TDMS Study 56111-04 Pathology Tables
NTP FEED, WATER, AND COMPOUND CONSUMPTION TABLE REPORT: EISRPT39
LAB: Battelle Columbus TRANS-CINNAMALDEHYDE DATE: 06/14/01
EXPERIMENT: 56111 TEST: 04 TIME: 08:33:59
CAGES FROM 0000 TO LAST CAGE PAGE: 1
TEST TYPE: CHRONIC ROUTE: DOSED FEED NTP: C56111B
------------------------------------------------------------------------------------------------------------------------------------
REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP FEED, WATER, AND COMPOUND CONSUMPTION TABLE REPORT: EISRPT39
LAB: BATTELLE COLUMBUS LABORATORY TRANS-CINNAMALDEHYDE DATE: 06/14/01
EXPERIMENT: 56111 TEST: 04 TIME: 8:55:36
TEST TYPE: CHRONIC ROUTE: DOSED FEED NTP: 56111B
CONT: N01-ES-55384 CAS: 14371-10-9
FEED AND COMPOUND CONSUMPTION BY MALE MICE IN THE
CHRONIC DOSED FEED STUDY OF TRANS-CINNAMALDEHYDE
==================================================================================================================================
UNTREATDCONTROL VEHICLE CONTROL .312% .625%
---------------- --------------------------------- --------------------------------- ---------------------------------
DOSE/ DOSE/ DOSE/
GRAMS BODY GRAMS BODY CONTROL GRAMS BODY CONTROL GRAMS BODY CONTROL
FEED/ WEIGHT FEED/ WEIGHT FEED (B) DOSE/ FEED/ WEIGHT FEED (B) DOSE/ FEED/ WEIGHT FEED (B) DOSE/
WEEK DAY(A) (GRAMS) DAY(A) (GRAMS) (GRAMS) DAY(C) DAY(A) (GRAMS) (GRAMS) DAY(C) DAY(A) (GRAMS) (GRAMS) DAY(C)
==================================================================================================================================
2 4.5 22.2 4.4 22.8 0.98 0 4.4 22.4 0.98 614 4.3 22.0 0.96 1227
6 4.5 25.6 4.5 25.8 1.00 0 4.4 25.9 0.98 530 4.5 25.3 1.00 1121
9 4.7 29.3 4.8 29.9 1.02 0 4.6 29.2 0.98 493 4.8 28.3 1.02 1058
13 4.3 31.8 4.5 32.3 1.05 0 4.4 31.5 1.02 433 4.4 30.3 1.02 904
18 4.5 34.8 4.5 35.4 1.00 0 4.3 34.5 0.96 390 4.7 32.4 1.04 909
22 4.5 36.8 4.6 36.9 1.02 0 4.5 36.7 1.00 384 4.7 34.4 1.04 848
26 4.5 38.9 4.5 39.1 1.00 0 4.5 39.0 1.00 359 4.4 36.4 0.98 758
30 4.2 40.2 4.3 40.6 1.02 0 4.1 40.5 0.98 319 4.2 38.2 1.00 693
34 4.5 42.0 4.5 42.5 1.00 0 4.4 42.4 0.98 321 4.4 39.9 0.98 684
