TDMS Study 96022-02 Pathology Tables
NTP Experiment-Test: 96022-02 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a) Report: PEIRPT05
Study Type: CHRONIC TEF EVALUATION (PCB MIXTURE;PCB 126/PCB 118) Date: 04/27/04
Route: GAVAGE Time: 13:33:00
53 WEEK SSAC/FINAL#1
Facility: Battelle Columbus Laboratory
Chemical CAS #: TEFPCBMIX
Lock Date: 11/04/02
Cage Range: All
Reasons For Removal: 25017 Scheduled Sacrifice
Removal Date Range: 10/12/00 - 10/13/00
Treatment Groups: Include 001 0 NG / 0 UG
Include 002 80 NG /10 UG
Include 003 240 NG /30 UG
Include 004 800 NG /100 UG
Include 005 2400 NG/300 UG
Include 006 4000 NG/500 UG
a Number of animals examined microscopically at site and number of animals with lesion
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NTP Experiment-Test: 96022-02 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a) Report: PEIRPT05
Study Type: CHRONIC TEF EVALUATION (PCB MIXTURE;PCB 126/PCB 118) Date: 04/27/04
Route: GAVAGE Time: 13:33:00
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SPRAGUE-DAWLEY RATS FEMALE 0 NG / 80 NG / 240 NG / 800 NG / 2400 NG/ 4000 NG/
0 UG 10 UG 30 UG 100 UG 300 UG 500 UG
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DISPOSITION SUMMARY
Animals Initially in Study 98 86 98 86 98 86
Scheduled Sacrifice 13 12 13 13 13
Early Deaths
Survivors
Animals Examined Microscopically 8 7 8 8 8
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ALIMENTARY SYSTEM
None
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CARDIOVASCULAR SYSTEM
None
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ENDOCRINE SYSTEM
Adrenal Medulla (8) (1) (8)
Pheochromocytoma Benign 1 (100%)
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GENERAL BODY SYSTEM
None
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GENITAL SYSTEM
Uterus (8) (7) (8) (8) (8)
Polyp Stromal, Multiple 1 (13%)
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HEMATOPOIETIC SYSTEM
None
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NTP Experiment-Test: 96022-02 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a) Report: PEIRPT05
Study Type: CHRONIC TEF EVALUATION (PCB MIXTURE;PCB 126/PCB 118) Date: 04/27/04
Route: GAVAGE Time: 13:33:00
____________________________________________________________________________________________________________________________________
SPRAGUE-DAWLEY RATS FEMALE 0 NG / 80 NG / 240 NG / 800 NG / 2400 NG/ 4000 NG/
0 UG 10 UG 30 UG 100 UG 300 UG 500 UG
____________________________________________________________________________________________________________________________________
INTEGUMENTARY SYSTEM
Mammary Gland (8) (2) (1) (1) (8)
Fibroadenoma 1 (50%) 1 (100%) 1 (100%) 1 (13%)
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MUSCULOSKELETAL SYSTEM
None
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NERVOUS SYSTEM
None
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RESPIRATORY SYSTEM
Lung (8) (7) (8) (8) (8)
Cystic Keratinizing Epithelioma 4 (50%)
Cystic Keratinizing Epithelioma, Multiple 1 (13%) 1 (13%)
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SPECIAL SENSES SYSTEM
None
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URINARY SYSTEM
None
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NTP Experiment-Test: 96022-02 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a) Report: PEIRPT05
Study Type: CHRONIC TEF EVALUATION (PCB MIXTURE;PCB 126/PCB 118) Date: 04/27/04
Route: GAVAGE Time: 13:33:00
____________________________________________________________________________________________________________________________________
SPRAGUE-DAWLEY RATS FEMALE 0 NG / 80 NG / 240 NG / 800 NG / 2400 NG/ 4000 NG/
0 UG 10 UG 30 UG 100 UG 300 UG 500 UG
____________________________________________________________________________________________________________________________________
TUMOR SUMMARY
Total Animals with Primary Neoplasms (b) 1 2 2 5
Total Primary Neoplasms 1 2 2 7
Total Animals with Benign Neoplasms 1 2 2 5
Total Benign Neoplasms 1 2 2 7
Total Animals with Malignant Neoplasms
Total Malignant Neoplasms
Total Animals with Metastatic Neoplasms
Total Metastatic Neoplasm
Total Animals with Malignant Neoplasms
Uncertain Primary Site
Total Animals with Neoplasms Uncertain-
Benign or Malignant
Total Uncertain Neoplasms
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a Number of animals examined microscopically at site and number of animals with lesion
b Primary tumors: all tumors except metastatic tumors
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