TDMS Study 97013-05 Pathology Tables
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: Battelle Columbus WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) DATE: 06/11/04
EXPERIMENT: 97013 TEST: 05 TIME: 08:08:00
CAGES FROM 0000 TO LAST CAGE PAGE: 1
TEST TYPE: SUBCHRON 26-WEEK ROUTE: DOSED WATER NTP: C97013E
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REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: BATTELLE COLUMBUS WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) DATE: 06/11/04
EXPERIMENT: 97013 TEST: 05 TIME: 8:12:58
SPECIES: MICE, TG.AC HEMI
TEST TYPE: SUBCHRONIC (26-WEEK) ROUTE: DOSED WATER NTP: 97013E
CONT: NO1-ES-65406 CAS: 75-27-4
MEAN BODY WEIGHTS AND SURVIVAL OF MALE MICE IN THE
SUBCHRONIC (26-WEEK) DOSED WATER STUDY OF WATER DISINFECTION MODEL (BROMODICHLOROMETHANE)
===================================================================================================================================
WEEK 0 MG/L 175 MG/L 350 MG/L 700 MG/L TPA
---------------- ---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
==================================================================================================================================
B 23.1 15 22.6 97.8 15 22.6 97.8 15 22.7 98.3 15 21.4 92.6 15
1 23.1 15 22.6 97.8 15 22.6 97.8 15 22.7 98.3 15 21.4 92.6 15
2 24.6 15 24.1 98.0 15 23.2 94.3 15 20.8 84.6 15 22.6 91.9 15
3 26.1 15 25.7 98.5 15 25.0 95.8 15 23.9 91.6 15 24.2 92.7 15
4 26.8 15 26.7 99.6 15 25.8 96.3 15 25.9 96.6 15 25.2 94.0 15
5 27.8 15 27.7 99.6 15 27.3 98.2 15 26.5 95.3 15 26.3 94.6 15
6 29.4 15 28.9 98.3 15 28.1 95.6 15 27.3 92.9 15 26.8 91.2 15
7 30.0 15 29.4 98.0 15 28.6 95.3 15 27.4 91.3 15 27.2 90.7 15
8 30.2 15 29.9 99.0 15 28.9 95.7 15 28.1 93.0 15 27.5 91.1 15
9 31.0 15 30.5 98.4 15 29.5 95.2 15 28.7 92.6 15 28.4 91.6 15
10 32.0 15 31.1 97.2 15 30.1 94.1 15 29.3 91.6 15 29.2 91.3 14
11 32.8 15 31.4 95.7 15 30.0 91.5 15 30.2 92.1 15 29.1 88.7 12
12 32.6 15 32.2 98.8 14 30.6 93.9 15 30.7 94.2 15 28.2 86.5 7
13 34.2 15 33.1 96.8 14 31.4 91.8 15 31.8 93.0 15 30.0 87.7 5
14 34.9 15 33.5 96.0 14 31.6 90.5 15 32.1 92.0 15 30.3 86.8 3
15 35.2 15 33.6 95.5 14 31.3 88.9 15 32.1 91.2 15
16 35.7 15 34.5 96.6 13 31.9 89.4 15 33.1 92.7 15
17 35.8 15 34.7 96.9 13 32.0 89.4 15 32.8 91.6 15
18 35.9 15 35.0 97.5 13 32.1 89.4 15 33.1 92.2 15
19 35.6 15 34.6 97.2 13 32.7 91.9 15 32.9 92.4 15
20 36.9 14 35.4 95.9 13 33.5 90.8 15 32.7 88.6 15
21 37.6 14 36.4 96.8 12 34.7 92.3 14 32.6 86.7 15
22 38.4 14 37.9 98.7 12 34.9 90.9 14 33.2 86.5 15
23 39.2 14 38.7 98.7 12 35.6 90.8 14 34.9 89.0 14
24 39.6 13 39.9 100.8 12 35.9 90.7 14 36.2 91.4 14
25 40.2 13 40.2 100.0 12 37.3 92.8 12 35.9 89.3 14
26 41.0 13 40.4 98.5 12 38.3 93.4 12 36.5 89.0 14
TERM. SAC. 13 12 12 14 0
===================================================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.