38 4.8 42.2 4.9 42.6 1.02 0 4.8 42.2 1.00 353 4.7 40.1 0.98 741
42 4.5 42.2 4.6 43.0 1.02 0 4.5 42.6 1.00 327 4.3 40.0 0.96 679
46 4.8 43.0 4.9 43.7 1.02 0 4.8 43.2 1.00 348 4.8 40.7 1.00 739
50 4.5 44.2 4.7 45.4 1.04 0 4.5 44.6 1.00 311 4.6 42.4 1.02 684
54 4.6 45.3 4.7 46.0 1.02 0 4.6 45.3 1.00 315 4.6 43.1 1.00 660
58 4.6 45.5 4.6 46.5 1.00 0 4.5 45.9 0.98 306 4.6 43.2 1.00 660
62 4.5 44.5 4.7 46.1 1.04 0 4.4 45.1 0.98 302 4.5 42.1 1.00 664
66 4.6 43.6 4.7 45.1 1.02 0 4.6 44.0 1.00 323 4.6 41.1 1.00 696
70 4.7 43.5 4.8 44.8 1.02 0 4.7 43.8 1.00 335 4.6 40.5 0.98 714
74 4.7 43.1 4.7 43.8 1.00 0 4.4 42.4 0.94 322 4.4 39.0 0.94 701
78 4.3 39.6 4.6 40.5 1.07 0 4.0 38.3 0.93 330 4.3 35.0 1.00 759
82 4.8 38.3 4.9 38.9 1.02 0 4.7 36.8 0.98 400 4.9 33.6 1.02 910
86 4.9 37.4 4.9 37.9 1.00 0 4.8 35.6 0.98 417 4.9 32.6 1.00 933
90 4.9 34.7 4.8 35.4 0.98 0 4.9 33.4 1.00 455 5.1 32.1 1.04 993
94 4.2 34.6 4.5 35.9 1.07 0 4.3 33.7 1.02 396 4.3 32.6 1.02 833
98 4.5 34.6 4.6 36.0 1.02 0 4.4 33.2 0.98 412 4.3 32.2 0.96 840
102 4.5 34.8 4.6 35.6 1.02 0 4.3 33.1 0.96 406 4.5 32.3 1.00 870
1 TO 13 WEEKS
----------------
MEAN 4.5 27.2 4.5 27.7 1.01 0 4.4 27.2 0.99 517 4.5 26.5 1.00 1078
SD(D) 0.2 0.2 0.03 0 0.1 0.02 76 0.2 0.03 135
CV(E) 3.9 3.4 2.9 2.5 2.3 14.7 4.7 3.1 12.5
14 TO 52 WEEKS
----------------
MEAN 4.6 40.5 4.6 41.0 1.02 0 4.5 40.6 0.99 346 4.5 38.3 1.00 748
SD(D) 0.2 0.2 0.01 0 0.2 0.02 29 0.2 0.03 80
CV(E) 3.8 4.4 1.5 4.7 1.6 8.3 4.6 3.1 10.8
> 52 WEEKS
----------------
MEAN 4.6 40.0 4.7 41.0 1.02 0 4.5 39.3 0.98 363 4.6 36.9 1.00 787
SD(D) 0.2 0.1 0.03 0 0.2 0.03 52 0.2 0.03 115
CV(E) 4.2 2.9 2.6 5.1 2.7 14.3 5.4 2.8 14.7
==================================================================================================================================
(A) GRAMS OF FEED CONSUMED PER ANIMAL PER DAY.
(B) GRAMS OF FEED PER DAY FOR THE DOSED GROUP DIVIDED BY THAT FOR THE CONTROLS.
(C) MILLIGRAMS OF COMPOUND CONSUMED PER DAY PER KILOGRAM BODY WEIGHT.
(D) STANDARD DEVIATION OF WEEKLY MEAN.
(E) COEFFICIENT OF VARIATION = (STANDARD DEVIATION / MEAN) X 100.
