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TDMS Study 89029-01 Pathology Tables

NTP Experiment-Test: 89029-01         INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a)               Report: PEIRPT03
Study Type: SUBCHRON 8-WEEK                               MAGNETIC FIELDS (EMF)                                   Date: 10/25/04
Route: MAGNETIC FIELDS                                                                                            Time: 11:29:08




       Facility:  I. I. T. Research Institute

       Chemical CAS #:  ELECTROMAG

       Lock Date:  03/24/94

       Cage Range:  All

       Reasons For Removal:    All

       Removal Date Range:     All

       Treatment Groups:       Include All




































a  Number of animals examined microscopically at site and number of animals with lesion

                                                              Page   1


NTP Experiment-Test: 89029-01         INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a)               Report: PEIRPT03  
Study Type: SUBCHRON 8-WEEK                               MAGNETIC FIELDS (EMF)                                   Date: 10/25/04    
Route: MAGNETIC FIELDS                                                                                            Time: 11:29:08    
____________________________________________________________________________________________________________________________________
                                                                                                                                    
         FISCHER 344 RATS FEMALE                   UNTREAT.     .02          2            10           10 GAUSS                     
                                                   CONTROL      GAUSS        GAUSS        GAUSS        INTER                        
____________________________________________________________________________________________________________________________________
                                                                                                                                    
DISPOSITION SUMMARY                                                                                                                 
                                                                                                                                    
  Animals Initially In Study                          10           10           10           10           10                        
  Early Deaths                                                                                                                      
    Natural Death                                                                1                                                  
  Survivors                                                                                                                         
    Terminal Sacrifice                                10           10            9           10           10                        
                                                                                                                                    
  Animals Examined Microscopically                    10           10           10           10           10                        
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 ALIMENTARY SYSTEM                                                                                                                  
                                                                                                                                    
   Liver                                              (10)         (10)         (10)         (10)         (10)                      
      Fibrosis, Focal                                                                         1 (10%)                               
      Hemorrhage                                                                                           1 (10%)                  
      Hepatodiaphragmatic Nodule                                                              1 (10%)                               
   Mesentery                                          (1)                                                                           
      Fat, Necrosis                                    1 (100%)                                                                     
   Pancreas                                           (10)         (10)         (10)         (10)         (10)                      
      Acinus, Atrophy                                  2 (20%)                                1 (10%)                               
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 CARDIOVASCULAR SYSTEM                                                                                                              
                                                                                                                                    
   Heart                                              (10)         (10)         (10)         (10)         (10)                      
      Cardiomyopathy                                   1 (10%)                                1 (10%)      1 (10%)                  
      Fibrosis                                                                                1 (10%)                               
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 ENDOCRINE SYSTEM                                                                                                                   
                                                                                                                                    
   Adrenal Cortex                                     (10)         (10)         (10)         (10)         (10)                      
      Hemorrhage                                                                              1 (10%)                               
   Pituitary Gland                                    (10)         (10)         (10)         (10)         (10)                      
      Pars Distalis, Cyst                              1 (10%)                                             1 (10%)                  
      Pars Distalis, Hyperplasia                       1 (10%)                   2 (20%)      1 (10%)      1 (10%)                  
      Pars Nervosa, Cyst                                                                                   1 (10%)                  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 GENERAL BODY SYSTEM                                                                                                                
                                                                                                                                    
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
a  Number of animals examined microscopically at site and number of animals with lesion                                             
                                                                                                                                    
                                                             Page    2                                                              
                                                                                                                                   
NTP Experiment-Test: 89029-01         INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a)               Report: PEIRPT03  
Study Type: SUBCHRON 8-WEEK                               MAGNETIC FIELDS (EMF)                                   Date: 10/25/04    
Route: MAGNETIC FIELDS                                                                                            Time: 11:29:08    
____________________________________________________________________________________________________________________________________
                                                                                                                                    
         FISCHER 344 RATS FEMALE                   UNTREAT.     .02          2            10           10 GAUSS                     
                                                   CONTROL      GAUSS        GAUSS        GAUSS        INTER                        
____________________________________________________________________________________________________________________________________
                                                                                                                                    
                                                                                                                                    
 GENITAL SYSTEM                                                                                                                     
                                                                                                                                    
   Ovary                                              (10)         (10)         (10)         (10)         (10)                      
      Cyst                                                          1 (10%)      2 (20%)                   2 (20%)                  
   Uterus                                             (10)         (10)         (10)         (10)         (10)                      
      Hemorrhage                                                                              1 (10%)                               
      Hydrometra                                       1 (10%)      1 (10%)      2 (20%)      2 (20%)      5 (50%)                  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 HEMATOPOIETIC SYSTEM                                                                                                               
                                                                                                                                    
