https://ntp.niehs.nih.gov/go/10618

Oleic Acid Diethamolamine Condensate

NTP  EXP/TEST: 91014-04                       OLEIC ACID DIETHANOLAMINE CONDENSATE                                PAGE: 1
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 09/23/97
ROUTE: SKIN APPLICATION                                                                                           TIME: 09:26:34
                                                         EIS REPORT 37
       FACILITY:  Battelle Columbus Laboratory
       NTP C#:  C91014
       CONTRACT NUMBER:  N01-ES-15314
       CAS NUMBER:  93-83-4
       ANIMAL SUPPLIER:  TACONIC FARMS
       CAGE RANGE:  ALL
       DATE RANGE: ALL
       REASONS FOR REMOVAL:    ALL
       REMOVAL DATE RANGE:     ALL
       TREATMENT GROUPS:       INCLUDE ALL
NTP  EXP/TEST: 91014-04                       OLEIC ACID DIETHANOLAMINE CONDENSATE                                PAGE: 2
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 09/23/97
ROUTE: SKIN APPLICATION                                     EISRPT37                                              TIME: 09:26:34
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 SPECIES-STRAIN: MICE-B6C3F1                         TRT#: 2                      ROOM/AREA:    235         FIRST DOSE: 05/11/93
            SEX: FEMALE                               TRT: 0 MG/KG            PROCEDURE SET:      2
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                FIRST OCCUR'D  LAST  OCCUR'D  FREQ/
CAGE     ANIMAL  DAY    DATE    DAY    DATE  TOT OBS CLINICAL OBSERVATION
----     ------ -------------  ------------- ------- --------------------
                              THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP  EXP/TEST: 91014-04                       OLEIC ACID DIETHANOLAMINE CONDENSATE                                PAGE: 3
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 09/23/97
ROUTE: SKIN APPLICATION                                     EISRPT37                                              TIME: 09:26:34
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 SPECIES-STRAIN: MICE-B6C3F1                         TRT#: 4                      ROOM/AREA:    235         FIRST DOSE: 05/11/93
            SEX: FEMALE                               TRT: 15 MG/KG           PROCEDURE SET:      2
------------------------------------------------------------------------------------------------------------------------------------
                FIRST OCCUR'D  LAST  OCCUR'D  FREQ/
CAGE     ANIMAL  DAY    DATE    DAY    DATE  TOT OBS CLINICAL OBSERVATION
----     ------ -------------  ------------- ------- --------------------
                              THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP  EXP/TEST: 91014-04                       OLEIC ACID DIETHANOLAMINE CONDENSATE                                PAGE: 4
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 09/23/97
ROUTE: SKIN APPLICATION                                     EISRPT37                                              TIME: 09:26:34
------------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: MICE-B6C3F1                         TRT#: 6                      ROOM/AREA:    235         FIRST DOSE: 05/11/93
            SEX: FEMALE                               TRT: 30 MG/KG           PROCEDURE SET:      2
------------------------------------------------------------------------------------------------------------------------------------
                FIRST OCCUR'D  LAST  OCCUR'D  FREQ/
CAGE     ANIMAL  DAY    DATE    DAY    DATE  TOT OBS CLINICAL OBSERVATION
----     ------ -------------  ------------- ------- --------------------
307         307  638 02/07/95   638 02/07/95   1/24  Irritation Site of Applic
NTP  EXP/TEST: 91014-04                       OLEIC ACID DIETHANOLAMINE CONDENSATE                                PAGE: 5
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 09/23/97
ROUTE: SKIN APPLICATION                                     EISRPT37                                              TIME: 09:26:34
------------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: MICE-B6C3F1                         TRT#: 1                      ROOM/AREA:    235         FIRST DOSE: 05/10/93
            SEX: MALE                                 TRT: 0 MG/KG            PROCEDURE SET:      1
------------------------------------------------------------------------------------------------------------------------------------
                FIRST OCCUR'D  LAST  OCCUR'D  FREQ/
CAGE     ANIMAL  DAY    DATE    DAY    DATE  TOT OBS CLINICAL OBSERVATION
----     ------ -------------  ------------- ------- --------------------
                              THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP  EXP/TEST: 91014-04                       OLEIC ACID DIETHANOLAMINE CONDENSATE                                PAGE: 6
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 09/23/97
ROUTE: SKIN APPLICATION                                     EISRPT37                                              TIME: 09:26:34
------------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: MICE-B6C3F1                         TRT#: 3                      ROOM/AREA:    235         FIRST DOSE: 05/10/93
            SEX: MALE                                 TRT: 15 MG/KG           PROCEDURE SET:      1
------------------------------------------------------------------------------------------------------------------------------------
                FIRST OCCUR'D  LAST  OCCUR'D  FREQ/
CAGE     ANIMAL  DAY    DATE    DAY    DATE  TOT OBS CLINICAL OBSERVATION
----     ------ -------------  ------------- ------- --------------------
107         107   78 07/26/93    78 07/26/93   1/26  Irritation Site of Applic
NTP  EXP/TEST: 91014-04                       OLEIC ACID DIETHANOLAMINE CONDENSATE                                PAGE: 7
TEST TYPE: CHRONIC               DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL                    DATE: 09/23/97
ROUTE: SKIN APPLICATION                                     EISRPT37                                              TIME: 09:26:34
------------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: MICE-B6C3F1                         TRT#: 5                      ROOM/AREA:    235         FIRST DOSE: 05/10/93
            SEX: MALE                                 TRT: 30 MG/KG           PROCEDURE SET:      1
------------------------------------------------------------------------------------------------------------------------------------
                FIRST OCCUR'D  LAST  OCCUR'D  FREQ/
CAGE     ANIMAL  DAY    DATE    DAY    DATE  TOT OBS CLINICAL OBSERVATION
----     ------ -------------  ------------- ------- --------------------
116         116   78 07/26/93   106 08/23/93   2/26  Irritation Site of Applic
118         118   78 07/26/93    78 07/26/93   1/26  Irritation Site of Applic
120         120   78 07/26/93    78 07/26/93   1/23  Irritation Site of Applic
124         124  470 08/22/94   470 08/22/94   1/17  Irritation Site of Applic
127         127   78 07/26/93   106 08/23/93   2/12  Irritation Site of Applic
129         129   78 07/26/93    78 07/26/93   1/20  Irritation Site of Applic
133         133   78 07/26/93    78 07/26/93   1/3   Irritation Site of Applic
138         138  638 02/06/95   638 02/06/95   1/23  Irritation Site of Applic
140         140  106 08/23/93   106 08/23/93   1/20  Irritation Site of Applic
141         141   78 07/26/93    78 07/26/93   1/26  Irritation Site of Applic
143         143   78 07/26/93    78 07/26/93   1/26  Irritation Site of Applic
145         145   78 07/26/93    78 07/26/93   1/26  Irritation Site of Applic
147         147   78 07/26/93   582 12/12/94   3/21  Irritation Site of Applic
149         149   78 07/26/93    78 07/26/93   1/26  Irritation Site of Applic
150         150   78 07/26/93    78 07/26/93   1/26  Irritation Site of Applic
159         159   78 07/26/93    78 07/26/93   1/3   Irritation Site of Applic
161         161   78 07/26/93    78 07/26/93   1/15  Irritation Site of Applic
162         162   78 07/26/93    78 07/26/93   1/3   Irritation Site of Applic
163         163   78 07/26/93    78 07/26/93   1/3   Irritation Site of Applic
164         164  106 08/23/93   106 08/23/93   1/23  Irritation Site of Applic
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