TDMS Study 97013-15 Pathology Tables
NTP EXP/TEST: 97013-15 WATER DISINFECTION MODEL (DICHLOROACETIC ACID) PAGE: 1
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 01/27/05
ROUTE: SKIN APPLICATION TIME: 09:17:27
EIS REPORT 37
FACILITY: Battelle Columbus Laboratory
NTP C#: 97013D
CONTRACT NUMBER: N01-ES-65406
CAS NUMBER: 79-43-6
ANIMAL SUPPLIER: TACONIC FARMS
CAGE RANGE: ALL
DATE RANGE: ALL
REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP EXP/TEST: 97013-15 WATER DISINFECTION MODEL (DICHLOROACETIC ACID) PAGE: 2
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 01/27/05
ROUTE: SKIN APPLICATION EISRPT37 TIME: 09:17:27
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SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 2 ROOM/AREA: 207 FIRST DOSE: 02/17/00
SEX: FEMALE TRT: 0 MG/KG PROCEDURE SET: 2
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 97013-15 WATER DISINFECTION MODEL (DICHLOROACETIC ACID) PAGE: 3
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 01/27/05
ROUTE: SKIN APPLICATION EISRPT37 TIME: 09:17:27
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 4 ROOM/AREA: 207 FIRST DOSE: 02/17/00
SEX: FEMALE TRT: 31.25 MG/KG PROCEDURE SET: 2
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 97013-15 WATER DISINFECTION MODEL (DICHLOROACETIC ACID) PAGE: 4
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 01/27/05
ROUTE: SKIN APPLICATION EISRPT37 TIME: 09:17:27
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 6 ROOM/AREA: 207 FIRST DOSE: 02/17/00
SEX: FEMALE TRT: 125MG/KG PROCEDURE SET: 2
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 97013-15 WATER DISINFECTION MODEL (DICHLOROACETIC ACID) PAGE: 5
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 01/27/05
ROUTE: SKIN APPLICATION EISRPT37 TIME: 09:17:27
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 10 ROOM/AREA: 207 FIRST DOSE: 02/17/00
SEX: FEMALE TRT: TPA PROCEDURE SET: 2
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
536 536 71 04/27/00 71 04/27/00 1/12 Papilloma Site Of Application Small 13
78 05/04/00 78 05/04/00 1/12 Papilloma Site Of Application Small 20
REMOVED ** CID 536 ** REASON - Other
84 05/10/00 Papilloma Site Of Application Small 20
537 537 57 04/13/00 57 04/13/00 1/10 Papilloma Site Of Application Small 19
64 04/20/00 64 04/20/00 1/10 Papilloma Site Of Application Small 20
REMOVED ** CID 537 ** REASON - Other
68 04/24/00 Papilloma Site Of Application Small 20
538 538 57 04/13/00 57 04/13/00 1/9 Papilloma Site Of Application Small 20
REMOVED ** CID 538 ** REASON - MSAC
58 04/14/00 Papilloma Site Of Application Small 20
539 539 57 04/13/00 57 04/13/00 1/10 Papilloma Site Of Application Small 18
64 04/20/00 64 04/20/00 1/10 Papilloma Site Of Application Small 20
REMOVED ** CID 539 ** REASON - Other
68 04/24/00 Papilloma Site Of Application Small 20
540 540 78 05/04/00 78 05/04/00 1/13 Papilloma Site Of Application Small 10
85 05/11/00 85 05/11/00 1/13 Papilloma Site Of Application Small 20
71 04/27/00 71 04/27/00 1/13 Papilloma Site Of Application Small 6
REMOVED ** CID 540 ** REASON - Other
90 05/16/00 Papilloma Site Of Application Small 20
541 541 71 04/27/00 71 04/27/00 1/11 Papilloma Site Of Application Small 20
