra                           |                                                                          |             
      Cervix, Fibrosis                     |                                                          4               |             
      Lumen, Hemorrhage                    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Myelofibrosis, Focal                 |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Iliac, Ectasia                       |                                                                          |             
      Iliac, Infiltration Cellular,        |                                                                          |             
          Histiocyte                       |                                                                          |             
      Mandibular, Congestion               |                                                                          |             
      Mandibular, Hyperplasia, Plasma Cell |                                                       2                  |             
      Mediastinal, Congestion              |                                                                          |             
      Mediastinal, Hyperplasia, Lymphoid   |                                                                          |             
      Mediastinal, Hyperplasia, Plasma Cell|                                                                   3      |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Congestion                           |                                                                          |             
      Fibrosis, Focal                      |                   2                                                      |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Hematopoietic Cell Proliferation     |                                                                          |             
                                            __________________________________________________________________________|             
   Thymus                                  | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  M  +   |             
      Cyst                                 |                                                                          |             
      Cyst, Multiple                       |                                                                      X   |             
      Hemorrhage                           |                                                                          |             
      Mediastinum, Inflammation, Acute     |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Galactocele                          |                                                                          |             
      Galactocele, Multiple                |                                                                          |             
                                            __________________________________________________________________________|             
   Skin                                    | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  19                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 4| 6| 6| 7| 7| 7| 4| 4| 7| 7| 6| 7| 7| 4| 7| 7| 4| 7| 6| 7| 4|             
                             DAY ON TEST   | 3| 3| 3| 3| 5| 7| 7| 3| 2| 2| 5| 5| 2| 3| 6| 3| 3| 5| 2| 3| 5| 2| 7| 3| 5|             
                                           | 1| 1| 1| 1| 7| 3| 4| 1| 9| 9| 7| 7| 9| 1| 3| 1| 1| 7| 9| 0| 7| 9| 4| 1| 7|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
    50 MG/KG                               | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM - cont             |                                                                          |             
                                           |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Cranium, Hyperostosis                |                                                                          |             
      Femur, Hyperostosis                  |                                     X     X                              |             
      Femur, Osteopetrosis                 |                                                                          |             
      Turbinate, Hyperostosis              |                                           X                              |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Hemorrhage, Focal                    |                1                                                         |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Congestion                           |                            2              3              2           2   |             
      Emphysema, Focal                     |                                                                          |             
      Hemorrhage, Focal                    |                      2                                                   |             
      Hyperplasia, Focal                   |                                                                2         |             
      Inflammation, Chronic, Focal         |                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Foreign Body                         |                                                                          |             
      Fungus                               |                                                          X               |             
      Inflammation, Chronic, Focal         |                                                                          |             
      Inflammation, Focal, Suppurative     |                                                          2               |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |    +                                                     +               |             
      Atrophy                              |                                                          4               |             
      Synechia                             |                                                          3               |             
      Lens, Cataract                       |    2                                                     3               |             
      Retina, Degeneration                 |                                                          4               |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
      Congestion                           |                                                                          |             
      Cyst                                 |                X                                                         |             
      Hemorrhage, Focal                    |                                                                          |             
      Nephropathy, Chronic                 | 3  3  2  2     2  2  3  2  2        1  4  2  2  3     2  1        2  4   |             
      Pigmentation                         |                   2                                               4      |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +     +  +  +  +  +        +  +  +  +  +     +  +     +  +  +   |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  20                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 4| 7| 5| 1| 7| 7| 7| 6| 7| 7| 6| 7| 7| 4| 6| 7| 4| 7| 6| 7| 6| 7| 7|             
                             DAY ON TEST   | 3| 3| 7| 2| 2| 0| 3| 3| 1| 7| 3| 2| 4| 3| 2| 5| 2| 2| 5| 2| 9| 3| 6| 3| 3|             
                                           | 0| 1| 2| 9| 4| 1| 1| 0| 6| 8| 0| 9| 6| 0| 9| 7| 9| 9| 7| 9| 3| 0| 8| 0| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    50 MG/KG                               | 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  M  +  +  +|             
      Abscess                              |                3                                                         |             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Parasite Metazoan                    |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Parasite Metazoan                    |    X                                                                     |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Parasite Metazoan                    |    X              X                    X           X                     |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Inflammation, Chronic                |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Angiectasis, Focal                   |                                     2                                    |             
      Basophilic Focus                     |          X        X        X  X           X                    X         |             
      Basophilic Focus, Multiple           | X  X        X        X  X        X  X  X           X     X  X     X     X|             
      Clear Cell Focus                     |                         X                                X               |             
      Clear Cell Focus, Multiple           | X        X                                                               |             
      Congestion, Focal                    |                                                                2         |             
      Cytoplasmic Alteration, Focal        |                                                                      2   |             
      Granuloma, Focal                     |                                                                         3|             
      Hepatodiaphragmatic Nodule           |    X                 X  X                                      X     X  X|             
      Hepatodiaphragmatic Nodule, Multiple |                                  X     X                                 |             
      Inflammation, Chronic, Focal         | 1        1        3  3                 2           3     2  1  1  2     4|             
      Necrosis, Focal                      |                      3              2                                    |             
      Bile Duct, Cyst                      |                                                                          |             
      Bile Duct, Hyperplasia               |    1     1  1        2           2     3  2     2              1  2      |             
      Centrilobular, Atrophy, Diffuse      |                                     3                                    |             
      Centrilobular, Fatty Change          |       4        2                                                     4   |             
      Serosa, Fibrosis, Focal              |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  M     +  +     +  +  +  +  +  +|             
      Atrophy, Focal                       |    1        1           1           2              2                     |             
      Focal Cellular Change                | X                                                                        |             
      Hyperplasia, Focal                   |                      2                                                   |             
      Metaplasia, Focal                    |                                                                          |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Atrophy                              |                                                 3                        |             
      Inflammation, Chronic                |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Hyperplasia, Focal, Squamous         |                                           3                              |             
      Inflammation, Chronic, Focal         |       2                                   3     3                        |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  21                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 4| 7| 5| 1| 7| 7| 7| 6| 7| 7| 6| 7| 7| 4| 6| 7| 4| 7| 6| 7| 6| 7| 7|             
                             DAY ON TEST   | 3| 3| 7| 2| 2| 0| 3| 3| 1| 7| 3| 2| 4| 3| 2| 5| 2| 2| 5| 2| 9| 3| 6| 3| 3|             
                                           | 0| 1| 2| 9| 4| 1| 1| 0| 6| 8| 0| 9| 6| 0| 9| 7| 9| 9| 7| 9| 3| 0| 8| 0| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    50 MG/KG                               | 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
      Ulcer                                |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Erosion                              |       3                                                                  |             
      Ulcer                                |                                                 3                        |             
                                            __________________________________________________________________________|             
   Tongue                                  | +                                                                        |             
      Epithelium, Hyperplasia, Focal       | 2                                                                        |             
                                            __________________________________________________________________________|             
   Tooth                                   | +                                               +                        |             
      Inflammation, Chronic                | 3                                                                        |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Inflammation, Chronic, Focal         | 2  2     2        3  2  2  2        2  2           2     2     2     2  2|             
      Thrombosis                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Angiectasis                          |                   2  2                                                   |             
      Cytoplasmic Alteration, Focal        |                               2                                          |             
      Degeneration, Fatty, Focal           |                         2     2  3     2                 2     2     2   |             
      Hemorrhage, Focal                    |             3                                                            |             
      Hyperplasia, Focal                   |          3  3        3  2              3           2                    3|             
      Mineralization, Focal                |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +  +  +  +  +  +  +  M  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Hyperplasia                          |    1     2              2                          1     1           2   |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  +  +  M  +  +  +  +     +  +     +  I  +  +  I  +|             
      Hyperplasia, Focal                   | 3                    2                                                   |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +  +  +  +  M  +  M  +  M  +  +  +  M  +  +     +  +     M  +  +  M  +  +|             
      Hyperplasia, Focal                   |                      3                                                   |             
      Hypoplasia, Diffuse                  |                                                 3                        |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Angiectasis                          |          3  4           3                                4               |             
      Cyst                                 | X  X     X        X     X     X  X  X  X        X        X           X  X|             
      Cyst, Multiple                       |                                                    X                     |             
      Pigmentation, Focal                  |          3                                                               |             
      Pars Distalis, Angiectasis, Focal    |                                     3                          4         |             
      Pars Distalis, Hyperplasia, Focal    |       3  3        2                    2                 2              2|             
      Pars Distalis, Metaplasia, Focal,    |                                                                          |             
           Osseous                         |                                                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Hemorrhage, Multifocal               |                            2                                             |             
      C-Cell, Hyperplasia, Focal           | 3  2  1                                1                 1           2   |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  22                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 4| 7| 5| 1| 7| 7| 7| 6| 7| 7| 6| 7| 7| 4| 6| 7| 4| 7| 6| 7| 6| 7| 7|             
                             DAY ON TEST   | 3| 3| 7| 2| 2| 0| 3| 3| 1| 7| 3| 2| 4| 3| 2| 5| 2| 2| 5| 2| 9| 3| 6| 3| 3|             
                                           | 0| 1| 2| 9| 4| 1| 1| 0| 6| 8| 0| 9| 6| 0| 9| 7| 9| 9| 7| 9| 3| 0| 8| 0| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    50 MG/KG                               | 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Clitoral Gland                          | +  +  M  +  +  +  +  +  M  +  +  +  +  +  +     M  +     +  +  +  M  +  +|             
      Atrophy                              |                                                                          |             
      Hyperplasia, Focal                   |             3                                                  3         |             
      Inflammation, Chronic, Focal         |                                                          3  2           2|             
                                            __________________________________________________________________________|             
   Ovary                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Congestion                           |                         2           2                                    |             
      Cyst                                 |                                        X                             X   |             
      Granuloma, Focal                     |                                                                         3|             
                                            __________________________________________________________________________|             
   Uterus                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Dilatation                           |          3              2                                                |             
      Fibrosis                             |                                                                          |             
      Hydrometra                           | 4                                                                        |             
      Cervix, Fibrosis                     |                                                                          |             
      Lumen, Hemorrhage                    |                   4                                                      |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Myelofibrosis, Focal                 |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Iliac, Ectasia                       |                                                                          |             
      Iliac, Infiltration Cellular,        |                                                                          |             
          Histiocyte                       |                                                                          |             
      Mandibular, Congestion               |                                     3                                    |             
      Mandibular, Hyperplasia, Plasma Cell |                                                                          |             
      Mediastinal, Congestion              |                         3           2                                    |             
      Mediastinal, Hyperplasia, Lymphoid   |                                                                          |             
      Mediastinal, Hyperplasia, Plasma Cell|                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Congestion                           |                                     3                                    |             
      Fibrosis, Focal                      |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Hematopoietic Cell Proliferation     |                         3           3                                    |             
                                            __________________________________________________________________________|             
   Thymus                                  | +  +  +  +  +  +  +  +  +  M  +  +  +  +  +     +  +     +  M  +  +  M  +|             
      Cyst                                 |                                           X                              |             
      Cyst, Multiple                       |                                                                          |             
      Hemorrhage                           |                3                                                         |             
      Mediastinum, Inflammation, Acute     |                3                                                         |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Galactocele                          |                                                                          |             
      Galactocele, Multiple                |                                                                          |             
                                            __________________________________________________________________________|             
   Skin                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  23                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 4| 7| 5| 1| 7| 7| 7| 6| 7| 7| 6| 7| 7| 4| 6| 7| 4| 7| 6| 7| 6| 7| 7|             
                             DAY ON TEST   | 3| 3| 7| 2| 2| 0| 3| 3| 1| 7| 3| 2| 4| 3| 2| 5| 2| 2| 5| 2| 9| 3| 6| 3| 3|             
                                           | 0| 1| 2| 9| 4| 1| 1| 0| 6| 8| 0| 9| 6| 0| 9| 7| 9| 9| 7| 9| 3| 0| 8| 0| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    50 MG/KG                               | 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM - cont             |                                                                          |             