FEED AND COMPOUND CONSUMPTION BY MALE MICE IN THE
CHRONIC DOSED FEED STUDY OF TRANS-CINNAMALDEHYDE
==========================================
1.25%
---------------------------------
DOSE/
GRAMS BODY CONTROL
FEED/ WEIGHT FEED (B) DOSE/
WEEK DAY(A) (GRAMS) (GRAMS) DAY(C)
==========================================
2 4.3 22.0 0.96 2459
6 4.5 24.5 1.00 2283
9 4.8 27.5 1.02 2200
13 4.4 29.0 1.02 1881
18 4.5 31.8 1.00 1767
22 4.7 33.2 1.04 1755
26 4.4 35.7 0.98 1549
30 4.3 36.8 1.02 1443
34 4.2 38.1 0.93 1391
38 4.7 38.1 0.98 1539
42 4.3 38.1 0.96 1410
46 4.6 38.6 0.96 1506
50 4.5 40.3 1.00 1403
54 4.4 41.0 0.96 1356
58 4.3 40.9 0.93 1326
62 4.4 40.1 0.98 1385
66 4.5 39.0 0.98 1431
70 4.3 38.2 0.91 1411
74 4.3 36.3 0.91 1465
78 4.3 32.8 1.00 1645
82 4.7 32.0 0.98 1845
86 4.8 31.6 0.98 1898
90 4.6 32.3 0.94 1779
94 4.1 32.1 0.98 1601
98 4.3 32.0 0.96 1669
102 4.3 32.1 0.96 1671
1 TO 13 WEEKS
----------------
MEAN 4.5 25.7 1.00 2206
SD(D) 0.2 0.03 242
CV(E) 5.1 3.1 11.0
14 TO 52 WEEKS
----------------
MEAN 4.5 36.7 0.99 1529
SD(D) 0.2 0.04 144
CV(E) 4.0 3.6 9.4
> 52 WEEKS
----------------
MEAN 4.4 35.4 0.96 1576
SD(D) 0.2 0.03 193
CV(E) 4.4 2.8 12.3
==========================================
(A) GRAMS OF FEED CONSUMED PER ANIMAL PER DAY.
(B) GRAMS OF FEED PER DAY FOR THE DOSED GROUP DIVIDED BY THAT FOR THE CONTROLS.
(C) MILLIGRAMS OF COMPOUND CONSUMED PER DAY PER KILOGRAM BODY WEIGHT.
(D) STANDARD DEVIATION OF WEEKLY MEAN.
(E) COEFFICIENT OF VARIATION = (STANDARD DEVIATION / MEAN) X 100.
FEED AND COMPOUND CONSUMPTION BY FEMALE MICE IN THE
CHRONIC DOSED FEED STUDY OF TRANS-CINNAMALDEHYDE
==================================================================================================================================
UNTREATDCONTROL VEHICLE CONTROL .312% .625%
---------------- --------------------------------- --------------------------------- ---------------------------------
DOSE/ DOSE/ DOSE/
GRAMS BODY GRAMS BODY CONTROL GRAMS BODY CONTROL GRAMS BODY CONTROL
FEED/ WEIGHT FEED/ WEIGHT FEED (B) DOSE/ FEED/ WEIGHT FEED (B) DOSE/ FEED/ WEIGHT FEED (B) DOSE/
WEEK DAY(A) (GRAMS) DAY(A) (GRAMS) (GRAMS) DAY(C) DAY(A) (GRAMS) (GRAMS) DAY(C) DAY(A) (GRAMS) (GRAMS) DAY(C)
==================================================================================================================================
1 3.5 17.9 3.3 17.9 0.94 0 3.1 17.6 0.89 541 3.2 17.9 0.91 1129
2 3.6 18.8 3.5 18.8 0.97 0 3.6 18.4 1.00 611 3.5 18.5 0.97 1177
6 3.9 22.0 3.2 20.6 0.82 0 3.9 21.5 1.00 564 3.5 20.5 0.90 1065