64 04/20/00 64 04/20/00 1/11 Papilloma Site Of Application Small 9
REMOVED ** CID 541 ** REASON - Other
75 05/01/00 Papilloma Site Of Application Small 20
542 542 71 04/27/00 71 04/27/00 1/11 Papilloma Site Of Application Small 20
REMOVED ** CID 542 ** REASON - Other
75 05/01/00 Papilloma Site Of Application Small 20
NTP EXP/TEST: 97013-15 WATER DISINFECTION MODEL (DICHLOROACETIC ACID) PAGE: 6
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 01/27/05
ROUTE: SKIN APPLICATION EISRPT37 TIME: 09:17:27
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 10 ROOM/AREA: 207 FIRST DOSE: 02/17/00
SEX: FEMALE TRT: TPA PROCEDURE SET: 2
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
543 543 64 04/20/00 64 04/20/00 1/10 Papilloma Site Of Application Small 20
REMOVED ** CID 543 ** REASON - Other
68 04/24/00 Papilloma Site Of Application Small 20
544 544 64 04/20/00 64 04/20/00 1/15 Papilloma Site Of Application Small 1
92 05/18/00 92 05/18/00 1/15 Papilloma Site Of Application Small 16
71 04/27/00 71 04/27/00 1/15 Papilloma Site Of Application Small 2
99 05/25/00 99 05/25/00 1/15 Papilloma Site Of Application Small 20
78 05/04/00 78 05/04/00 1/15 Papilloma Site Of Application Small 3
85 05/11/00 85 05/11/00 1/15 Papilloma Site Of Application Small 4
REMOVED ** CID 544 ** REASON - Other
100 05/26/00 Papilloma Site Of Application Small 20
545 545 71 04/27/00 71 04/27/00 1/13 Papilloma Site Of Application Small 14
78 05/04/00 78 05/04/00 1/13 Papilloma Site Of Application Small 18
85 05/11/00 85 05/11/00 1/13 Papilloma Site Of Application Small 20
64 04/20/00 64 04/20/00 1/13 Papilloma Site Of Application Small 7
REMOVED ** CID 545 ** REASON - Other
90 05/16/00 Papilloma Site Of Application Small 20
546 546 92 05/18/00 92 05/18/00 1/15 Papilloma Site Of Application Small 11
85 05/11/00 85 05/11/00 1/15 Papilloma Site Of Application Small 13
78 05/04/00 78 05/04/00 1/15 Papilloma Site Of Application Small 14
99 05/25/00 99 05/25/00 1/15 Papilloma Site Of Application Small 20
71 04/27/00 71 04/27/00 1/15 Papilloma Site Of Application Small 8
REMOVED ** CID 546 ** REASON - Other
100 05/26/00 Papilloma Site Of Application Small 20
547 547 99 05/25/00 106 06/01/00 2/18 Papilloma Site Of Application Small 11
113 06/08/00 113 06/08/00 1/18 Papilloma Site Of Application Small 14
71 04/27/00 71 04/27/00 1/18 Papilloma Site Of Application Small 2
120 06/15/00 120 06/15/00 1/18 Papilloma Site Of Application Small 20
78 05/04/00 85 05/11/00 2/18 Papilloma Site Of Application Small 5
92 05/18/00 92 05/18/00 1/18 Papilloma Site Of Application Small 8
REMOVED ** CID 547 ** REASON - Other
124 06/19/00 Papilloma Site Of Application Small 20
548 548 71 04/27/00 71 04/27/00 1/11 Papilloma Site Of Application Small 20
NTP EXP/TEST: 97013-15 WATER DISINFECTION MODEL (DICHLOROACETIC ACID) PAGE: 7
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 01/27/05
ROUTE: SKIN APPLICATION EISRPT37 TIME: 09:17:27
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 10 ROOM/AREA: 207 FIRST DOSE: 02/17/00
SEX: FEMALE TRT: TPA PROCEDURE SET: 2
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
REMOVED ** CID 548 ** REASON - Other
548 548 75 05/01/00 Papilloma Site Of Application Small 20
