TDMS Study 97013-96 Pathology Tables
NTP FEED, WATER, AND COMPOUND CONSUMPTION TABLE REPORT: EISRPT39 LAB: Battelle Columbus WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) DATE: 10/08/03 EXPERIMENT: 97013 TEST: 96 TIME: 15:23:49 CAGES FROM 0000 TO LAST CAGE PAGE: 1 TEST TYPE: 26-39 WEEKS ROUTE: DOSED WATER NTP: C97013J ------------------------------------------------------------------------------------------------------------------------------------ FINAL/MICE REASONS FOR REMOVAL: ALL REMOVAL DATE RANGE: ALL TREATMENT GROUPS: INCLUDE ALL NTP FEED, WATER, AND COMPOUND CONSUMPTION TABLE REPORT: EISRPT39 LAB: BATTELLE COLUMBUS WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) DATE: 10/08/03 EXPERIMENT: 97013 TEST: 96 TIME: 15:32:26 TEST TYPE: 26 ROUTE: DOSED WATER NTP: 97013J CONT: NO1-ES-65406 CAS: 75-27-4 WATER AND COMPOUND CONSUMPTION BY MALE MICE IN THE 26 DOSED WATER STUDY OF WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) ================================================================================================================================== 0 MG/L 175 MG/L 350 MG/L 700 MG/L ---------------- --------------------------------- --------------------------------- --------------------------------- DOSE/ DOSE/ DOSE/ GRAMS BODY GRAMS BODY CONTROL GRAMS BODY CONTROL GRAMS BODY CONTROL WATER/ WEIGHT WATER/ WEIGHT WATER (B) DOSE/ WATER/ WEIGHT WATER (B) DOSE/ WATER/ WEIGHT WATER (B) DOSE/ WEEK DAY(A) (GRAMS) DAY(A) (GRAMS) (GRAMS) DAY(C) DAY(A) (GRAMS) (GRAMS) DAY(C) DAY(A) (GRAMS) (GRAMS) DAY(C) ================================================================================================================================== 1 3.5 23.0 1.8 22.5 0.51 14 2.2 23.0 0.63 34 0.9 22.8 0.26 28 2 3.5 23.8 2.8 23.3 0.80 21 2.7 23.0 0.77 40 2.2 20.3 0.63 74 3 3.2 24.8 2.7 24.2 0.84 20 2.6 24.1 0.81 38 2.2 22.8 0.69 67 4 3.3 25.5 2.8 25.4 0.85 20 2.7 25.5 0.82 38 2.3 24.3 0.70 66 5 3.3 26.3 2.9 26.5 0.88 19 2.7 26.0 0.82 36 2.2 24.6 0.67 64 6 2.3 27.2 2.1 27.5 0.91 14 2.0 26.4 0.87 26 1.7 25.0 0.74 48 7 3.4 29.1 3.0 28.9 0.88 18 2.8 27.4 0.82 35 2.6 25.7 0.76 72 8 3.7 29.4 3.2 29.8 0.86 19 3.2 28.2 0.86 39 2.7 27.1 0.73 70 9 3.6 31.7 3.0 31.0 0.83 17 3.0 28.9 0.83 37 2.5 28.2 0.69 63 10 3.7 33.5 3.2 32.3 0.86 17 3.1 30.8 0.84 35 2.8 29.5 0.76 66 11 3.7 34.6 3.1 32.7 0.84 17 3.1 30.9 0.84 35 2.6 30.3 0.70 59 12 3.6 35.7 2.9 34.8 0.81 15 3.1 32.4 0.86 