https://ntp.niehs.nih.gov/go/6817

TDMS Study 97006-01 Pathology Tables

NTP  EXP/TEST: 97006-01                              METHYL ISOBUTYL KETONE                                       PAGE: 1
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 05/11/04
ROUTE: RESPIRATORY EXPOSURE WHOLE BODY                                                                            TIME: 08:44:53
                                                         EIS REPORT 03
       FACILITY:  Battelle Northwest
       NTP C#:  C97006
       CONTRACT NUMBER:  N01-ES-05452
       CAS NUMBER:  108-10-1
       ANIMAL SUPPLIER:  TACONIC FARMS
       CAGE RANGE:  ALL
       DATE RANGE: ALL
       REASONS FOR REMOVAL:    ALL
       REMOVAL DATE RANGE:     ALL
       TREATMENT GROUPS:       INCLUDE ALL
NTP  EXP/TEST: 97006-01                              METHYL ISOBUTYL KETONE                                       PAGE: 2
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 05/11/04
ROUTE: RESPIRATORY EXPOSURE WHOLE BODY                      EISRPT03                                              TIME: 08:44:53
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 SPECIES-STRAIN: F 344-RATS                 SEX: FEMALE      WEEK ON DOSE: 105    FIRST DOSE: 05/25/00
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD
 CONTROL            50     93.5    5.9        35    362.9   32.9                     35    268.8   34.2
 450 PPM            50     92.2    5.8        33    361.3   35.2        99.5         33    268.7   33.8
 900 PPM            50     92.1    5.9        26    378.0   46.0       104.1         26    286.3   44.9
 1800 PPM           50     93.3    6.4        32    362.6   24.1        99.9         32    268.6   23.3
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 SPECIES-STRAIN: F 344-RATS                 SEX: MALE        WEEK ON DOSE: 105    FIRST DOSE: 05/25/00
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD
 CONTROL            50    104.1    9.7        32    521.0   47.5                     32    418.4   51.0
 450 PPM            50    103.5    9.1        28    511.9   71.1        98.2         28    409.3   71.3
 900 PPM            50    102.9    9.3        25    494.7   60.1        94.9         25    393.2   61.0
 1800 PPM           50    102.0    8.6        19    489.9   44.8        94.0         19    387.1   42.6
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