TDMS Study 96017-06 Pathology Tables
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: Southern Research Inst WATER DISINFECTION BYPRODUCTS (DIBROMOACETIC ACID) DATE: 05/19/04
EXPERIMENT: 96017 TEST: 06 TIME: 09:02:07
CAGES FROM 0000 TO LAST CAGE PAGE: 1
TEST TYPE: CHRONIC ROUTE: DOSED WATER NTP: C96017
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REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: SOUTHERN RESEARCH INSTITUTE WATER DISINFECTION BYPRODUCTS (DIBROMOACETIC ACID) DATE: 05/19/04
EXPERIMENT: 96017 TEST: 06 TIME: 9:18:30
SPECIES: MICE, B6C3F1
TEST TYPE: TWO YEAR ROUTE: DOSED WATER NTP: C96017
CONT: N01-ES-85420 CAS: 631-64-1
MEAN BODY WEIGHTS AND SURVIVAL OF MALE MICE IN THE
TWO YEAR DOSED WATER STUDY OF WATER DISINFECTION BYPRODUCTS (DIBROMOACETIC ACID)
==========================================================================================================
WEEK 0 MG/L 50 MG/L 500 MG/L 1000 MG/L
---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
=========================================================================================================
B 21.9 50 22.1 100.9 50 22.4 102.3 50 22.5 102.7 50
1 21.9 50 22.1 100.9 50 22.4 102.3 50 22.5 102.7 50
2 24.2 50 24.4 100.8 50 24.9 102.9 50 24.7 102.1 50
3 25.7 50 25.9 100.8 50 26.3 102.3 50 26.2 101.9 50
4 27.1 50 27.4 101.1 50 27.8 102.6 50 27.5 101.5 50
5 28.9 50 29.2 101.0 50 29.3 101.4 50 29.1 100.7 50
6 30.2 50 30.6 101.3 50 30.6 101.3 50 30.1 99.7 50
7 31.9 50 32.4 101.6 50 32.2 100.9 50 31.9 100.0 50
8 33.4 50 33.8 101.2 50 33.4 100.0 50 33.1 99.1 50
9 34.8 50 35.1 100.9 50 34.4 98.9 50 33.9 97.4 50
10 35.9 50 36.3 101.1 50 35.6 99.2 50 35.2 98.1 50
11 37.4 50 37.9 101.3 50 36.9 98.7 50 36.6 97.9 50
12 38.3 50 39.1 102.1 50 38.3 100.0 50 37.8 98.7 50
13 39.7 45* 40.2 101.3 50 39.3 99.0 50 38.9 98.0 50
17 43.7 50 44.8 102.5 50 43.0 98.4 50 42.7 97.7 50
21 47.0 50 47.8 101.7 50 46.8 99.6 50 46.5 98.9 50
25 49.4 50 49.6 100.4 50 48.9 99.0 50 49.3 99.8 50
29 50.0 50 50.5 101.0 50 49.8 99.6 50 50.0 100.0 50
33 50.9 49 51.3 100.8 50 50.5 99.2 50 50.8 99.8 50
37 52.2 49 52.6 100.8 50 51.7 99.0 50 51.8 99.2 50
41 52.1 49 52.9 101.5 50 52.2 100.2 50 52.2 100.2 50
45 52.2 49 52.5 100.6 49 52.3 100.2 50 52.3 100.2 50
49 52.1 49 53.0 101.7 49 52.4 100.6 50 52.8 101.3 50
53 52.2 49 53.3 102.1 49 52.6 100.8 50 53.1 101.7 50
57 51.1 49 52.7 103.1 49 52.6 102.9 49 52.8 103.3 50
61 52.0 49 53.3 102.5 49 53.1 102.1 49 53.1 102.1 50
65 52.5 48 54.0 102.9 49 53.4 101.7 48 53.8 102.5 50
69 51.7 46 54.0 104.4 49 53.3 103.1 48 52.6 101.7 48
73 52.1 45 54.1 103.8 49 53.0 101.7 48 52.6 101.0 47
77 51.6 44 53.8 104.3 49 52.9 102.5 47 52.0 100.8 47
81 51.8 44 53.8 103.9 48 52.1 100.6 47 52.0 100.4 46
85 50.7 44 52.8 104.1 46 51.9 102.4 45 50.5 99.6 45
89 48.7 42 51.7 106.2 45 51.5 105.7 43 50.3 103.3 44
93 48.1 39 51.0 106.0 45 51.6 107.3 40 49.3 102.5 41
97 47.3 36 49.9 105.5 43 50.5 106.8 38 48.3 102.1 38
101 46.7 36 50.0 107.1 40 51.1 109.4 36 46.6 99.8 34
TERM. SAC. 31 38 34 31
==========================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.
