TDMS Study 56348-04 Pathology Tables
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: Battelle Columbus CITRAL DATE: 07/05/01
EXPERIMENT: 56348 TEST: 04 TIME: 13:40:02
CAGES FROM 0000 TO LAST CAGE PAGE: 1
TEST TYPE: CHRONIC ROUTE: DOSED FEED NTP: C56348
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REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: BATTELLE COLUMBUS LABORATORY CITRAL DATE: 07/05/01
EXPERIMENT: 56348 TEST: 04 TIME: 13:51:57
SPECIES: MICE, B6C3F1
TEST TYPE: TWO YEAR ROUTE: DOSED FEED NTP: C56348
CONT: N01-ES-55384 CAS: 5392-40-5
MEAN BODY WEIGHTS AND SURVIVAL OF MALE MICE IN THE
TWO YEAR DOSED FEED STUDY OF CITRAL
===================================================================================================================================
WEEK UNTREAT CONTROL VEHICLE CONTROL 500 PPM 1000 PPM 2000 PPM
---------------- ---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
==================================================================================================================================
B 21.6 50 21.7 100.5 50 21.8 100.9 50 21.7 100.5 50 21.7 100.5 50
1 21.6 50 21.7 100.5 50 21.8 100.9 50 21.7 100.5 50 21.7 100.5 50
2 22.0 50 22.3 101.4 50 22.4 101.8 50 21.8 99.1 50 21.5 97.7 50
6 25.9 50 26.8 103.5 50 26.5 102.3 50 26.0 100.4 50 25.4 98.1 50
10 29.5 50 30.4 103.1 50 30.1 102.0 50 29.2 99.0 50 28.1 95.3 50
14 31.9 50 32.9 103.1 50 32.4 101.6 50 31.6 99.1 50 30.5 95.6 50
18 33.8 50 34.2 101.2 50 34.0 100.6 50 33.4 98.8 50 32.3 95.6 50
22 35.6 50 36.4 102.2 49 35.9 100.8 50 34.6 97.2 50 33.7 94.7 50
26 37.4 50 38.3 102.4 49 37.6 100.5 50 36.3 97.1 50 35.7 95.5 50
30 39.4 50 40.4 102.5 49 39.6 100.5 50 38.6 98.0 50 37.2 94.4 50
34 40.8 50 42.3 103.7 49 41.0 100.5 50 40.1 98.3 50 38.2 93.6 50
38 42.4 50 43.4 102.4 49 42.2 99.5 50 40.9 96.5 50 39.1 92.2 50
42 42.9 50 43.4 101.2 49 42.6 99.3 50 41.6 97.0 50 40.0 93.2 50
46 42.6 50 43.9 103.1 48 43.1 101.2 50 41.7 97.9 50 39.9 93.7 50
50 43.5 50 45.1 103.7 48 44.0 101.1 50 42.7 98.2 50 40.6 93.3 50
54 44.1 50 44.9 101.8 48 43.5 98.6 50 42.6 96.6 50 40.4 91.6 50
58 43.9 49 45.3 103.2 48 44.0 100.2 50 42.0 95.7 50 40.6 92.5 50
62 43.1 49 44.9 104.2 48 43.9 101.9 48 42.2 97.9 49 40.2 93.3 50
66 43.8 49 44.7 102.1 48 44.5 101.6 48 42.8 97.7 49 40.4 92.2 48
70 45.2 49 44.6 98.7 48 44.5 98.5 48 43.6 96.5 49 40.6 89.8 48
74 45.8 49 45.6 99.6 48 45.8 100.0 46 44.1 96.3 49 41.2 90.0 47
78 46.2 49 48.2 104.3 46 46.4 100.4 46 44.8 97.0 49 41.5 89.8 47
82 47.2 49 49.6 105.1 46 46.8 99.2 46 45.3 96.0 49 42.0 89.0 47
86 47.4 49 49.5 104.4 46 46.9 98.9 45 45.7 96.4 49 41.3 87.1 47
90 45.4 49 47.6 104.8 46 45.2 99.6 44 44.0 96.9 48 39.8 87.7 46
94 45.6 48 47.9 105.0 45 45.0 98.7 42 43.4 95.2 47 40.1 87.9 43
98 45.5 48 47.0 103.3 45 44.9 98.7 41 42.9 94.3 47 39.7 87.3 42
102 44.0 48 45.9 104.3 43 42.8 97.3 41 41.6 94.5 44 38.6 87.7 40
TERM. SAC. 48 43 40 42 40
===================================================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.
