TDMS Study 89029-01 Pathology Tables
NTP Experiment-Test: 89029-01 INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a) Report: PEIRPT03 Study Type: SUBCHRON 8-WEEK MAGNETIC FIELDS (EMF) Date: 10/25/04 Route: MAGNETIC FIELDS Time: 11:29:08 Facility: I. I. T. Research Institute Chemical CAS #: ELECTROMAG Lock Date: 03/24/94 Cage Range: All Reasons For Removal: All Removal Date Range: All Treatment Groups: Include All a Number of animals examined microscopically at site and number of animals with lesion Page 1 NTP Experiment-Test: 89029-01 INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a) Report: PEIRPT03 Study Type: SUBCHRON 8-WEEK MAGNETIC FIELDS (EMF) Date: 10/25/04 Route: MAGNETIC FIELDS Time: 11:29:08 ____________________________________________________________________________________________________________________________________ FISCHER 344 RATS FEMALE UNTREAT. .02 2 10 10 GAUSS CONTROL GAUSS GAUSS GAUSS INTER ____________________________________________________________________________________________________________________________________ DISPOSITION SUMMARY Animals Initially In Study 10 10 10 10 10 Early Deaths Natural Death 1 Survivors Terminal Sacrifice 10 10 9 10 10 Animals Examined Microscopically 10 10 10 10 10 ____________________________________________________________________________________________________________________________________ ALIMENTARY SYSTEM Liver (10) (10) (10) (10) (10) Fibrosis, Focal 1 (10%) Hemorrhage 1 (10%) Hepatodiaphragmatic Nodule 1 (10%) Mesentery (1) Fat, Necrosis 1 (100%) Pancreas (10) (10) (10) (10) (10) Acinus, Atrophy 2 (20%) 1 (10%) ____________________________________________________________________________________________________________________________________ CARDIOVASCULAR SYSTEM Heart (10) (10) (10) (10) (10) Cardiomyopathy 1 (10%) 1 (10%) 1 (10%) Fibrosis 1 (10%) ____________________________________________________________________________________________________________________________________ ENDOCRINE SYSTEM Adrenal Cortex (10) (10) (10) (10) (10) Hemorrhage 1 (10%) Pituitary Gland (10) (10) (10) (10) (10) Pars Distalis, Cyst 1 (10%) 1 (10%) Pars Distalis, Hyperplasia 1 (10%) 2 (20%) 1 (10%) 1 (10%) Pars Nervosa, Cyst 1 (10%) ____________________________________________________________________________________________________________________________________ GENERAL BODY SYSTEM None ____________________________________________________________________________________________________________________________________ a Number of animals examined microscopically at site and number of animals with lesion Page 2 NTP Experiment-Test: 89029-01 INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a) Report: PEIRPT03 Study Type: SUBCHRON 8-WEEK MAGNETIC FIELDS (EMF) Date: 10/25/04 Route: MAGNETIC FIELDS Time: 11:29:08 ____________________________________________________________________________________________________________________________________ FISCHER 344 RATS FEMALE UNTREAT. .02 2 10 10 GAUSS CONTROL GAUSS GAUSS GAUSS INTER ____________________________________________________________________________________________________________________________________ GENITAL SYSTEM Ovary (10) (10) (10) (10) (10) Cyst 1 (10%) 2 (20%) 2 (20%) Uterus (10) (10) (10) (10) (10) Hemorrhage 1 (10%) Hydrometra 1 (10%) 1 (10%) 2 (20%) 2 (20%) 5 (50%) ____________________________________________________________________________________________________________________________________ HEMATOPOIETIC SYSTEM Thymus (10) (10) (10) (10) (10) Hemorrhage 2 (20%) 2 (20%) 1 (10%) 1 (10%) 1 (10%) ____________________________________________________________________________________________________________________________________ INTEGUMENTARY SYSTEM None ____________________________________________________________________________________________________________________________________ MUSCULOSKELETAL SYSTEM None ____________________________________________________________________________________________________________________________________ NERVOUS SYSTEM None ____________________________________________________________________________________________________________________________________ RESPIRATORY SYSTEM Lung (10) (10) (10) (10) (10) Congestion 1 (10%) Hemorrhage 3 (30%) 1 (10%) Infiltration Cellular, Focal, Histiocyte 1 (10%) Inflammation, Chronic, Focal 1 (10%) Inflammation, Focal, Granulomatous 1 (10%) Metaplasia, Focal, Osseous 1 (10%) ____________________________________________________________________________________________________________________________________ SPECIAL SENSES SYSTEM a Number of animals examined microscopically at site and number of animals with lesion Page 3 NTP Experiment-Test: 89029-01 INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a) Report: PEIRPT03 Study Type: SUBCHRON 8-WEEK MAGNETIC FIELDS (EMF) Date: 10/25/04 Route: MAGNETIC FIELDS Time: 11:29:08 ____________________________________________________________________________________________________________________________________ FISCHER 344 RATS FEMALE UNTREAT. .02 2 10 10 GAUSS CONTROL GAUSS GAUSS GAUSS INTER ____________________________________________________________________________________________________________________________________ SPECIAL SENSES SYSTEM - CONT Harderian Gland (10) (10) (10) (10) (10) Infiltration Cellular, Lymphocyte 1 (10%) 1 (10%) 1 (10%) ____________________________________________________________________________________________________________________________________ URINARY SYSTEM Kidney (10) (10) (10) (10) (10) Angiectasis 1 (10%) Hydronephrosis 1 (10%) Mineralization 2 (20%) a Number of animals examined microscopically at site and number of animals with lesion Page 4 NTP Experiment-Test: 89029-01 INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a) Report: PEIRPT03 Study Type: SUBCHRON 8-WEEK MAGNETIC FIELDS (EMF) Date: 10/25/04 Route: MAGNETIC FIELDS Time: 11:29:08 ____________________________________________________________________________________________________________________________________ FISCHER 344 RATS MALE UNTREAT. .02 2 10 10 GAUSS CONTROL GAUSS GAUSS GAUSS INTER ____________________________________________________________________________________________________________________________________ DISPOSITION SUMMARY Animals Initially In Study 10 10 10 10 10 Early Deaths Survivors Terminal Sacrifice 10 10 10 10 10 Animals Examined Microscopically 10 10 10 10 10 ____________________________________________________________________________________________________________________________________ ALIMENTARY SYSTEM Liver (10) (10) (10) (10) (10) Congestion 1 (10%) Hematopoietic Cell Proliferation 1 (10%) 1 (10%) Hemorrhage 1 (10%) Hepatodiaphragmatic Nodule 1 (10%) Pancreas (10) (10) (10) (10) (10) Acinus, Atrophy, Focal 1 (10%) 1 (10%) ____________________________________________________________________________________________________________________________________ CARDIOVASCULAR SYSTEM Heart (10) (10) (10) (10) (10) Cardiomyopathy 7 (70%) 4 (40%) 5 (50%) 7 (70%) 6 (60%) ____________________________________________________________________________________________________________________________________ ENDOCRINE SYSTEM Pituitary Gland (10) (10) (10) (10) (10) Pars Distalis, Cyst 1 (10%) 1 (10%) 1 (10%) Pars Distalis, Hyperplasia 1 (10%) Thyroid Gland (10) (10) (10) (10) (10) Infiltration Cellular, Focal, Lymphocyte 1 (10%) ____________________________________________________________________________________________________________________________________ GENERAL BODY SYSTEM None ____________________________________________________________________________________________________________________________________ GENITAL SYSTEM None a Number of animals examined microscopically at site and number of animals with lesion Page 5 NTP Experiment-Test: 89029-01 INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a) Report: PEIRPT03 Study Type: SUBCHRON 8-WEEK MAGNETIC FIELDS (EMF) Date: 10/25/04 Route: MAGNETIC FIELDS Time: 11:29:08 ____________________________________________________________________________________________________________________________________ FISCHER 344 RATS MALE UNTREAT. .02 2 10 10 GAUSS CONTROL GAUSS GAUSS GAUSS INTER ____________________________________________________________________________________________________________________________________ HEMATOPOIETIC SYSTEM Spleen (10) (10) (10) (10) (10) Hemorrhage 1 (10%) Thymus (10) (10) (10) (10) (10) Hemorrhage 1 (10%) 1 (10%) 2 (20%) 3 (30%) 2 (20%) ____________________________________________________________________________________________________________________________________ INTEGUMENTARY SYSTEM None ____________________________________________________________________________________________________________________________________ MUSCULOSKELETAL SYSTEM Bone (10) (10) (10) (10) (10) Joint, Femur, Degeneration 1 (10%) ____________________________________________________________________________________________________________________________________ NERVOUS SYSTEM None ____________________________________________________________________________________________________________________________________ RESPIRATORY SYSTEM Lung (10) (10) (10) (10) (10) Hemorrhage 1 (10%) 2 (20%) 1 (10%) Inflammation, Chronic, Focal 1 (10%) Inflammation, Focal, Granulomatous 1 (10%) Metaplasia, Focal, Osseous 1 (10%) Trachea (10) (10) (10) (10) (10) Inflammation 1 (10%) ____________________________________________________________________________________________________________________________________ SPECIAL SENSES SYSTEM Harderian Gland (10) (10) (10) (10) (10) Infiltration Cellular, Lymphocyte 1 (10%) 3 (30%) ____________________________________________________________________________________________________________________________________ URINARY SYSTEM a Number of animals examined microscopically at site and number of animals with lesion Page 6 NTP Experiment-Test: 89029-01 INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a) Report: PEIRPT03 Study Type: SUBCHRON 8-WEEK MAGNETIC FIELDS (EMF) Date: 10/25/04 Route: MAGNETIC FIELDS Time: 11:29:08 ____________________________________________________________________________________________________________________________________ FISCHER 344 RATS MALE UNTREAT. .02 2 10 10 GAUSS CONTROL GAUSS GAUSS GAUSS INTER ____________________________________________________________________________________________________________________________________ URINARY SYSTEM - CONT Kidney (10) (10) (10) (10) (10) Infiltration Cellular, Focal, Lymphocyte 1 (10%) a Number of animals examined microscopically at site and number of animals with lesion Page 7 ------------------------------------------------------------ ---------- END OF REPORT ---------- ------------------------------------------------------------