TDMS Study 97013-92 Pathology Tables
NTP EXP/TEST: 97013-92 WATER DISINFECTION MODEL (SODIUM BROMATE) PAGE: 1
TEST TYPE: 26-39 WEEKS DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 12/08/03
ROUTE: SKIN APPLICATION TIME: 14:18:35
EIS REPORT 37
FACILITY: Battelle Columbus Laboratory
NTP C#: 97013B
CONTRACT NUMBER: N01-ES-65406
CAS NUMBER: 7789-38-0
ANIMAL SUPPLIER: TACONIC FARMS
CAGE RANGE: ALL
DATE RANGE: ALL
REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP EXP/TEST: 97013-92 WATER DISINFECTION MODEL (SODIUM BROMATE) PAGE: 2
TEST TYPE: 26-39 WEEKS DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 12/08/03
ROUTE: SKIN APPLICATION EISRPT37 TIME: 14:18:35
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SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 2 ROOM/AREA: 218 FIRST DOSE: 10/29/99
SEX: FEMALE TRT: 0 MG/KG PROCEDURE SET: 2
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 97013-92 WATER DISINFECTION MODEL (SODIUM BROMATE) PAGE: 3
TEST TYPE: 26-39 WEEKS DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 12/08/03
ROUTE: SKIN APPLICATION EISRPT37 TIME: 14:18:35
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 4 ROOM/AREA: 218 FIRST DOSE: 10/29/99
SEX: FEMALE TRT: 64 MG/KG PROCEDURE SET: 2
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 97013-92 WATER DISINFECTION MODEL (SODIUM BROMATE) PAGE: 4
TEST TYPE: 26-39 WEEKS DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 12/08/03
ROUTE: SKIN APPLICATION EISRPT37 TIME: 14:18:35
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 6 ROOM/AREA: 218 FIRST DOSE: 10/29/99
SEX: FEMALE TRT: 128 MG/KG PROCEDURE SET: 2
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
1263 1263 155 03/31/00 176 04/21/00 4/39 Papilloma Site Of Application Small 1
REMOVED ** CID 1263 ** REASON - TSAC
272 07/26/00 Mass Appendage Small 1
272 07/26/00 Papilloma Torso/Ventral Small 3
NTP EXP/TEST: 97013-92 WATER DISINFECTION MODEL (SODIUM BROMATE) PAGE: 5
TEST TYPE: 26-39 WEEKS DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 12/08/03
ROUTE: SKIN APPLICATION EISRPT37 TIME: 14:18:35
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 8 ROOM/AREA: 218 FIRST DOSE: 10/29/99
SEX: FEMALE TRT: 256 MG/KG PROCEDURE SET: 2
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
1276 1276 246 06/30/00 253 07/07/00 2/39 Papilloma Site Of Application Small 1
REMOVED ** CID 1276 ** REASON - TSAC
272 07/26/00 Papilloma Torso/Ventral Small 2
1280 1280 253 07/07/00 267 07/21/00 3/39 Papilloma Site Of Application Small 1
REMOVED ** CID 1280 ** REASON - TSAC
272 07/26/00 Papilloma Site Of Application Small 1
NTP EXP/TEST: 97013-92 WATER DISINFECTION MODEL (SODIUM BROMATE) PAGE: 6
TEST TYPE: 26-39 WEEKS DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 12/08/03
ROUTE: SKIN APPLICATION EISRPT37 TIME: 14:18:35
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 1 ROOM/AREA: 218 FIRST DOSE: 10/29/99
SEX: MALE TRT: 0 MG/KG PROCEDURE SET: 1
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
1202 1202 176 04/21/00 267 07/21/00 14/39 Papilloma Site Of Application Small 1
REMOVED ** CID 1202 ** REASON - TSAC
272 07/26/00 Mass Head Small 1
272 07/26/00 Papilloma Site Of Application Small 1
NTP EXP/TEST: 97013-92 WATER DISINFECTION MODEL (SODIUM BROMATE) PAGE: 7
TEST TYPE: 26-39 WEEKS DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 12/08/03
ROUTE: SKIN APPLICATION EISRPT37 TIME: 14:18:35
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 3 ROOM/AREA: 218 FIRST DOSE: 10/29/99
SEX: MALE TRT: 64 MG/KG PROCEDURE SET: 1
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 97013-92 WATER DISINFECTION MODEL (SODIUM BROMATE) PAGE: 8
TEST TYPE: 26-39 WEEKS DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 12/08/03
ROUTE: SKIN APPLICATION EISRPT37 TIME: 14:18:35
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 5 ROOM/AREA: 218 FIRST DOSE: 10/29/99
SEX: MALE TRT: 128 MG/KG PROCEDURE SET: 1
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
1223 1223 162 04/07/00 169 04/14/00 2/39 Papilloma Site Of Application Small 1
REMOVED ** CID 1223 ** REASON - TSAC
272 07/26/00 Unremarkable
1228 1228 232 06/16/00 267 07/21/00 6/39 Papilloma Site Of Application Small 1
REMOVED ** CID 1228 ** REASON - TSAC
272 07/26/00 Mass Torso/Ventral Medium 1
272 07/26/00 Papilloma Site Of Application Small 1
272 07/26/00 Papilloma Head Small 2
272 07/26/00 Papilloma Torso/Ventral Small 3
NTP EXP/TEST: 97013-92 WATER DISINFECTION MODEL (SODIUM BROMATE) PAGE: 9
TEST TYPE: 26-39 WEEKS DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 12/08/03
ROUTE: SKIN APPLICATION EISRPT37 TIME: 14:18:35
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 7 ROOM/AREA: 218 FIRST DOSE: 10/29/99
SEX: MALE TRT: 256 MG/KG PROCEDURE SET: 1
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
1233 1233 218 06/02/00 232 06/16/00 3/39 Papilloma Site Of Application Small 1
REMOVED ** CID 1233 ** REASON - TSAC
272 07/26/00 Unremarkable
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