                                           |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Cranium, Hyperostosis                |          X                                                               |             
      Femur, Hyperostosis                  |                         X                                                |             
      Femur, Osteopetrosis                 |          4                                4                              |             
      Turbinate, Hyperostosis              |                         X                                                |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Hemorrhage, Focal                    |             4                                                            |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Congestion                           |             4  3     2     3              2              2              2|             
      Emphysema, Focal                     |                         2                                                |             
      Hemorrhage, Focal                    |                                                                          |             
      Hyperplasia, Focal                   | 2                                   2                       2            |             
      Inflammation, Chronic, Focal         |                   1     1                                                |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Foreign Body                         |                                                    1                     |             
      Fungus                               |                                                    X                     |             
      Inflammation, Chronic, Focal         |                                                    3                     |             
      Inflammation, Focal, Suppurative     |                                  1                                       |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |          +                                +                       +     +|             
      Atrophy                              |                                                                   4      |             
      Synechia                             |                                           3                              |             
      Lens, Cataract                       |          2                                2                       4      |             
      Retina, Degeneration                 |          4                                4                       4      |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                                                                         +|             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
      Congestion                           |                         3                                   2            |             
      Cyst                                 |                                                                          |             
      Hemorrhage, Focal                    |                   2                                                      |             
      Nephropathy, Chronic                 | 2  2     3  2     3  2  2  3  3  2  3  4  3     1  1     2  1  3  3  2  2|             
      Pigmentation                         |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page  24                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 __________________________________________________________________________________________________________________________________ 
                                           | 6| 4| 7| 4| 7| 7| 7| 6| 6| 6|                                            |            |
                             DAY ON TEST   | 5| 5| 3| 5| 2| 3| 3| 9| 8| 8|                                            |            |
                                           | 6| 7| 0| 7| 9| 0| 0| 9| 0| 1|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|                                            |      A     |
    50 MG/KG                               | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|                                            |      L     |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               | +     +     +  +  +  +  +  +                                             |  47        |
      Abscess                              |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Intestine Large                         | +     +     +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +     +     +  +  +  +  +  +                                             |  50        |
      Parasite Metazoan                    |                                                                          |      1     |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  | +     +     +  +  +  +  +  +                                             |  50        |
      Parasite Metazoan                    |                   X                                                      |      4     |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +     +     +  +  +  +  +  +                                             |  50        |
      Parasite Metazoan                    |                                                                          |      4     |
                                            __________________________________________________________________________|____________|
   Intestine Small                         | +     +     +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +     +     +  +  +  +  +  +                                             |  50        |
      Inflammation, Chronic                |                      3                                                   |      1  3.0|
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +     +     +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +     +     +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Liver                                   | +     +     +  +  +  +  +  +                                             |  50        |
      Angiectasis, Focal                   |                      2                                                   |      3  1.7|
      Basophilic Focus                     |                      X     X                                             |     14     |
      Basophilic Focus, Multiple           |       X     X  X  X                                                      |     27     |
      Clear Cell Focus                     |             X                                                            |      5     |
      Clear Cell Focus, Multiple           |                                                                          |      4     |
      Congestion, Focal                    |                                                                          |      3  2.0|
      Cytoplasmic Alteration, Focal        |                                                                          |      3  2.0|
      Granuloma, Focal                     |                                                                          |      1  3.0|
      Hepatodiaphragmatic Nodule           |                                                                          |      9     |
      Hepatodiaphragmatic Nodule, Multiple |                                                                          |      2     |
      Inflammation, Chronic, Focal         |       2     2                                                            |     25  1.8|
      Necrosis, Focal                      |                                                                          |      2  2.5|
      Bile Duct, Cyst                      |                                                                          |      1     |
      Bile Duct, Hyperplasia               |                   1        3                                             |     23  1.6|
      Centrilobular, Atrophy, Diffuse      |                                                                          |      1  3.0|
      Centrilobular, Fatty Change          | 4                    3     2                                             |      8  3.4|
      Serosa, Fibrosis, Focal              |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Pancreas                                | +     +     +  +  +  +  +  +                                             |  49        |
      Atrophy, Focal                       |       2           2                                                      |     15  1.7|
      Focal Cellular Change                |                                                                          |      1     |
      Hyperplasia, Focal                   |                                                                          |      1  2.0|
      Metaplasia, Focal                    |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Salivary Glands                         | +     +     +  +  +  +  +  +                                             |  50        |
      Atrophy                              |                      3  2                                                |      3  2.7|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  25                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 __________________________________________________________________________________________________________________________________ 
                                           | 6| 4| 7| 4| 7| 7| 7| 6| 6| 6|                                            |            |
                             DAY ON TEST   | 5| 5| 3| 5| 2| 3| 3| 9| 8| 8|                                            |            |
                                           | 6| 7| 0| 7| 9| 0| 0| 9| 0| 1|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|                                            |      A     |
    50 MG/KG                               | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|                                            |      L     |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM - cont                  |                                                                          |            |
                                           |                                                                          |            |
      Inflammation, Chronic                |                      2                                                   |      1  2.0|
                                            __________________________________________________________________________|____________|
   Stomach                                 | +     +     +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    | +     +     +  +  +  +  +  +                                             |  50        |
      Hyperplasia, Focal, Squamous         |                                                                          |      1  3.0|
      Inflammation, Chronic, Focal         |                                                                          |      3  2.7|
      Ulcer                                |                      2                                                   |      1  2.0|
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      | +     +     +  +  +  +  +  +                                             |  50        |
      Erosion                              |                                                                          |      1  3.0|
      Ulcer                                |                                                                          |      2  3.0|
                                            __________________________________________________________________________|____________|
   Tongue                                  |                                                                          |   1        |
      Epithelium, Hyperplasia, Focal       |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Tooth                                   |                                                                          |   3        |
      Inflammation, Chronic                |                                                                          |      2  3.0|
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Heart                                   | +     +     +  +  +  +  +  +                                             |  50        |
      Inflammation, Chronic, Focal         |       2     2  2  2  1                                                   |     28  2.0|
      Thrombosis                           | X                                                                        |      1     |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           | +     +     +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   | +     +     +  +  +  +  +  +                                             |  50        |
      Angiectasis                          |                                                                          |      3  2.3|
      Cytoplasmic Alteration, Focal        |                                                                          |      1  2.0|
      Degeneration, Fatty, Focal           | 2     2                    2                                             |     15  2.0|
      Hemorrhage, Focal                    |                                                                          |      1  3.0|
      Hyperplasia, Focal                   | 2           2  1                                                         |     13  2.4|
      Mineralization, Focal                |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  | +     +     +  +  +  +  +  +                                             |  49        |
      Hyperplasia                          | 1     2              1  1                                                |     15  1.4|
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      | +     +     +  +  +  +  +  +                                             |  47        |
      Hyperplasia, Focal                   |                                                                          |      2  2.5|
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       | M     +     +  +  +  +  +  +                                             |  39        |
      Hyperplasia, Focal                   |                                                                          |      1  3.0|
      Hypoplasia, Diffuse                  |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         | +  +  +     +  +  +  +  +  +                                             |  51        |
      Angiectasis                          |                                                                          |      6  3.2|
      Cyst                                 |                   X                                                      |     23     |
      Cyst, Multiple                       |                                                                          |      3     |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  26                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 __________________________________________________________________________________________________________________________________ 
                                           | 6| 4| 7| 4| 7| 7| 7| 6| 6| 6|                                            |            |
                             DAY ON TEST   | 5| 5| 3| 5| 2| 3| 3| 9| 8| 8|                                            |            |
                                           | 6| 7| 0| 7| 9| 0| 0| 9| 0| 1|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|                                            |      A     |
    50 MG/KG                               | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|                                            |      L     |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
      Pigmentation, Focal                  |                                                                          |      1  3.0|
      Pars Distalis, Angiectasis, Focal    |                                                                          |      3  3.0|
      Pars Distalis, Hyperplasia, Focal    |                                                                          |      8  2.3|
      Pars Distalis, Metaplasia, Focal,    |                                                                          |            |
           Osseous                         |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           | M     +     +  +  +  +  +  +                                             |  49        |
      Hemorrhage, Multifocal               |                                                                          |      1  2.0|
      C-Cell, Hyperplasia, Focal           |                   1        1                                             |     12  1.5|
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Clitoral Gland                          | M     M     +  +  +  M  M  M                                             |  41        |
      Atrophy                              |                                                                          |      1  4.0|
      Hyperplasia, Focal                   |                                                                          |      3  2.7|
      Inflammation, Chronic, Focal         |                                                                          |      4  2.3|
                                            __________________________________________________________________________|____________|
   Ovary                                   | +     +     +  +  +  +  +  +                                             |  50        |
      Congestion                           |                                                                          |      2  2.0|
      Cyst                                 |                   X        X                                             |      5     |
      Granuloma, Focal                     |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Uterus                                  | +     +     +  +  +  +  +  +                                             |  52        |
      Dilatation                           |                                                                          |      2  2.5|
      Fibrosis                             |                                                                          |      2  4.0|
      Hydrometra                           |                                                                          |      1  4.0|
      Cervix, Fibrosis                     |                                                                          |      1  4.0|
      Lumen, Hemorrhage                    |                                                                          |      1  4.0|
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             | +     +     +  +  +  +  +  +                                             |  50        |
      Myelofibrosis, Focal                 | 2                                                                        |      1  2.0|
                                            __________________________________________________________________________|____________|
   Lymph Node                              | +     +     +  +  +  +  +  +                                             |  50        |
      Iliac, Ectasia                       |                         2                                                |      1  2.0|
      Iliac, Infiltration Cellular,        |                                                                          |            |
          Histiocyte                       |                         3                                                |      1  3.0|
      Mandibular, Congestion               |                                                                          |      1  3.0|
      Mandibular, Hyperplasia, Plasma Cell |                                                                          |      1  2.0|
      Mediastinal, Congestion              |                                                                          |      2  2.5|
      Mediastinal, Hyperplasia, Lymphoid   | 3                                                                        |      1  3.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  27                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 __________________________________________________________________________________________________________________________________ 
                                           | 6| 4| 7| 4| 7| 7| 7| 6| 6| 6|                                            |            |
                             DAY ON TEST   | 5| 5| 3| 5| 2| 3| 3| 9| 8| 8|                                            |            |
                                           | 6| 7| 0| 7| 9| 0| 0| 9| 0| 1|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|                                            |      A     |
    50 MG/KG                               | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|                                            |      L     |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
      Mediastinal, Hyperplasia, Plasma Cell|                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  | +     +     +  +  +  +  +  +                                             |  50        |
      Congestion                           |                                                                          |      1  3.0|
      Fibrosis, Focal                      |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Spleen                                  | +     +     +  +  +  +  +  +                                             |  50        |
      Hematopoietic Cell Proliferation     |                                                                          |      2  3.0|
                                            __________________________________________________________________________|____________|
   Thymus                                  | M     +     +  +  +  +  +  +                                             |  45        |
      Cyst                                 |                                                                          |      1     |
      Cyst, Multiple                       |       X                                                                  |      2     |
      Hemorrhage                           |                                                                          |      1  3.0|
      Mediastinum, Inflammation, Acute     |                                                                          |      1  3.0|