549 549 71 04/27/00 71 04/27/00 1/11 Papilloma Site Of Application Small 20
REMOVED ** CID 549 ** REASON - Other
75 05/01/00 Papilloma Site Of Application Small 20
550 550 78 05/04/00 85 05/11/00 2/15 Papilloma Site Of Application Small 13
92 05/18/00 92 05/18/00 1/15 Papilloma Site Of Application Small 15
99 05/25/00 99 05/25/00 1/15 Papilloma Site Of Application Small 20
71 04/27/00 71 04/27/00 1/15 Papilloma Site Of Application Small 8
REMOVED ** CID 550 ** REASON - Other
100 05/26/00 Papilloma Site Of Application Small 20
NTP EXP/TEST: 97013-15 WATER DISINFECTION MODEL (DICHLOROACETIC ACID) PAGE: 8
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 01/27/05
ROUTE: SKIN APPLICATION EISRPT37 TIME: 09:17:27
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 8 ROOM/AREA: 207 FIRST DOSE: 02/17/00
SEX: FEMALE TRT: 500MG/KG PROCEDURE SET: 2
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
509 509 176 08/10/00 176 08/10/00 1/26 Papilloma Site Of Application Small 1
REMOVED ** CID 509 ** REASON - TSAC
183 08/17/00 Papilloma Site Of Application Small 1
183 08/17/00 Papilloma Torso/Ventral Small 1
513 513 113 06/08/00 155 07/20/00 7/26 Papilloma Site Of Application Small 1
REMOVED ** CID 513 ** REASON - TSAC
183 08/17/00 Unremarkable
515 515 106 06/01/00 176 08/10/00 11/26 Papilloma Site Of Application Small 1
REMOVED ** CID 515 ** REASON - TSAC
183 08/17/00 Mass Head Small 1
183 08/17/00 Papilloma Site Of Application Small 1
518 518 148 07/13/00 176 08/10/00 5/26 Papilloma Site Of Application Small 1
120 06/15/00 141 07/06/00 4/26 Papilloma Site Of Application Small 2
REMOVED ** CID 518 ** REASON - TSAC
183 08/17/00 Papilloma Site Of Application Small 1
NTP EXP/TEST: 97013-15 WATER DISINFECTION MODEL (DICHLOROACETIC ACID) PAGE: 9
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 01/27/05
ROUTE: SKIN APPLICATION EISRPT37 TIME: 09:17:27
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 1 ROOM/AREA: 207 FIRST DOSE: 02/17/00
SEX: MALE TRT: 0 MG/KG PROCEDURE SET: 1
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 97013-15 WATER DISINFECTION MODEL (DICHLOROACETIC ACID) PAGE: 10
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 01/27/05
ROUTE: SKIN APPLICATION EISRPT37 TIME: 09:17:27
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 3 ROOM/AREA: 207 FIRST DOSE: 02/17/00
SEX: MALE TRT: 31.25 MG/KG PROCEDURE SET: 1
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
429 429 120 06/15/00 148 07/13/00 5/26 Papilloma Site Of Application Small 1
REMOVED ** CID 429 ** REASON - TSAC
182 08/16/00 Unremarkable
NTP EXP/TEST: 97013-15 WATER DISINFECTION MODEL (DICHLOROACETIC ACID) PAGE: 11
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 01/27/05
ROUTE: SKIN APPLICATION EISRPT37 TIME: 09:17:27
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 5 ROOM/AREA: 207 FIRST DOSE: 02/17/00
SEX: MALE TRT: 125MG/KG PROCEDURE SET: 1
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 97013-15 WATER DISINFECTION MODEL (DICHLOROACETIC ACID) PAGE: 12
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 01/27/05
ROUTE: SKIN APPLICATION EISRPT37 TIME: 09:17:27
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 9 ROOM/AREA: 207 FIRST DOSE: 02/17/00
SEX: MALE TRT: TPA PROCEDURE SET: 1