9 4.1 24.7 4.1 24.6 1.00 0 4.2 24.4 1.02 534 4.1 23.9 1.00 1070
13 4.3 28.0 4.1 27.4 0.95 0 4.3 27.1 1.00 495 4.2 26.5 0.98 1001
18 4.2 31.5 4.6 31.5 1.10 0 4.5 31.1 1.07 449 4.6 29.7 1.10 965
22 4.7 34.1 4.3 33.8 0.91 0 4.7 33.4 1.00 440 4.8 32.5 1.02 920
26 4.7 35.8 4.5 36.5 0.96 0 4.7 36.1 1.00 410 4.8 35.5 1.02 836
30 4.2 36.8 4.2 36.2 1.00 0 3.9 36.3 0.93 338 4.2 35.3 1.00 735
34 4.5 39.6 4.6 39.5 1.02 0 4.6 38.9 1.02 373 4.8 38.4 1.07 779
38 4.4 39.9 4.3 40.0 0.98 0 4.3 38.8 0.98 346 4.3 38.3 0.98 700
42 4.3 40.8 4.5 40.8 1.05 0 4.4 39.7 1.02 347 4.4 38.9 1.02 712
46 4.9 41.6 4.8 41.8 0.98 0 4.5 40.4 0.92 351 4.6 39.2 0.94 740
50 4.6 42.8 4.4 43.2 0.96 0 4.3 41.7 0.93 323 4.2 40.1 0.91 652
54 4.6 43.7 4.8 44.2 1.04 0 4.7 43.2 1.02 341 4.8 41.8 1.04 717
58 4.4 44.7 4.4 45.2 1.00 0 4.4 44.1 1.00 313 4.4 42.7 1.00 644
62 4.4 44.9 4.5 45.4 1.02 0 4.6 44.0 1.05 329 4.6 41.9 1.05 680
66 4.4 44.2 4.3 43.4 0.98 0 4.3 43.2 0.98 314 4.5 40.9 1.02 694
70 4.7 45.2 4.5 44.8 0.96 0 4.8 43.3 1.02 348 4.2 40.7 0.89 652
74 5.0 45.3 5.0 46.0 1.00 0 4.9 43.9 0.98 351 4.9 40.9 0.98 748
78 4.2 42.7 3.8 42.7 0.90 0 4.3 41.2 1.02 322 4.2 37.1 1.00 712
82 4.3 40.8 4.3 40.2 1.00 0 4.4 39.9 1.02 347 4.6 34.8 1.07 834
86 4.7 39.6 4.6 40.0 0.98 0 4.6 39.6 0.98 361 5.0 34.1 1.06 922
90 4.8 37.8 4.9 39.2 1.02 0 5.0 38.3 1.04 404 4.9 34.1 1.02 892
94 4.4 38.8 4.1 39.0 0.93 0 4.5 37.7 1.02 372 5.0 34.7 1.14 894
98 4.9 40.2 5.0 40.9 1.02 0 4.7 39.2 0.96 376 5.0 35.5 1.02 883
102 4.7 39.6 4.8 40.4 1.02 0 4.7 39.0 1.00 378 4.7 35.0 1.00 843
1 TO 13 WEEKS
----------------
MEAN 3.9 22.3 3.6 21.9 0.94 0 3.8 21.8 0.98 549 3.7 21.5 0.95 1088
SD(D) 0.3 0.4 0.07 0 0.5 0.05 43 0.4 0.04 67
CV(E) 8.9 11.6 7.4 13.0 5.6 7.8 11.7 4.6 6.2
14 TO 52 WEEKS
----------------
MEAN 4.5 38.1 4.5 38.1 0.99 0 4.5 37.4 0.99 375 4.5 36.4 1.01 782
SD(D) 0.2 0.2 0.05 0 0.3 0.05 46 0.3 0.06 105
CV(E) 5.2 3.8 5.4 5.6 5.2 12.3 5.6 5.7 13.4
> 52 WEEKS
----------------
MEAN 4.6 42.1 4.5 42.4 0.99 0 4.6 41.3 1.01 350 4.7 38.0 1.02 778
SD(D) 0.3 0.4 0.04 0 0.2 0.03 27 0.3 0.06 102
CV(E) 5.6 8.0 4.0 4.8 2.7 7.8 5.9 5.5 13.1
==================================================================================================================================
(A) GRAMS OF FEED CONSUMED PER ANIMAL PER DAY.
(B) GRAMS OF FEED PER DAY FOR THE DOSED GROUP DIVIDED BY THAT FOR THE CONTROLS.
(C) MILLIGRAMS OF COMPOUND CONSUMED PER DAY PER KILOGRAM BODY WEIGHT.
(D) STANDARD DEVIATION OF WEEKLY MEAN.
(E) COEFFICIENT OF VARIATION = (STANDARD DEVIATION / MEAN) X 100.