MEAN BODY WEIGHTS AND SURVIVAL OF FEMALE MICE IN THE
SUBCHRONIC (26-WEEK) DOSED WATER STUDY OF WATER DISINFECTION MODEL (BROMODICHLOROMETHANE)
===================================================================================================================================
WEEK 0 MG/L 175 MG/L 350 MG/L 700 MG/L TPA
---------------- ---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
==================================================================================================================================
B 19.2 15 19.1 99.5 15 19.0 99.0 15 18.9 98.4 15 18.4 95.8 15
1 19.2 15 19.1 99.5 15 19.0 99.0 15 18.9 98.4 15 18.4 95.8 15
2 20.0 15 20.3 101.5 15 20.2 101.0 15 20.2 101.0 15 19.3 96.5 15
3 21.2 15 21.4 100.9 15 21.3 100.5 15 21.4 100.9 15 20.2 95.3 15
4 22.3 15 22.3 100.0 15 22.3 100.0 15 22.3 100.0 15 21.8 97.8 15
5 23.2 15 23.1 99.6 15 22.7 97.8 15 22.7 97.8 15 22.9 98.7 15
6 24.2 15 24.1 99.6 15 23.6 97.5 14 23.8 98.3 15 23.1 95.5 15
7 24.6 15 24.3 98.8 15 23.9 97.2 14 23.8 96.7 15 23.5 95.5 15
8 24.5 15 24.7 100.8 15 24.4 99.6 14 24.0 98.0 15 23.8 97.1 15
9 24.8 14 25.8 104.0 15 24.8 100.0 14 25.0 100.8 15 24.0 96.8 15
10 25.4 13 25.6 100.8 15 25.1 98.8 14 25.3 99.6 15 24.5 96.5 15
11 24.5 13 27.1 110.6 15 25.5 104.1 14 25.8 105.3 15 24.4 99.6 13
12 25.3 13 27.2 107.5 13 26.2 103.6 14 26.2 103.6 15 24.6 97.2 10
13 26.3 13 28.2 107.2 13 26.7 101.5 14 26.8 101.9 15 25.4 96.6 5
14 26.4 13 28.5 108.0 13 26.9 101.9 14 26.8 101.5 15 25.4 96.2 5
15 26.6 13 29.0 109.0 13 27.8 104.5 14 27.9 104.9 15 25.2 94.7 3
16 27.6 13 29.5 106.9 13 28.0 101.4 14 28.1 101.8 15 25.4 92.0 3
17 27.0 11 29.1 107.8 13 27.8 103.0 14 28.2 104.4 15 25.2 93.3 2
18 27.5 11 30.4 110.5 13 27.8 101.1 14 28.4 103.3 15 27.5 100.0 2
19 27.9 11 30.5 109.3 13 29.0 103.9 13 28.6 102.5 15 26.7 95.7 2
20 29.3 11 31.0 105.8 13 29.8 101.7 13 29.5 100.7 15 26.8 91.5 2
21 29.2 11 31.6 108.2 13 29.9 102.4 13 30.1 103.1 15
22 29.5 10 31.9 108.1 13 30.7 104.1 13 30.7 104.1 15
23 29.9 10 33.1 110.7 13 31.8 106.4 13 31.2 104.3 15
24 30.2 10 33.9 112.3 13 32.1 106.3 13 32.5 107.6 14
25 28.5 10 34.6 121.4 13 33.5 117.5 11 32.9 115.4 13
26 29.9 10 34.9 116.7 13 33.9 113.4 11 33.2 111.0 13
TERM. SAC. 10 13 11 13 0
===================================================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.