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           | +     +     +  +  +  +  +  +                                             |  50        |
      Galactocele                          |       X                                                                  |      1     |
      Galactocele, Multiple                |                         X                                                |      1     |
                                            __________________________________________________________________________|____________|
   Skin                                    | +     +     +  +  +  +  +  +                                             |  50        |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    | +     +     +  +  +  +  +  +                                             |  50        |
      Cranium, Hyperostosis                |                                                                          |      1     |
      Femur, Hyperostosis                  |                                                                          |      3     |
      Femur, Osteopetrosis                 |                                                                          |      2  4.0|
      Turbinate, Hyperostosis              |                                                                          |      2     |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   | +     +     +  +  +  +  +  +                                             |  50        |
      Hemorrhage, Focal                    |                            1                                             |      3  2.0|
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lung                                    | +     +     +  +  +  +  +  +                                             |  50        |
      Congestion                           |             2                                                            |     12  2.4|
      Emphysema, Focal                     |                                                                          |      1  2.0|
      Hemorrhage, Focal                    |                                                                          |      1  2.0|
      Hyperplasia, Focal                   |                                                                          |      4  2.0|
      Inflammation, Chronic, Focal         |                            3                                             |      3  1.7|
                                            __________________________________________________________________________|____________|
   Nose                                    | +     +     +  +  +  +  +  +                                             |  50        |
      Foreign Body                         |                                                                          |      1  1.0|
      Fungus                               |                                                                          |      2     |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  28                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 __________________________________________________________________________________________________________________________________ 
                                           | 6| 4| 7| 4| 7| 7| 7| 6| 6| 6|                                            |            |
                             DAY ON TEST   | 5| 5| 3| 5| 2| 3| 3| 9| 8| 8|                                            |            |
                                           | 6| 7| 0| 7| 9| 0| 0| 9| 0| 1|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|                                            |      A     |
    50 MG/KG                               | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|                                            |      L     |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 RESPIRATORY SYSTEM - cont                 |                                                                          |            |
                                           |                                                                          |            |
      Inflammation, Chronic, Focal         |                                                                          |      1  3.0|
      Inflammation, Focal, Suppurative     |                                                                          |      2  1.5|
                                            __________________________________________________________________________|____________|
   Trachea                                 | +     +     +  +  +  +  +  +                                             |  50        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Eye                                     |                   +                                                      |   7        |
      Atrophy                              |                                                                          |      2  4.0|
      Synechia                             |                                                                          |      2  3.0|
      Lens, Cataract                       |                                                                          |      5  2.6|
      Retina, Degeneration                 |                   4                                                      |      5  4.0|
                                            __________________________________________________________________________|____________|
   Harderian Gland                         |                                                                          |   1        |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  | +     +     +  +  +  +  +  +                                             |  50        |
      Congestion                           |                                                                          |      2  2.5|
      Cyst                                 |                                                                          |      1     |
      Hemorrhage, Focal                    |                                                                          |      1  2.0|
      Nephropathy, Chronic                 | 4     4     2  2  3  4  3  3                                             |     47  2.5|
      Pigmentation                         |                                                                          |      2  3.0|
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         | +     +     M  +  +  +  +  +                                             |  49        |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  29                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 7| 5| 7| 4| 7| 7| 7| 7| 7| 7| 4| 7| 6| 7| 4| 7| 7| 6| 7| 7| 7| 4| 6| 7| 6|             
                             DAY ON TEST   | 3| 7| 1| 5| 3| 2| 3| 3| 3| 3| 5| 3| 4| 2| 5| 2| 3| 2| 3| 3| 2| 6| 0| 3| 2|             
                                           | 0| 9| 6| 7| 1| 9| 1| 0| 0| 1| 7| 0| 6| 9| 7| 9| 0| 7| 0| 0| 9| 3| 8| 1| 7|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    100 MG/K                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  M  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  A|             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
      Parasite Metazoan                    |                                                                         X|             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
      Angiectasis, Focal                   |                   2                          2  2        2               |             
      Basophilic Focus                     |                X     X                                X  X               |             
      Basophilic Focus, Multiple           | X     X     X     X     X        X  X        X              X            |             
      Clear Cell Focus                     |                                                                          |             
      Clear Cell Focus, Multiple           |                                        X                                 |             
      Cytoplasmic Alteration, Focal        | 2                                                                        |             
      Fibrosis, Focal                      |                                  1                                       |             
      Hepatodiaphragmatic Nodule           | X                 X     X                          X                     |             
      Hepatodiaphragmatic Nodule, Multiple |                                                 X                        |             
      Inflammation, Chronic, Focal         |             3  2  2  3           3     1     1        2  1  2     1      |             
      Necrosis, Focal                      |                                                                          |             
      Pigmentation                         |                            3                                             |             
      Bile Duct, Hyperplasia               |    4  1     2  1  1  2  2              1     1        1  1  2            |             
      Centrilobular, Fatty Change          |    3                       3                                             |             
      Periportal, Fatty Change             |                                                                          |             
      Serosa, Inflammation, Chronic, Focal |                                                                          |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                                                          |             
      Fat, Necrosis                        |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
      Atrophy, Focal                       |                         2                       2  2  1  2           2   |             
      Inflammation, Chronic, Focal         |                                                                          |             
      Artery, Inflammation, Chronic, Focal |                                              3                           |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +  +  +     +  +  +  +  M  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
      Atrophy                              |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +     +  +  +  +  +  +     +  M  +     +  +  +  +  +  I  +  +  +  +|             
      Hyperplasia, Diffuse, Squamous       | 4                                                                        |             
      Hyperplasia, Focal, Squamous         |                                                                          |             
      Inflammation, Chronic, Diffuse       | 4                                                                        |             
      Inflammation, Chronic, Focal         |                                                                          |             
      Mineralization                       |                                                                2         |             
      Ulcer                                |                                                                2         |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page  30                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 7| 5| 7| 4| 7| 7| 7| 7| 7| 7| 4| 7| 6| 7| 4| 7| 7| 6| 7| 7| 7| 4| 6| 7| 6|             
                             DAY ON TEST   | 3| 7| 1| 5| 3| 2| 3| 3| 3| 3| 5| 3| 4| 2| 5| 2| 3| 2| 3| 3| 2| 6| 0| 3| 2|             
                                           | 0| 9| 6| 7| 1| 9| 1| 0| 0| 1| 7| 0| 6| 9| 7| 9| 0| 7| 0| 0| 9| 3| 8| 1| 7|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    100 MG/K                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
      Erosion                              |    2                                                                    1|             
      Mineralization                       |                                              4                           |             
      Ulcer                                |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
      Inflammation, Chronic, Focal         |       2     2  2     2              2  2     3  2     2     1     2  2   |             
      Mineralization, Multifocal           |                                              2                           |             
      Atrium, Thrombosis                   |                                                                X         |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
      Angiectasis                          |                                                                          |             
      Atrophy, Diffuse                     |                            3                                             |             
      Congestion                           |                                                                4         |             
      Cytoplasmic Alteration, Focal        |                                                                          |             
      Degeneration, Fatty, Focal           | 2  2        2     2  1           3  2        2     3  2        2         |             
      Hyperplasia, Focal                   | 1                    2  1           1                                    |             
      Hypertrophy, Focal                   |                                                                      2   |             
      Pigmentation                         |                            3                                             |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +        +  +  +  +  +     +  +  +     +  M  +  +  +  +  +  M  +  +|             
      Hematocyst                           |                                                       X                  |             
      Hyperplasia                          |                   1        4        1  3     1     2     1           1   |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  M  +  I  M  +  +  +|             
      Hyperplasia, Diffuse                 |                                              4                           |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
      Angiectasis                          |    3        3           3        2                    3                  |             
      Cyst                                 |    X        X  X  X     X        X     X        X  X  X  X  X  X  X  X   |             
      Cyst, Multiple                       |                                                                         X|             
      Pars Distalis, Angiectasis, Focal    |                                                                          |             
      Pars Distalis, Hyperplasia, Focal    |             2        2     1                          2        2         |             
      Pars Distalis, Hypoplasia            |                            3                                             |             
      Pars Nervosa, Metaplasia, Focal,     |                                                                          |             
           Osseous                         |                                                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
      C-Cell, Hyperplasia, Focal           |                   1                    1                       1         |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Clitoral Gland                          | +  +  M     M  +  +  +  +  M     +  +  +     +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page  31                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 7| 5| 7| 4| 7| 7| 7| 7| 7| 7| 4| 7| 6| 7| 4| 7| 7| 6| 7| 7| 7| 4| 6| 7| 6|             
                             DAY ON TEST   | 3| 7| 1| 5| 3| 2| 3| 3| 3| 3| 5| 3| 4| 2| 5| 2| 3| 2| 3| 3| 2| 6| 0| 3| 2|             
                                           | 0| 9| 6| 7| 1| 9| 1| 0| 0| 1| 7| 0| 6| 9| 7| 9| 0| 7| 0| 0| 9| 3| 8| 1| 7|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    100 MG/K                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
      Concretion                           |                2                                                         |             
      Dilatation                           |                                                                4         |             
      Hyperplasia, Focal                   |                                                                          |             
      Inflammation, Chronic, Focal         |                                                                          |             
                                            __________________________________________________________________________|             
   Ovary                                   | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
      Cyst                                 |                                                             X            |             
                                            __________________________________________________________________________|             
   Uterus                                  | +  +  +  +  +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
      Dilatation                           |                                                                          |             
      Hyperplasia, Chronic, Cystic         |                                                                          |             
      Hyperplasia, Cystic                  |          2                                                               |             
      Lumen, Hemorrhage                    |                                                                          |             
                                            __________________________________________________________________________|             
   Vagina                                  |                                                                +         |             
      Inflammation, Subacute               |                                                                4         |             
      Necrosis, Acute, Diffuse             |                                                                4         |             
      Prolapse                             |                                                                X         |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
      Myelofibrosis, Focal                 |                                     2        4                           |             
      Erythroid Cell, Proliferation        |                                                                4         |             
      Myeloid Cell, Proliferation          |    3                                                                     |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
      Axillary, Infiltration Cellular,     |                                                                          |             
           Histiocyte                      |                                                                          |             
      Inguinal, Ectasia                    |                                     2                                    |             
      Inguinal, Hyperplasia, Lymphoid      |                                     4                                    |             
      Inguinal, Hyperplasia, Plasma Cell   |                                     4                                    |             
      Mandibular, Hyperplasia, Plasma Cell |                                     4                                    |             
      Mediastinal, Pigmentation            |                                        3                                 |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
      Hemorrhage                           |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
      Congestion, Focal                    |                                                                2         |             
      Fibrosis, Focal                      |                            4                                             |             
      Hematopoietic Cell Proliferation     |                                                                          |             
      Thrombosis                           |                                     X                                    |             
                                            __________________________________________________________________________|             
   Thymus                                  | +  +  +     +  +  +  +  +  +     +  +  +     +  M  +  +  +  +  +  +  +  +|             
      Cyst                                 |                   X                                                      |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
      Hyperplasia, Cystic, Glandular       |                         2  3                                             |             
      Mineralization                       |                                              4                           |             
                                            __________________________________________________________________________|             
   Skin                                    | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page  32                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 7| 5| 7| 4| 7| 7| 7| 7| 7| 7| 4| 7| 6| 7| 4| 7| 7| 6| 7| 7| 7| 4| 6| 7| 6|             
                             DAY ON TEST   | 3| 7| 1| 5| 3| 2| 3| 3| 3| 3| 5| 3| 4| 2| 5| 2| 3| 2| 3| 3| 2| 6| 0| 3| 2|             
                                           | 0| 9| 6| 7| 1| 9| 1| 0| 0| 1| 7| 0| 6| 9| 7| 9| 0| 7| 0| 0| 9| 3| 8| 1| 7|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    100 MG/K                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Developmental Malformation           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
      Femur, Fibrous Osteodystrophy        |                                              X                           |             
      Femur, Hyperostosis                  |                                                                          |             
      Maxilla, Hyperostosis                |                                                                          |             
      Turbinate, Hyperostosis              |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
      Congestion, Diffuse                  |                                                                          |             
