TDMS Study 88120-04 Pathology Tables
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: Battelle Columbus P,P'-DICHLORODIPHENYL SULFONE DATE: 09/24/99
EXPERIMENT: 88120 TEST: 04 TIME: 08:17:36
CAGES FROM 0000 TO LAST CAGE PAGE: 1
TEST TYPE: CHRONIC ROUTE: DOSED FEED NTP: C88120B
CONT: NO1-ES-55388 CAS: 80-07-9
------------------------------------------------------------------------------------------------------------------------------------
REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: BATTELLE COLUMBUS LABORATORY P,P'-DICHLORODIPHENYL SULFONE DATE: 09/24/99
EXPERIMENT: 88120 TEST: 04 TIME: 8:27:33
TEST TYPE: TWO YEAR ROUTE: DOSED FEED NTP: 88120B
CONT: NO1-ES-55388 CAS: 80-07-9
MEAN BODY WEIGHTS AND SURVIVAL OF MALE MICE IN THE
TWO YEAR DOSED FEED STUDY OF P,P'-DICHLORODIPHENYL SULFONE
==========================================================================================================
WEEK 0 PPM 30 PPM 100 PPM 300 PPM
---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
=========================================================================================================
B 20.4 50 20.4 100.0 50 20.4 100.0 50 20.4 100.0 50
1 20.4 50 20.4 100.0 50 20.4 100.0 50 20.4 100.0 50
2 20.8 50 20.6 99.0 50 20.7 99.5 50 20.4 98.1 50
6 26.2 49 25.3 96.6 50 25.6 97.7 49 24.4 93.1 49
10 28.4 49 28.3 99.6 49 28.2 99.3 49 27.1 95.4 49
14 32.1 49 32.1 100.0 49 32.1 100.0 49 30.2 94.1 49
18 35.6 49 34.6 97.2 49 34.6 97.2 49 33.0 92.7 49
22 39.0 49 37.3 95.6 49 37.0 94.9 49 35.5 91.0 49
26 41.2 49 39.1 94.9 49 38.9 94.4 49 36.3 88.1 49
30 42.3 49 39.5 93.4 49 38.9 92.0 49 37.0 87.5 49
34 43.7 49 41.8 95.7 49 40.9 93.6 49 39.2 89.7 49
38 44.5 49 42.4 95.3 49 42.1 94.6 49 39.7 89.2 49
42 44.7 49 42.4 94.9 49 42.2 94.4 49 40.0 89.5 49
46 46.0 49 43.4 94.3 49 42.2 91.7 49 41.1 89.3 49
50 45.8 49 43.5 95.0 49 42.8 93.4 49 40.9 89.3 49
54 46.2 49 44.2 95.7 49 43.4 93.9 49 41.2 89.2 48
58 46.9 49 45.1 96.2 49 44.2 94.2 49 42.1 89.8 47
62 46.3 49 45.0 97.2 49 44.5 96.1 47 41.9 90.5 46
66 46.0 49 45.0 97.8 49 44.2 96.1 47 41.6 90.4 46
70 45.5 49 45.2 99.3 49 44.4 97.6 47 41.4 91.0 46
74 46.2 49 45.9 99.4 49 44.4 96.1 47 42.5 92.0 45
78 45.3 49 45.3 100.0 49 43.8 96.7 46 42.3 93.4 45
82 44.0 48 44.0 100.0 48 42.7 97.0 46 41.4 94.1 45
86 42.8 48 43.1 100.7 48 42.2 98.6 46 40.4 94.4 45
90 40.9 47 41.4 101.2 48 41.2 100.7 46 38.7 94.6 44
94 37.9 45 39.5 104.2 47 39.4 104.0 45 36.5 96.3 44
98 37.4 43 38.0 101.6 47 37.7 100.8 45 35.2 94.1 44
102 36.5 41 37.4 102.5 47 36.5 100.0 44 34.6 94.8 43
TERM. SAC. 40 45 44 42
==========================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.
MEAN BODY WEIGHTS AND SURVIVAL OF FEMALE MICE IN THE
TWO YEAR DOSED FEED STUDY OF P,P'-DICHLORODIPHENYL SULFONE
==========================================================================================================
WEEK 0 PPM 30 PPM 100 PPM 300 PPM
---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
=========================================================================================================
B 17.2 50 17.5 101.7 50 17.3 100.6 50 17.2 100.0 50
1 17.2 50 17.5 101.7 50 17.3 100.6 50 17.2 100.0 50
2 17.2 50 17.3 100.6 50 17.3 100.6 50 16.9 98.3 50
6 21.2 50 21.5 101.4 50 21.1 99.5 50 20.3 95.8 50
10 23.0 50 23.5 102.2 50 23.6 102.6 50 22.5 97.8 50
14 25.5 50 26.8 105.1 50 26.7 104.7 50 24.3 95.3 50
18 29.6 50 30.4 102.7 50 29.8 100.7 50 27.0 91.2 50
22 32.0 50 34.3 107.2 50 32.7 102.2 50 29.5 92.2 50
26 36.0 50 36.9 102.5 50 34.6 96.1 50 31.5 87.5 50
30 37.1 50 38.6 104.0 50 36.1 97.3 50 32.5 87.6 50
34 39.0 50 40.1 102.8 50 38.3 98.2 50 35.3 90.5 50
38 40.3 50 41.1 102.0 50 39.5 98.0 50 35.5 88.1 50
42 42.1 50 42.8 101.7 50 41.5 98.6 50 37.6 89.3 50
46 42.4 50 43.4 102.4 50 40.5 95.5 50 37.6 88.7 50
50 43.0 50 43.7 101.6 50 41.2 95.8 50 38.2 88.8 50
54 43.4 50 44.9 103.5 50 42.5 97.9 50 38.7 89.2 50
58 44.7 50 46.4 103.8 50 44.1 98.7 50 40.6 90.8 50
62 45.1 50 47.0 104.2 50 44.4 98.4 50 39.9 88.5 50
66 44.9 50 46.8 104.2 50 43.8 97.6 50 39.3 87.5 50
70 44.8 50 47.0 104.9 50 43.7 97.5 50 40.1 89.5 50
74 46.5 49 48.6 104.5 48 45.8 98.5 50 42.0 90.3 50
78 46.0 49 47.9 104.1 48 45.2 98.3 50 41.2 89.6 50
82 45.7 49 48.7 106.6 47 45.0 98.5 50 41.1 89.9 50
86 44.4 48 46.9 105.6 46 43.6 98.2 49 39.5 89.0 49
90 43.4 47 44.9 103.5 44 42.0 96.8 49 38.5 88.7 49
94 42.9 45 43.8 102.1 44 40.2 93.7 48 37.5 87.4 49
98 43.7 44 44.5 101.8 43 41.0 93.8 48 37.7 86.3 49
102 43.0 43 44.3 103.0 41 40.3 93.7 46 37.3 86.7 47
TERM. SAC. 42 40 43 45
==========================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.
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