FEED AND COMPOUND CONSUMPTION BY FEMALE MICE IN THE
CHRONIC DOSED FEED STUDY OF TRANS-CINNAMALDEHYDE
==========================================
1.25%
---------------------------------
DOSE/
GRAMS BODY CONTROL
FEED/ WEIGHT FEED (B) DOSE/
WEEK DAY(A) (GRAMS) (GRAMS) DAY(C)
==========================================
1 3.1 17.9 0.89 2205
2 3.3 18.5 0.92 2259
6 3.9 21.1 1.00 2305
9 4.0 23.8 0.98 2119
13 4.3 25.7 1.00 2083
18 4.3 28.6 1.02 1875
22 4.9 30.5 1.04 2012
26 4.9 33.1 1.04 1849
30 4.1 33.7 0.98 1537
34 4.5 35.9 1.00 1579
38 4.5 36.3 1.02 1558
42 4.6 36.7 1.07 1548
46 4.7 37.0 0.96 1591
50 4.3 38.5 0.93 1386
54 5.0 39.5 1.09 1585
58 4.0 38.8 0.91 1299
62 5.0 38.3 1.14 1617
66 4.6 37.8 1.05 1515
70 4.6 38.3 0.98 1491
74 4.8 37.7 0.96 1576
78 4.4 34.8 1.05 1572
82 5.1 33.3 1.19 1926
86 5.2 33.1 1.11 1979
90 4.9 33.3 1.02 1840
94 4.3 33.5 0.98 1596
98 4.5 33.6 0.92 1667
102 4.7 34.2 1.00 1718
1 TO 13 WEEKS
----------------
MEAN 3.7 21.4 0.96 2194
SD(D) 0.5 0.05 93
CV(E) 12.7 5.4 4.2
14 TO 52 WEEKS
----------------
MEAN 4.5 34.5 1.01 1660
SD(D) 0.3 0.04 203
CV(E) 5.9 4.4 12.3
> 52 WEEKS
----------------
MEAN 4.7 35.9 1.03 1645
SD(D) 0.4 0.08 185
CV(E) 7.5 8.1 11.3
==========================================
(A) GRAMS OF FEED CONSUMED PER ANIMAL PER DAY.
(B) GRAMS OF FEED PER DAY FOR THE DOSED GROUP DIVIDED BY THAT FOR THE CONTROLS.
(C) MILLIGRAMS OF COMPOUND CONSUMED PER DAY PER KILOGRAM BODY WEIGHT.
(D) STANDARD DEVIATION OF WEEKLY MEAN.
(E) COEFFICIENT OF VARIATION = (STANDARD DEVIATION / MEAN) X 100.
DIAGNOSTIC TRAILER REPORT
FEED AND COMPOUND CONSUMPTION BY MALE MICE IN THE
CHRONIC DOSED FEED STUDY OF TRANS-CINNAMALDEHYDE
==================================================================================================================================
UNTREATDCONTROL VEHICLE CONTROL .312% .625% 1.25%
---------------------- ---------------------- ---------------------- ---------------------- ----------------------
DAILY FEED BODY NUM DAILY FEED BODY NUM DAILY FEED BODY NUM DAILY FEED BODY NUM DAILY FEED BODY NUM
WEEK FEED HOURS WGT WGTS FEED HOURS WGT WGTS FEED HOURS WGT WGTS FEED HOURS WGT WGTS FEED HOURS WGT WGTS
===================================================================================================================================
B 20.6 50 21.1 50 20.8 50 20.6 50 20.6 50
1 20.6 50 21.1 50 20.8 50 20.6 50 20.6 50
2 4.5 8183 22.2 50 4.4 8198 22.8 50 4.4 8208 22.4 50 4.3 8245 22.0 50 4.3 8245 22.0 50
5 6.4 27 7.1 27
6 4.5 8181 25.6 50 4.5 8265 25.8 50 4.4 8294 25.9 50 4.5 8346 25.3 50 4.5 8363 24.5 50
