https://ntp.niehs.nih.gov/go/9102

TDMS Study 92012-05 Pathology Tables

NTP  EXP/TEST: 92012-05                                2-METHYLIMIDAZOLE                                          PAGE: 1
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 02/24/03
ROUTE: DOSED FEED                                                                                                 TIME: 13:44:08
                                                         EIS REPORT 03
       FACILITY:  Southern Research Institute
       NTP C#:  92012B
       CONTRACT NUMBER:  N01-ES-85420
       CAS NUMBER:  693-98-1
       ANIMAL SUPPLIER:  TACONIC FARMS
       CAGE RANGE:  ALL
       DATE RANGE: ALL
       REASONS FOR REMOVAL:    ALL
       REMOVAL DATE RANGE:     ALL
       TREATMENT GROUPS:       INCLUDE ALL
NTP  EXP/TEST: 92012-05                                2-METHYLIMIDAZOLE                                          PAGE: 2
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 02/24/03
ROUTE: DOSED FEED                                           EISRPT03                                              TIME: 13:44:08
----------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: F 344-RATS                 SEX: FEMALE      WEEK ON DOSE: 106    FIRST DOSE: 07/15/98
----------------------------------------------------------------------------------------------------------------------------------
                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD
 0PPM               60     98.5    6.5        40    320.6   24.7                     40    221.5   21.5
 1000 PPM           60     99.2    5.9        39    308.5   23.4        96.2         39    208.0   21.9
 2500 PPM           60     98.2    6.9        28    283.1   23.3        88.3         28    184.4   21.9
 5000 PPM           60     97.7    6.5        41    227.9   24.4        71.0         41    130.3   26.1
----------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: F 344-RATS                 SEX: MALE        WEEK ON DOSE: 106    FIRST DOSE: 07/15/98
----------------------------------------------------------------------------------------------------------------------------------
                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD
 0PPM               60    114.4   11.5        34    414.7   31.0                     34    300.4   31.6
 300 PPM            60    112.7   11.3        39    416.0   23.3       100.3         39    302.6   24.2
 1000 PPM           60    113.5   10.8        35    406.7   26.3        98.0         35    292.9   21.2
 3000 PPM           60    113.2   10.5        35    375.2   35.1        90.4         35    260.5   36.2
                                               -----------------------------------
                                               ---------- END-OF-REPORT ----------
                                               -----------------------------------