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4,4'-Sulfonyldianiline (Dapsone): Target Organs and Levels of Evidence for TR-020

Bioassay of Dapsone for Possible Carcinogenicity (CASRN 80-08-0)

Chemical (Study Title) CASRN	Peer Review Date	Route/Exposure Levels	Study Laboratory
4,4'-Sulfonyldianiline (Dapsone) 80-08-0	07/25/1977	Dosed-Feed R: 0,600,1200, M: 0,500,1000 PPM/35 PER GROUP	Southern Research Institute

Levels of Evidence

Male Rats: Positive

Type	Organ/Tissue (Lesion)
Neoplastic Lesions	Spleen: (FIBROMA, FIBROSARCOMA, SARCOMA)

4,4'-Sulfonyldianiline (Dapsone): Target Organs and Levels of Evidence for TR-020

Bioassay of Dapsone for Possible Carcinogenicity (CASRN 80-08-0)

Levels of Evidence

Male Rats: Positive

Female Rats: Negative

Male Mice: Negative

Female Mice: Negative