9 4.7 8391 29.3 50 4.8 8394 29.9 50 4.6 8239 29.2 49 4.8 8312 28.3 50 4.8 8403 27.5 50
13 4.3 8400 31.8 50 4.5 8400 32.3 50 4.4 8252 31.5 49 4.4 8450 30.3 50 4.4 8468 29.0 50
18 4.5 8431 34.8 50 4.5 8239 35.4 49 4.3 8254 34.5 49 4.7 8450 32.4 50 4.5 8466 31.8 50
22 4.5 8412 36.8 50 4.6 8256 36.9 49 4.5 8261 36.7 49 4.7 8459 34.4 50 4.7 8431 33.2 50
26 4.5 8338 38.9 50 4.5 8188 39.1 49 4.5 8205 39.0 49 4.4 8400 36.4 50 4.4 8433 35.7 50
30 4.2 8428 40.2 49 4.3 8428 40.6 49 4.1 8428 40.5 49 4.2 8600 38.2 50 4.3 8557 36.8 50
34 4.5 8363 42.0 49 4.5 8378 42.5 49 4.4 8379 42.4 49 4.4 8572 39.9 50 4.2 8592 38.1 50
38 4.8 8164 42.2 49 4.9 8215 42.6 49 4.8 8232 42.2 49 4.7 8433 40.1 50 4.7 8435 38.1 50
42 4.5 8318 42.2 49 4.6 8355 43.0 49 4.5 8373 42.6 49 4.3 8551 40.0 50 4.3 8583 38.1 50
46 4.8 8281 43.0 49 4.9 8330 43.7 49 4.8 8303 43.2 49 4.8 8497 40.7 50 4.6 8498 38.6 50
50 4.5 8186 44.2 48 4.7 8271 45.4 49 4.5 8247 44.6 49 4.6 8367 42.4 50 4.5 8306 40.3 50
54 4.6 8064 45.3 48 4.7 8221 46.0 49 4.6 8232 45.3 49 4.6 8232 43.1 49 4.4 8412 41.0 50
58 4.6 8084 45.5 48 4.6 8249 46.5 49 4.5 8122 45.9 49 4.6 8186 43.2 49 4.3 8361 40.9 50
62 4.5 8095 44.5 48 4.7 8281 46.1 49 4.4 8306 45.1 49 4.5 8319 42.1 49 4.4 8476 40.1 50
66 4.6 8107 43.6 48 4.7 8279 45.1 49 4.6 8281 44.0 49 4.6 8330 41.1 49 4.5 8472 39.0 50
70 4.7 8035 43.5 48 4.8 8190 44.8 49 4.7 8195 43.8 49 4.6 8227 40.5 49 4.3 8400 38.2 50
74 4.7 7896 43.1 47 4.7 8235 43.8 49 4.4 8260 42.4 49 4.4 8106 39.0 48 4.3 8495 36.3 50
78 4.3 7755 39.6 46 4.6 8344 40.5 49 4.0 8337 38.3 49 4.3 7779 35.0 46 4.3 8455 32.8 50
82 4.8 7590 38.3 46 4.9 8098 38.9 49 4.7 8107 36.8 49 4.9 7290 33.6 44 4.7 8283 32.0 50
86 4.9 7716 37.4 46 4.9 8064 37.9 48 4.8 8064 35.6 48 4.9 7224 32.6 43 4.8 8232 31.6 50
90 4.9 7797 34.7 46 4.8 8204 35.4 48 4.9 8208 33.4 48 5.1 7184 32.1 43 4.6 8379 32.3 49
94 4.2 7640 34.6 46 4.5 7997 35.9 48 4.3 7847 33.7 47 4.3 6867 32.6 41 4.1 8232 32.1 49
98 4.5 7627 34.6 45 4.6 8163 36.0 48 4.4 8014 33.2 47 4.3 7011 32.2 41 4.3 8386 32.0 49
102 4.5 7476 34.8 44 4.6 8038 35.6 47 4.3 7872 33.1 46 4.5 6684 32.3 39 4.3 8423 32.1 49
==================================================================================================================================
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
DIAGNOSTIC TRAILER REPORT
FEED AND COMPOUND CONSUMPTION BY FEMALE MICE IN THE
CHRONIC DOSED FEED STUDY OF TRANS-CINNAMALDEHYDE
==================================================================================================================================
