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TDMS Study 96021-01 Pathology Tables

NTP  EXP/TEST: 96021-01                  TOXIC EQUIVALENCY FACTOR EVALUATION (PCB 153)                            PAGE: 1
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 06/05/03
ROUTE: GAVAGE                                                                                                     TIME: 10:28:46

                                                         EIS REPORT 03


       FACILITY:  Battelle Columbus Laboratory

       NTP C#:  C96021

       CONTRACT NUMBER:  NO1-ES-75411

       CAS NUMBER:  35065-27-1

       ANIMAL SUPPLIER:  HARLAN SPRAGUE-DAWLEY

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 96021-01                  TOXIC EQUIVALENCY FACTOR EVALUATION (PCB 153)                            PAGE: 2
TEST TYPE: CHRONIC                              INITIAL AND CURRENT BODY WEIGHT                                   DATE: 06/05/03
ROUTE: GAVAGE                                               EISRPT03                                              TIME: 10:28:46
----------------------------------------------------------------------------------------------------------------------------------
 SPECIES-STRAIN: SD-RATS                    SEX: FEMALE      WEEK ON DOSE: 105    FIRST DOSE: 08/24/98
----------------------------------------------------------------------------------------------------------------------------------
                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0 UG/KG            98    172.6    8.4        24    387.7   42.6                     24    217.2   42.0

 10 UG/KG           86    174.4    8.9        16    385.6   32.9        99.4         16    212.7   35.9

 100     UG/KG      98    173.6    8.9        28    403.6   50.1       104.1         28    227.9   49.4

 300     UG/KG      98    173.2    9.2        20    383.2   46.9        98.8         20    211.7   45.4

 1000    UG/KG      98    170.6   10.2        20    373.9   46.2        96.4         20    204.2   43.0

 3000    UG/KG      80    173.9    7.9        21    354.8   38.9        91.5         21    180.5   37.4

 3000 UG/KG STOP    50    170.3    8.3        20    395.6   44.5       102.0         20    225.4   44.6

                                               -----------------------------------
                                               ---------- END-OF-REPORT ----------
                                               -----------------------------------