      Congestion                           | 2                                            4  2              3  3      |             
      Foreign Body                         |                                                    2                     |             
      Granuloma, Focal                     |                                                    3                     |             
      Hemorrhage, Focal                    |                                                                          |             
      Hyperplasia, Focal                   | 2           1                       2                                    |             
      Inflammation, Chronic, Diffuse       |                                              3                           |             
      Inflammation, Chronic, Focal         |                                                    3                     |             
      Metaplasia, Focal, Osseous           |                                                                          |             
      Interstitium, Mineralization, Diffuse|                                              3                           |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
      Foreign Body                         |                                                    3     2               |             
      Fungus                               |                                                                          |             
      Inflammation, Acute, Focal           |                                                    3     2               |             
      Inflammation, Acute                  |                                                                          |             
      Inflammation, Chronic, Focal         |                                                                          |             
      Metaplasia, Squamous                 |                                                                          |             
      Nasolacrimal Duct, Inflammation,     |                                                                          |             
           Chronic                         |             3                                                            |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |                                                                          |             
      Lens, Cataract                       |                                                                          |             
                                            __________________________________________________________________________|             
   Zymbal's Gland                          |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
      Congestion                           |       3                                                                  |             
      Cyst                                 | X                       X                                                |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  33                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 7| 5| 7| 4| 7| 7| 7| 7| 7| 7| 4| 7| 6| 7| 4| 7| 7| 6| 7| 7| 7| 4| 6| 7| 6|             
                             DAY ON TEST   | 3| 7| 1| 5| 3| 2| 3| 3| 3| 3| 5| 3| 4| 2| 5| 2| 3| 2| 3| 3| 2| 6| 0| 3| 2|             
                                           | 0| 9| 6| 7| 1| 9| 1| 0| 0| 1| 7| 0| 6| 9| 7| 9| 0| 7| 0| 0| 9| 3| 8| 1| 7|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    100 MG/K                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
      Degeneration, Diffuse, Hyaline       |                                     3                                    |             
      Mineralization                       |                                              4                           |             
      Nephropathy, Chronic                 | 4  1  1     2  2  2  3  3  2     3     4     4  1  3  3  3  2  1  1  2   |             
      Pigmentation                         |                            4                                         3   |             
      Pelvis, Mineralization               |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +     +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +|             
      Inflammation, Chronic, Focal         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  34                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 6| 4| 4| 7| 7| 6| 6| 6| 6| 7| 7| 6| 5| 4| 4| 6| 4| 4| 6| 7| 7| 4| 7|             
                             DAY ON TEST   | 5| 0| 7| 5| 5| 3| 2| 7| 6| 3| 8| 1| 3| 2| 2| 3| 5| 8| 5| 5| 6| 2| 3| 5| 2|             
                                           | 7| 2| 8| 5| 7| 1| 9| 3| 2| 7| 9| 6| 1| 3| 4| 0| 7| 8| 7| 7| 6| 9| 1| 7| 9|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    100 MG/K                               | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     M|             
                                            __________________________________________________________________________|             
   Intestine Large                         |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
      Parasite Metazoan                    |          X                                                              X|             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
                                            __________________________________________________________________________|             
   Intestine Small                         |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               |    +  +  +     +  +  +  +  +  +  +  +  +  +  +              +  +  +     +|             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  |    +  +  +     +  +  +  +  +  +  +  +  +  +  +              +  +  +     +|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                |    +  +  +     +  +  +  +  +  M  +  +  +  +  +     +        +  +  +     +|             
                                            __________________________________________________________________________|             
   Liver                                   |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
      Angiectasis, Focal                   |                                                                          |             
      Basophilic Focus                     |    X     X        X                 X                       X            |             
      Basophilic Focus, Multiple           |                X     X     X                                      X     X|             
      Clear Cell Focus                     |                                                                          |             
      Clear Cell Focus, Multiple           |                                                                   X      |             
      Cytoplasmic Alteration, Focal        |                                                                          |             
      Fibrosis, Focal                      |                                                                          |             
      Hepatodiaphragmatic Nodule           |                      X                                         X         |             
      Hepatodiaphragmatic Nodule, Multiple |                                                                          |             
      Inflammation, Chronic, Focal         |    2  1        1  3  2  1  2        1                       1     3     3|             
      Necrosis, Focal                      |                                                                2         |             
      Pigmentation                         |                                                                          |             
      Bile Duct, Hyperplasia               |    1  1        2  1  1     3                       2        2           1|             
      Centrilobular, Fatty Change          |                               4                    4                     |             
      Periportal, Fatty Change             |                         3                                                |             
      Serosa, Inflammation, Chronic, Focal |                                                                2         |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                     +                                    |             
      Fat, Necrosis                        |                                     3                                    |             
                                            __________________________________________________________________________|             
   Pancreas                                |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
      Atrophy, Focal                       |                3  1     1              1  1                 2           1|             
      Inflammation, Chronic, Focal         |                                                                          |             
      Artery, Inflammation, Chronic, Focal |                                                                          |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |    M  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
      Atrophy                              |                         3     4                                          |             
                                            __________________________________________________________________________|             
   Stomach                                 |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
      Hyperplasia, Diffuse, Squamous       |                         3                                                |             
      Hyperplasia, Focal, Squamous         |                                           2                              |             
      Inflammation, Chronic, Diffuse       |                         3                                                |             
      Inflammation, Chronic, Focal         |                                           2                              |             
      Mineralization                       |                                                                          |             
      Ulcer                                |                         2                                                |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page  35                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 6| 4| 4| 7| 7| 6| 6| 6| 6| 7| 7| 6| 5| 4| 4| 6| 4| 4| 6| 7| 7| 4| 7|             
                             DAY ON TEST   | 5| 0| 7| 5| 5| 3| 2| 7| 6| 3| 8| 1| 3| 2| 2| 3| 5| 8| 5| 5| 6| 2| 3| 5| 2|             
                                           | 7| 2| 8| 5| 7| 1| 9| 3| 2| 7| 9| 6| 1| 3| 4| 0| 7| 8| 7| 7| 6| 9| 1| 7| 9|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    100 MG/K                               | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
      Erosion                              |                                                                          |             
      Mineralization                       |                                                                          |             
      Ulcer                                |                                           2                              |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
      Inflammation, Chronic, Focal         |                2  2  1  2  1        2  2  1                 2  2  2     2|             
      Mineralization, Multifocal           |                                                                          |             
      Atrium, Thrombosis                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
      Angiectasis                          |                3                       3                                 |             
      Atrophy, Diffuse                     |                                                                          |             
      Congestion                           |                                                                          |             
      Cytoplasmic Alteration, Focal        |                            1                                             |             
      Degeneration, Fatty, Focal           |       1        2  3  2     1  3        2                          2     1|             
      Hyperplasia, Focal                   |                                     2  2                                 |             
      Hypertrophy, Focal                   |                                                                          |             
      Pigmentation                         |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  |    +  +  +     +  +  +  +  +  +  +  +  +  +  M     M        +  +  +     +|             
      Hematocyst                           |                                                                          |             
      Hyperplasia                          |                                     1  2                    1           1|             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      |    +  +  +     +  +  +  +  +  I  +  +  +  +  +     +        +  +  +     +|             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       |    M  +  +     +  +  M  +  +  +  +  +  +  +  +     M        M  +  +     +|             
      Hyperplasia, Diffuse                 |                                                                          |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
      Angiectasis                          |                            3                                             |             
      Cyst                                 |                               X                                          |             
      Cyst, Multiple                       |                X                 X  X                          X  X     X|             
      Pars Distalis, Angiectasis, Focal    |                                                                          |             
      Pars Distalis, Hyperplasia, Focal    |       2                       3     2              2           2         |             
      Pars Distalis, Hypoplasia            |                                                                          |             
      Pars Nervosa, Metaplasia, Focal,     |                                                                          |             
           Osseous                         |                   4                                                      |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
      C-Cell, Hyperplasia, Focal           |       1                    1                       1        2  2         |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Clitoral Gland                          |    M  +  +     +  +  M  +  M  +  +  +  +  +  +     M        +  +  +     +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page  36                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 6| 4| 4| 7| 7| 6| 6| 6| 6| 7| 7| 6| 5| 4| 4| 6| 4| 4| 6| 7| 7| 4| 7|             
                             DAY ON TEST   | 5| 0| 7| 5| 5| 3| 2| 7| 6| 3| 8| 1| 3| 2| 2| 3| 5| 8| 5| 5| 6| 2| 3| 5| 2|             
                                           | 7| 2| 8| 5| 7| 1| 9| 3| 2| 7| 9| 6| 1| 3| 4| 0| 7| 8| 7| 7| 6| 9| 1| 7| 9|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    100 MG/K                               | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
      Concretion                           |                                                                          |             
      Dilatation                           |                                                                          |             
      Hyperplasia, Focal                   |                                                                          |             
      Inflammation, Chronic, Focal         |                2                                                         |             
                                            __________________________________________________________________________|             
   Ovary                                   |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
      Cyst                                 |                                           X                    X         |             
                                            __________________________________________________________________________|             
   Uterus                                  |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
      Dilatation                           |                                                                          |             
      Hyperplasia, Chronic, Cystic         |                                                                3         |             
      Hyperplasia, Cystic                  |                                                                          |             
      Lumen, Hemorrhage                    |                3                                                         |             
                                            __________________________________________________________________________|             
   Vagina                                  |                                                                          |             
      Inflammation, Subacute               |                                                                          |             
      Necrosis, Acute, Diffuse             |                                                                          |             
      Prolapse                             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
      Myelofibrosis, Focal                 |                                                                   1      |             
      Erythroid Cell, Proliferation        |       3                                4                                 |             
      Myeloid Cell, Proliferation          |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
      Axillary, Infiltration Cellular,     |                                                                          |             
           Histiocyte                      |    2                                                                     |             
      Inguinal, Ectasia                    |                                        3                                 |             
      Inguinal, Hyperplasia, Lymphoid      |                                                                          |             
      Inguinal, Hyperplasia, Plasma Cell   |                                                                          |             
      Mandibular, Hyperplasia, Plasma Cell |                            4                                             |             
      Mediastinal, Pigmentation            |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |    +  +  +     +  +  +  +  +  +  +  +  +  +  +              +  +  +     +|             
      Hemorrhage                           |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
      Congestion, Focal                    |                                                                          |             
      Fibrosis, Focal                      | 2                                                                        |             
      Hematopoietic Cell Proliferation     |       3  2                             4                                 |             
      Thrombosis                           |                                                                          |             
                                            __________________________________________________________________________|             
   Thymus                                  |    +  +  +     +  +  M  +  +  +  +  +  +  +  +     +        +  +  +     +|             
      Cyst                                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
      Hyperplasia, Cystic, Glandular       |                                                                          |             
      Mineralization                       |                                                                          |             
                                            __________________________________________________________________________|             
   Skin                                    |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +     +  +  +  +     +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page  37                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 6| 4| 4| 7| 7| 6| 6| 6| 6| 7| 7| 6| 5| 4| 4| 6| 4| 4| 6| 7| 7| 4| 7|             
                             DAY ON TEST   | 5| 0| 7| 5| 5| 3| 2| 7| 6| 3| 8| 1| 3| 2| 2| 3| 5| 8| 5| 5| 6| 2| 3| 5| 2|             
                                           | 7| 2| 8| 5| 7| 1| 9| 3| 2| 7| 9| 6| 1| 3| 4| 0| 7| 8| 7| 7| 6| 9| 1| 7| 9|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    100 MG/K                               | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Developmental Malformation           |                                     X                                    |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
      Femur, Fibrous Osteodystrophy        |                                                                          |             
      Femur, Hyperostosis                  |                   X                                                      |             
      Maxilla, Hyperostosis                |                   X                                                      |             
      Turbinate, Hyperostosis              |                   X                                                      |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +  +  +|             
      Congestion, Diffuse                  |                                                                      3   |             
      Congestion                           |          3                    2              3                          2|             
      Foreign Body                         |                                                                          |             
      Granuloma, Focal                     |                   1  1                                                   |             
      Hemorrhage, Focal                    |                                                                          |             
      Hyperplasia, Focal                   |                                                                2         |             
