TDMS Study 88036-03 Pathology Tables
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: Battelle Columbus ANTHRAQUINONE DATE: 02/25/99
EXPERIMENT: 88036 TEST: 03 TIME: 11:19:30
CAGES FROM 0000 TO LAST CAGE PAGE: 1
TEST TYPE: CHRONIC ROUTE: DOSED FEED NTP: C88036
CONT: N01-ES-25337 CAS: 84-65-1
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REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: BATTELLE COLUMBUS LABORATORY ANTHRAQUINONE DATE: 02/25/99
EXPERIMENT: 88036 TEST: 03 TIME: 11:28:58
TEST TYPE: TWO YEAR ROUTE: DOSED FEED NTP: C88036
CONT: N01-ES-25337 CAS: 84-65-1
MEAN BODY WEIGHTS AND SURVIVAL OF MALE RATS IN THE
TWO YEAR DOSED FEED STUDY OF ANTHRAQUINONE
===================================================================================================================================
WEEK 0 PPM 469 PPM 938 PPM 1875 PPM 3750 PPM
---------------- ---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
==================================================================================================================================
B 112.8 60 112.2 99.5 50 114.2 101.2 50 112.6 99.8 50 112.5 99.7 60
1 112.8 60 112.2 99.5 50 114.2 101.2 50 112.6 99.8 50 112.5 99.7 60
2 149.0 60 148.0 99.3 50 148.6 99.7 50 148.1 99.4 50 144.9 97.2 60
6 252.2 60 246.0 97.5 50 241.2 95.6 50 242.0 96.0 50 236.6 93.8 60
10 300.8 60 294.4 97.9 50 293.1 97.4 50 286.4 95.2 50 284.7 94.6 59
14 335.9 60 (I) 328.5 97.8 50 323.3 96.2 50 316.9 94.3 50 321.6 95.7 59 (I)
18 360.9 55 354.3 98.2 50 346.1 95.9 50 348.6 96.6 50 348.0 96.4 54
22 378.6 55 372.8 98.5 50 366.6 96.8 50 370.4 97.8 50 365.9 96.6 54
26 395.1 55 392.9 99.4 50 389.2 98.5 50 389.9 98.7 50 383.2 97.0 54
30 408.5 55 407.4 99.7 50 404.1 98.9 50 405.3 99.2 50 399.6 97.8 54
34 416.2 55 419.1 100.7 50 413.8 99.4 50 414.3 99.5 50 408.6 98.2 54
38 423.0 55 425.4 100.6 50 418.3 98.9 50 419.7 99.2 49 416.6 98.5 54
42 429.8 55 432.4 100.6 50 422.5 98.3 50 428.9 99.8 49 426.2 99.2 54
46 436.3 55 440.0 100.8 50 433.1 99.3 49 439.6 100.8 49 430.7 98.7 54
50 440.9 55 438.6 99.5 50 433.8 98.4 49 437.3 99.2 49 428.7 97.2 54
54 446.6 50 (I) 443.2 99.2 50 437.6 98.0 49 440.4 98.6 49 424.6 95.1 49 (I)
58 457.5 50 450.3 98.4 50 443.9 97.0 49 446.1 97.5 49 430.4 94.1 49
62 466.1 50 460.7 98.8 50 453.2 97.2 49 456.9 98.0 49 443.6 95.2 48
66 468.3 50 461.1 98.5 50 456.8 97.5 49 464.2 99.1 49 446.9 95.4 48
70 467.7 50 460.8 98.5 48 452.5 96.8 48 459.2 98.2 49 443.0 94.7 47
74 470.7 48 456.2 96.9 48 454.7 96.6 48 458.8 97.5 49 448.5 95.3 46
78 474.9 46 457.6 96.4 48 449.4 94.6 48 455.8 96.0 48 441.7 93.0 45
82 475.7 42 456.4 95.9 48 446.8 93.9 46 451.6 94.9 48 437.8 92.0 45
86 471.0 41 444.2 94.3 48 438.5 93.1 45 441.1 93.7 46 433.6 92.1 44
90 462.4 39 442.3 95.7 45 431.5 93.3 42 439.8 95.1 44 429.8 92.9 40
94 448.1 34 425.3 94.9 42 426.8 95.2 38 422.6 94.3 41 419.9 93.7 36
98 449.8 30 429.0 95.4 33 424.8 94.4 35 418.2 93.0 38 413.8 92.0 32
102 430.3 25 405.3 94.2 29 399.6 92.9 28 414.2 96.3 31 401.9 93.4 23
TERM. SAC. 22 23 22 26 22
===================================================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.
