TDMS Study 88138-03 Pathology Tables
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: Battelle Columbus BENZOPHENONE DATE: 07/21/03
EXPERIMENT: 88138 TEST: 03 TIME: 15:06:19
CAGES FROM 0000 TO LAST CAGE PAGE: 1
TEST TYPE: CHRONIC ROUTE: DOSED FEED NTP: C88138B
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REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: BATTELLE COLUMBUS BENZOPHENONE DATE: 07/21/03
EXPERIMENT: 88138 TEST: 03 TIME: 15:16:21
SPECIES: RATS, FISCHER 344
TEST TYPE: TWO YEAR ROUTE: DOSED FEED NTP: 88138B
CONT: N01-ES-55388 CAS: 119-61-9
MEAN BODY WEIGHTS AND SURVIVAL OF MALE RATS IN THE
TWO YEAR DOSED FEED STUDY OF BENZOPHENONE
==========================================================================================================
WEEK 0 PPM 312 PPM 625 PPM 1250 PPM
---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
=========================================================================================================
B 108.3 50 109.4 101.0 50 108.6 100.3 50 110.0 101.6 50
1 108.3 50 109.4 101.0 50 108.6 100.3 50 110.0 101.6 50
2 144.0 50 148.1 102.8 50 146.0 101.4 50 141.8 98.5 50
6 265.9 50 268.2 100.9 50 266.3 100.2 50 263.8 99.2 50
10 319.3 50 317.9 99.6 50 319.4 100.0 50 316.3 99.1 50
14 351.8 50 351.5 99.9 50 350.4 99.6 50 352.6 100.2 50
18 379.4 50 380.1 100.2 50 371.5 97.9 50 372.0 98.0 50
22 393.8 50 391.6 99.4 50 388.2 98.6 50 387.7 98.5 50
26 416.1 50 413.0 99.3 50 407.0 97.8 50 406.5 97.7 50
30 426.1 50 427.0 100.2 50 423.6 99.4 50 423.0 99.3 50
34 442.4 50 442.5 100.0 50 437.5 98.9 50 436.2 98.6 50
38 452.7 50 455.4 100.6 50 448.9 99.2 50 447.1 98.8 50
41 456.6 50 460.2 100.8 50 456.7 100.0 50 450.2 98.6 50
46 471.5 50 463.1 98.2 50 468.3 99.3 50 462.2 98.0 50
50 478.1 50 475.5 99.5 50 473.2 99.0 50 464.7 97.2 50
54 482.3 50 478.5 99.2 49 478.7 99.3 50 466.1 96.6 50
58 489.2 50 488.3 99.8 48 485.7 99.3 50 470.6 96.2 50
62 493.9 49 492.8 99.8 48 491.2 99.5 50 471.6 95.5 50
66 498.6 49 494.7 99.2 48 497.2 99.7 50 472.2 94.7 50
70 492.4 49 494.3 100.4 47 484.5 98.4 50 458.0 93.0 50
74 497.6 47 491.4 98.8 46 490.0 98.5 47 449.4 90.3 47
78 498.6 47 492.6 98.8 44 483.7 97.0 47 435.5 87.3 42
82 500.2 45 496.2 99.2 43 479.4 95.8 45 424.2 84.8 39
86 501.7 43 493.8 98.4 42 480.7 95.8 44 410.5 81.8 34
90 496.7 43 486.1 97.9 40 471.0 94.8 43 384.4 77.4 27
94 486.9 39 481.8 99.0 38 462.5 95.0 42 378.7 77.8 16
98 478.2 34 478.4 100.0 35 443.8 92.8 41 343.3 71.8 11
102 476.7 27 459.5 96.4 31 422.1 88.5 37 305.6 64.1 8
TERM. SAC. 22 27 31 2
==========================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.
MEAN BODY WEIGHTS AND SURVIVAL OF FEMALE RATS IN THE
TWO YEAR DOSED FEED STUDY OF BENZOPHENONE
==========================================================================================================
WEEK 0 PPM 312 PPM 625 PPM 1250 PPM
---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
=========================================================================================================
B 100.9 50 100.6 99.7 50 99.8 98.9 50 99.7 98.8 50
1 100.9 50 100.6 99.7 50 99.8 98.9 50 99.7 98.8 50
2 119.9 50 120.0 100.1 50 118.9 99.2 50 117.7 98.2 50
6 169.4 50 168.6 99.5 50 164.7 97.2 50 161.2 95.2 50
10 189.4 50 186.4 98.4 50 183.8 97.0 50 179.0 94.5 50
14 201.9 50 194.6 96.4 50 191.4 94.8 50 187.4 92.8 50
18 213.5 50 204.8 95.9 50 200.6 94.0 50 193.4 90.6 50
22 218.8 50 210.4 96.2 50 206.0 94.1 50 197.9 90.4 50
26 223.5 50 213.7 95.6 50 209.8 93.9 50 201.6 90.2 50
30 233.6 50 222.1 95.1 50 216.4 92.6 50 209.9 89.9 50
34 240.5 50 227.2 94.5 50 221.2 92.0 50 212.9 88.5 50
38 248.7 50 234.9 94.5 50 228.3 91.8 50 219.2 88.1 50
41 254.0 50 240.2 94.6 50 232.9 91.7 50 222.3 87.5 50
46 264.1 49 249.2 94.4 50 237.4 89.9 50 222.0 84.1 50
50 274.6 49 258.1 94.0 50 244.7 89.1 50 231.1 84.2 50
54 283.2 48 267.5 94.5 50 252.6 89.2 50 235.9 83.3 50
58 290.4 48 273.2 94.1 50 257.9 88.8 50 239.1 82.3 50
62 302.2 48 289.6 95.8 50 272.3 90.1 50 250.1 82.8 50
66 313.4 47 297.6 95.0 50 278.6 88.9 50 256.1 81.7 50
70 318.3 47 305.8 96.1 50 286.8 90.1 50 264.5 83.1 49
74 327.6 47 313.3 95.6 50 293.9 89.7 50 271.6 82.9 49
78 331.2 46 317.0 95.7 50 300.2 90.6 49 275.8 83.3 48
82 337.6 45 324.1 96.0 50 309.0 91.5 49 283.5 84.0 48
86 343.6 45 327.9 95.4 50 313.4 91.2 49 287.3 83.6 47
90 346.6 43 331.7 95.7 47 312.4 90.1 48 287.2 82.9 46
94 345.8 41 332.6 96.2 46 315.3 91.2 46 288.9 83.5 45
98 348.7 40 336.7 96.6 45 314.3 90.1 44 291.4 83.6 41
102 344.5 37 337.0 97.8 41 313.0 90.9 40 294.8 85.6 37
TERM. SAC. 32 38 37 34
==========================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.