   Thymus                                             (10)         (10)         (10)         (10)         (10)                      
      Hemorrhage                                       2 (20%)      2 (20%)      1 (10%)      1 (10%)      1 (10%)                  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 INTEGUMENTARY SYSTEM                                                                                                               
                                                                                                                                    
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 MUSCULOSKELETAL SYSTEM                                                                                                             
                                                                                                                                    
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 NERVOUS SYSTEM                                                                                                                     
                                                                                                                                    
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 RESPIRATORY SYSTEM                                                                                                                 
                                                                                                                                    
   Lung                                               (10)         (10)         (10)         (10)         (10)                      
      Congestion                                                                 1 (10%)                                            
      Hemorrhage                                       3 (30%)                   1 (10%)                                            
      Infiltration Cellular, Focal, Histiocyte                      1 (10%)                                                         
      Inflammation, Chronic, Focal                                                                         1 (10%)                  
      Inflammation, Focal, Granulomatous                                                      1 (10%)                               
      Metaplasia, Focal, Osseous                                                 1 (10%)                                            
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 SPECIAL SENSES SYSTEM                                                                                                              
                                                                                                                                    
                                                                                                                                    
a  Number of animals examined microscopically at site and number of animals with lesion                                             
                                                                                                                                    
                                                             Page    3                                                              
                                                                                                                                   
NTP Experiment-Test: 89029-01         INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a)               Report: PEIRPT03  
Study Type: SUBCHRON 8-WEEK                               MAGNETIC FIELDS (EMF)                                   Date: 10/25/04    
Route: MAGNETIC FIELDS                                                                                            Time: 11:29:08    
____________________________________________________________________________________________________________________________________
                                                                                                                                    
         FISCHER 344 RATS FEMALE                   UNTREAT.     .02          2            10           10 GAUSS                     
                                                   CONTROL      GAUSS        GAUSS        GAUSS        INTER                        
____________________________________________________________________________________________________________________________________
                                                                                                                                    
SPECIAL SENSES SYSTEM - CONT                                                                                                        
   Harderian Gland                                    (10)         (10)         (10)         (10)         (10)                      
      Infiltration Cellular, Lymphocyte                1 (10%)      1 (10%)                   1 (10%)                               
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 URINARY SYSTEM                                                                                                                     
                                                                                                                                    
   Kidney                                             (10)         (10)         (10)         (10)         (10)                      
      Angiectasis                                      1 (10%)                                                                      
      Hydronephrosis                                                                                       1 (10%)                  
      Mineralization                                                                          2 (20%)                               
                                                                                                                                    
                                                                                                                                    
a  Number of animals examined microscopically at site and number of animals with lesion                                             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page    4                                                              
                                                                                                                                   
NTP Experiment-Test: 89029-01         INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a)               Report: PEIRPT03  
Study Type: SUBCHRON 8-WEEK                               MAGNETIC FIELDS (EMF)                                   Date: 10/25/04    
Route: MAGNETIC FIELDS                                                                                            Time: 11:29:08    
____________________________________________________________________________________________________________________________________
                                                                                                                                    
         FISCHER 344 RATS MALE                     UNTREAT.     .02          2            10           10 GAUSS                     
                                                   CONTROL      GAUSS        GAUSS        GAUSS        INTER                        
____________________________________________________________________________________________________________________________________
                                                                                                                                    
DISPOSITION SUMMARY                                                                                                                 
                                                                                                                                    
  Animals Initially In Study                          10           10           10           10           10                        
  Early Deaths                                                                                                                      
  Survivors                                                                                                                         
    Terminal Sacrifice                                10           10           10           10           10                        
                                                                                                                                    
  Animals Examined Microscopically                    10           10           10           10           10                        
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 ALIMENTARY SYSTEM                                                                                                                  
                                                                                                                                    
   Liver                                              (10)         (10)         (10)         (10)         (10)                      
      Congestion                                                                 1 (10%)                                            
      Hematopoietic Cell Proliferation                                           1 (10%)                   1 (10%)                  
      Hemorrhage                                       1 (10%)                                                                      
      Hepatodiaphragmatic Nodule                       1 (10%)                                                                      
   Pancreas                                           (10)         (10)         (10)         (10)         (10)                      
      Acinus, Atrophy, Focal                           1 (10%)                   1 (10%)                                            
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 CARDIOVASCULAR SYSTEM                                                                                                              
                                                                                                                                    
   Heart                                              (10)         (10)         (10)         (10)         (10)                      
      Cardiomyopathy                                   7 (70%)      4 (40%)      5 (50%)      7 (70%)      6 (60%)                  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 ENDOCRINE SYSTEM                                                                                                                   
                                                                                                                                    
