TDMS Study 88007-06 Pathology Tables
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41 LAB: Battelle Columbus SODIUM NITRITE DATE: 05/13/99 EXPERIMENT: 88007 TEST: 06 TIME: 09:30:12 CAGES FROM 0000 TO LAST CAGE PAGE: 1 TEST TYPE: CHRONIC ROUTE: DOSED WATER NTP: C88007 CONT: NO1-ES-55384 CAS: 7632-00-0 ------------------------------------------------------------------------------------------------------------------------------------ REASONS FOR REMOVAL: ALL REMOVAL DATE RANGE: ALL TREATMENT GROUPS: INCLUDE ALL NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41 LAB: BATTELLE COLUMBUS LABORATORY SODIUM NITRITE DATE: 05/13/99 EXPERIMENT: 88007 TEST: 06 TIME: 9:36:35 TEST TYPE: TWO YEAR ROUTE: DOSED WATER NTP: C88007 CONT: NO1-ES-55384 CAS: 7632-00-0 MEAN BODY WEIGHTS AND SURVIVAL OF MALE MICE IN THE TWO YEAR DOSED WATER STUDY OF SODIUM NITRITE ========================================================================================================== WEEK 0.0% 0.075% 0.15% 0.30% ---------------- ---------------- ---------------- ---------------- AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. (GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) ========================================================================================================= B 22.6 50 22.7 100.4 50 22.6 100.0 50 22.6 100.0 50 1 22.6 50 22.7 100.4 50 22.6 100.0 50 22.6 100.0 50 2 23.7 50 23.7 100.0 50 23.6 99.6 50 23.4 98.7 50 6 29.5 50 29.6 100.3 50 29.1 98.6 50 28.3 95.9 50 10 34.9 50 34.5 98.9 50 33.7 96.6 50 32.7 93.7 50 14 39.1 50 38.9 99.5 50 37.7 96.4 50 36.2 92.6 50 18 43.2 50 42.9 99.3 50 41.9 97.0 50 40.2 93.1 50 22 45.6 50 44.9 98.5 50 44.0 96.5 50 42.1 92.3 50 26 47.5 50 46.6 98.1 50 45.7 96.2 50 44.6 93.9 50 30 49.6 50 48.9 98.6 50 48.3 97.4 50 46.9 94.6 50 34 50.8 50 50.1 98.6 50 49.2 96.9 50 48.4 95.3 50 38 50.6 50 49.7 98.2 50 48.7 96.2 50 48.1 95.1 50 42 50.9 50 49.9 98.0 50 48.4 95.1 50 48.6 95.5 50 46 50.8 50 49.4 97.2 50 48.3 95.1 50 48.6 95.7 50 50 50.3 50 49.0 97.4 50 48.0 95.4 50 48.3 96.0 50 54 51.3 50 50.5 98.4 50 49.2 95.9 50 49.5 96.5 50 58 51.1 50 49.6 97.1 50 49.3 96.5 50 49.8 97.5 50 62 51.4 50 50.4 98.1 50 49.4 96.1 50 49.5 96.3 50 66 50.7 50 49.8 98.2 49 49.0 96.6 50 48.8 96.3 50 70 50.0 50 49.7 99.4 49 48.8 97.6 50 48.7 97.4 49 73 49.4 49 49.5 100.2 49 48.8 98.8 50 48.1 97.4 48 78 49.4 48 49.1 99.4 49 48.2 97.6 50 47.6 96.4 48 82 48.7 48 48.4 99.4 49 48.2 99.0 50 46.6 95.7 46 86 47.2 48 46.9 99.4 49 46.8 99.2 48 45.4 96.2 44 90 46.4 47 46.4 100.0 47 46.1 99.4 48 44.7 96.3 44 94 44.7 45 44.4 99.3 45 44.5 99.6 45 44.1 98.7 43 98 43.0 43 43.7 101.6 45 43.6 101.4 43 42.8 99.5 41 102 40.2 40 41.3 102.7 45 41.4 103.0 42 41.0 102.0 39 TERM. SAC. 39 45 42 39 ========================================================================================================== (A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE. (B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT. (I) INTERIM SACRIFICE OCCURRED IN THIS WEEK. (*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK IS LESS THAN THE NUMBER OF ANIMALS SURVIVING. MEAN BODY WEIGHTS AND SURVIVAL OF FEMALE MICE IN THE TWO YEAR DOSED WATER STUDY OF SODIUM NITRITE ========================================================================================================== WEEK 0.0% 0.075% 0.15% 0.30% ---------------- ---------------- ---------------- ---------------- AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. (GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) ========================================================================================================= B 18.9 50 18.9 100.0 50 18.8 99.5 50 18.9 100.0 50 1 18.9 50 18.9 100.0 50 18.8 99.5 50 18.9 100.0 50 2 19.4 50 19.7 101.5 50 19.5 100.5 50 19.4 100.0 50 6 23.7 50 23.9 100.8 50 23.9 100.8 50 23.2 97.9 50 10 28.2 50 28.4 100.7 50 28.2 100.0 50 26.9 95.4 50 14 31.4 50 32.6 103.8 50 31.5 100.3 50 30.3 96.5 50 18 35.6 50 37.8 106.2 50 36.5 102.5 50 34.4 96.6 50 22 40.0 50 41.7 104.3 50 40.6 101.5 50 38.2 95.5 50 26 43.2 50 44.9 103.9 50 43.7 101.2 50 41.1 95.1 50 30 46.6 50 47.4 101.7 50 46.2 99.1 50 43.3 92.9 50 34 49.2 50 49.6 100.8 50 48.8 99.2 50 45.4 92.3 50 38 51.1 50 51.1 100.0 50 50.0 97.8 50 46.9 91.8 50 42 53.4 50 53.3 99.8 50 52.3 97.9 50 48.8 91.4 50 46 54.2 50 54.6 100.7 50 54.0 99.6 50 50.8 93.7 50 50 55.3 50 55.6 100.5 50 54.8 99.1 50 52.5 94.9 50 54 56.1 50 55.3 98.6 50 55.2 98.4 50 53.0 94.5 50 58 56.7 50 57.0 100.5 50 56.6 99.8 50 54.2 95.6 50 62 58.8 50 58.2 99.0 50 58.4 99.3 50 56.1 95.4 49 66 58.3 49 57.5 98.6 50 57.4 98.5 50 55.4 95.0 49 70 57.7 49 56.8 98.4 49 56.5 97.9 49 54.4 94.3 48 73 56.1 49 56.1 100.0 49 55.0 98.0 49 53.7 95.7 48 78 55.5 49 56.3 101.4 49 55.0 99.1 48 53.8 96.9 47 82 55.0 47 55.6 101.1 49 54.2 98.5 48 54.2 98.5 46 86 53.5 45 53.7 100.4 49 53.5 100.0 48 53.2 99.4 46 90 52.6 43 52.8 100.4 48 53.1 101.0 45 51.2 97.3 46 94 52.1 42 52.1 100.0 43 52.3 100.4 45 49.6 95.2 46 98 52.0 41 51.4 98.8 37 51.4 98.8 44 49.3 94.8 44 102 51.1 41 50.7 99.2 35 50.7 99.2 41 48.9 95.7 41 TERM. SAC. 40 34 37 41 ========================================================================================================== (A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE. (B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT. (I) INTERIM SACRIFICE OCCURRED IN THIS WEEK. (*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.