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TDMS Study 96007-04 Pathology Tables

NTP  EXP/TEST: 96007-04               TOXIC EQUIVALENCY FACTOR EVALUATION (DIOXIN MIXTURE)                        PAGE: 1
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 04/22/03
ROUTE: GAVAGE                                                                                                     TIME: 11:03:09

                                                         EIS REPORT 03


       FACILITY:  Battelle Columbus Laboratory

       NTP C#:  96007B

       CONTRACT NUMBER:  NO1-ES-75411

       CAS NUMBER:  TEFDIOXINMIX

       ANIMAL SUPPLIER:  HARLAN SPRAGUE-DAWLEY

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 96007-04               TOXIC EQUIVALENCY FACTOR EVALUATION (DIOXIN MIXTURE)                        PAGE: 2
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 04/22/03
ROUTE: GAVAGE                                               EISRPT03                                              TIME: 11:03:09
----------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: SD-RATS                    SEX: FEMALE      WEEK ON DOSE: 105    FIRST DOSE: 06/16/98
----------------------------------------------------------------------------------------------------------------------------------
                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 TERT.MIXCONTROL    98    178.9    8.4        16    374.8   38.5                     16    202.7   37.1

 TERT.MIXTEQ=10     98    178.9    7.4        23    362.2   45.7        96.6         23    181.1   45.1

 TERT.MIXTEQ=22     98    178.4    7.8        24    349.7   44.4        93.3         24    173.8   44.4

 TERT.MIXTEQ=46     98    180.1    8.7        23    338.5   41.1        90.3         23    159.1   37.6

 TERT.MIXTEQ=100    98    179.2    8.1         8    298.3   42.8        79.5          8    118.5   43.7

                                               -----------------------------------
                                               ---------- END-OF-REPORT ----------
                                               -----------------------------------