TDMS Study 56111-03 Pathology Tables
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: Battelle Columbus TRANS-CINNAMALDEHYDE DATE: 06/01/01
EXPERIMENT: 56111 TEST: 03 TIME: 11:32:20
CAGES FROM 0000 TO LAST CAGE PAGE: 1
TEST TYPE: CHRONIC ROUTE: DOSED FEED NTP: C56111B
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REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: BATTELLE COLUMBUS LABORATORY TRANS-CINNAMALDEHYDE DATE: 06/01/01
EXPERIMENT: 56111 TEST: 03 TIME: 11:41:36
SPECIES: RATS, FISCHER 344
TEST TYPE: TWO YEAR ROUTE: DOSED FEED NTP: 56111B
CONT: N01-ES-55384 CAS: 14371-10-9
MEAN BODY WEIGHTS AND SURVIVAL OF MALE RATS IN THE
TWO YEAR DOSED FEED STUDY OF TRANS-CINNAMALDEHYDE
===================================================================================================================================
WEEK UNTREATDCONTROL VEHICLE CONTROL .312% .625% 1.25%
---------------- ---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
==================================================================================================================================
B 97.7 50 97.3 99.6 50 97.8 100.1 50 97.6 99.9 50 97.9 100.2 50
1 97.7 50 97.3 99.6 50 97.8 100.1 50 97.6 99.9 50 97.9 100.2 50
2 133.8 50 134.1 100.2 50 132.2 98.8 50 128.9 96.3 50 121.6 90.9 50
6 252.7 50 255.0 100.9 50 251.7 99.6 50 244.1 96.6 50 236.6 93.6 50
10 306.7 50 307.9 100.4 50 303.8 99.1 50 293.9 95.8 50 283.7 92.5 50
14 343.3 50 349.9 101.9 50 341.8 99.6 50 329.0 95.8 50 320.1 93.2 50
18 374.2 50 377.6 100.9 50 368.1 98.4 50 358.0 95.7 50 345.2 92.3 50
22 393.1 50 396.7 100.9 50 381.7 97.1 50 375.1 95.4 49 360.5 91.7 50
26 403.5 50 409.9 101.6 50 396.5 98.3 49 387.4 96.0 49 372.8 92.4 50
30 420.5 50 423.9 100.8 50 413.2 98.3 49 403.9 96.1 48 388.4 92.4 50
34 439.2 50 443.8 101.0 50 430.0 97.9 49 419.6 95.5 48 403.6 91.9 50
38 444.5 50 448.1 100.8 50 438.0 98.5 49 428.5 96.4 48 410.6 92.4 50
42 458.4 50 463.1 101.0 50 449.4 98.0 49 439.7 95.9 48 420.5 91.7 50
46 465.6 50 468.4 100.6 50 455.9 97.9 49 446.4 95.9 48 426.7 91.6 50
50 467.5 50 474.8 101.6 50 461.6 98.7 49 452.5 96.8 48 433.2 92.7 50
54 473.8 50 484.0 102.2 50 467.8 98.7 49 458.2 96.7 48 437.9 92.4 50
58 477.9 50 481.5 100.8 50 468.3 98.0 49 463.3 96.9 48 441.2 92.3 50
62 472.2 50 476.1 100.8 50 465.5 98.6 48 457.4 96.9 48 438.2 92.8 50
66 479.2 50 488.7 102.0 49 471.3 98.4 48 461.3 96.3 48 444.8 92.8 50
70 478.1 50 480.2 100.4 49 471.8 98.7 48 463.7 97.0 48 442.2 92.5 50
74 482.7 49 485.0 100.5 46 475.2 98.4 48 468.0 97.0 46 444.6 92.1 49
78 482.4 48 486.3 100.8 46 476.3 98.7 48 468.7 97.2 44 444.3 92.1 49
82 485.1 48 490.9 101.2 45 475.6 98.0 48 469.5 96.8 43 448.2 92.4 49
86 478.0 46 486.8 101.8 42 474.4 99.2 46 466.6 97.6 40 445.0 93.1 49
90 480.0 43 492.1 102.5 37 474.6 98.9 45 460.2 95.9 35 440.4 91.8 49
94 476.7 42 484.6 101.7 35 475.4 99.7 43 461.4 96.8 33 443.5 93.0 48
98 479.8 39 488.3 101.8 33 465.6 97.0 42 451.2 94.0 30 439.2 91.5 45
102 469.8 36 486.9 103.6 32 467.3 99.5 38 443.0 94.3 28 434.8 92.6 43
TERM. SAC. 29 31 36 27 41
===================================================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.
