2-Methyl-1-nitroanthraquinone: Target Organs and Levels of Evidence for TR-029
Bioassay of 2-Methyl-1-Nitroanthraquinone for Possible Carcinogenicity (CASRN 129-15-7)
Chemical (Study Title)
CASRN | Peer Review Date | Primary Uses | Route/Exposure Levels | Study Laboratory |
|---|
2-Methyl-1-nitroanthraquinone
129-15-7 | 11/28/1977 | Dye intermediate (formerly) | Dosed-Feed
0,0.06,0.12 %/50 PER GROUP | T.S.I. Mason Laboratories, Inc. |
Levels of Evidence
Male Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Liver:
(NEOPLASTIC NODULE, CARCINOMA)
- Subcutaneous Tissue:
(FIBROMA)
|
Female Rats: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Liver:
(NEOPLASTIC NODULE OR CARCINOMA)
- Subcutaneous Tissue:
(FIBROMA)
|
Male Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Vascular System (Unspecified):
HEMANGIOSARCOMA
|
Female Mice: Positive
| Type | Organ/Tissue (Lesion) |
|---|
| Neoplastic Lesions | - Vascular System (Unspecified):
HEMANGIOSARCOMA
|
