TDMS Study 97013-99 Pathology Tables
NTP EXP/TEST: 97013-99 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 1
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 11/05/03
ROUTE: SKIN APPLICATION TIME: 09:59:42
EIS REPORT 37
FACILITY: Battelle Columbus Laboratory
NTP C#: 97013F
CONTRACT NUMBER: NO1-ES-65406
CAS NUMBER: 75-27-4
ANIMAL SUPPLIER: TACONIC FARMS
CAGE RANGE: ALL
DATE RANGE: ALL
REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP EXP/TEST: 97013-99 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 2
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 11/05/03
ROUTE: SKIN APPLICATION EISRPT37 TIME: 09:59:42
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SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 2 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: FEMALE TRT: 0 MG/KG PROCEDURE SET: 2
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 97013-99 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 3
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 11/05/03
ROUTE: SKIN APPLICATION EISRPT37 TIME: 09:59:42
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SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 4 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: FEMALE TRT: 64 MG/KG PROCEDURE SET: 2
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
1259 1259 134 12/30/99 134 12/30/99 1/28 Irritation Site Of Application
REMOVED ** CID 1259 ** REASON - MSAC
196 03/01/00 Thin
196 03/01/00 Ruffled Fur
NTP EXP/TEST: 97013-99 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 4
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 11/05/03
ROUTE: SKIN APPLICATION EISRPT37 TIME: 09:59:42
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SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 6 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: FEMALE TRT: 128 MG/KG PROCEDURE SET: 2
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 97013-99 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 5
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 11/05/03
ROUTE: SKIN APPLICATION EISRPT37 TIME: 09:59:42
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SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 8 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: FEMALE TRT: 256 MG/KG PROCEDURE SET: 2
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 97013-99 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 6
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 11/05/03
ROUTE: SKIN APPLICATION EISRPT37 TIME: 09:59:42
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SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 1 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: MALE TRT: 0 MG/KG PROCEDURE SET: 1
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 97013-99 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 7
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 11/05/03
ROUTE: SKIN APPLICATION EISRPT37 TIME: 09:59:42
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SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 3 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: MALE TRT: 64 MG/KG PROCEDURE SET: 1
------------------------------------------------------------------------------------------------------------------------------------
FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
THERE WERE NO DERMAL OBSERVATIONS FOR THIS SPECIES, STRAIN, SEX, AND TREATMENT GROUP.
NTP EXP/TEST: 97013-99 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 8
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 11/05/03
ROUTE: SKIN APPLICATION EISRPT37 TIME: 09:59:42
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 5 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: MALE TRT: 128 MG/KG PROCEDURE SET: 1
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
1229 1229 169 02/03/00 176 02/10/00 2/39 Irritation Site Of Application
232 04/06/00 267 05/11/00 6/39 Papilloma Site Of Application Small 1
REMOVED ** CID 1229 ** REASON - TSAC
274 05/18/00 Papilloma Site Of Application Small 1
274 05/18/00 Papilloma Head Small 5
NTP EXP/TEST: 97013-99 WATER DISINFECTION MODEL (BROMODICHLOROMETHANE) PAGE: 9
TEST TYPE: SUBCHRON 26-WEEK DERMAL CLINICAL OBSERVATIONS AT SITE OF APPLICATION BY ANIMAL DATE: 11/05/03
ROUTE: SKIN APPLICATION EISRPT37 TIME: 09:59:42
------------------------------------------------------------------------------------------------------------------------------------
SPECIES-STRAIN: MICE-TG.AC HEMI TRT#: 7 ROOM/AREA: 235 FIRST DOSE: 08/19/99
SEX: MALE TRT: 256 MG/KG PROCEDURE SET: 1
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FIRST OCCUR'D LAST OCCUR'D FREQ/
CAGE ANIMAL DAY DATE DAY DATE TOT OBS CLINICAL OBSERVATION
---- ------ ------------- ------------- ------- ------------------------------
1240 1240 260 05/04/00 260 05/04/00 1/39 Papilloma Site Of Application Small 1
267 05/11/00 267 05/11/00 1/39 Papilloma Site Of Application Small 2
REMOVED ** CID 1240 ** REASON - TSAC
274 05/18/00 Papilloma Site Of Application Small 3
274 05/18/00 Papilloma Head Small 3
274 05/18/00 Papilloma Torso/Ventral Small 3
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