      Inflammation, Chronic, Diffuse       |                                                                          |             
      Inflammation, Chronic, Focal         |                                                                          |             
      Metaplasia, Focal, Osseous           |                   3                                                      |             
      Interstitium, Mineralization, Diffuse|                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
      Foreign Body                         |                                                                          |             
      Fungus                               |                                                                          |             
      Inflammation, Acute, Focal           |                                                                          |             
      Inflammation, Acute                  |                                                                          |             
      Inflammation, Chronic, Focal         |                      2                                                   |             
      Metaplasia, Squamous                 |                                                                          |             
      Nasolacrimal Duct, Inflammation,     |                                                                          |             
           Chronic                         |                                                                          |             
                                            __________________________________________________________________________|             
   Trachea                                 |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |                                                                          |             
      Lens, Cataract                       |                                                                          |             
                                            __________________________________________________________________________|             
   Zymbal's Gland                          |       +                    +                                             |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  |    +  +  +     +  +  +  +  +  +  +  +  +  +  +     +        +  +  +     +|             
      Congestion                           |    3                                                                     |             
      Cyst                                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  38                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 6| 4| 4| 7| 7| 6| 6| 6| 6| 7| 7| 6| 5| 4| 4| 6| 4| 4| 6| 7| 7| 4| 7|             
                             DAY ON TEST   | 5| 0| 7| 5| 5| 3| 2| 7| 6| 3| 8| 1| 3| 2| 2| 3| 5| 8| 5| 5| 6| 2| 3| 5| 2|             
                                           | 7| 2| 8| 5| 7| 1| 9| 3| 2| 7| 9| 6| 1| 3| 4| 0| 7| 8| 7| 7| 6| 9| 1| 7| 9|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    100 MG/K                               | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
      Degeneration, Diffuse, Hyaline       |                                                                          |             
      Mineralization                       |                                                                          |             
      Nephropathy, Chronic                 |    3  1  1     2  2  2  4  1  1  2  1  1  2  2     2        2  2  2     3|             
      Pigmentation                         |                                                    4                     |             
      Pelvis, Mineralization               |                                              1                           |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         |    +  +  +     +  +  +  M  M  +  +  +  +  +  +     +        +  +  +     +|             
      Inflammation, Chronic, Focal         |                   3                                                      |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  39                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 6| 4| 7| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 3| 2| 2| 7| 5| 3| 2| 2| 3| 1|                                            |            |
                                           | 0| 9| 9| 4| 7| 1| 9| 9| 1| 2|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|                                            |      A     |
    100 MG/K                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      L     |
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               | +  +  +  +     +  M  +  +  M                                             |  46        |
                                            __________________________________________________________________________|____________|
   Intestine Large                         | +  +  +  +     +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +  +  +  +     +  +  +  +  +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  | +  +  +  +     +  +  +  +  +                                             |  50        |
      Parasite Metazoan                    |                      X                                                   |      4     |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +  +  +  +     +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Small                         | +  +  +  +     +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  +  +  +     +  +  +  +  +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  +  +  +     +  +  +  +  +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +  +  +  +     +  +  +  +  +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Liver                                   | +  +  +  +     +  +  +  +  +                                             |  50        |
      Angiectasis, Focal                   |                1                                                         |      5  1.8|
      Basophilic Focus                     | X     X                                                                  |     11     |
      Basophilic Focus, Multiple           |    X           X  X  X  X                                                |     19     |
      Clear Cell Focus                     |    X                                                                     |      1     |
      Clear Cell Focus, Multiple           |                         X                                                |      3     |
      Cytoplasmic Alteration, Focal        |                                                                          |      1  2.0|
      Fibrosis, Focal                      |                                                                          |      1  1.0|
      Hepatodiaphragmatic Nodule           |       X                                                                  |      7     |
      Hepatodiaphragmatic Nodule, Multiple |                                                                          |      1     |
      Inflammation, Chronic, Focal         | 2  1  2        2  1  2  1                                                |     29  1.8|
      Necrosis, Focal                      |                                                                          |      1  2.0|
      Pigmentation                         |                                                                          |      1  3.0|
      Bile Duct, Hyperplasia               | 2  2           1  1  2                                                   |     26  1.6|
      Centrilobular, Fatty Change          |          4                                                               |      5  3.6|
      Periportal, Fatty Change             |                                                                          |      1  3.0|
      Serosa, Inflammation, Chronic, Focal |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Mesentery                               |                         +                                                |   2        |
      Fat, Necrosis                        |                         4                                                |      2  3.5|
                                            __________________________________________________________________________|____________|
   Pancreas                                | +  +  +  +     +  +  +  +  +                                             |  50        |
      Atrophy, Focal                       | 4  3  1  2     2  1                                                      |     19  1.8|
      Inflammation, Chronic, Focal         | 3                                                                        |      1  3.0|
      Artery, Inflammation, Chronic, Focal |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Salivary Glands                         | +  +  +  +     +  +  +  +  +                                             |  48        |
      Atrophy                              |                                                                          |      2  3.5|
                                            __________________________________________________________________________|____________|
   Stomach                                 | +  +  +  +     +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    | +  +  +  +     +  +  +  +  +                                             |  48        |
      Hyperplasia, Diffuse, Squamous       |                                                                          |      2  3.5|
      Hyperplasia, Focal, Squamous         |                                                                          |      1  2.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  40                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 6| 4| 7| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 3| 2| 2| 7| 5| 3| 2| 2| 3| 1|                                            |            |
                                           | 0| 9| 9| 4| 7| 1| 9| 9| 1| 2|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|                                            |      A     |
    100 MG/K                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      L     |
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM - cont                  |                                                                          |            |
                                           |                                                                          |            |
      Inflammation, Chronic, Diffuse       |                                                                          |      2  3.5|
      Inflammation, Chronic, Focal         |                                                                          |      1  2.0|
      Mineralization                       |                                                                          |      1  2.0|
      Ulcer                                |                                                                          |      2  2.0|
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +  +  +     +  +  +  +  +                                             |  50        |
      Erosion                              |                                                                          |      2  1.5|
      Mineralization                       |                                                                          |      1  4.0|
      Ulcer                                |                                                                          |      1  2.0|
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Heart                                   | +  +  +  +     +  +  +  +  +                                             |  50        |
      Inflammation, Chronic, Focal         |    2  1           1  2  2                                                |     29  1.8|
      Mineralization, Multifocal           |                                                                          |      1  2.0|
      Atrium, Thrombosis                   |                                                                          |      1     |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           | +  +  +  +     +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   | +  +  +  +     +  +  +  +  +                                             |  50        |
      Angiectasis                          |                                                                          |      2  3.0|
      Atrophy, Diffuse                     |                                                                          |      1  3.0|
      Congestion                           |                                                                          |      1  4.0|
      Cytoplasmic Alteration, Focal        |                                                                          |      1  1.0|
      Degeneration, Fatty, Focal           |    2              2                                                      |     22  2.0|
      Hyperplasia, Focal                   |    1                                                                     |      7  1.4|
      Hypertrophy, Focal                   |    3           1                                                         |      3  2.0|
      Pigmentation                         |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  | +  +  +  +     +  +  +  +  +                                             |  45        |
      Hematocyst                           |                                                                          |      1     |
      Hyperplasia                          |    1     1                                                               |     14  1.5|
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      | +  +  +  +     +  +  +  +  +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       | +  +  +  +     +  +  +  +  M                                             |  42        |
      Hyperplasia, Diffuse                 |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +  +                                             |  52        |
      Angiectasis                          | 3                                                                        |      7  2.9|
      Cyst                                 |    X     X        X     X  X                                             |     21     |
      Cyst, Multiple                       | X              X                                                         |      9     |
      Pars Distalis, Angiectasis, Focal    |          2                                                               |      1  2.0|
      Pars Distalis, Hyperplasia, Focal    |       4                                                                  |     11  2.2|
      Pars Distalis, Hypoplasia            |                                                                          |      1  3.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  41                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 6| 4| 7| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 3| 2| 2| 7| 5| 3| 2| 2| 3| 1|                                            |            |
                                           | 0| 9| 9| 4| 7| 1| 9| 9| 1| 2|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|                                            |      A     |
    100 MG/K                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      L     |
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
      Pars Nervosa, Metaplasia, Focal,     |                                                                          |            |
           Osseous                         |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           | +  +  +  +     +  +  +  +  +                                             |  50        |
      C-Cell, Hyperplasia, Focal           |          1     3                                                         |     10  1.4|
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Clitoral Gland                          | +  +  +  M     +  +  +  +  +                                             |  42        |
      Concretion                           |                                                                          |      1  2.0|
      Dilatation                           |                                                                          |      1  4.0|
      Hyperplasia, Focal                   |                   2                                                      |      1  2.0|
      Inflammation, Chronic, Focal         |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Ovary                                   | +  +  +  M     +  +  +  +  +                                             |  49        |
      Cyst                                 | X                                                                        |      4     |
                                            __________________________________________________________________________|____________|
   Uterus                                  | +  +  +  +  +  +  +  +  +  +                                             |  52        |
      Dilatation                           |             3                                                            |      1  3.0|
      Hyperplasia, Chronic, Cystic         |                                                                          |      1  3.0|
      Hyperplasia, Cystic                  |                                                                          |      1  2.0|
      Lumen, Hemorrhage                    |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Vagina                                  |                                                                          |   1        |
      Inflammation, Subacute               |                                                                          |      1  4.0|
      Necrosis, Acute, Diffuse             |                                                                          |      1  4.0|
      Prolapse                             |                                                                          |      1     |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             | +  +  +  +     +  +  +  +  +                                             |  50        |
      Myelofibrosis, Focal                 |                                                                          |      3  2.3|
      Erythroid Cell, Proliferation        |                                                                          |      3  3.7|
      Myeloid Cell, Proliferation          |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Lymph Node                              | +  +  +  +     +  +  +  +  +                                             |  50        |
      Axillary, Infiltration Cellular,     |                                                                          |            |
           Histiocyte                      |                                                                          |      1  2.0|
      Inguinal, Ectasia                    |                                                                          |      2  2.5|
      Inguinal, Hyperplasia, Lymphoid      |                                                                          |      1  4.0|
      Inguinal, Hyperplasia, Plasma Cell   |                                                                          |      1  4.0|
      Mandibular, Hyperplasia, Plasma Cell |                                                                          |      2  4.0|
      Mediastinal, Pigmentation            |                                                                          |      1  3.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  42                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 6| 4| 7| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 3| 2| 2| 7| 5| 3| 2| 2| 3| 1|                                            |            |
                                           | 0| 9| 9| 4| 7| 1| 9| 9| 1| 2|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|                                            |      A     |
    100 MG/K                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      L     |
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  | M  +  +  +     +  +  +  +  +                                             |  48        |
      Hemorrhage                           |                         3                                                |      1  3.0|
                                            __________________________________________________________________________|____________|
   Spleen                                  | +  +  +  +     +  +  +  +  +                                             |  51        |
      Congestion, Focal                    |                                                                          |      1  2.0|
      Fibrosis, Focal                      |                                                                          |      2  3.0|
      Hematopoietic Cell Proliferation     |                                                                          |      3  3.0|
      Thrombosis                           |                                                                          |      1     |
                                            __________________________________________________________________________|____________|
   Thymus                                  | +  +  +  +     +  +  +  +  +                                             |  48        |
      Cyst                                 |                   X     X                                                |      3     |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           | +  +  +  +     +  +  +  +  +                                             |  50        |
      Hyperplasia, Cystic, Glandular       |                                                                          |      2  2.5|
      Mineralization                       |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Skin                                    | +  +  +  +     +  +  +  +  +                                             |  51        |
      Developmental Malformation           |                                                                          |      1     |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    | +  +  +  +     +  +  +  +  +                                             |  50        |
      Femur, Fibrous Osteodystrophy        |                                                                          |      1     |
      Femur, Hyperostosis                  |                                                                          |      1     |
