https://ntp.niehs.nih.gov/go/3161

TDMS Study 92012-06 Pathology Tables

NTP  EXP/TEST: 92012-06                                2-METHYLIMIDAZOLE                                          PAGE: 1
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 02/24/03
ROUTE: DOSED FEED                                                                                                 TIME: 13:58:03
                                                         EIS REPORT 03
       FACILITY:  Southern Research Institute
       NTP C#:  92012B
       CONTRACT NUMBER:  N01-ES-85420
       CAS NUMBER:  693-98-1
       ANIMAL SUPPLIER:  TACONIC FARMS
       CAGE RANGE:  ALL
       DATE RANGE: ALL
       REASONS FOR REMOVAL:    ALL
       REMOVAL DATE RANGE:     ALL
       TREATMENT GROUPS:       INCLUDE ALL
NTP  EXP/TEST: 92012-06                                2-METHYLIMIDAZOLE                                          PAGE: 2
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 02/24/03
ROUTE: DOSED FEED                                           EISRPT03                                              TIME: 13:58:03
----------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: B6C3F1-MICE                SEX: FEMALE      WEEK ON DOSE: 105    FIRST DOSE: 07/29/98
----------------------------------------------------------------------------------------------------------------------------------
                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD
 0PPM               60     17.4    1.2        46     37.8    6.3                     46     20.5    6.3
 625 PPM            60     17.3    1.1        42     38.4    5.1       101.5         42     21.1    5.2
 1250 PPM           60     17.3    1.2        42     38.1    5.7       100.7         42     20.7    5.5
 2500 PPM           60     17.7    1.0        45     33.6    4.2        88.8         45     15.9    3.9
----------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: B6C3F1-MICE                SEX: MALE        WEEK ON DOSE: 105    FIRST DOSE: 07/29/98
----------------------------------------------------------------------------------------------------------------------------------
                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD
 0PPM               60     21.0    1.7        43     42.5    8.0                     43     21.5    7.7
 625 PPM            60     21.0    1.6        46     42.2    8.4        99.2         46     21.3    8.5
 1250 PPM           60     21.1    1.5        36     40.8    8.7        96.0         36     19.5    8.5
 2500 PPM           60     20.8    1.7        40     37.3    6.0        87.7         40     16.1    6.0
                                               -----------------------------------
                                               ---------- END-OF-REPORT ----------
                                               -----------------------------------