33 2.6 31.7 0.72 57 13 3.6 36.8 3.3 35.1 0.92 16 3.0 33.5 0.83 32 2.7 31.3 0.75 60 14 3.7 37.4 3.0 36.2 0.81 15 3.0 33.9 0.81 31 2.7 31.8 0.73 59 15 3.9 38.2 3.0 37.0 0.77 14 3.1 34.8 0.79 31 2.6 32.9 0.67 56 16 4.0 39.3 3.0 38.0 0.75 14 3.2 35.6 0.80 31 2.7 33.5 0.68 57 17 4.0 40.5 3.3 39.8 0.83 15 3.3 37.0 0.83 31 3.0 34.4 0.75 61 18 4.0 41.5 3.1 40.2 0.78 13 3.3 38.0 0.83 31 3.3 34.5 0.83 67 19 4.0 41.3 3.2 41.3 0.80 14 3.2 38.3 0.80 30 2.8 35.7 0.70 56 20 4.3 41.5 3.2 41.8 0.74 13 3.2 38.9 0.74 28 2.9 36.6 0.67 56 21 4.0 43.0 3.1 42.3 0.78 13 3.2 39.1 0.80 29 2.7 37.2 0.68 51 22 4.4 43.7 3.1 43.5 0.70 13 3.3 40.2 0.75 29 2.9 36.6 0.66 56 23 4.3 44.9 3.1 43.9 0.72 12 3.1 41.5 0.72 26 3.1 37.1 0.72 58 24 4.1 45.8 2.8 44.5 0.68 11 3.1 41.6 0.76 26 2.6 37.6 0.63 49 25 4.0 46.0 3.1 44.6 0.78 12 3.4 40.7 0.85 29 2.9 36.4 0.73 56 26 4.1 46.8 3.2 44.3 0.78 13 3.2 41.1 0.78 27 2.8 39.7 0.68 50 27 4.4 47.4 3.2 45.4 0.73 12 3.4 41.5 0.77 29 3.0 40.4 0.68 53 28 4.2 47.9 3.2 45.8 0.76 12 3.4 42.5 0.81 28 3.2 39.6 0.76 57 29 4.3 48.2 3.1 46.3 0.72 12 3.4 42.9 0.79 28 3.4 41.0 0.79 58 30 3.9 48.3 3.0 46.4 0.77 11 3.2 41.6 0.82 26 2.8 41.4 0.72 47 31 4.7 47.2 3.4 46.2 0.72 13 3.4 42.6 0.72 28 3.1 40.9 0.66 52 32 4.4 47.0 3.2 46.7 0.73 12 3.4 44.3 0.77 26 2.9 42.4 0.66 47 33 5.0 49.1 3.4 47.5 0.68 12 3.4 44.1 0.68 27 2.9 43.0 0.58 48 34 4.6 49.8 3.4 47.7 0.74 13 3.4 44.9 0.74 27 3.2 44.1 0.70 50 35 4.6 50.1 3.3 47.7 0.72 12 3.5 45.3 0.76 27 3.0 43.4 0.65 49 36 4.8 49.9 3.5 48.3 0.73 13 3.7 45.4 0.77 29 2.9 43.0 0.60 48 37 4.9 49.7 3.2 47.2 0.65 12 3.5 45.5 0.71 27 2.9 44.5 0.59 45 38 4.9 50.3 3.5 48.7 0.71 12 3.7 46.5 0.76 28 3.1 45.0 0.63 48 39 4.7 50.9 3.6 48.2 0.77 13 3.6 46.7 0.77 27 3.4 44.5 0.72 53 ================================================================================================================================== WATER AND COMPOUND CONSUMPTION BY MALE MICE IN THE 26 DOSED WATER STUDY OF WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) ================================================================================================================================== 0 MG/L 175 MG/L 350 MG/L 700 MG/L ---------------- --------------------------------- --------------------------------- --------------------------------- DOSE/ DOSE/ DOSE/ GRAMS BODY GRAMS BODY CONTROL GRAMS BODY CONTROL GRAMS BODY CONTROL WATER/ WEIGHT WATER/ WEIGHT WATER (B) DOSE/ WATER/ WEIGHT WATER (B) DOSE/ WATER/ WEIGHT WATER (B) DOSE/ WEEK DAY(A) (GRAMS) DAY(A) (GRAMS) (GRAMS) DAY(C) DAY(A) (GRAMS) (GRAMS) DAY(C) DAY(A) (GRAMS) (GRAMS) DAY(C) ================================================================================================================================== 40 4.6 51.0 3.3 48.5 0.72 12 3.5 45.8 0.76 27 3.4 44.3 0.74 53 41 4.7 51.3 3.5 48.8 0.74 12 3.5 46.1 0.74 27 3.5 44.3 0.74 55 42 4.6 51.6 3.3 49.1 0.72 12 3.6 45.6 0.78 28 3.4 43.7 0.74 54 1 TO 13 WEEKS ---------------- MEAN 3.4 29.3 2.8 28.8 0.83 17 2.8 27.7 0.82 35 2.3 26.4 0.68 61 SD(D) 0.4 0.4 0.10 2 0.4 0.06 4 0.5 0.13 12 CV(E) 11.2 14.6 12.2 13.5 13.1 7.6 10.3 22.4 19.5 19.7 14 TO 52 WEEKS ---------------- MEAN 4.4 46.2 3.2 44.7 0.74 13 3.3 41.8 0.77 28 3.0 39.6 0.69 53 SD(D) 0.4 0.2 0.04 1 0.2 0.04 2 0.2 0.06 5 CV(E) 8.1 5.5 5.3 7.2 5.6 5.0 5.9 8.2 8.3 9.3 ================================================================================================================================== (A) GRAMS OF WATER CONSUMED PER ANIMAL PER DAY. (B) GRAMS OF WATER PER DAY FOR THE DOSED GROUP DIVIDED BY THAT FOR THE CONTROLS. (C) MILLIGRAMS OF COMPOUND CONSUMED PER DAY PER KILOGRAM BODY WEIGHT. (D) STANDARD DEVIATION OF WEEKLY MEAN. (E) COEFFICIENT OF VARIATION = (STANDARD DEVIATION / MEAN) X 100. WATER AND COMPOUND CONSUMPTION BY FEMALE MICE IN THE 26 DOSED WATER STUDY OF WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) ================================================================================================================================== 0 MG/L 175 MG/L 350 MG/L 700 MG/L ---------------- --------------------------------- --------------------------------- --------------------------------- DOSE/ DOSE/ DOSE/ GRAMS BODY GRAMS BODY CONTROL GRAMS BODY CONTROL GRAMS BODY CONTROL WATER/ WEIGHT WATER/ WEIGHT WATER (B) DOSE/ WATER/ WEIGHT WATER (B) DOSE/ WATER/ WEIGHT WATER (B) DOSE/ WEEK DAY(A) (GRAMS) DAY(A) (GRAMS) (GRAMS) DAY(C) DAY(A) (GRAMS) (GRAMS) DAY(C) DAY(A) (GRAMS) (GRAMS) DAY(C) ================================================================================================================================== 1 3.6 18.8 1.9 18.7 0.53 18 1.4 18.4 0.39 26 1.8 19.1 0.50 66 2 3.7 19.5 2.8 19.6 0.76 25 3.2 18.7 0.86 59 3.0 19.4 0.81 108 3 3.7 20.0 3.1 20.5 0.84 26 3.1 19.5 0.84 55 3.1 19.6 0.84 109 4 3.6 21.0 3.2 21.4 0.89 26 3.4 20.7 0.94 57 3.3 21.5 0.92 108 