TDMS Study 96010-03 Pathology Tables
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: Southern Research Inst WATER DISINFECTION BYPRODUCTS (SODIUM CHLORATE) DATE: 05/27/03
EXPERIMENT: 96010 TEST: 03 TIME: 13:17:40
CAGES FROM 0000 TO LAST CAGE PAGE: 1
TEST TYPE: CHRONIC ROUTE: DOSED WATER NTP: C96010A
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FINAL#1/RATS
REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: SOUTHERN RESEARCH INSTITUTE WATER DISINFECTION BYPRODUCTS (SODIUM CHLORATE) DATE: 05/27/03
EXPERIMENT: 96010 TEST: 03 TIME: 13:28:11
SPECIES: RATS, FISCHER 344
TEST TYPE: TWO YEAR ROUTE: DOSED WATER NTP: 96010A
CONT: N01-ES-85420 CAS: 7775-09-9
MEAN BODY WEIGHTS AND SURVIVAL OF MALE RATS IN THE
TWO YEAR DOSED WATER STUDY OF WATER DISINFECTION BYPRODUCTS (SODIUM CHLORATE)
==========================================================================================================
WEEK 0 MG/L 125 MG/L 1000MG/L 2000MG/L
---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
=========================================================================================================
B 102.1 50 103.0 100.9 50 102.9 100.8 50 102.7 100.6 50
1 102.1 50 103.0 100.9 50 102.9 100.8 50 102.7 100.6 50
4 187.3 50 187.1 99.9 50 184.9 98.7 50 185.9 99.3 50
8 261.0 50 262.5 100.6 50 265.5 101.7 50 270.1 103.5 50
12 312.2 50 315.4 101.0 50 319.3 102.3 50 322.2 103.2 50
16 347.6 50 351.1 101.0 50 356.8 102.6 50 358.0 103.0 50
20 373.1 50 374.3 100.3 50 378.9 101.6 50 381.7 102.3 50
24 392.5 50 395.7 100.8 50 401.8 102.4 50 402.7 102.6 50
28 420.0 50 422.9 100.7 50 428.6 102.0 50 427.6 101.8 50
32 436.5 50 439.1 100.6 50 444.8 101.9 49 445.6 102.1 50
36 441.8 50 444.6 100.6 50 451.9 102.3 49 450.7 102.0 50
40 459.4 50 461.2 100.4 50 466.4 101.5 49 468.0 101.9 50
44 467.1 50 473.7 101.4 50 476.5 102.0 49 478.3 102.4 50
48 474.7 50 478.8 100.9 50 481.7 101.5 49 485.6 102.3 50
52 487.3 50 490.9 100.7 50 493.2 101.2 49 494.0 101.4 50
56 489.2 49 493.2 100.8 50 497.0 101.6 49 498.1 101.8 50
60 494.9 49 499.3 100.9 50 501.1 101.3 49 501.3 101.3 50
64 498.9 48 503.1 100.8 50 505.1 101.2 49 504.6 101.1 50
68 500.4 47 502.7 100.5 50 504.2 100.8 49 504.9 100.9 48
72 496.7 47 501.8 101.0 50 505.8 101.8 48 504.1 101.5 47
76 508.1 45 505.8 99.5 50 508.3 100.0 48 509.4 100.3 47
80 507.8 44 505.8 99.6 49 507.3 99.9 48 507.5 99.9 46
84 512.2 43 507.5 99.1 45 512.7 100.1 45 509.6 99.5 45
88 508.9 43 501.3 98.5 44 516.0 101.4 43 509.5 100.1 44
92 514.1 39* 501.1 97.5 41 513.6 99.9 42 507.8 98.8 43
96 507.3 40 499.9 98.5 38 504.6 99.5 40 497.5 98.1 40
100 496.5 40 486.1 97.9 35 503.5 101.4 37 488.4 98.4 36
104 489.6 36 496.5 101.4 28 499.7 102.1 31 495.6 101.2 28
TERM. SAC. 36 27 31 28
==========================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.
MEAN BODY WEIGHTS AND SURVIVAL OF FEMALE RATS IN THE
TWO YEAR DOSED WATER STUDY OF WATER DISINFECTION BYPRODUCTS (SODIUM CHLORATE)
==========================================================================================================
WEEK 0 MG/L 125 MG/L 1000MG/L 2000MG/L
---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
=========================================================================================================
B 91.3 50 90.7 99.3 50 91.0 99.7 50 89.1 97.6 50
1 91.3 50 90.7 99.3 50 91.0 99.7 50 89.1 97.6 50
4 139.6 50 140.9 100.9 50 139.7 100.1 50 137.5 98.5 50
8 168.7 50 171.1 101.4 50 169.6 100.5 50 169.1 100.2 50
12 185.5 50 186.7 100.6 50 187.7 101.2 50 185.5 100.0 50
16 197.0 50 199.7 101.4 50 199.3 101.2 50 196.3 99.6 50
20 204.9 50 207.7 101.4 50 207.7 101.4 50 204.4 99.8 50
24 212.9 50 215.4 101.2 50 215.7 101.3 50 212.3 99.7 50
28 227.8 50 230.4 101.1 50 232.2 101.9 50 226.2 99.3 50
32 231.9 50 235.6 101.6 50 236.9 102.2 50 231.2 99.7 50
36 235.4 50 238.5 101.3 50 240.0 102.0 50 235.8 100.2 50
40 246.0 50 250.4 101.8 50 248.3 100.9 50 243.8 99.1 50
44 258.9 50 267.6 103.4 50 264.7 102.2 50 258.9 100.0 50
48 260.4 50 265.7 102.0 50 262.8 100.9 50 259.4 99.6 50
52 271.1 50 277.1 102.2 50 276.1 101.8 50 266.8 98.4 50
56 278.3 50 282.5 101.5 49 283.6 101.9 50 276.2 99.2 50
60 285.4 50 287.1 100.6 49 292.6 102.5 49 282.7 99.1 50
64 294.2 49 300.5 102.1 47 303.6 103.2 49 290.9 98.9 50
68 303.9 48 309.8 101.9 47 308.9 101.6 49 298.3 98.2 50
72 308.2 48 313.2 101.6 47 315.6 102.4 49 305.1 99.0 49
76 322.4 47 324.6 100.7 46 327.8 101.7 47 317.3 98.4 49
80 327.1 46 330.6 101.1 45 332.2 101.6 46 323.4 98.9 48
84 331.3 45 337.1 101.8 44 336.8 101.7 45 329.5 99.5 48
88 336.6 43 338.3 100.5 44 340.9 101.3 43 330.6 98.2 48
92 340.1 42 342.4 100.7 40 345.2 101.5 38 338.5 99.5 46
96 340.0 40 342.5 100.7 38 352.0 103.5 37 332.3 97.7 45
100 341.7 40 350.3 102.5 38 351.3 102.8 37 336.7 98.5 42
104 338.7 38 351.0 103.6 37 358.7 105.9 33 341.1 100.7 41
TERM. SAC. 37 36 33 41
==========================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.
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