UNTREATDCONTROL VEHICLE CONTROL .312% .625% 1.25%
---------------------- ---------------------- ---------------------- ---------------------- ----------------------
DAILY FEED BODY NUM DAILY FEED BODY NUM DAILY FEED BODY NUM DAILY FEED BODY NUM DAILY FEED BODY NUM
WEEK FEED HOURS WGT WGTS FEED HOURS WGT WGTS FEED HOURS WGT WGTS FEED HOURS WGT WGTS FEED HOURS WGT WGTS
===================================================================================================================================
B 17.9 50 17.9 50 17.6 50 17.9 50 17.9 50
1 3.5 4860 17.9 50 3.3 4860 17.9 50 3.1 4855 17.6 50 3.2 4860 17.9 50 3.1 4865 17.9 50
2 3.6 3420 18.8 50 3.5 3425 18.8 50 3.6 3430 18.4 50 3.5 3439 18.5 50 3.3 3445 18.5 50
5 3.6 4735 3.7 4750 3.5 4740 3.5 4745 3.4 4745
6 3.9 3601 22.0 50 3.2 3608 20.6 50 3.9 3618 21.5 50 3.5 3639 20.5 50 3.9 3653 21.1 50
9 4.1 8470 24.7 50 4.1 8485 24.6 50 4.2 8494 24.4 50 4.1 8501 23.9 50 4.0 8506 23.8 50
13 4.3 8427 28.0 50 4.1 8436 27.4 50 4.3 8443 27.1 50 4.2 8455 26.5 50 4.3 8464 25.7 50
17 4.1 4640 4.3 4635 4.1 4640 4.5 4635 4.3 4640
18 4.2 3603 31.5 50 4.6 3614 31.5 50 4.5 3621 31.1 50 4.6 3632 29.7 50 4.3 3643 28.6 50
21 4.1 4550 4.4 4560 4.3 4560 4.7 4570 4.5 4570
22 4.7 3612 34.1 50 4.3 3622 33.8 50 4.7 3637 33.4 50 4.8 3649 32.5 50 4.9 3662 30.5 50
25 4.4 4630 4.4 4630 4.2 4630 4.3 4630 4.6 4630
26 4.7 3636 35.8 50 4.5 3648 36.5 50 4.7 3662 36.1 50 4.8 3671 35.5 50 4.9 3680 33.1 50
29 3.8 4895 4.1 4900 3.8 4900 4.0 4860 3.9 4868
30 4.2 3575 36.8 50 4.2 3587 36.2 50 3.9 3599 36.3 50 4.2 3611 35.3 50 4.1 3625 33.7 50
33 4.2 4890 4.2 4890 4.1 4891 4.2 4900 4.0 4826
34 4.5 3715 39.6 50 4.6 3686 39.5 50 4.6 3645 38.9 50 4.8 3654 38.4 50 4.5 3531 35.9 49
37 3.6 5060 3.7 5085 3.6 5068 3.6 5055 4.0 4939
38 4.4 3348 39.9 50 4.3 3342 40.0 50 4.3 3373 38.8 50 4.3 3401 38.3 50 4.5 3358 36.3 49
41 4.3 4855 4.2 4860 4.2 4860 4.3 4865 4.3 4768
42 4.3 3571 40.8 50 4.5 3578 40.8 50 4.4 3585 39.7 50 4.4 3594 38.9 50 4.6 3524 36.7 49
45 4.3 4790 4.1 4790 4.1 4790 4.2 4765 4.2 4645
46 4.9 3639 41.6 50 4.8 3658 41.8 50 4.5 3686 40.4 50 4.6 3732 39.2 50 4.7 3680 37.0 49
49 3.9 4777 4.1 4770 4.0 4655 4.0 4750 4.1 4646
50 4.6 3712 42.8 50 4.4 3731 43.2 50 4.3 3671 41.7 49 4.2 3758 40.1 50 4.3 3695 38.5 49
53 3.9 5000 4.0 5000 4.1 4861 4.1 4960 4.1 4861
54 4.6 3465 43.7 50 4.8 3477 44.2 50 4.7 3421 43.2 49 4.8 3502 41.8 50 5.0 3442 39.5 49
57 4.2 4670 3.8 4670 4.3 4577 4.2 4620 4.2 4437
58 4.4 3812 44.7 50 4.4 3825 45.2 50 4.4 3773 44.1 49 4.4 3839 42.7 50 4.0 3653 38.8 48