MEAN BODY WEIGHTS AND SURVIVAL OF FEMALE MICE IN THE
TWO YEAR DOSED WATER STUDY OF WATER DISINFECTION BYPRODUCTS (DIBROMOACETIC ACID)
==========================================================================================================
WEEK 0 MG/L 50 MG/L 500 MG/L 1000 MG/L
---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
=========================================================================================================
B 18.4 50 18.6 101.1 50 18.8 102.2 50 18.5 100.5 50
1 18.4 50 18.6 101.1 50 18.8 102.2 50 18.5 100.5 50
2 19.4 50 19.3 99.5 50 19.7 101.5 50 19.7 101.5 50
3 20.5 50 20.4 99.5 50 20.8 101.5 50 20.7 101.0 50
4 21.2 50 21.1 99.5 50 21.5 101.4 50 21.3 100.5 50
5 22.2 50 22.2 100.0 50 22.7 102.3 50 22.5 101.4 50
6 23.4 50 23.3 99.6 50 23.9 102.1 50 23.5 100.4 50
7 24.3 50 24.2 99.6 50 24.7 101.6 50 24.4 100.4 50
8 24.6 50 24.9 101.2 50 25.4 103.3 50 24.9 101.2 50
9 25.7 50 25.7 100.0 50 26.3 102.3 50 25.8 100.4 50
10 26.7 50 26.1 97.8 50 27.4 102.6 50 26.7 100.0 50
11 28.0 50 27.8 99.3 50 28.3 101.1 50 27.8 99.3 50
12 28.4 50 28.3 99.6 50 29.4 103.5 50 27.9 98.2 50
13 29.8 50 29.0 97.3 50 30.0 100.7 50 29.2 98.0 50
17 34.8 50 34.0 97.7 50 34.7 99.7 50 33.0 94.8 50
21 38.9 50 38.2 98.2 50 38.4 98.7 50 36.3 93.3 50
25 44.0 50 44.0 100.0 50 43.5 98.9 50 42.1 95.7 50
29 47.6 50 47.9 100.6 50 46.7 98.1 50 45.0 94.5 50
33 49.7 50 50.4 101.4 50 49.2 99.0 50 47.1 94.8 50
37 53.5 50 54.6 102.1 50 52.4 97.9 50 50.4 94.2 50
41 56.2 50 56.2 100.0 50 54.3 96.6 50 52.4 93.2 49
45 57.0 50 57.9 101.6 50 55.5 97.4 50 53.9 94.6 49
49 58.0 50 59.1 101.9 50 57.3 98.8 50 55.6 95.9 49
53 60.1 50 60.4 100.5 50 59.2 98.5 50 57.3 95.3 49
57 60.9 50 60.6 99.5 49 59.8 98.2 50 58.2 95.6 49
61 63.4 50 62.1 97.9 49 61.2 96.5 50 60.0 94.6 49
65 63.5 50 62.3 98.1 49 62.0 97.6 50 61.0 96.1 48
69 64.1 49 62.7 97.8 49 62.5 97.5 50 61.2 95.5 48
73 63.8 49 63.1 98.9 47 62.9 98.6 49 61.1 95.8 48
77 64.3 48 63.6 98.9 47 63.3 98.4 48 62.0 96.4 48
81 63.2 47 63.1 99.8 47 61.3 97.0 47 60.7 96.0 48
85 63.1 46 61.8 97.9 46 61.8 97.9 46 59.2 93.8 48
89 63.2 45 62.5 98.9 44 61.4 97.2 45 60.4 95.6 46
93 63.6 44 63.9 100.5 44 61.9 97.3 40 60.9 95.8 44
97 60.8 42 62.1 102.1 43 59.2 97.4 38 58.3 95.9 42
101 59.0 42 59.5 100.8 40 57.9 98.1 35 56.6 95.9 38
TERM. SAC. 38 35 32 32
==========================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.