      Maxilla, Hyperostosis                |                                                                          |      1     |
      Turbinate, Hyperostosis              |                                                                          |      1     |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   | +  +  +  +     +  +  +  +  +                                             |  50        |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lung                                    | +  +  +  +     +  +  +  +  +                                             |  51        |
      Congestion, Diffuse                  |                                                                          |      1  3.0|
      Congestion                           | 2                 1                                                      |     11  2.5|
      Foreign Body                         |                                                                          |      1  2.0|
      Granuloma, Focal                     |                                                                          |      3  1.7|
      Hemorrhage, Focal                    |          2                 3                                             |      2  2.5|
      Hyperplasia, Focal                   | 3                                                                        |      5  2.0|
      Inflammation, Chronic, Diffuse       |                                                                          |      1  3.0|
      Inflammation, Chronic, Focal         |                                                                          |      1  3.0|
      Metaplasia, Focal, Osseous           |                                                                          |      1  3.0|
      Interstitium, Mineralization, Diffuse|                                                                          |      1  3.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  43                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 6| 4| 7| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 3| 2| 2| 7| 5| 3| 2| 2| 3| 1|                                            |            |
                                           | 0| 9| 9| 4| 7| 1| 9| 9| 1| 2|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|                                            |      A     |
    100 MG/K                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      L     |
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 RESPIRATORY SYSTEM - cont                 |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Nose                                    | +  +  +  +     +  +  +  +  +                                             |  50        |
      Foreign Body                         |                                                                          |      2  2.5|
      Fungus                               |                X                                                         |      1     |
      Inflammation, Acute, Focal           |                                                                          |      2  2.5|
      Inflammation, Acute                  |                4                                                         |      1  4.0|
      Inflammation, Chronic, Focal         |                                                                          |      1  2.0|
      Metaplasia, Squamous                 |                3                                                         |      1  3.0|
      Nasolacrimal Duct, Inflammation,     |                                                                          |            |
           Chronic                         |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Trachea                                 | +  +  +  +     +  +  +  +  +                                             |  50        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Eye                                     |                      +                                                   |   1        |
      Lens, Cataract                       |                      3                                                   |      1  3.0|
                                            __________________________________________________________________________|____________|
   Zymbal's Gland                          |                                                                          |   2        |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  | +  +  +  +     +  +  +  +  +                                             |  50        |
      Congestion                           |                                                                          |      2  3.0|
      Cyst                                 |                                                                          |      2     |
      Degeneration, Diffuse, Hyaline       |                                                                          |      1  3.0|
      Mineralization                       |                                                                          |      1  4.0|
      Nephropathy, Chronic                 | 2  3  2  2     2  3  2  2  2                                             |     48  2.1|
      Pigmentation                         |          3                                                               |      4  3.5|
      Pelvis, Mineralization               |                                                                          |      1  1.0|
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         | +  +  +  +     +  +  +  +  +                                             |  48        |
      Inflammation, Chronic, Focal         |                                                                          |      1  3.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  44                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 7| 4| 7| 2| 5| 7| 3| 4| 7| 7| 3| 6| 7| 7| 3| 7| 6| 4| 7| 4| 4| 7| 4|             
                             DAY ON TEST   | 3| 1| 3| 4| 3| 1| 7| 3| 0| 5| 2| 3| 2| 7| 2| 2| 8| 3| 0| 5| 3| 5| 3| 3| 5|             
                                           | 1| 8| 1| 7| 0| 3| 3| 1| 3| 7| 9| 0| 3| 8| 9| 9| 6| 1| 1| 7| 1| 7| 4| 0| 7|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    150 MG/K                               | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
      Parasite Metazoan                    |                               X                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
      Parasite Metazoan                    |    X     X              X                                                |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
      Parasite Metazoan                    |          X                                            X           X      |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
      Angiectasis, Focal                   |                               2                                          |             
      Basophilic Focus                     |                   X              X                                X  X   |             
      Basophilic Focus, Multiple           | X  X     X  X        X        X        X  X  X              X            |             
      Clear Cell Focus                     |             X                                X     X  X              X   |             
      Clear Cell Focus, Multiple           |                                                                          |             
      Cytoplasmic Alteration, Focal        |                                                                          |             
      Granuloma, Focal                     |                                                                          |             
      Hematopoietic Cell Proliferation     |                                           2                              |             
      Hepatodiaphragmatic Nodule           |       X                       X                                          |             
      Inflammation, Chronic, Focal         | 3        1  2        2        3           4  3     3        1            |             
      Necrosis, Focal                      |                                                                          |             
      Bile Duct, Cyst                      |                                                    X                     |             
      Bile Duct, Hyperplasia               | 1  1  3  1  1        2        2  2     3  1  2     2        2        1   |             
      Centrilobular, Fatty Change          |                                                                          |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                                                          |             
      Fat, Necrosis                        |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
      Atrophy, Focal                       |       1           2  2                                      1        2   |             
      Hyperplasia, Focal                   |                                                             2            |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
      Cyst                                 |       X                                                                  |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
      Inflammation, Acute, Diffuse         |                                                                          |             
      Mineralization                       |                   2                                                      |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
      Erosion                              |                                                                          |             
      Inflammation, Acute, Focal           |                                                                   2      |             
      Mineralization                       |                   2                                                      |             
                                            __________________________________________________________________________|             
   Tooth                                   |                                                    +                     |             
      Inflammation, Chronic                |                                                    3                     |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  45                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 7| 4| 7| 2| 5| 7| 3| 4| 7| 7| 3| 6| 7| 7| 3| 7| 6| 4| 7| 4| 4| 7| 4|             
                             DAY ON TEST   | 3| 1| 3| 4| 3| 1| 7| 3| 0| 5| 2| 3| 2| 7| 2| 2| 8| 3| 0| 5| 3| 5| 3| 3| 5|             
                                           | 1| 8| 1| 7| 0| 3| 3| 1| 3| 7| 9| 0| 3| 8| 9| 9| 6| 1| 1| 7| 1| 7| 4| 0| 7|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    150 MG/K                               | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
      Inflammation, Chronic, Focal         |    2        2                 2  2        1  2              2        3   |             
      Mineralization, Multifocal           |                                                                          |             
      Artery, Hyperplasia, Focal           |                                                                          |             
      Artery, Mineralization               |                   3                                                      |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
      Degeneration, Diffuse, Fatty         |                                                                          |             
      Degeneration, Fatty, Focal           |    2                                   3                    3            |             
      Hyperplasia, Focal                   |             2                                      2                     |             
      Hypertrophy, Focal                   |                                              1                           |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
      Angiectasis                          |                                                             3            |             
      Hyperplasia                          |                      3                 2  3                              |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
      Hyperplasia, Focal                   |                                                                          |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +  +  M  +  +  M  +  +  M     M  +  +  +  +  +  +  +  M     +     +  M   |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +|             
      Angiectasis                          |       3     3                                                            |             
      Cyst                                 |       X     X                 X  X     X  X        X                     |             
      Cyst, Multiple                       |                                              X                           |             
      Pars Distalis, Angiectasis           |                                                                3         |             
      Pars Distalis, Hyperplasia, Focal    |                                        2                                 |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +     +  +   |             
      C-Cell, Hyperplasia, Focal           |       1                                                                  |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Clitoral Gland                          | +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +  +  +     +     +  +   |             
      Atrophy                              |       4                                                                  |             
      Dilatation                           |                                                             4            |             
      Hyperplasia, Focal                   |                            2                                             |             
      Inflammation, Chronic, Focal         |                                                                          |             
                                            __________________________________________________________________________|             
   Ovary                                   | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
      Cyst                                 |                                                                          |             
                                            __________________________________________________________________________|             
   Uterus                                  | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +   |             
      Dilatation                           |                                                                          |             
      Hydrometra                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  46                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 7| 4| 7| 2| 5| 7| 3| 4| 7| 7| 3| 6| 7| 7| 3| 7| 6| 4| 7| 4| 4| 7| 4|             
                             DAY ON TEST   | 3| 1| 3| 4| 3| 1| 7| 3| 0| 5| 2| 3| 2| 7| 2| 2| 8| 3| 0| 5| 3| 5| 3| 3| 5|             
                                           | 1| 8| 1| 7| 0| 3| 3| 1| 3| 7| 9| 0| 3| 8| 9| 9| 6| 1| 1| 7| 1| 7| 4| 0| 7|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    150 MG/K                               | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
      Hyperplasia, Chronic, Cystic         |                                              3                           |             
      Inflammation, Suppurative            |                                                                          |             
      Artery, Mineralization, Focal        |                                                                          |             
      Cervix, Fibrosis                     |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +  +  +  +  +  +     +  +  M  +  +  +  +  +  +     +     +  +   |             
      Erythroid Cell, Proliferation        |                                           4                              |             
      Myeloid Cell, Proliferation          |                                                       3                  |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
      Congestion                           |                                                                          |             
      Axillary, Hyperplasia, Plasma Cell   |                                                       4                  |             
      Mandibular, Congestion               |                                                                          |             
      Mandibular, Hyperplasia, Plasma Cell |       4                                                                  |             
      Mediastinal, Congestion              |                                                                          |             
      Mediastinal, Hemorrhage              |                                                       3                  |             
      Mediastinal, Hyperplasia, Plasma Cell|                                                       3                  |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
      Granuloma, Focal                     |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
      Congestion, Focal                    |                                                       2                  |             
      Hematocyst                           |                                                                          |             
      Hematopoietic Cell Proliferation     |    2                                      3                              |             
      Hematopoietic Cell Proliferation     |                                                                          |             
          Granulocytic                     |                                                       4                  |             
      Necrosis, Acute, Focal               |                                                                          |             
      Capsule, Fibrosis                    |                                                                          |             
                                            __________________________________________________________________________|             
   Thymus                                  | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
      Cyst                                 |                                                    X                     |             
      Hemorrhage                           |    2           2                    3                                    |             
      Epithelial Cell, Hyperplasia         |                                                             4            |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
                                            __________________________________________________________________________|             
   Skin                                    | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +  +  +  +  +  +  +  +  +     +  +  M  +  +  +  +  +  +     +     +  +   |             
      Femur, Fibrous Osteodystrophy        |                                                                          |             
      Femur, Osteopetrosis                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
      Hemorrhage, Focal                    |                         2                                                |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  47                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 7| 4| 7| 2| 5| 7| 3| 4| 7| 7| 3| 6| 7| 7| 3| 7| 6| 4| 7| 4| 4| 7| 4|             
                             DAY ON TEST   | 3| 1| 3| 4| 3| 1| 7| 3| 0| 5| 2| 3| 2| 7| 2| 2| 8| 3| 0| 5| 3| 5| 3| 3| 5|             
                                           | 1| 8| 1| 7| 0| 3| 3| 1| 3| 7| 9| 0| 3| 8| 9| 9| 6| 1| 1| 7| 1| 7| 4| 0| 7|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    150 MG/K                               | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Spinal Cord                             |                         +                                                |             
      Hemorrhage, Focal                    |                         4                                                |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Larynx                                  |       +                                                                  |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
      Congestion                           |    3           2                    3                             3      |             
      Emphysema, Focal                     |                                                                          |             
      Hemorrhage, Focal                    |                         2                                                |             
      Hyperplasia, Focal                   | 1                                            1                           |             
      Inflammation, Acute, Focal           |                                                                          |             
      Inflammation, Chronic, Focal         |                                              1                           |             
      Interstitium, Mineralization, Focal  |                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
      Foreign Body                         | 2     2                                                                  |             
      Fungus                               |                      X                          X                        |             
      Inflammation, Chronic, Focal         |                      3                                                   |             
      Inflammation, Focal, Suppurative     | 1     2                       2                 2                        |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
      Mineralization, Focal                |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |                                                                      +   |             
      Lens, Cataract                       |                                                                      2   |             