61 4.0 4835 3.9 4840 4.0 4743 3.9 4840 4.3 4646
62 4.4 3458 44.9 50 4.5 3477 45.4 50 4.6 3426 44.0 49 4.6 3442 41.9 49 5.0 3391 38.3 48
65 3.9 4772 3.9 4860 4.0 4766 4.1 4763 4.4 4666
66 4.4 3631 44.2 49 4.3 3720 43.4 49 4.3 3663 43.2 49 4.5 3677 40.9 49 4.6 3614 37.8 48
69 4.2 4685 4.1 4490 4.1 4684 3.8 4679 4.4 4578
70 4.7 3378 45.2 49 4.5 3251 44.8 47 4.8 3398 43.3 49 4.2 3443 40.7 49 4.6 3383 38.3 48
73 4.1 4988 4.0 4789 4.1 4993 4.1 4993 3.9 4896
74 5.0 3225 45.3 49 5.0 3103 46.0 47 4.9 3247 43.9 49 4.9 3258 40.9 49 4.8 3200 37.7 48
77 4.0 4637 4.0 4542 3.8 4910 3.5 4910 3.8 4812
78 4.2 3456 42.7 48 3.8 3392 42.7 47 4.3 3386 41.2 49 4.2 3396 37.1 49 4.4 3338 34.8 48
81 4.1 4626 4.0 4527 4.1 4522 4.0 4710 4.5 4608
82 4.3 3406 40.8 48 4.3 3067 40.2 47 4.4 3370 39.9 47 4.6 3531 34.8 49 5.1 3476 33.3 48
85 3.8 4618 4.1 4440 4.1 4434 3.9 4633 4.1 4441
86 4.7 3450 39.6 48 4.6 3286 40.0 46 4.6 3245 39.6 45 5.0 3377 34.1 48 5.2 3238 33.1 46
89 4.2 4642 4.3 4258 4.2 4355 4.4 4646 4.2 4459
90 4.8 3329 37.8 48 4.9 3090 39.2 44 5.0 3164 38.3 45 4.9 3380 34.1 48 4.9 3243 33.3 46
93 3.6 4627 3.8 4424 3.7 4429 3.8 4622 3.5 4501
94 4.4 3083 38.8 46 4.1 2966 39.0 44 4.5 2977 37.7 44 5.0 3122 34.7 46 4.3 3064 33.5 45
97 4.3 4170 4.4 4223 4.6 3840 4.3 4416 4.1 4322
98 4.9 3138 40.2 43 5.0 3227 40.9 44 4.7 2946 39.2 40 5.0 3397 35.5 46 4.5 3337 33.6 45
101 4.1 4186 4.4 4088 4.4 3894 4.4 4384 4.2 4288
==================================================================================================================================
DIAGNOSTIC TRAILER REPORT
FEED AND COMPOUND CONSUMPTION BY FEMALE MICE IN THE
CHRONIC DOSED FEED STUDY OF TRANS-CINNAMALDEHYDE
==================================================================================================================================
UNTREATDCONTROL VEHICLE CONTROL .312% .625% 1.25%
---------------------- ---------------------- ---------------------- ---------------------- ----------------------
DAILY FEED BODY NUM DAILY FEED BODY NUM DAILY FEED BODY NUM DAILY FEED BODY NUM DAILY FEED BODY NUM
WEEK FEED HOURS WGT WGTS FEED HOURS WGT WGTS FEED HOURS WGT WGTS FEED HOURS WGT WGTS FEED HOURS WGT WGTS
===================================================================================================================================
102 4.7 3069 39.6 43 4.8 3008 40.4 42 4.7 2875 39.0 40 4.7 3250 35.0 45 4.7 3190 34.2 44
==================================================================================================================================
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.