MEAN BODY WEIGHTS AND SURVIVAL OF FEMALE MICE IN THE
TWO YEAR DOSED FEED STUDY OF CITRAL
===================================================================================================================================
WEEK UNTREAT CONTROL VEHICLE CONTROL 500 PPM 1000 PPM 2000 PPM
---------------- ---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
==================================================================================================================================
B 17.9 50 17.6 98.3 50 17.7 98.9 50 17.8 99.4 50 17.6 98.3 50
1 17.9 50 17.6 98.3 50 17.7 98.9 50 17.8 99.4 50 17.6 98.3 50
2 18.3 50 18.2 99.5 50 18.1 98.9 50 18.3 100.0 50 17.9 97.8 50
6 22.7 49 22.5 99.1 50 22.5 99.1 50 22.4 98.7 50 21.7 95.6 50
10 25.7 49 26.1 101.6 50 25.3 98.4 50 25.4 98.8 50 24.6 95.7 50
14 28.1 49 28.3 100.7 50 27.8 98.9 50 26.6 94.7 50 25.7 91.5 50
18 29.2 49 31.2 106.8 49 29.8 102.1 50 29.2 100.0 50 27.9 95.5 50
22 28.8 49 31.0 107.6 49 29.8 103.5 50 29.1 101.0 50 27.8 96.5 50
26 31.5 49 33.4 106.0 49 31.6 100.3 50 31.6 100.3 50 29.5 93.7 50
30 33.5 49 35.4 105.7 49 33.4 99.7 50 33.4 99.7 50 31.0 92.5 50
34 35.6 49 37.8 106.2 49 35.1 98.6 50 35.3 99.2 50 31.9 89.6 50
38 35.9 46 38.6 107.5 49 35.5 98.9 50 35.7 99.4 50 32.6 90.8 50
42 36.1 46 39.2 108.6 49 36.5 101.1 50 35.8 99.2 50 34.0 94.2 49
46 37.1 46 37.9 102.2 49 34.5 93.0 50 34.6 93.3 50 32.4 87.3 49
50 38.0 46 40.0 105.3 49 37.0 97.4 50 36.1 95.0 50 34.2 90.0 49
54 39.4 46 40.6 103.0 49 37.5 95.2 50 36.4 92.4 50 35.0 88.8 49
58 39.8 46 41.4 104.0 49 38.5 96.7 50 37.2 93.5 50 35.3 88.7 49
62 39.9 46 41.3 103.5 49 39.0 97.7 49 37.0 92.7 50 35.6 89.2 49
66 39.9 46 41.1 103.0 48 39.0 97.7 49 37.1 93.0 50 35.1 88.0 49
70 42.2 46 41.8 99.1 47 39.2 92.9 49 38.7 91.7 49 35.6 84.4 49
74 41.7 46 42.1 101.0 47 40.0 95.9 49 38.3 91.8 49 35.4 84.9 48
78 43.9 46 44.3 100.9 47 41.5 94.5 49 39.6 90.2 49 36.4 82.9 47
82 45.9 43 46.7 101.7 47 42.8 93.2 49 41.3 90.0 49 36.9 80.4 46
86 47.4 43 47.2 99.6 47 43.4 91.6 49 41.5 87.6 48 37.5 79.1 45
90 47.2 43 46.5 98.5 47 43.6 92.4 47 41.4 87.7 47 37.0 78.4 44
94 47.2 43 47.3 100.2 45 43.8 92.8 47 42.8 90.7 45 37.6 79.7 43
98 47.5 42 48.0 101.1 44 43.5 91.6 46 42.5 89.5 45 37.6 79.2 42
102 45.9 42 47.1 102.6 43 42.9 93.5 45 41.4 90.2 45 36.6 79.7 40
TERM. SAC. 40 41 45 43 40
===================================================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.