5 4.0 21.3 3.6 21.5 0.90 29 3.8 21.0 0.95 63 3.7 21.7 0.93 120 6 2.9 22.2 2.3 22.4 0.79 18 2.7 22.0 0.93 43 2.9 22.7 1.00 89 7 4.1 22.5 3.7 22.8 0.90 29 3.8 21.8 0.93 61 4.3 23.1 1.05 130 8 4.2 23.0 3.8 23.5 0.90 28 3.8 22.8 0.90 58 4.0 23.5 0.95 118 9 3.8 23.7 3.9 23.6 1.03 29 3.7 23.3 0.97 56 4.1 23.9 1.08 121 10 4.0 24.2 4.0 24.4 1.00 28 3.7 23.9 0.93 54 4.1 24.9 1.03 116 11 4.2 24.0 3.7 25.1 0.88 26 3.5 24.0 0.83 52 4.0 24.6 0.95 113 12 4.4 23.9 3.7 25.9 0.84 25 3.7 24.3 0.84 54 4.3 24.8 0.98 123 13 4.3 24.9 3.7 26.5 0.86 25 3.6 25.3 0.84 50 4.2 25.3 0.98 115 14 5.0 25.6 3.8 26.9 0.76 25 3.8 25.6 0.76 52 4.3 26.1 0.86 116 15 4.3 25.6 3.8 27.1 0.88 24 3.7 25.6 0.86 51 4.1 26.1 0.95 111 16 4.6 25.8 3.8 27.2 0.83 24 3.8 26.5 0.83 50 4.3 26.4 0.93 114 17 4.7 27.0 4.2 28.4 0.89 26 3.8 27.4 0.81 48 4.5 27.3 0.96 116 18 4.7 27.6 3.8 29.0 0.81 23 3.8 27.8 0.81 48 4.4 28.3 0.94 109 19 4.9 27.9 4.1 29.4 0.84 24 3.7 28.0 0.76 46 4.4 28.9 0.90 107 20 4.5 28.7 4.1 30.6 0.91 23 3.7 28.7 0.82 45 4.4 28.7 0.98 107 21 4.4 28.7 4.0 30.0 0.91 23 3.8 28.4 0.86 47 4.5 28.3 1.02 112 22 4.4 29.5 4.2 31.0 0.95 24 3.9 29.6 0.89 46 4.4 30.0 1.00 104 23 4.5 30.4 3.9 32.1 0.87 21 3.7 30.8 0.82 42 4.4 31.0 0.98 100 24 4.0 30.8 3.4 32.5 0.85 18 3.7 31.2 0.93 42 4.1 32.1 1.03 90 25 4.3 31.5 4.0 32.0 0.93 22 3.8 30.9 0.88 43 4.5 32.0 1.05 99 26 4.3 32.1 3.8 31.9 0.88 21 3.6 32.3 0.84 39 4.2 32.3 0.98 91 27 4.8 32.9 4.0 31.6 0.83 22 3.7 32.8 0.77 40 4.4 33.6 0.92 92 28 4.5 34.0 3.9 34.3 0.87 20 3.7 33.8 0.82 38 4.3 35.3 0.96 85 29 4.6 35.3 4.1 35.3 0.89 20 3.7 35.3 0.80 37 4.3 35.2 0.93 86 30 4.5 36.3 3.8 36.3 0.84 18 3.5 36.5 0.78 34 3.8 36.9 0.84 72 31 4.5 35.4 4.1 36.1 0.91 20 3.7 36.4 0.82 36 4.2 34.5 0.93 86 32 4.8 37.0 4.0 37.3 0.83 19 3.5 36.6 0.73 33 4.6 34.4 0.96 95 33 4.8 37.8 4.0 37.8 0.83 18 3.7 37.4 0.77 35 5.0 36.0 1.04 96 34 5.1 38.3 4.1 39.3 0.80 18 3.7 39.1 0.73 33 4.5 38.6 0.88 82 35 5.3 39.0 4.0 39.7 0.75 18 3.7 38.9 0.70 33 4.4 39.3 0.83 78 36 5.0 39.7 3.9 40.4 0.78 17 3.8 38.9 0.76 34 4.3 39.9 0.86 76 37 5.3 39.4 4.0 40.8 0.75 17 3.7 38.9 0.70 34 4.2 39.5 0.79 74 38 5.6 40.8 4.1 41.4 0.73 17 3.7 40.2 0.66 32 4.2 39.4 0.75 75 39 5.0 41.5 3.8 42.3 0.76 16 3.8 41.2 0.76 32 4.2 40.0 0.84 73 ================================================================================================================================== WATER AND COMPOUND CONSUMPTION BY FEMALE MICE IN THE 