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
521 521 78 05/04/00 78 05/04/00 1/14 Papilloma Site Of Application Medium 1
85 05/11/00 85 05/11/00 1/14 Papilloma Site Of Application Small 10
92 05/18/00 92 05/18/00 1/14 Papilloma Site Of Application Small 20
71 04/27/00 71 04/27/00 1/14 Papilloma Site Of Application Small 6
78 05/04/00 78 05/04/00 1/14 Papilloma Site Of Application Small 7
REMOVED ** CID 521 ** REASON - Other
93 05/19/00 Papilloma Site Of Application Small 20
522 522 64 04/20/00 64 04/20/00 1/11 Papilloma Site Of Application Small 18
71 04/27/00 71 04/27/00 1/11 Papilloma Site Of Application Small 20
57 04/13/00 57 04/13/00 1/11 Papilloma Site Of Application Small 8
REMOVED ** CID 522 ** REASON - Other
75 05/01/00 Papilloma Site Of Application Small 20
523 523 57 04/13/00 57 04/13/00 1/10 Papilloma Site Of Application Small 12
64 04/20/00 64 04/20/00 1/10 Papilloma Site Of Application Small 20
REMOVED ** CID 523 ** REASON - Other
68 04/24/00 Papilloma Site Of Application Small 20
524 524 106 06/01/00 106 06/01/00 1/17 Papilloma Site Of Application Small 10
64 04/20/00 71 04/27/00 2/17 Papilloma Site Of Application Small 15
85 05/11/00 85 05/11/00 1/17 Papilloma Site Of Application Small 2
113 06/08/00 113 06/08/00 1/17 Papilloma Site Of Application Small 20
78 05/04/00 78 05/04/00 1/17 Papilloma Site Of Application Small 6
99 05/25/00 99 05/25/00 1/17 Papilloma Site Of Application Small 7
92 05/18/00 92 05/18/00 1/17 Papilloma Site Of Application Small 8
REMOVED ** CID 524 ** REASON - Other
117 06/12/00 Papilloma Site Of Application Small 20
525 525 57 04/13/00 57 04/13/00 1/10 Papilloma Site Of Application Small 11
64 04/20/00 64 04/20/00 1/10 Papilloma Site Of Application Small 20
REMOVED ** CID 525 ** REASON - Other
68 04/24/00 Papilloma Site Of Application Small 20
526 526 71 04/27/00 71 04/27/00 1/11 Papilloma Site Of Application Small 20
REMOVED ** CID 526 ** REASON - Other
75 05/01/00 Papilloma Site Of Application Small 20
NTP EXP/TEST: 97013-15 WATER DISINFECTION MODEL (DICHLOROACETIC ACID) PAGE: 13
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 01/27/05
ROUTE: SKIN APPLICATION EISRPT37 TIME: 09:17:27
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 9 ROOM/AREA: 207 FIRST DOSE: 02/17/00
SEX: MALE TRT: TPA PROCEDURE SET: 1
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
527 527 85 05/11/00 85 05/11/00 1/15 Papilloma Site Of Application Small 10
92 05/18/00 92 05/18/00 1/15 Papilloma Site Of Application Small 15
99 05/25/00 99 05/25/00 1/15 Papilloma Site Of Application Small 20
78 05/04/00 78 05/04/00 1/15 Papilloma Site Of Application Small 9
REMOVED ** CID 527 ** REASON - Other
100 05/26/00 Papilloma Site Of Application Small 20
528 528 85 05/11/00 85 05/11/00 1/14 Papilloma Site Of Application Small 13
92 05/18/00 92 05/18/00 1/14 Papilloma Site Of Application Small 20
78 05/04/00 78 05/04/00 1/14 Papilloma Site Of Application Medium 3
78 05/04/00 78 05/04/00 1/14 Papilloma Site Of Application Small 7
71 04/27/00 71 04/27/00 1/14 Papilloma Site Of Application Small 8
REMOVED ** CID 528 ** REASON - Other
93 05/19/00 Papilloma Site Of Application Small 20
529 529 71 04/27/00 71 04/27/00 1/13 Papilloma Site Of Application Small 17
