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Proflavin hydrochloride: Target Organs and Levels of Evidence for TR-005

Bioassay of Proflavine for Possible Carcinogenicity (CASRN 952-23-8)

Chemical (Study Title)
Peer Review DateRoute/Exposure LevelsStudy Laboratory
Proflavin hydrochloride
R: 0,300,600, M: 0,200,400 PPM/50 PER GROUP

Levels of Evidence

Male Rats: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Intestines: (LEIOMYOSARCOMA)
Female Rats: Negative
Male Mice: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (CARCINOMA)
Female Mice: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (CARCINOMA)