26 DOSED WATER STUDY OF WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) ================================================================================================================================== 0 MG/L 175 MG/L 350 MG/L 700 MG/L ---------------- --------------------------------- --------------------------------- --------------------------------- DOSE/ DOSE/ DOSE/ GRAMS BODY GRAMS BODY CONTROL GRAMS BODY CONTROL GRAMS BODY CONTROL WATER/ WEIGHT WATER/ WEIGHT WATER (B) DOSE/ WATER/ WEIGHT WATER (B) DOSE/ WATER/ WEIGHT WATER (B) DOSE/ WEEK DAY(A) (GRAMS) DAY(A) (GRAMS) (GRAMS) DAY(C) DAY(A) (GRAMS) (GRAMS) DAY(C) DAY(A) (GRAMS) (GRAMS) DAY(C) ================================================================================================================================== 40 4.8 42.4 3.6 43.5 0.75 15 3.6 41.2 0.75 30 4.2 39.7 0.88 73 41 5.1 43.6 3.9 44.2 0.76 16 3.9 42.5 0.76 32 4.6 39.9 0.90 80 42 4.4 44.5 3.6 43.6 0.82 15 3.7 43.9 0.84 29 4.3 40.4 0.98 74 1 TO 13 WEEKS ---------------- MEAN 3.9 22.2 3.3 22.8 0.86 25 3.3 22.0 0.86 53 3.6 22.6 0.92 110 SD(D) 0.4 0.7 0.12 4 0.7 0.15 10 0.7 0.15 17 CV(E) 10.1 19.6 14.3 14.8 20.6 17.4 18.3 20.8 16.0 15.1 14 TO 52 WEEKS ---------------- MEAN 4.7 34.1 3.9 34.9 0.84 20 3.7 34.0 0.79 39 4.4 33.8 0.93 92 SD(D) 0.4 0.2 0.06 3 0.1 0.06 7 0.2 0.07 15 CV(E) 7.8 4.8 7.4 16.2 2.5 7.8 17.8 4.7 8.0 16.2 ================================================================================================================================== (A) GRAMS OF WATER CONSUMED PER ANIMAL PER DAY. (B) GRAMS OF WATER PER DAY FOR THE DOSED GROUP DIVIDED BY THAT FOR THE CONTROLS. (C) MILLIGRAMS OF COMPOUND CONSUMED PER DAY PER KILOGRAM BODY WEIGHT. (D) STANDARD DEVIATION OF WEEKLY MEAN. (E) COEFFICIENT OF VARIATION = (STANDARD DEVIATION / MEAN) X 100. DIAGNOSTIC TRAILER REPORT WATER AND COMPOUND CONSUMPTION BY MALE MICE IN THE 26 DOSED WATER STUDY OF WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) ========================================================================================================= 0 MG/L 175 MG/L 350 MG/L 700 MG/L ---------------------- ---------------------- ---------------------- ---------------------- DAILY WATER BODY NUM DAILY WATER BODY NUM DAILY WATER BODY NUM DAILY WATER BODY NUM WEEK WATER HOURS WGT WGTS WATER HOURS WGT WGTS WATER HOURS WGT WGTS WATER HOURS WGT WGTS ========================================================================================================== B 23.0 10 22.5 10 23.0 10 22.8 10 1 3.5 710 23.0 10 1.8 689 22.5 10 2.2 685 23.0 10 0.9 685 22.8 10 2 3.5 1612 23.8 10 2.8 1620 23.3 10 2.7 1661 23.0 10 2.2 1685 20.3 10 3 3.2 1527 24.8 10 2.7 1658 24.2 10 2.6 1605 24.1 10 2.2 1660 22.8 10 4 3.3 1696 25.5 10 2.8 1696 25.4 10 2.7 1700 25.5 10 2.3 1620 24.3 10 5 3.3 958 26.3 10 2.9 970 26.5 10 2.7 863 26.0 10 2.2 869 24.6 10 6 2.3 2183 27.2 10 2.1 2196 27.5 10 2.0 2182 26.4 10 1.7 2020 25.0 10 7 3.4 1526 29.1 10 3.0 1594 28.9 10 2.8 1645 27.4 10 2.6 1426 25.7 10 8 3.7 1645 29.4 10 3.2 1634 29.8 10 3.2 1641 28.2 10 2.7 1635 27.1 10 9 3.6 1695 31.7 10 3.0 1700 31.0 10 3.0 1690 28.9 10 2.5 1695 28.2 10 10 3.7 1680 33.5 10 3.2 1472 32.3 10 3.1 1680 30.8 10 2.8 1624 29.5 10 11 3.7 1700 34.6 10 3.1 1343 32.7 10 3.1 1601 30.9 10 2.6 1606 30.3 10 12 3.6 1563 35.7 10 2.9 1443 34.8 10 3.1 1660 32.4 10 2.6 1355 31.7 10 13 3.6 1589 36.8 10 3.3 1585 35.1 10 3.0 1690 33.5 10 2.7 1516 31.3 10 14 3.7 1596 37.4 10 3.0 1657 36.2 10 3.0 1700 33.9 10 2.7 1358 31.8 10 15 3.9 1665 38.2 10 3.0 1670 37.0 10 3.1 1591 34.8 10 2.6 1425 32.9 9 16 4.0 1670 39.3 10 3.0 1594 38.0 10 3.2 1600 35.6 10 2.7 1427 33.5 9 17 4.0 1710 40.5 10 3.3 1579 39.8 10 3.3 1700 37.0 10 3.0 1340 34.4 9 18 4.0 1593 41.5 10 3.1 1571 40.2 10 3.3 1594 38.0 10 3.3 1325 34.5 9 19 4.0 1525 41.3 10 3.2 1618 41.3 10 3.2 1666 38.3 10 2.8 1521 35.7 9 20 4.3 1587 41.5 10 3.2 1690 41.8 10 3.2 1680 38.9 10 2.9 1423 36.6 9 21 4.0 1695 43.0 10 3.1 1695 42.3 10 3.2 1549 39.1 10 2.7 1448 37.2 9 22 4.4 1432 43.7 10 3.1 1512 43.5 10 3.3 1660 40.2 10 2.9 1212 36.6 9 23 4.3 1670 44.9 10 3.1 1655 43.9 10 3.1 1597 41.5 10 3.1 1145 37.1 9 24 4.1 1705 45.8 10 2.8 1400 44.5 10 3.1 1616 41.6 10 2.6 1226 37.6 9 25 4.0 1658 46.0 10 3.1 1557 44.6 10 3.4 1466 40.7 10 2.9 1152 36.4 9 26 4.1 1536 46.8 10 3.2 1569 44.3 10 3.2 1555 41.1 10 2.8 1149 39.7 8 27 4.4 1563 47.4 10 3.2 1614 45.4 10 3.4 1605 41.5 10 3.0 1254 40.4 8 28 4.2 1670 47.9 10 3.2 1646 45.8 10 3.4 1602 42.5 10 3.2 1189 39.6 8 29 4.3 1680 48.2 10 3.1 1614 46.3 10 3.4 1680 42.9 10 3.4 1277 41.0 8 30 3.9 1690 48.3 10 3.0 1450 46.4 10 3.2 1481 41.6 10 2.8 1190 41.4 8 31 4.7 1512 47.2 10 3.4 1517 46.2 10 3.4 1680 42.6 10 3.1 1068 40.9 8 32 4.4 1397 47.0 10 3.2 1568 46.7 10 3.4 1599 44.3 10 2.9 1183 42.4 8 33 5.0 1412 49.1 9 3.4 1697 47.5 10 3.4 1671 44.1 10 2.9 