      Retina, Degeneration                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
      Congestion                           |                                                                          |             
      Cyst                                 |                                                                          |             
      Hydronephrosis                       |                   4                                                      |             
      Mineralization                       |                1                                                         |             
      Nephropathy, Chronic                 |    3  2  2  3        4        4  2  1  2  1  2     2  1     4     1  2   |             
      Pigmentation                         |          2                                                               |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +     +  +   |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  48                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 3| 6| 7| 6| 4| 7| 4| 6| 7| 4| 2| 7| 7| 4| 2| 7| 6| 6| 6| 3| 7| 7| 6| 7| 7|             
                             DAY ON TEST   | 8| 9| 3| 9| 5| 3| 4| 2| 2| 5| 1| 0| 3| 5| 9| 3| 3| 5| 8| 1| 2| 3| 9| 2| 3|             
                                           | 5| 0| 0| 5| 7| 1| 4| 1| 9| 7| 8| 2| 1| 7| 0| 0| 1| 8| 9| 0| 9| 1| 4| 9| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    150 MG/K                               | 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|             
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +  +  +     +  +  +  +     +  +  +     +  +  M  +  +  +  M  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +     +  +     +  +  A  +     +  A  +     +  +  +  A  +  +  +  +  +  +  +|             
      Parasite Metazoan                    |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +     +  +     +  +  A  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
      Parasite Metazoan                    | X                       X                          X                     |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +     +  +     +  +  A  +     +  +  +     +  +  +  M  +  +  +  +  +  +  +|             
      Parasite Metazoan                    |                                     X                                    |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  +     +  +  A  +     +  +  +     +  +  +  A  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +     +  +  A  +     +  A  +     +  +  +  A  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +     +  +  A  +     +  +  +     +  +  +  A  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
      Angiectasis, Focal                   |                                                                          |             
      Basophilic Focus                     |                                                    X                    X|             
      Basophilic Focus, Multiple           |    X  X        X        X        X  X        X        X     X  X  X  X   |             
      Clear Cell Focus                     | X                 X                                                      |             
      Clear Cell Focus, Multiple           |                                              X                           |             
      Cytoplasmic Alteration, Focal        |    3                                                                     |             
      Granuloma, Focal                     |                4                                                         |             
      Hematopoietic Cell Proliferation     |                                                       1                  |             
      Hepatodiaphragmatic Nodule           |    X                 X           X  X                                X   |             
      Inflammation, Chronic, Focal         |    1  1        4  2     3           2                 2     3  1     2  2|             
      Necrosis, Focal                      |          1                       1                                       |             
      Bile Duct, Cyst                      |                                                                          |             
      Bile Duct, Hyperplasia               |    2  2  4     1     3  1        3  3        2     2        2  2  2  2  1|             
      Centrilobular, Fatty Change          |                                                 2                        |             
                                            __________________________________________________________________________|             
   Mesentery                               |    +     +                                                        +      |             
      Fat, Necrosis                        |    2     3                                                               |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +  +     +  +  A  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
      Atrophy, Focal                       |    1                             1        1     2  1        2        2   |             
      Hyperplasia, Focal                   |                                                                          |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
      Cyst                                 |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
      Inflammation, Acute, Diffuse         |                   3                                                      |             
      Mineralization                       | 3                                                                        |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
      Erosion                              |                                                                   1      |             
      Inflammation, Acute, Focal           |                                                                          |             
      Mineralization                       | 3                                                                        |             
                                            __________________________________________________________________________|             
   Tooth                                   |                                                                          |             
      Inflammation, Chronic                |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  49                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 3| 6| 7| 6| 4| 7| 4| 6| 7| 4| 2| 7| 7| 4| 2| 7| 6| 6| 6| 3| 7| 7| 6| 7| 7|             
                             DAY ON TEST   | 8| 9| 3| 9| 5| 3| 4| 2| 2| 5| 1| 0| 3| 5| 9| 3| 3| 5| 8| 1| 2| 3| 9| 2| 3|             
                                           | 5| 0| 0| 5| 7| 1| 4| 1| 9| 7| 8| 2| 1| 7| 0| 0| 1| 8| 9| 0| 9| 1| 4| 9| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    150 MG/K                               | 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|             
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
      Inflammation, Chronic, Focal         | 3     2        2        2        2           2  2              2     2  2|             
      Mineralization, Multifocal           | 3                                                                        |             
      Artery, Hyperplasia, Focal           |                         3                                                |             
      Artery, Mineralization               |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
      Degeneration, Diffuse, Fatty         |                                                                   4      |             
      Degeneration, Fatty, Focal           |                                              1        2        2     3   |             
      Hyperplasia, Focal                   |       2        3        2                                            1   |             
      Hypertrophy, Focal                   |                                                                1         |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +  +     +  M  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
      Angiectasis                          |                                                                          |             
      Hyperplasia                          |          2           2  1        1                    1                  |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +     +  +  A  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
      Hyperplasia, Focal                   |                                                             2            |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +  M  +  +     +  +  +  +     +  +  +     M  +  M  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
      Angiectasis                          |       3              2  2                       3                        |             
      Cyst                                 |       X                 X                 X  X  X  X     X  X            |             
      Cyst, Multiple                       |                X                                                         |             
      Pars Distalis, Angiectasis           |                                                                          |             
      Pars Distalis, Hyperplasia, Focal    |       3                                            3                     |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +     +  +  +  +     +  +  +     +  +  M  +  +  +  +  +  +  +  +|             
      C-Cell, Hyperplasia, Focal           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Clitoral Gland                          | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  M  +  +|             
      Atrophy                              |                                                                          |             
      Dilatation                           |                                     3        4                           |             
      Hyperplasia, Focal                   |                                                                3         |             
      Inflammation, Chronic, Focal         |                                                                         3|             
                                            __________________________________________________________________________|             
   Ovary                                   | +  +  +  +     +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
      Cyst                                 |    X                                         X                           |             
                                            __________________________________________________________________________|             
   Uterus                                  | +  +  +  +  +  +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
      Dilatation                           |                               3                                          |             
      Hydrometra                           |                                                          2               |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  50                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 3| 6| 7| 6| 4| 7| 4| 6| 7| 4| 2| 7| 7| 4| 2| 7| 6| 6| 6| 3| 7| 7| 6| 7| 7|             
                             DAY ON TEST   | 8| 9| 3| 9| 5| 3| 4| 2| 2| 5| 1| 0| 3| 5| 9| 3| 3| 5| 8| 1| 2| 3| 9| 2| 3|             
                                           | 5| 0| 0| 5| 7| 1| 4| 1| 9| 7| 8| 2| 1| 7| 0| 0| 1| 8| 9| 0| 9| 1| 4| 9| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    150 MG/K                               | 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|             
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
      Hyperplasia, Chronic, Cystic         |                                                                          |             
      Inflammation, Suppurative            |                4                                                         |             
      Artery, Mineralization, Focal        |                                              2                           |             
      Cervix, Fibrosis                     |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +     +  +  A  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
      Erythroid Cell, Proliferation        |                                                                          |             
      Myeloid Cell, Proliferation          |                                                                   3      |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
      Congestion                           |                                  2                                       |             
      Axillary, Hyperplasia, Plasma Cell   |                                                                          |             
      Mandibular, Congestion               |    3                                                                     |             
      Mandibular, Hyperplasia, Plasma Cell |    2                                                                     |             
      Mediastinal, Congestion              |    2                                                                     |             
      Mediastinal, Hemorrhage              |                                                                          |             
      Mediastinal, Hyperplasia, Plasma Cell|                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
      Granuloma, Focal                     |                1                                                         |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
      Congestion, Focal                    |                                                                          |             
      Hematocyst                           |                      X                                                   |             
      Hematopoietic Cell Proliferation     | 3                    4                                2                  |             
      Hematopoietic Cell Proliferation     |                                                                          |             
          Granulocytic                     |                                                                          |             
      Necrosis, Acute, Focal               |                                                 3                        |             
      Capsule, Fibrosis                    |                                  1                                       |             
                                            __________________________________________________________________________|             
   Thymus                                  | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  M  M|             
      Cyst                                 |                                                                          |             
      Hemorrhage                           |                               1                          2               |             
      Epithelial Cell, Hyperplasia         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Skin                                    | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
      Femur, Fibrous Osteodystrophy        | X                                                                        |             
      Femur, Osteopetrosis                 |                                                                4         |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  M  +  +|             
      Hemorrhage, Focal                    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  51                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 _____________________________________________________________________________________________________________________              
                                           | 3| 6| 7| 6| 4| 7| 4| 6| 7| 4| 2| 7| 7| 4| 2| 7| 6| 6| 6| 3| 7| 7| 6| 7| 7|             
                             DAY ON TEST   | 8| 9| 3| 9| 5| 3| 4| 2| 2| 5| 1| 0| 3| 5| 9| 3| 3| 5| 8| 1| 2| 3| 9| 2| 3|             
                                           | 5| 0| 0| 5| 7| 1| 4| 1| 9| 7| 8| 2| 1| 7| 0| 0| 1| 8| 9| 0| 9| 1| 4| 9| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    150 MG/K                               | 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|             
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Spinal Cord                             |                                                                          |             
      Hemorrhage, Focal                    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Larynx                                  |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
      Congestion                           |    4  2                       2                                   3      |             
      Emphysema, Focal                     |                                                    2                     |             
      Hemorrhage, Focal                    |                                  1                                       |             
      Hyperplasia, Focal                   |                                                                          |             
      Inflammation, Acute, Focal           |                                                 2                        |             
      Inflammation, Chronic, Focal         |       2                 3     2                    1                     |             
      Interstitium, Mineralization, Focal  | 4                                                                        |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
      Foreign Body                         |                                  1                                       |             
      Fungus                               |                                                                          |             
      Inflammation, Chronic, Focal         |                                                                          |             
      Inflammation, Focal, Suppurative     |                                  1                                       |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
      Mineralization, Focal                | 3                                                                        |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |                         +                                         +      |             
      Lens, Cataract                       |                         2                                                |             
      Retina, Degeneration                 |                         4                                                |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +  +     +  +  +  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
      Congestion                           |                                  3                                       |             
      Cyst                                 |                X                                                         |             
      Hydronephrosis                       |                                                                          |             
      Mineralization                       | 3                                                                        |             
      Nephropathy, Chronic                 | 4  3  3  1     2  2  1  3        2  3     2  1  1  1  3     2  3  1  3  3|             
      Pigmentation                         |                                                    3                     |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +     +  +  A  +     +  +  +     +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page  52                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 __________________________________________________________________________________________________________________________________ 
                                           | 4| 4| 6| 7| 7| 4| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 5| 5| 2| 1| 0| 5| 2| 2| 3| 3|                                            |            |
                                           | 7| 7| 4| 6| 2| 7| 9| 9| 0| 0|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|                                            |      A     |
    150 MG/K                               | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|                                            |      L     |
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               |       +  +  +     +  +  +  +                                             |  48        |
                                            __________________________________________________________________________|____________|
   Intestine Large                         |       +  +  +     +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  |       +  +  +     +  +  +  +                                             |  46        |
      Parasite Metazoan                    |                                                                          |      1     |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  |       +  +  +     +  +  +  +                                             |  48        |
      Parasite Metazoan                    |                                                                          |      6     |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 |       +  +  +     +  +  +  +                                             |  47        |
      Parasite Metazoan                    |                                                                          |      4     |
                                            __________________________________________________________________________|____________|
   Intestine Small                         |       +  +  +     +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               |       +  +  +     +  +  +  +                                             |  48        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  |       +  +  +     +  +  +  +                                             |  47        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                |       +  +  +     +  +  +  +                                             |  48        |
                                            __________________________________________________________________________|____________|
