TDMS Study 93020-07 Pathology Tables
NTP EXP/TEST: 93020-07 DIISOPROPYLCARBODIIMIDE PAGE: 1
TEST TYPE: CHRONIC DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/30/04
ROUTE: SKIN APPLICATION TIME: 11:15:09
EIS REPORT 37
FACILITY: Southern Research Institute
NTP C#: 93020D
CONTRACT NUMBER: N01-ES 05451
CAS NUMBER: 693-13-0
ANIMAL SUPPLIER: TACONIC FARMS
CAGE RANGE: ALL
DATE RANGE: ALL
REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP EXP/TEST: 93020-07 DIISOPROPYLCARBODIIMIDE PAGE: 2
TEST TYPE: CHRONIC DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/30/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 11:15:09
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SPECIES-STRAIN: RATS-F 344 TRT#: 2 ROOM/AREA: 21 FIRST DOSE: 04/24/00
SEX: FEMALE TRT: 0 MG/KG PROCEDURE SET: 2
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 93020-07 DIISOPROPYLCARBODIIMIDE PAGE: 3
TEST TYPE: CHRONIC DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/30/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 11:15:09
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SPECIES-STRAIN: RATS-F 344 TRT#: 4 ROOM/AREA: 21 FIRST DOSE: 04/24/00
SEX: FEMALE TRT: 10 MG/KG PROCEDURE SET: 2
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 93020-07 DIISOPROPYLCARBODIIMIDE PAGE: 4
TEST TYPE: CHRONIC DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/30/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 11:15:09
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SPECIES-STRAIN: RATS-F 344 TRT#: 6 ROOM/AREA: 21 FIRST DOSE: 04/24/00
SEX: FEMALE TRT: 20 MG/KG PROCEDURE SET: 2
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 93020-07 DIISOPROPYLCARBODIIMIDE PAGE: 5
TEST TYPE: CHRONIC DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/30/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 11:15:09
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: RATS-F 344 TRT#: 8 ROOM/AREA: 21 FIRST DOSE: 04/24/00
SEX: FEMALE TRT: 40 MG/KG PROCEDURE SET: 2
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 93020-07 DIISOPROPYLCARBODIIMIDE PAGE: 6
TEST TYPE: CHRONIC DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/30/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 11:15:09
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: RATS-F 344 TRT#: 1 ROOM/AREA: 21 FIRST DOSE: 04/24/00
SEX: MALE TRT: 0 MG/KG PROCEDURE SET: 1
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 93020-07 DIISOPROPYLCARBODIIMIDE PAGE: 7
TEST TYPE: CHRONIC DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/30/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 11:15:09
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: RATS-F 344 TRT#: 3 ROOM/AREA: 21 FIRST DOSE: 04/24/00
SEX: MALE TRT: 10 MG/KG PROCEDURE SET: 1
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 93020-07 DIISOPROPYLCARBODIIMIDE PAGE: 8
TEST TYPE: CHRONIC DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/30/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 11:15:09
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: RATS-F 344 TRT#: 5 ROOM/AREA: 21 FIRST DOSE: 04/24/00
SEX: MALE TRT: 20 MG/KG PROCEDURE SET: 1
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
143 143 617 12/31/01 645 01/28/02 2/22 Ulcer Site Of Application
REMOVED ** CID 143 ** REASON - MSAC
649 02/01/02 Ulcer/Abscess Appendage 2
649 02/01/02 Lethargic
649 02/01/02 Nasal/Eye Discharge
649 02/01/02 Ulcer Site Of Application
NTP EXP/TEST: 93020-07 DIISOPROPYLCARBODIIMIDE PAGE: 9
TEST TYPE: CHRONIC DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 06/30/04
ROUTE: SKIN APPLICATION EISRPT37 TIME: 11:15:09
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: RATS-F 344 TRT#: 7 ROOM/AREA: 21 FIRST DOSE: 04/24/00
SEX: MALE TRT: 40 MG/KG PROCEDURE SET: 1
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
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