78 05/04/00 78 05/04/00 1/13 Papilloma Site Of Application Small 18
85 05/11/00 85 05/11/00 1/13 Papilloma Site Of Application Small 20
REMOVED ** CID 529 ** REASON - Other
90 05/16/00 Papilloma Site Of Application Small 20
530 530 92 05/18/00 92 05/18/00 1/15 Papilloma Site Of Application Small 11
99 05/25/00 99 05/25/00 1/15 Papilloma Site Of Application Small 20
78 05/04/00 85 05/11/00 2/15 Papilloma Site Of Application Small 6
REMOVED ** CID 530 ** REASON - Other
100 05/26/00 Papilloma Site Of Application Small 20
531 531 64 04/20/00 64 04/20/00 1/13 Papilloma Site Of Application Small 10
71 04/27/00 71 04/27/00 1/13 Papilloma Site Of Application Small 11
85 05/11/00 85 05/11/00 1/13 Papilloma Site Of Application Small 20
78 05/04/00 78 05/04/00 1/13 Papilloma Site Of Application Small 7
78 05/04/00 78 05/04/00 1/13 Papilloma Site Of Application Medium 9
REMOVED ** CID 531 ** REASON - Other
90 05/16/00 Papilloma Site Of Application Small 20
533 533 78 05/04/00 85 05/11/00 2/15 Papilloma Site Of Application Small 15
NTP EXP/TEST: 97013-15 WATER DISINFECTION MODEL (DICHLOROACETIC ACID) PAGE: 14
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 01/27/05
ROUTE: SKIN APPLICATION EISRPT37 TIME: 09:17:27
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 9 ROOM/AREA: 207 FIRST DOSE: 02/17/00
SEX: MALE TRT: TPA PROCEDURE SET: 1
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
- CONTINUATION OF PREVIOUS ANIMAL DATA -
533 533 92 05/18/00 92 05/18/00 1/15 Papilloma Site Of Application Small 16
99 05/25/00 99 05/25/00 1/15 Papilloma Site Of Application Small 20
71 04/27/00 71 04/27/00 1/15 Papilloma Site Of Application Small 6
REMOVED ** CID 533 ** REASON - Other
100 05/26/00 Papilloma Site Of Application Small 20
534 534 85 05/11/00 85 05/11/00 1/15 Papilloma Site Of Application Small 14
92 05/18/00 92 05/18/00 1/15 Papilloma Site Of Application Small 18
99 05/25/00 99 05/25/00 1/15 Papilloma Site Of Application Small 20
78 05/04/00 78 05/04/00 1/15 Papilloma Site Of Application Small 6
REMOVED ** CID 534 ** REASON - Other
100 05/26/00 Papilloma Site Of Application Small 20
535 535 64 04/20/00 64 04/20/00 1/12 Papilloma Site Of Application Small 11
71 04/27/00 71 04/27/00 1/12 Papilloma Site Of Application Small 13
78 05/04/00 78 05/04/00 1/12 Papilloma Site Of Application Small 20
57 04/13/00 57 04/13/00 1/12 Papilloma Site Of Application Small 6
REMOVED ** CID 535 ** REASON - Other
84 05/10/00 Papilloma Site Of Application Small 20
NTP EXP/TEST: 97013-15 WATER DISINFECTION MODEL (DICHLOROACETIC ACID) PAGE: 15
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 01/27/05
ROUTE: SKIN APPLICATION EISRPT37 TIME: 09:17:27
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 7 ROOM/AREA: 207 FIRST DOSE: 02/17/00
SEX: MALE TRT: 500MG/KG PROCEDURE SET: 1
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
451 451 106 06/01/00 120 06/15/00 3/26 Papilloma Site Of Application Small 1
REMOVED ** CID 451 ** REASON - TSAC
182 08/16/00 Mass Head Small 3
456 456 169 08/03/00 176 08/10/00 2/26 Papilloma Site Of Application Small 1
REMOVED ** CID 456 ** REASON - TSAC
182 08/16/00 Papilloma Site Of Application Small 1
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