1344 43.0 8 34 4.6 1500 49.8 9 3.4 1568 47.7 10 3.4 1523 44.9 10 3.2 1328 44.1 8 35 4.6 1361 50.1 9 3.3 1660 47.7 10 3.5 1594 45.3 10 3.0 1211 43.4 8 36 4.8 1516 49.9 9 3.5 1660 48.3 10 3.7 1680 45.4 10 2.9 973 43.0 8 37 4.9 1314 49.7 9 3.2 1587 47.2 10 3.5 1590 45.5 10 2.9 1187 44.5 7 38 4.9 1508 50.3 9 3.5 1613 48.7 10 3.7 1654 46.5 10 3.1 925 45.0 7 39 4.7 1417 50.9 9 3.6 1448 48.2 10 3.6 1562 46.7 10 3.4 839 44.5 7 40 4.6 1419 51.0 9 3.3 1710 48.5 10 3.5 1363 45.8 10 3.4 810 44.3 7 41 4.7 1440 51.3 9 3.5 1505 48.8 10 3.5 1140 46.1 9 3.5 897 44.3 7 42 4.6 1535 51.6 9 3.3 1581 49.1 10 3.6 1317 45.6 9 3.4 1111 43.7 7 43 4.3 873 3.1 860 3.3 852 3.1 486 MEAN BODY WGT FOR WEEKS 1 TO 13 29.3 28.8 27.7 26.4 14 TO 52 46.2 44.7 41.8 39.6 ========================================================================================================= (B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT. DIAGNOSTIC TRAILER REPORT WATER AND COMPOUND CONSUMPTION BY FEMALE MICE IN THE 26 DOSED WATER STUDY OF WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) ========================================================================================================= 0 MG/L 175 MG/L 350 MG/L 700 MG/L ---------------------- ---------------------- ---------------------- ---------------------- DAILY WATER BODY NUM DAILY WATER BODY NUM DAILY WATER BODY NUM DAILY WATER BODY NUM WEEK WATER HOURS WGT WGTS WATER HOURS WGT WGTS WATER HOURS WGT WGTS WATER HOURS WGT WGTS ========================================================================================================== B 18.8 10 18.7 10 18.4 10 19.1 10 1 3.6 685 18.8 10 1.9 715 18.7 10 1.4 710 18.4 10 1.8 710 19.1 10 2 3.7 1651 19.5 10 2.8 1638 19.6 10 3.2 1582 18.7 10 3.0 1632 19.4 10 3 3.7 1573 20.0 10 3.1 1640 20.5 10 3.1 1611 19.5 10 3.1 1690 19.6 10 4 3.6 1529 21.0 10 3.2 1695 21.4 10 3.4 1700 20.7 10 3.3 1602 21.5 10 5 4.0 960 21.3 10 3.6 965 21.5 10 3.8 970 21.0 10 3.7 965 21.7 10 6 2.9 2038 22.2 10 2.3 2111 22.4 10 2.7 2173 22.0 10 2.9 1964 22.7 10 7 4.1 1720 22.5 10 3.7 1476 22.8 10 3.8 1379 21.8 10 4.3 1619 23.1 10 8 4.2 1566 23.0 10 3.8 1636 23.5 10 3.8 1640 22.8 10 4.0 1635 23.5 10 9 3.8 1525 23.7 10 3.9 1645 23.6 10 3.7 1603 23.3 10 4.1 1476 23.9 9 10 4.0 1456 24.2 10 4.0 1434 24.4 10 3.7 1473 23.9 10 4.1 1344 24.9 9 11 4.2 1431 24.0 10 3.7 1606 25.1 10 3.5 1514 24.0 10 4.0 1193 24.6 9 12 4.4 1495 23.9 10 3.7 1591 