TDMS Study 05206-05 Pathology Tables
NTP Experiment-Test: 05206-05 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02
Study Type: SUBCHRON 90-DAY CUPRIC SULFATE Date: 10/15/04
Route: DOSED FEED Time: 08:19:29
Facility: Battelle Columbus Laboratory
Chemical CAS #: 7758-99-8
Lock Date: None
Cage Range: All
Reasons For Removal: All
Removal Date Range: All
Treatment Groups: Include 002 0 PPM
Include 001 0 PPM
Include 006 500 PPM
Include 005 500 PPM
Include 010 1000 PPM
Include 009 1000 PPM
Include 014 2000 PPM
Include 013 2000 PPM
Include 018 4000 PPM
Include 017 4000 PPM
Include 022 8000 PPM
Include 021 8000 PPM
a Number of animals examined microscopically at site and number of animals with lesion
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NTP Experiment-Test: 05206-05 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02
Study Type: SUBCHRON 90-DAY CUPRIC SULFATE Date: 10/15/04
Route: DOSED FEED Time: 08:19:29
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FISCHER 344 RATS FEMALE 0 PPM 500 PPM 1000 PPM 2000 PPM 4000 PPM 8000 PPM
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DISPOSITION SUMMARY
Animals Initially in Study 10 10 10 10 10 10
Early Deaths
Accidently Killed 1
Survivors
Terminal Sacrifice 10 10 9 10 10 10
Animals Examined Microscopically 10 10 10 10 10 10
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ALIMENTARY SYSTEM
None
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CARDIOVASCULAR SYSTEM
None
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ENDOCRINE SYSTEM
None
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GENERAL BODY SYSTEM
None
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GENITAL SYSTEM
None
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HEMATOPOIETIC SYSTEM
None
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NTP Experiment-Test: 05206-05 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02
Study Type: SUBCHRON 90-DAY CUPRIC SULFATE Date: 10/15/04
Route: DOSED FEED Time: 08:19:29
____________________________________________________________________________________________________________________________________
FISCHER 344 RATS FEMALE 0 PPM 500 PPM 1000 PPM 2000 PPM 4000 PPM 8000 PPM
____________________________________________________________________________________________________________________________________
INTEGUMENTARY SYSTEM
None
____________________________________________________________________________________________________________________________________
MUSCULOSKELETAL SYSTEM
None
____________________________________________________________________________________________________________________________________
NERVOUS SYSTEM
None
____________________________________________________________________________________________________________________________________
RESPIRATORY SYSTEM
None
____________________________________________________________________________________________________________________________________
SPECIAL SENSES SYSTEM
None
____________________________________________________________________________________________________________________________________
URINARY SYSTEM
None
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NTP Experiment-Test: 05206-05 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02
Study Type: SUBCHRON 90-DAY CUPRIC SULFATE Date: 10/15/04
Route: DOSED FEED Time: 08:19:29
____________________________________________________________________________________________________________________________________
FISCHER 344 RATS MALE 0 PPM 500 PPM 1000 PPM 2000 PPM 4000 PPM 8000 PPM
____________________________________________________________________________________________________________________________________
DISPOSITION SUMMARY
Animals Initially in Study 10 10 10 10 10 10
Early Deaths
Survivors
Terminal Sacrifice 10 10 10 10 10 10
Animals Examined Microscopically 10 10 10 10 10 10
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ALIMENTARY SYSTEM
Stomach, Forestomach (10) (1) (10) (10) (10) (10)
Fibroma 1 (100%)
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CARDIOVASCULAR SYSTEM
None
____________________________________________________________________________________________________________________________________
ENDOCRINE SYSTEM
None
____________________________________________________________________________________________________________________________________
GENERAL BODY SYSTEM
None
____________________________________________________________________________________________________________________________________
GENITAL SYSTEM
None
____________________________________________________________________________________________________________________________________
HEMATOPOIETIC SYSTEM
None
____________________________________________________________________________________________________________________________________
Page 4
NTP Experiment-Test: 05206-05 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02
Study Type: SUBCHRON 90-DAY CUPRIC SULFATE Date: 10/15/04
Route: DOSED FEED Time: 08:19:29
____________________________________________________________________________________________________________________________________
FISCHER 344 RATS MALE 0 PPM 500 PPM 1000 PPM 2000 PPM 4000 PPM 8000 PPM
____________________________________________________________________________________________________________________________________
INTEGUMENTARY SYSTEM
None
____________________________________________________________________________________________________________________________________
MUSCULOSKELETAL SYSTEM
None
____________________________________________________________________________________________________________________________________
NERVOUS SYSTEM
None
____________________________________________________________________________________________________________________________________
RESPIRATORY SYSTEM
None
____________________________________________________________________________________________________________________________________
SPECIAL SENSES SYSTEM
None
____________________________________________________________________________________________________________________________________
URINARY SYSTEM
None
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NTP Experiment-Test: 05206-05 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02
Study Type: SUBCHRON 90-DAY CUPRIC SULFATE Date: 10/15/04
Route: DOSED FEED Time: 08:19:29
____________________________________________________________________________________________________________________________________
FISCHER 344 RATS MALE 0 PPM 500 PPM 1000 PPM 2000 PPM 4000 PPM 8000 PPM
____________________________________________________________________________________________________________________________________
TUMOR SUMMARY
Total Animals with Primary Neoplasms (b) 1
Total Primary Neoplasms 1
Total Animals with Benign Neoplasms 1
Total Benign Neoplasms 1
Total Animals with Malignant Neoplasms
Total Malignant Neoplasms
Total Animals with Metastatic Neoplasms
Total Metastatic Neoplasm
Total Animals with Malignant Neoplasms
Uncertain Primary Site
Total Animals with Neoplasms Uncertain-
Benign or Malignant
Total Uncertain Neoplasms
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a Number of animals examined microscopically at site and number of animals with lesion
b Primary tumors: all tumors except metastatic tumors
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