TDMS Study 88031-05 Pathology Tables
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: Battelle Columbus DIPROPYLENE GLYCOL DATE: 12/07/00
EXPERIMENT: 88031 TEST: 05 TIME: 10:26:17
CAGES FROM 0000 TO LAST CAGE PAGE: 1
TEST TYPE: CHRONIC ROUTE: DOSED WATER NTP: C88031
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REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: BATTELLE COLUMBUS DIPROPYLENE GLYCOL DATE: 12/07/00
EXPERIMENT: 88031 TEST: 05 TIME: 10:35:07
SPECIES: RATS, FISCHER 344
TEST TYPE: TWO YEAR ROUTE: DOSED WATER NTP: C88031
CONT: N01-ES-55388 CAS: 25265-71-8
MEAN BODY WEIGHTS AND SURVIVAL OF MALE RATS IN THE
TWO YEAR DOSED WATER STUDY OF DIPROPYLENE GLYCOL
==========================================================================================================
WEEK 0.0% 0.25% 1.0% 4.0%
---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
=========================================================================================================
B 99.8 50 100.4 100.6 50 100.2 100.4 50 101.7 101.9 50
1 99.8 50 100.4 100.6 50 100.2 100.4 50 101.7 101.9 50
2 132.7 50 132.6 99.9 50 132.5 99.8 50 122.1 92.0 50
6 251.7 50 248.1 98.6 50 247.1 98.2 50 230.5 91.6 50
10 316.3 50 311.0 98.3 50 307.9 97.3 50 282.0 89.2 50
14 360.1 50 350.2 97.3 50 344.4 95.6 50 309.1 85.8 50
18 394.6 50 386.1 97.8 50 375.4 95.1 50 339.7 86.1 50
22 420.1 50 412.2 98.1 50 400.2 95.3 50 362.9 86.4 50
26 432.3 50 426.4 98.6 50 412.0 95.3 50 375.2 86.8 50
30 449.9 50 442.6 98.4 50 426.2 94.7 50 388.0 86.2 50
34 464.1 50 455.4 98.1 50 440.9 95.0 50 398.6 85.9 50
38 471.4 50 468.1 99.3 50 451.3 95.7 50 406.4 86.2 50
42 484.3 49 482.9 99.7 50 466.8 96.4 50 416.2 85.9 50
46 489.1 49 488.5 99.9 50 470.8 96.3 50 418.0 85.5 50
50 497.5 48 494.5 99.4 50 477.8 96.0 49 419.2 84.3 50
54 503.6 48 502.2 99.7 50 485.2 96.3 49 426.5 84.7 50
58 511.8 47 510.6 99.8 50 495.3 96.8 49 424.0 82.8 49
62 518.3 47 517.4 99.8 49 501.4 96.7 49 424.6 81.9 48
66 509.7 47 511.3 100.3 48 494.9 97.1 49 415.6 81.5 45
70 513.5 47 514.7 100.2 48 499.9 97.4 49 408.0 79.5 42
74 513.3 46 520.7 101.4 47 501.0 97.6 49 404.3 78.8 39
78 510.9 46 514.1 100.6 46 493.4 96.6 49 395.4 77.4 36
82 511.3 42 512.6 100.3 42 495.1 96.8 46 386.7 75.6 29
86 514.4 39 512.9 99.7 41 489.9 95.2 43 370.9 72.1 23
90 511.8 39 513.5 100.3 40 493.6 96.4 39 350.5 68.5 12
94 509.2 37 516.6 101.5 38 495.9 97.4 34 367.1 72.1 4
98 519.6 30 514.4 99.0 36 486.0 93.5 33 330.9 63.7 2
102 513.3 25 506.4 98.7 34 489.0 95.3 31
TERM. SAC. 23 27 27 0
==========================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.
MEAN BODY WEIGHTS AND SURVIVAL OF FEMALE RATS IN THE
TWO YEAR DOSED WATER STUDY OF DIPROPYLENE GLYCOL
==========================================================================================================
WEEK 0.0% 0.25% 1.0% 4.0%
---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
=========================================================================================================
B 93.8 50 93.9 100.1 50 92.8 98.9 50 92.5 98.6 50
1 93.8 50 93.9 100.1 50 92.8 98.9 50 92.5 98.6 50
2 111.6 50 112.3 100.6 50 111.9 100.3 50 105.0 94.1 50
6 161.8 50 160.8 99.4 50 160.2 99.0 50 152.0 93.9 50
10 184.0 50 180.5 98.1 50 180.3 98.0 50 165.2 89.8 50
14 195.4 50 194.4 99.5 50 193.4 99.0 50 178.8 91.5 50
18 208.9 50 206.0 98.6 50 204.0 97.7 50 187.2 89.6 50
22 218.2 50 215.7 98.9 50 214.8 98.4 50 195.7 89.7 50
26 222.1 50 219.4 98.8 50 219.3 98.7 50 198.5 89.4 50
30 232.0 50 227.9 98.2 50 227.2 97.9 50 203.4 87.7 50
34 240.7 50 235.2 97.7 50 236.2 98.1 50 208.4 86.6 50
38 244.6 49 243.6 99.6 50 244.8 100.1 50 213.8 87.4 50
42 253.6 49 252.0 99.4 50 254.5 100.4 50 218.4 86.1 50
46 267.0 49 263.8 98.8 50 262.7 98.4 49 224.3 84.0 50
50 279.4 49 274.9 98.4 50 274.9 98.4 49 230.5 82.5 50
54 288.3 49 283.4 98.3 50 284.9 98.8 49 243.5 84.5 50
58 298.5 49 292.8 98.1 50 294.6 98.7 49 251.0 84.1 50
62 306.5 48 297.9 97.2 48 304.5 99.3 49 259.5 84.7 50
66 312.7 48 303.0 96.9 47 310.0 99.1 49 262.7 84.0 50
70 319.7 48 310.9 97.2 47 316.5 99.0 49 271.4 84.9 50
74 327.6 48 319.7 97.6 47 324.3 99.0 49 277.6 84.7 50
78 328.2 46 315.2 96.0 47 325.3 99.1 49 274.3 83.6 48
82 337.4 44 321.1 95.2 46 328.3 97.3 49 285.0 84.5 46
86 337.2 44 325.1 96.4 43 331.5 98.3 49 289.2 85.8 44
90 342.0 42 328.3 96.0 41 335.6 98.1 45 288.2 84.3 42
94 348.0 40 335.0 96.3 38 342.0 98.3 43 296.6 85.2 39
98 350.8 39 338.7 96.6 36 347.8 99.1 41 295.2 84.2 37
102 350.5 33 346.6 98.9 35 352.1 100.5 40 301.3 86.0 34
TERM. SAC. 30 31 38 31
==========================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.