25.9 10 3.7 1484 24.3 10 4.3 1422 24.8 9 13 4.3 1547 24.9 10 3.7 1685 26.5 10 3.6 1690 25.3 10 4.2 1521 25.3 9 14 5.0 1685 25.6 10 3.8 1685 26.9 10 3.8 1619 25.6 10 4.3 1515 26.1 9 15 4.3 1419 25.6 10 3.8 1673 27.1 10 3.7 1588 25.6 10 4.1 1440 26.1 9 16 4.6 1403 25.8 10 3.8 1494 27.2 10 3.8 1552 26.5 10 4.3 1503 26.4 9 17 4.7 1578 27.0 10 4.2 1608 28.4 10 3.8 1552 27.4 10 4.5 1408 27.3 9 18 4.7 1498 27.6 10 3.8 1567 29.0 10 3.8 1597 27.8 10 4.4 1499 28.3 9 19 4.9 1624 27.9 10 4.1 1690 29.4 10 3.7 1481 28.0 10 4.4 1327 28.9 9 20 4.5 1656 28.7 10 4.1 1610 30.6 10 3.7 1587 28.7 10 4.4 1517 28.7 9 21 4.4 1694 28.7 10 4.0 1622 30.0 10 3.8 1700 28.4 10 4.5 1524 28.3 9 22 4.4 1293 29.5 10 4.2 1551 31.0 10 3.9 1609 29.6 10 4.4 1336 30.0 9 23 4.5 1665 30.4 10 3.9 1564 32.1 10 3.7 1650 30.8 10 4.4 1428 31.0 9 24 4.0 1634 30.8 10 3.4 1492 32.5 10 3.7 1331 31.2 10 4.1 1196 32.1 9 25 4.3 1654 31.5 10 4.0 1223 32.0 10 3.8 1408 30.9 10 4.5 1363 32.0 9 26 4.3 1603 32.1 10 3.8 1363 31.9 10 3.6 1660 32.3 10 4.2 1411 32.3 9 27 4.8 1545 32.9 10 4.0 1445 31.6 10 3.7 1494 32.8 10 4.4 1279 33.6 9 28 4.5 1503 34.0 10 3.9 1435 34.3 9 3.7 1670 33.8 10 4.3 1335 35.3 9 29 4.6 1515 35.3 10 4.1 1245 35.3 9 3.7 1578 35.3 10 4.3 1411 35.2 9 30 4.5 1695 36.3 10 3.8 1384 36.3 9 3.5 1327 36.5 10 3.8 1336 36.9 9 31 4.5 1581 35.4 10 4.1 1367 36.1 9 3.7 1369 36.4 10 4.2 941 34.5 9 32 4.8 1568 37.0 10 4.0 1282 37.3 9 3.5 1624 36.6 10 4.6 1068 34.4 9 33 4.8 1615 37.8 10 4.0 1470 37.8 9 3.7 1720 37.4 10 5.0 1497 36.0 9 34 5.1 1406 38.3 10 4.1 1308 39.3 9 3.7 1524 39.1 10 4.5 1328 38.6 8 35 5.3 1665 39.0 10 4.0 1470 39.7 9 3.7 1566 38.9 10 4.4 1332 39.3 8 36 5.0 1596 39.7 10 3.9 1374 40.4 9 3.8 1197 38.9 10 4.3 1344 39.9 8 37 5.3 1398 39.4 10 4.0 1429 40.8 9 3.7 1410 38.9 10 4.2 1211 39.5 8 38 5.6 1516 40.8 10 4.1 1227 41.4 9 3.7 1541 40.2 10 4.2 1183 39.4 8 39 5.0 1633 41.5 10 3.8 1494 42.3 9 3.8 1369 41.2 10 4.2 1128 40.0 8 40 4.8 1514 42.4 10 3.6 1368 43.5 9 3.6 1421 41.2 10 4.2 1270 39.7 8 41 5.1 1483 43.6 10 3.9 1270 44.2 9 3.9 1570 42.5 10 4.6 1181 39.9 8 42 4.4 1290 44.5 9 3.6 1314 43.6 9 3.7 1338 43.9 10 4.3 929 40.4 8 43 4.0 682 3.3 683 3.1 882 3.8 639 MEAN BODY WGT FOR WEEKS 1 TO 13 22.2 22.8 22.0 22.6 14 TO 52 34.1 34.9 34.0 33.8 ========================================================================================================= (B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.