MEAN BODY WEIGHTS AND SURVIVAL OF FEMALE RATS IN THE
TWO YEAR DOSED FEED STUDY OF ANTHRAQUINONE
===================================================================================================================================
WEEK 0 PPM 469 PPM 938 PPM 1875 PPM 3750 PPM
---------------- ---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
==================================================================================================================================
B 100.7 60 101.3 100.6 50 102.0 101.3 50 100.3 99.6 50 101.6 100.9 60
1 100.7 60 101.3 100.6 50 102.0 101.3 50 100.3 99.6 50 101.6 100.9 60
2 118.3 60 118.7 100.3 50 117.4 99.2 50 116.0 98.1 50 117.3 99.2 60
6 164.6 60 160.6 97.6 50 156.0 94.8 50 156.1 94.8 50 156.7 95.2 60
10 181.8 60 176.3 97.0 50 171.3 94.2 50 168.7 92.8 50 165.8 91.2 60
14 195.4 60 (I) 186.8 95.6 50 182.3 93.3 49 184.7 94.5 50 176.7 90.4 60 (I)
18 207.6 55 198.7 95.7 50 187.3 90.2 49 190.5 91.8 50 184.2 88.7 55
22 215.1 55 201.8 93.8 50 195.2 90.7 49 191.8 89.2 50 191.1 88.8 55
26 226.4 55 209.7 92.6 50 202.6 89.5 49 198.9 87.9 50 194.6 86.0 55
30 231.2 55 213.2 92.2 50 206.4 89.3 49 203.2 87.9 50 197.2 85.3 55
34 238.0 55 218.2 91.7 50 209.1 87.9 49 204.8 86.1 50 201.5 84.7 55
38 241.6 55 213.0 88.2 50 208.8 86.4 49 205.4 85.0 50 198.7 82.2 55
42 249.7 55 225.8 90.4 50 213.5 85.5 49 209.6 83.9 50 204.0 81.7 55
46 260.7 55 232.0 89.0 50 219.0 84.0 49 213.0 81.7 50 208.6 80.0 55
50 261.1 55 233.1 89.3 50 219.4 84.0 49 214.0 82.0 50 211.0 80.8 55
54 268.5 50 (I) 238.9 89.0 50 221.7 82.6 49 218.8 81.5 50 214.0 79.7 50 (I)
58 270.7 50 246.8 91.2 50 230.2 85.0 49 225.0 83.1 50 221.8 81.9 50
62 293.1 50 261.4 89.2 50 242.9 82.9 49 234.5 80.0 50 233.5 79.7 50
66 302.4 50 267.2 88.4 50 252.0 83.3 49 245.4 81.2 50 238.3 78.8 50
70 311.4 50 273.2 87.7 50 257.7 82.8 49 250.5 80.4 50 248.7 79.9 50
74 318.4 50 281.2 88.3 50 269.6 84.7 48 261.8 82.2 50 257.9 81.0 49
78 319.7 50 284.9 89.1 49 271.7 85.0 48 267.2 83.6 50 261.9 81.9 48
82 321.9 49 289.6 90.0 49 275.0 85.4 48 272.5 84.7 49 264.2 82.1 48
86 330.2 46 290.2 87.9 46 279.5 84.6 45 276.5 83.7 49 268.1 81.2 48
90 335.4 43 298.5 89.0 45 282.5 84.2 45 280.8 83.7 48 275.2 82.1 48
94 337.9 39 299.0 88.5 43 280.5 83.0 43 274.1 81.1 44 271.1 80.2 48
98 345.4 33 306.0 88.6 42 295.5 85.6 40 287.6 83.3 43 276.8 80.1 48
102 342.5 28 305.0 89.1 41 290.2 84.7 38 284.4 83.0 40 271.9 79.4 46
TERM. SAC. 23 40 35 37 40
===================================================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.