MEAN BODY WEIGHTS AND SURVIVAL OF FEMALE RATS IN THE
TWO YEAR DOSED FEED STUDY OF TRANS-CINNAMALDEHYDE
===================================================================================================================================
WEEK UNTREATDCONTROL VEHICLE CONTROL .312% .625% 1.25%
---------------- ---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
==================================================================================================================================
B 92.4 50 94.2 101.9 50 91.2 98.7 50 92.8 100.4 50 93.9 101.6 50
1 92.4 50 94.2 101.9 50 91.2 98.7 50 92.8 100.4 50 93.9 101.6 50
2 113.3 50 113.4 100.1 50 113.1 99.8 50 112.5 99.3 50 110.0 97.1 50
6 162.0 50 163.1 100.7 50 159.5 98.5 50 159.7 98.6 50 155.9 96.2 50
10 180.8 50 181.5 100.4 50 178.6 98.8 50 175.2 96.9 49 173.4 95.9 50
14 191.4 50 191.1 99.8 50 193.6 101.1 49 187.1 97.8 49 184.8 96.6 50
18 200.5 50 200.5 100.0 50 200.6 100.0 49 198.1 98.8 49 190.6 95.1 50
22 208.5 50 212.3 101.8 50 211.5 101.4 49 204.3 98.0 49 199.5 95.7 50
26 210.6 50 214.0 101.6 50 213.9 101.6 49 207.1 98.3 49 201.0 95.4 49
30 220.2 49 220.6 100.2 50 221.5 100.6 49 215.0 97.6 48 207.1 94.1 49
34 230.1 49 233.5 101.5 50 231.7 100.7 49 224.7 97.7 48 217.6 94.6 49
38 236.3 49 237.6 100.6 50 238.6 101.0 49 229.2 97.0 48 221.5 93.7 49
42 242.6 49 246.8 101.7 50 246.4 101.6 49 239.3 98.6 48 227.7 93.9 49
46 250.4 49 255.4 102.0 50 254.6 101.7 49 245.6 98.1 48 236.4 94.4 49
50 261.1 49 262.2 100.4 50 264.3 101.2 49 253.1 96.9 48 242.6 92.9 49
54 271.0 49 274.1 101.1 50 273.7 101.0 49 263.7 97.3 48 252.1 93.0 49
58 278.2 49 282.9 101.7 50 279.6 100.5 49 269.3 96.8 48 258.3 92.8 49
62 286.0 49 288.8 101.0 50 288.0 100.7 49 276.3 96.6 48 265.8 92.9 49
66 291.7 49 294.0 100.8 50 293.4 100.6 49 282.5 96.8 48 270.8 92.8 49
70 296.7 49 299.1 100.8 50 298.6 100.6 49 288.3 97.2 46 277.2 93.4 49
74 308.4 49 309.9 100.5 50 309.6 100.4 49 298.2 96.7 45 285.7 92.6 49
78 309.2 49 315.7 102.1 48 311.7 100.8 49 298.2 96.4 45 285.6 92.4 48
82 314.7 48 319.7 101.6 48 317.6 100.9 48 307.5 97.7 44 290.6 92.3 47
86 321.4 47 324.3 100.9 48 321.3 100.0 48 313.4 97.5 44 295.4 91.9 45
90 327.6 45 330.6 100.9 46 325.3 99.3 45 315.1 96.2 42 300.6 91.8 44
94 325.1 44 336.4 103.5 45 326.8 100.5 44 325.7 100.2 41 309.7 95.3 41
98 330.8 40 338.1 102.2 42 328.7 99.4 39 329.5 99.6 39 309.6 93.6 39
102 328.6 37 344.4 104.8 37 332.2 101.1 35 337.3 102.6 37 309.3 94.1 36
TERM. SAC. 34 36 33 35 33
===================================================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.