   Pituitary Gland                                    (10)         (10)         (10)         (10)         (10)                      
      Pars Distalis, Cyst                              1 (10%)                   1 (10%)                   1 (10%)                  
      Pars Distalis, Hyperplasia                                                                           1 (10%)                  
   Thyroid Gland                                      (10)         (10)         (10)         (10)         (10)                      
      Infiltration Cellular, Focal, Lymphocyte                                                             1 (10%)                  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 GENERAL BODY SYSTEM                                                                                                                
                                                                                                                                    
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 GENITAL SYSTEM                                                                                                                     
                                                                                                                                    
   None                                                                                                                             
                                                                                                                                    
a  Number of animals examined microscopically at site and number of animals with lesion                                             
                                                                                                                                    
                                                             Page    5                                                              
                                                                                                                                   
NTP Experiment-Test: 89029-01         INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a)               Report: PEIRPT03  
Study Type: SUBCHRON 8-WEEK                               MAGNETIC FIELDS (EMF)                                   Date: 10/25/04    
Route: MAGNETIC FIELDS                                                                                            Time: 11:29:08    
____________________________________________________________________________________________________________________________________
                                                                                                                                    
         FISCHER 344 RATS MALE                     UNTREAT.     .02          2            10           10 GAUSS                     
                                                   CONTROL      GAUSS        GAUSS        GAUSS        INTER                        
____________________________________________________________________________________________________________________________________
                                                                                                                                    
                                                                                                                                    
 HEMATOPOIETIC SYSTEM                                                                                                               
                                                                                                                                    
   Spleen                                             (10)         (10)         (10)         (10)         (10)                      
      Hemorrhage                                                                 1 (10%)                                            
   Thymus                                             (10)         (10)         (10)         (10)         (10)                      
      Hemorrhage                                       1 (10%)      1 (10%)      2 (20%)      3 (30%)      2 (20%)                  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 INTEGUMENTARY SYSTEM                                                                                                               
                                                                                                                                    
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 MUSCULOSKELETAL SYSTEM                                                                                                             
                                                                                                                                    
   Bone                                               (10)         (10)         (10)         (10)         (10)                      
      Joint, Femur, Degeneration                                                                           1 (10%)                  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 NERVOUS SYSTEM                                                                                                                     
                                                                                                                                    
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 RESPIRATORY SYSTEM                                                                                                                 
                                                                                                                                    
   Lung                                               (10)         (10)         (10)         (10)         (10)                      
      Hemorrhage                                                                 1 (10%)      2 (20%)      1 (10%)                  
      Inflammation, Chronic, Focal                                  1 (10%)                                                         
      Inflammation, Focal, Granulomatous               1 (10%)                                                                      
      Metaplasia, Focal, Osseous                       1 (10%)                                                                      
   Trachea                                            (10)         (10)         (10)         (10)         (10)                      
      Inflammation                                                  1 (10%)                                                         
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 SPECIAL SENSES SYSTEM                                                                                                              
                                                                                                                                    
   Harderian Gland                                    (10)         (10)         (10)         (10)         (10)                      
      Infiltration Cellular, Lymphocyte                1 (10%)                                3 (30%)                               
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 URINARY SYSTEM                                                                                                                     
                                                                                                                                    
                                                                                                                                    
a  Number of animals examined microscopically at site and number of animals with lesion                                             
                                                                                                                                    
                                                             Page    6                                                              
                                                                                                                                   
NTP Experiment-Test: 89029-01         INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a)               Report: PEIRPT03  
Study Type: SUBCHRON 8-WEEK                               MAGNETIC FIELDS (EMF)                                   Date: 10/25/04    
Route: MAGNETIC FIELDS                                                                                            Time: 11:29:08    
____________________________________________________________________________________________________________________________________
                                                                                                                                    
         FISCHER 344 RATS MALE                     UNTREAT.     .02          2            10           10 GAUSS                     
                                                   CONTROL      GAUSS        GAUSS        GAUSS        INTER                        
____________________________________________________________________________________________________________________________________
                                                                                                                                    
URINARY SYSTEM - CONT                                                                                                               
   Kidney                                             (10)         (10)         (10)         (10)         (10)                      
      Infiltration Cellular, Focal, Lymphocyte                                                1 (10%)                               
                                                                                                                                    
                                                                                                                                    
a  Number of animals examined microscopically at site and number of animals with lesion                                             
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                                                                                                    
                                                             Page    7                                                              
                                                                                                                                   
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                             ----------              END OF REPORT             ----------                                           
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