Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:
https://ntp.niehs.nih.gov/go/7209

TDMS Study 56348-04 Pathology Tables

NTP Experiment-Test: 56348-04                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                               CITRAL                                          Date: 07/05/01
Route: DOSED FEED                                                                                                 Time: 13:38:50




       Facility:  Battelle Columbus Laboratory

       Chemical CAS #:  5392-40-5

       Lock Date:  03/25/99

       Cage Range:  All

       Reasons For Removal:    All

       Removal Date Range:     All

       Treatment Groups:       Include All






































                                                              Page   1


NTP Experiment-Test: 56348-04                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09  
Study Type: CHRONIC                                               CITRAL                                          Date: 07/05/01    
Route: DOSED FEED                                                                                                 Time: 13:38:50    
 _____________________________________________________________________________________________________________________              
                                           | 7| 2| 2| 2| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 7| 7| 5| 7| 5| 7| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 4| 4| 4| 3| 0| 3| 3| 3| 3| 3| 3| 3| 5| 3| 3| 4| 3| 4| 3| 3| 3| 3| 3| 3|             
                                           | 4| 3| 2| 2| 3| 9| 4| 5| 5| 3| 5| 3| 3| 7| 4| 4| 5| 4| 4| 5| 4| 4| 5| 4| 3|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    UNTREAT                                | 5| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7|             
    CONTROL                                | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |__________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Gallbladder                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
                                           |__________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Ectasia                              |                3                                                         |             
      Inflammation, Chronic                |                                                                          |             
      Epithelium, Hyperplasia, Focal       |                                                                      1   |             
      Epithelium, Metaplasia, Squamous     |                                                                      1   |             
                                           |__________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Peyer's Patch, Hyperplasia, Lymphoid |                                                                          |             
                                           |__________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Inflammation, Chronic                |                                                                          |             
      Inflammation, Granulomatous          |                                                                          |             
      Ulcer                                |                                                                          |             
                                           |__________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Clear Cell Focus                     |                                     X                                    |             
      Hematopoietic Cell Proliferation     |                2                                                         |             
      Infiltration Cellular, Lymphocyte    |                   1  1  1  1     1  1     1                 1        1   |             
      Inflammation, Granulomatous          | 1        1  1  1     1  1        1           1     1     1  1     1      |             
      Mixed Cell Focus                     |                                                             X            |             
      Necrosis, Focal                      |    2  2                                                                  |             
      Vacuolization Cytoplasmic, Focal     | 1        1                                                     1  1      |             
      Bile Duct, Inflammation,             |                                                                          |             
          Granulomatous                    |                                                                          |             
      Centrilobular, Degeneration          |                                                                          |             
                                           |__________________________________________________________________________|             
   Mesentery                               |                +              +        +     +                           |             
 __________________________________________|__________________________________________________________________________|             
                                                                                                                                    
                                                                                                                                    
                                                             Page   2                                                               
                                                                                                                                   
NTP Experiment-Test: 56348-04                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09  
Study Type: CHRONIC                                               CITRAL                                          Date: 07/05/01    
Route: DOSED FEED                                                                                                 Time: 13:38:50    
 _____________________________________________________________________________________________________________________              
                                           | 7| 2| 2| 2| 7| 7| 7| 7| 7| 7| 7| 7| 7| 5| 7| 7| 5| 7| 5| 7| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 4| 4| 4| 3| 0| 3| 3| 3| 3| 3| 3| 3| 5| 3| 3| 4| 3| 4| 3| 3| 3| 3| 3| 3|             
                                           | 4| 3| 2| 2| 3| 9| 4| 5| 5| 3| 5| 3| 3| 7| 4| 4| 5| 4| 4| 5| 4| 4| 5| 4| 3|             
 __________________________________________|__________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    UNTREAT                                | 5| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 7|             
    CONTROL                                | 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5| 6| 7| 8| 9| 0| 1| 2| 3| 4| 5|             
 __________________________________________|__________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
      Infiltration Cellular, Mast Cell     |                                                                          |             
      Inflammation, Granulomatous          |                                              2                           |             
      Fat, Necrosis                        |                4              1        2                                 |             
                                           |__________________________________________________________________________|             
   Oral Mucosa                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Infiltration Cellular, Mast Cell     |                                                                          |             
      Inflammation, Chronic Active         | 2                 1              2     1        2  2     1     1  2      |             
      Ulcer                                | 2                                               1                 1      |             
                                           |__________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +|             
      Infiltration Cellular, Mast