https://ntp.niehs.nih.gov/go/12755

Nitrofen: Target Organs and Levels of Evidence for TR-026

Bioassay of Nitrofen for Possible Carcinogenicity (CASRN 1836-75-5)

Chemical (Study Title)
CASRN
Peer Review Date Route/Exposure Levels Study Laboratory
Nitrofen
1836-75-5
09/26/1977 Dosed-Feed
MR: 0,2300,3656 (AVG), FR: 0,1300,2600 (AVG), M: 0,2348,4696 (AVG) PPM/50 PER GROUP
Hazleton, Vienna

Levels of Evidence

Male Rats: Inadequate Study
Female Rats: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Pancreas Acinar Cell: CARCINOMA
Male Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Liver: HEPATOCELLULAR CARCINOMA
  • Vascular System (Liver): HEMANGIOSARCOMA
Female Mice: Positive
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Liver: HEPATOCELLULAR CARCINOMA
  • Vascular System (Liver): HEMANGIOSARCOMA