TDMS Study 88139-05 Pathology Tables
NTP Experiment-Test: 88139-05 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02
Study Type: SUBCHRON 90-DAY BENZYLTRIMETHYLAMMONIUM CHLORIDE(BTMAC) Date: 05/12/97
Route: GAVAGE Time: 14:22:39
13 WEEK SYBCHRONIC
Facility: Microbiological Associates
Chemical CAS #: 56-93-9
Lock Date: 05/18/94
Cage Range: All
Reasons For Removal: All
Removal Date Range: All
Treatment Groups: Include All
a Number of animals examined microscopically at site and number of animals with lesion
Page 1
NTP Experiment-Test: 88139-05 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02
Study Type: SUBCHRON 90-DAY BENZYLTRIMETHYLAMMONIUM CHLORIDE(BTMAC) Date: 05/12/97
Route: GAVAGE Time: 14:22:39
____________________________________________________________________________________________________________________________________
FISCHER 344 RATS FEMALE CONTROL 12.5 25.0 50.0 100.0
MG/KG MG/KG MG/KG MG/KG
____________________________________________________________________________________________________________________________________
DISPOSITION SUMMARY
Animals Initially in Study 10 10 10 10 10
Early Deaths
Dosing Accident 1
Natural Death 2
Survivors
Terminal Sacrifice 10 10 9 9 8
Accidently Killed 1
Animals Examined Microscopically 10 3 2 10 10
____________________________________________________________________________________________________________________________________
ALIMENTARY SYSTEM
None
____________________________________________________________________________________________________________________________________
CARDIOVASCULAR SYSTEM
None
____________________________________________________________________________________________________________________________________
ENDOCRINE SYSTEM
None
____________________________________________________________________________________________________________________________________
GENERAL BODY SYSTEM
None
____________________________________________________________________________________________________________________________________
GENITAL SYSTEM
None
____________________________________________________________________________________________________________________________________
HEMATOPOIETIC SYSTEM
None
____________________________________________________________________________________________________________________________________
Page 2
NTP Experiment-Test: 88139-05 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02
Study Type: SUBCHRON 90-DAY BENZYLTRIMETHYLAMMONIUM CHLORIDE(BTMAC) Date: 05/12/97
Route: GAVAGE Time: 14:22:39
____________________________________________________________________________________________________________________________________
FISCHER 344 RATS FEMALE CONTROL 12.5 25.0 50.0 100.0
MG/KG MG/KG MG/KG MG/KG
____________________________________________________________________________________________________________________________________
INTEGUMENTARY SYSTEM
None
____________________________________________________________________________________________________________________________________
MUSCULOSKELETAL SYSTEM
None
____________________________________________________________________________________________________________________________________
NERVOUS SYSTEM
None
____________________________________________________________________________________________________________________________________
RESPIRATORY SYSTEM
None
____________________________________________________________________________________________________________________________________
SPECIAL SENSES SYSTEM
None
____________________________________________________________________________________________________________________________________
URINARY SYSTEM
None
Page 3
NTP Experiment-Test: 88139-05 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02
Study Type: SUBCHRON 90-DAY BENZYLTRIMETHYLAMMONIUM CHLORIDE(BTMAC) Date: 05/12/97
Route: GAVAGE Time: 14:22:39
____________________________________________________________________________________________________________________________________
FISCHER 344 RATS MALE CONTROL 12.5 25.0 50.0 100.0
MG/KG MG/KG MG/KG MG/KG
____________________________________________________________________________________________________________________________________
DISPOSITION SUMMARY
Animals Initially in Study 10 10 10 10 10
Early Deaths
Survivors
Terminal Sacrifice 10 10 10 10 10
Animals Examined Microscopically 10 2 1 10 10
____________________________________________________________________________________________________________________________________
ALIMENTARY SYSTEM
None
____________________________________________________________________________________________________________________________________
CARDIOVASCULAR SYSTEM
None
____________________________________________________________________________________________________________________________________
ENDOCRINE SYSTEM
None
____________________________________________________________________________________________________________________________________
GENERAL BODY SYSTEM
None
____________________________________________________________________________________________________________________________________
GENITAL SYSTEM
None
____________________________________________________________________________________________________________________________________
HEMATOPOIETIC SYSTEM
None
____________________________________________________________________________________________________________________________________
INTEGUMENTARY SYSTEM
None
____________________________________________________________________________________________________________________________________
Page 4
NTP Experiment-Test: 88139-05 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02
Study Type: SUBCHRON 90-DAY BENZYLTRIMETHYLAMMONIUM CHLORIDE(BTMAC) Date: 05/12/97
Route: GAVAGE Time: 14:22:39
____________________________________________________________________________________________________________________________________
FISCHER 344 RATS MALE CONTROL 12.5 25.0 50.0 100.0
MG/KG MG/KG MG/KG MG/KG
____________________________________________________________________________________________________________________________________
MUSCULOSKELETAL SYSTEM
None
____________________________________________________________________________________________________________________________________
NERVOUS SYSTEM
None
____________________________________________________________________________________________________________________________________
RESPIRATORY SYSTEM
None
____________________________________________________________________________________________________________________________________
SPECIAL SENSES SYSTEM
None
____________________________________________________________________________________________________________________________________
URINARY SYSTEM
None
Page 5
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