   Liver                                   |       +  +  +  +  +  +  +  +                                             |  51        |
      Angiectasis, Focal                   |                                                                          |      1  2.0|
      Basophilic Focus                     |          X                                                               |      7     |
      Basophilic Focus, Multiple           |             X     X  X  X  X                                             |     27     |
      Clear Cell Focus                     |                                                                          |      7     |
      Clear Cell Focus, Multiple           |                                                                          |      1     |
      Cytoplasmic Alteration, Focal        |                                                                          |      1  3.0|
      Granuloma, Focal                     |                                                                          |      1  4.0|
      Hematopoietic Cell Proliferation     |                                                                          |      2  1.5|
      Hepatodiaphragmatic Nodule           |                                                                          |      7     |
      Inflammation, Chronic, Focal         |                   2  2  2  2                                             |     24  2.2|
      Necrosis, Focal                      |                                                                          |      2  1.0|
      Bile Duct, Cyst                      |                                                                          |      1     |
      Bile Duct, Hyperplasia               |       4     4     1  2  3  2                                             |     35  2.1|
      Centrilobular, Fatty Change          |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Mesentery                               |                                                                          |   3        |
      Fat, Necrosis                        |                                                                          |      2  2.5|
                                            __________________________________________________________________________|____________|
   Pancreas                                |       +  +  +     +  +  +  +                                             |  49        |
      Atrophy, Focal                       |                      1                                                   |     13  1.5|
      Hyperplasia, Focal                   |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Salivary Glands                         |       +  +  +     +  +  +  +                                             |  50        |
      Cyst                                 |                                                                          |      1     |
                                            __________________________________________________________________________|____________|
   Stomach                                 |       +  +  +     +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    |       +  +  +     +  +  +  +                                             |  50        |
      Inflammation, Acute, Diffuse         |                                                                          |      1  3.0|
      Mineralization                       |                                                                          |      2  2.5|
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      |       +  +  +     +  +  +  +                                             |  50        |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  53                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 __________________________________________________________________________________________________________________________________ 
                                           | 4| 4| 6| 7| 7| 4| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 5| 5| 2| 1| 0| 5| 2| 2| 3| 3|                                            |            |
                                           | 7| 7| 4| 6| 2| 7| 9| 9| 0| 0|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|                                            |      A     |
    150 MG/K                               | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|                                            |      L     |
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM - cont                  |                                                                          |            |
                                           |                                                                          |            |
      Erosion                              |                                                                          |      1  1.0|
      Inflammation, Acute, Focal           |                                                                          |      1  2.0|
      Mineralization                       |                                                                          |      2  2.5|
                                            __________________________________________________________________________|____________|
   Tooth                                   |                                                                          |   1        |
      Inflammation, Chronic                |                                                                          |      1  3.0|
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Heart                                   |       +  +  +     +  +  +  +                                             |  50        |
      Inflammation, Chronic, Focal         |       1           2  3  1                                                |     22  2.0|
      Mineralization, Multifocal           |                                                                          |      1  3.0|
      Artery, Hyperplasia, Focal           |                                                                          |      1  3.0|
      Artery, Mineralization               |                                                                          |      1  3.0|
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           |       +  +  +     +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   |       +  +  +     +  +  +  +                                             |  50        |
      Degeneration, Diffuse, Fatty         |                                                                          |      1  4.0|
      Degeneration, Fatty, Focal           |       2  1           2                                                   |     10  2.1|
      Hyperplasia, Focal                   |                      2                                                   |      7  2.0|
      Hypertrophy, Focal                   |                                                                          |      2  1.0|
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  |       +  +  +     +  +  M  +                                             |  48        |
      Angiectasis                          |                                                                          |      1  3.0|
      Hyperplasia                          |                                                                          |      8  1.9|
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      |       +  +  +     +  +  +  +                                             |  49        |
      Hyperplasia, Focal                   |             3                                                            |      2  2.5|
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       |       +  +  +     +  +  +  +                                             |  41        |
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         |       +  +  +     +  +  +  +                                             |  52        |
      Angiectasis                          |                      3                                                   |      7  2.7|
      Cyst                                 |          X  X     X  X                                                   |     19     |
      Cyst, Multiple                       |                                                                          |      2     |
      Pars Distalis, Angiectasis           |                                                                          |      1  3.0|
      Pars Distalis, Hyperplasia, Focal    |          2              2                                                |      5  2.4|
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           |       +  +  +     +  +  +  +                                             |  50        |
      C-Cell, Hyperplasia, Focal           |                                                                          |      1  1.0|
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  54                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 __________________________________________________________________________________________________________________________________ 
                                           | 4| 4| 6| 7| 7| 4| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 5| 5| 2| 1| 0| 5| 2| 2| 3| 3|                                            |            |
                                           | 7| 7| 4| 6| 2| 7| 9| 9| 0| 0|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|                                            |      A     |
    150 MG/K                               | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|                                            |      L     |
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 GENITAL SYSTEM - cont                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Clitoral Gland                          |       +  +  +     +  +  +  +                                             |  49        |
      Atrophy                              |                                                                          |      1  4.0|
      Dilatation                           |                                                                          |      3  3.7|
      Hyperplasia, Focal                   |                            2                                             |      3  2.3|
      Inflammation, Chronic, Focal         |             2                                                            |      2  2.5|
                                            __________________________________________________________________________|____________|
   Ovary                                   |       +  +  +     +  +  +  +                                             |  51        |
      Cyst                                 |                                                                          |      2     |
                                            __________________________________________________________________________|____________|
   Uterus                                  |       +  +  +     +  +  +  +                                             |  52        |
      Dilatation                           |                                                                          |      1  3.0|
      Hydrometra                           |                                                                          |      1  2.0|
      Hyperplasia, Chronic, Cystic         |                            2                                             |      2  2.5|
      Inflammation, Suppurative            |                                                                          |      1  4.0|
      Artery, Mineralization, Focal        |                                                                          |      1  2.0|
      Cervix, Fibrosis                     |                         4                                                |      1  4.0|
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             |       +  +  +     +  +  +  +                                             |  48        |
      Erythroid Cell, Proliferation        |                                                                          |      1  4.0|
      Myeloid Cell, Proliferation          |                                                                          |      2  3.0|
                                            __________________________________________________________________________|____________|
   Lymph Node                              |       +  +  +     +  +  +  +                                             |  50        |
      Congestion                           |                                                                          |      1  2.0|
      Axillary, Hyperplasia, Plasma Cell   |                                                                          |      1  4.0|
      Mandibular, Congestion               |                                                                          |      1  3.0|
      Mandibular, Hyperplasia, Plasma Cell |                                                                          |      2  3.0|
      Mediastinal, Congestion              |                                                                          |      1  2.0|
      Mediastinal, Hemorrhage              |          2                                                               |      2  2.5|
      Mediastinal, Hyperplasia, Plasma Cell|                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  |       +  +  +     +  +  +  +                                             |  50        |
      Granuloma, Focal                     |                                                                          |      1  1.0|
                                            __________________________________________________________________________|____________|
   Spleen                                  |       +  +  +     +  +  +  +                                             |  50        |
      Congestion, Focal                    |                   2                                                      |      2  2.0|
      Hematocyst                           |                                                                          |      1     |
      Hematopoietic Cell Proliferation     |                                                                          |      5  2.8|
      Hematopoietic Cell Proliferation     |                                                                          |            |
          Granulocytic                     |                                                                          |      1  4.0|
      Necrosis, Acute, Focal               |                                                                          |      1  3.0|
      Capsule, Fibrosis                    |                                                                          |      1  1.0|
                                            __________________________________________________________________________|____________|
   Thymus                                  |       +  +  +     +  +  +  +                                             |  48        |
      Cyst                                 |          X                                                               |      2     |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  55                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 __________________________________________________________________________________________________________________________________ 
                                           | 4| 4| 6| 7| 7| 4| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 5| 5| 2| 1| 0| 5| 2| 2| 3| 3|                                            |            |
                                           | 7| 7| 4| 6| 2| 7| 9| 9| 0| 0|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|                                            |      A     |
    150 MG/K                               | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|                                            |      L     |
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
      Hemorrhage                           |                                                                          |      5  2.0|
      Epithelial Cell, Hyperplasia         |                                                                          |      1  4.0|
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           |       +  +  +     +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Skin                                    |       +  +  +     +  +  +  +                                             |  50        |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    |       +  +  +     +  +  +  +                                             |  49        |
      Femur, Fibrous Osteodystrophy        |                                                                          |      1     |
      Femur, Osteopetrosis                 |                      4                                                   |      2  4.0|
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   |       +  +  +     +  +  +  +                                             |  49        |
      Hemorrhage, Focal                    |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Spinal Cord                             |                                                                          |   1        |
      Hemorrhage, Focal                    |                                                                          |      1  4.0|
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Larynx                                  |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Lung                                    |       +  +  +     +  +  +  +                                             |  50        |
      Congestion                           |                                                                          |      8  2.8|
      Emphysema, Focal                     |                                                                          |      1  2.0|
      Hemorrhage, Focal                    |                                                                          |      2  1.5|
      Hyperplasia, Focal                   |                                                                          |      2  1.0|
      Inflammation, Acute, Focal           |                                                                          |      1  2.0|
      Inflammation, Chronic, Focal         |                                                                          |      5  1.8|
      Interstitium, Mineralization, Focal  |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Nose                                    |       +  +  +     +  +  +  +                                             |  50        |
      Foreign Body                         |       2                                                                  |      4  1.8|
      Fungus                               |       X                                                                  |      3     |
      Inflammation, Chronic, Focal         |                                                                          |      1  3.0|
      Inflammation, Focal, Suppurative     |       2                                                                  |      6  1.7|
                                            __________________________________________________________________________|____________|
   Trachea                                 |       +  +  +     +  +  +  +                                             |  50        |
      Mineralization, Focal                |                                                                          |      1  3.0|
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Eye                                     |                                                                          |   3        |
      Lens, Cataract                       |                                                                          |      2  2.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  56                                                               
NTP Experiment-Test: 05704-03                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 07:49:44  
 __________________________________________________________________________________________________________________________________ 
                                           | 4| 4| 6| 7| 7| 4| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 5| 5| 2| 1| 0| 5| 2| 2| 3| 3|                                            |            |
                                           | 7| 7| 4| 6| 2| 7| 9| 9| 0| 0|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|                                            |      A     |
    150 MG/K                               | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|                                            |      L     |
    G                                      | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 SPECIAL SENSES SYSTEM - cont              |                                                                          |            |
                                           |                                                                          |            |
      Retina, Degeneration                 |                                                                          |      1  4.0|
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  |       +  +  +     +  +  +  +                                             |  50        |
      Congestion                           |          2  2                                                            |      3  2.3|
      Cyst                                 |                                                                          |      1     |
      Hydronephrosis                       |                                                                          |      1  4.0|
      Mineralization                       |                                                                          |      2  2.0|
      Nephropathy, Chronic                 |       2  2  1     2  3  3  2                                             |     43  2.2|
      Pigmentation                         |       4                                                                  |      3  3.0|
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         |       +  +  +     +  +  +  +                                             |  49        |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  57                                                               
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